Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF470 Gene

Aliases for ZNF470 Gene

  • Zinc Finger Protein 470 2 3
  • Chondrogenesis Zinc Finger Protein 1 3 4
  • CZF-1 3 4
  • CZF1 4

External Ids for ZNF470 Gene

Previous GeneCards Identifiers for ZNF470 Gene

  • GC19P061768
  • GC19P057078
  • GC19P053388

Summaries for ZNF470 Gene

GeneCards Summary for ZNF470 Gene

ZNF470 (Zinc Finger Protein 470) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF630.

UniProtKB/Swiss-Prot for ZNF470 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF470 Gene

Genomics for ZNF470 Gene

Regulatory Elements for ZNF470 Gene

Genomic Location for ZNF470 Gene

Start:
56,567,482 bp from pter
End:
56,588,911 bp from pter
Size:
21,430 bases
Orientation:
Plus strand

Genomic View for ZNF470 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF470 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF470 Gene

Proteins for ZNF470 Gene

  • Protein details for ZNF470 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ECI4-ZN470_HUMAN
    Recommended name:
    Zinc finger protein 470
    Protein Accession:
    Q6ECI4
    Secondary Accessions:
    • A8MTW0
    • B9EGU1
    • Q6ZPA1
    • Q9Y2N9

    Protein attributes for ZNF470 Gene

    Size:
    717 amino acids
    Molecular mass:
    82650 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC85218.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF470 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF470 Gene

Proteomics data for ZNF470 Gene at MOPED

Post-translational modifications for ZNF470 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF470 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF470 Gene

Domains for ZNF470 Gene

Gene Families for ZNF470 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF470 Gene

Suggested Antigen Peptide Sequences for ZNF470 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ECI4

UniProtKB/Swiss-Prot:

ZN470_HUMAN :
  • Q6ECI4
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 17 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF470: view

Function for ZNF470 Gene

Molecular function for ZNF470 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF470 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF470: view

Phenotypes for ZNF470 Gene

GenomeRNAi human phenotypes for ZNF470:
genes like me logo Genes that share phenotypes with ZNF470: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF470 Gene

Localization for ZNF470 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF470 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF470 Gene COMPARTMENTS Subcellular localization image for ZNF470 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF470 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with ZNF470: view

Pathways for ZNF470 Gene

SuperPathways for ZNF470 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF470: view

Pathways by source for ZNF470 Gene

2 Reactome pathways for ZNF470 Gene

Interacting Proteins for ZNF470 Gene

Gene Ontology (GO) - Biological Process for ZNF470 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF470: view

Transcripts for ZNF470 Gene

Unigene Clusters for ZNF470 Gene

Zinc finger protein 470:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF470 Gene

No ASD Table

Relevant External Links for ZNF470 Gene

GeneLoc Exon Structure for
ZNF470
ECgene alternative splicing isoforms for
ZNF470

Expression for ZNF470 Gene

mRNA expression in normal human tissues for ZNF470 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF470 Gene

SOURCE GeneReport for Unigene cluster for ZNF470 Gene Hs.204449

mRNA Expression by UniProt/SwissProt for ZNF470 Gene

Q6ECI4-ZN470_HUMAN
Tissue specificity: Highly expressed in testis. Very low expression in thymus. No expression in other tissues tested. Expressed in a differentiation stage-specific manner in mesenchymal chondrogenic progenitor cells.
genes like me logo Genes that share expressions with ZNF470: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ZNF470 Gene

Orthologs for ZNF470 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF470 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF470 35
  • 99.3 (n)
  • 98.95 (a)
dog
(Canis familiaris)
Mammalia ZNF470 35
  • 90.75 (n)
  • 90.66 (a)
ZNF470 36
  • 65 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 48 (a)
OneToMany
Species with no ortholog for ZNF470:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF470 Gene

ENSEMBL:
Gene Tree for ZNF470 (if available)
TreeFam:
Gene Tree for ZNF470 (if available)

Paralogs for ZNF470 Gene

Selected SIMAP similar genes for ZNF470 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF470 Gene

genes like me logo Genes that share paralogs with ZNF470: view

Variants for ZNF470 Gene

Sequence variations from dbSNP and Humsavar for ZNF470 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs11518 -- 56,582,670(-) ggcct(A/C)actct utr-variant-3-prime, intron-variant
rs741252 -- 56,588,853(+) CAATG(C/T)CATGT utr-variant-3-prime
rs759331 -- 56,588,875(+) CCTGC(A/C)GAACT utr-variant-3-prime
rs874104 -- 56,588,912(+) ATAAA(C/T)TACCA downstream-variant-500B
rs995934 -- 56,576,583(+) CTTAT(A/G)TAAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF470 Gene

Variant ID Type Subtype PubMed ID
nsv912518 CNV Gain 21882294

Relevant External Links for ZNF470 Gene

HapMap Linkage Disequilibrium report
ZNF470

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF470 Gene

Disorders for ZNF470 Gene

No disorders were found for ZNF470 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF470 Gene

Publications for ZNF470 Gene

  1. Characterization and chondrocyte differentiation stage-specific expression of KRAB zinc-finger protein gene ZNF470. (PMID: 15302581) Hering T.M. … Johnstone B. (Exp. Cell Res. 2004) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF470 Gene

Sources for ZNF470 Gene

Back to Top

Content