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Aliases for ZNF474 Gene

Aliases for ZNF474 Gene

  • Zinc Finger Protein 474 2 3 5
  • Testis-Specific Zinc Finger Protein 3 4
  • TSZFP 3 4
  • 4933409D10Rik 3

External Ids for ZNF474 Gene

Previous GeneCards Identifiers for ZNF474 Gene

  • GC05P121494
  • GC05P116656
  • GC05P121465

Summaries for ZNF474 Gene

GeneCards Summary for ZNF474 Gene

ZNF474 (Zinc Finger Protein 474) is a Protein Coding gene. An important paralog of this gene is ENSG00000250803.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF474 Gene

Genomics for ZNF474 Gene

Regulatory Elements for ZNF474 Gene

Enhancers for ZNF474 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ZNF474 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF474 Gene

122,129,513 bp from pter
122,153,571 bp from pter
24,059 bases
Plus strand

Genomic View for ZNF474 Gene

Genes around ZNF474 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF474 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF474 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF474 Gene

Proteins for ZNF474 Gene

  • Protein details for ZNF474 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 474
    Protein Accession:
    Secondary Accessions:
    • A8K4M0
    • Q96M07

    Protein attributes for ZNF474 Gene

    364 amino acids
    Molecular mass:
    40315 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB71507.1; Type=Frameshift; Positions=318; Evidence={ECO:0000305};

neXtProt entry for ZNF474 Gene

Post-translational modifications for ZNF474 Gene

  • Ubiquitination at Lys 327
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF474 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF474 Gene

Domains & Families for ZNF474 Gene

Gene Families for ZNF474 Gene

Protein Domains for ZNF474 Gene


Suggested Antigen Peptide Sequences for ZNF474 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 C2H2-type zinc finger.
  • Contains 1 C2H2-type zinc finger.
genes like me logo Genes that share domains with ZNF474: view

Function for ZNF474 Gene

Gene Ontology (GO) - Molecular Function for ZNF474 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF474: view

Phenotypes for ZNF474 Gene

genes like me logo Genes that share phenotypes with ZNF474: view

Animal Model Products

CRISPR Products

miRNA for ZNF474 Gene

miRTarBase miRNAs that target ZNF474

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF474 Gene

Localization for ZNF474 Gene

Subcellular locations from

Jensen Localization Image for ZNF474 Gene COMPARTMENTS Subcellular localization image for ZNF474 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZNF474 Gene

Pathways & Interactions for ZNF474 Gene

SuperPathways for ZNF474 Gene

No Data Available

Interacting Proteins for ZNF474 Gene

Gene Ontology (GO) - Biological Process for ZNF474 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZNF474 Gene

Drugs & Compounds for ZNF474 Gene

No Compound Related Data Available

Transcripts for ZNF474 Gene

mRNA/cDNA for ZNF474 Gene

Unigene Clusters for ZNF474 Gene

Zinc finger protein 474:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF474 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c
SP1: -
SP2: - -
SP3: -

Relevant External Links for ZNF474 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF474 Gene

mRNA expression in normal human tissues for ZNF474 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF474 Gene

This gene is overexpressed in Testis (x23.6).

NURSA nuclear receptor signaling pathways regulating expression of ZNF474 Gene:


SOURCE GeneReport for Unigene cluster for ZNF474 Gene:

genes like me logo Genes that share expression patterns with ZNF474: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF474 Gene

Orthologs for ZNF474 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF474 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC781423 34
  • 82.85 (n)
  • 74.71 (a)
ZNF474 35
  • 46 (a)
(Canis familiaris)
Mammalia LOC474655 34
  • 84.25 (n)
  • 76.52 (a)
ZNF474 35
  • 47 (a)
(Mus musculus)
Mammalia Zfp474 34
  • 77.07 (n)
  • 70.55 (a)
Zfp474 16
Zfp474 35
  • 70 (a)
(Pan troglodytes)
Mammalia ZNF474 34
  • 97.53 (n)
  • 95.33 (a)
ZNF474 35
  • 95 (a)
(Rattus norvegicus)
Mammalia Zfp474 34
  • 76.41 (n)
  • 67.25 (a)
(Monodelphis domestica)
Mammalia ZNF474 35
  • 42 (a)
(Ornithorhynchus anatinus)
Mammalia ZNF474 35
  • 26 (a)
(Anolis carolinensis)
Reptilia ZNF474 35
  • 35 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100494841 34
  • 55.56 (n)
  • 54.3 (a)
(Caenorhabditis elegans)
Secernentea M153.4 34
  • 56.16 (n)
  • 56.52 (a)
M153.4 35
  • 31 (a)
Species where no ortholog for ZNF474 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for ZNF474 Gene

Gene Tree for ZNF474 (if available)
Gene Tree for ZNF474 (if available)

Paralogs for ZNF474 Gene

Paralogs for ZNF474 Gene Pseudogenes for ZNF474 Gene

genes like me logo Genes that share paralogs with ZNF474: view

Variants for ZNF474 Gene

Sequence variations from dbSNP and Humsavar for ZNF474 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
VAR_031146 -
rs754594117 -- 122,127,528(+) ATTTA(C/T)TCACT upstream-variant-2KB
rs775286131 -- 122,127,533(+) CTCAC(G/T)GATAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF474 Gene

Variant ID Type Subtype PubMed ID
esv3425509 CNV insertion 20981092

Variation tolerance for ZNF474 Gene

Residual Variation Intolerance Score: 97.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.53; 88.86% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF474 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF474 Gene

Disorders for ZNF474 Gene

Relevant External Links for ZNF474

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF474 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF474 Gene

Publications for ZNF474 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for ZNF474 Gene

Sources for ZNF474 Gene

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