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Aliases for ZNF470 Gene

Aliases for ZNF470 Gene

  • Zinc Finger Protein 470 2 3 5
  • Chondrogenesis Zinc Finger Protein 1 3 4
  • CZF-1 3 4
  • CZF1 4

External Ids for ZNF470 Gene

Previous GeneCards Identifiers for ZNF470 Gene

  • GC19P061768
  • GC19P057078
  • GC19P053388

Summaries for ZNF470 Gene

GeneCards Summary for ZNF470 Gene

ZNF470 (Zinc Finger Protein 470) is a Protein Coding gene. Diseases associated with ZNF470 include Amyotrophic Lateral Sclerosis 1. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF607.

UniProtKB/Swiss-Prot for ZNF470 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF470 Gene

Genomics for ZNF470 Gene

Regulatory Elements for ZNF470 Gene

Enhancers for ZNF470 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF470 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF470 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF470 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF470 Gene

56,567,081 bp from pter
56,588,911 bp from pter
21,831 bases
Plus strand

Genomic View for ZNF470 Gene

Genes around ZNF470 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF470 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF470 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF470 Gene

Proteins for ZNF470 Gene

  • Protein details for ZNF470 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 470
    Protein Accession:
    Secondary Accessions:
    • A8MTW0
    • B9EGU1
    • Q6ZPA1
    • Q9Y2N9

    Protein attributes for ZNF470 Gene

    717 amino acids
    Molecular mass:
    82650 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC85218.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF470 Gene


neXtProt entry for ZNF470 Gene

Proteomics data for ZNF470 Gene at MOPED

Post-translational modifications for ZNF470 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF470 Gene

No data available for DME Specific Peptides for ZNF470 Gene

Domains & Families for ZNF470 Gene

Gene Families for ZNF470 Gene

Protein Domains for ZNF470 Gene

Suggested Antigen Peptide Sequences for ZNF470 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 17 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 17 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF470: view

Function for ZNF470 Gene

Molecular function for ZNF470 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF470 Gene

genes like me logo Genes that share phenotypes with ZNF470: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF470 Gene

Localization for ZNF470 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF470 Gene

Subcellular locations from

Jensen Localization Image for ZNF470 Gene COMPARTMENTS Subcellular localization image for ZNF470 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF470 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with ZNF470: view

Pathways & Interactions for ZNF470 Gene

SuperPathways for ZNF470 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF470: view

Pathways by source for ZNF470 Gene

2 Reactome pathways for ZNF470 Gene

Interacting Proteins for ZNF470 Gene

Gene Ontology (GO) - Biological Process for ZNF470 Gene


No data available for SIGNOR curated interactions for ZNF470 Gene

Drugs & Compounds for ZNF470 Gene

No Compound Related Data Available

Transcripts for ZNF470 Gene

Unigene Clusters for ZNF470 Gene

Zinc finger protein 470:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF470 Gene

No ASD Table

Relevant External Links for ZNF470 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF470 Gene

mRNA expression in normal human tissues for ZNF470 Gene

Protein differential expression in normal tissues from HIPED for ZNF470 Gene

This gene is overexpressed in Lung (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF470 Gene

SOURCE GeneReport for Unigene cluster for ZNF470 Gene Hs.204449

mRNA Expression by UniProt/SwissProt for ZNF470 Gene

Tissue specificity: Highly expressed in testis. Very low expression in thymus. No expression in other tissues tested. Expressed in a differentiation stage-specific manner in mesenchymal chondrogenic progenitor cells.
genes like me logo Genes that share expression patterns with ZNF470: view

Protein tissue co-expression partners for ZNF470 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ZNF470 Gene

Orthologs for ZNF470 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF470 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF470 35
  • 90.75 (n)
  • 90.66 (a)
ZNF470 36
  • 65 (a)
(Pan troglodytes)
Mammalia ZNF470 35
  • 99.3 (n)
  • 98.95 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 48 (a)
Species with no ortholog for ZNF470:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF470 Gene

Gene Tree for ZNF470 (if available)
Gene Tree for ZNF470 (if available)

Paralogs for ZNF470 Gene

(498) SIMAP similar genes for ZNF470 Gene using alignment to 3 proteins: Pseudogenes for ZNF470 Gene

genes like me logo Genes that share paralogs with ZNF470: view

Variants for ZNF470 Gene

Sequence variations from dbSNP and Humsavar for ZNF470 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10421285 - 56,574,400(+) GTTCA(C/G)TGACT reference, missense, utr-variant-5-prime
rs3752179 - 56,577,190(+) AGAGA(A/G)ACCCT reference, missense
rs4801177 - 56,577,682(+) GAGAA(C/T)TCATA reference, missense
rs35077804 - 56,578,354(+) GAGAA(C/T)TCATA intron-variant, reference, missense
rs759331 -- 56,588,875(+) CCTGC(A/C)GAACT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF470 Gene

Variant ID Type Subtype PubMed ID
nsv912518 CNV Gain 21882294

Variation tolerance for ZNF470 Gene

Residual Variation Intolerance Score: 55.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.06; 75.23% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF470 Gene

Disorders for ZNF470 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF470 Gene - From: DISEASES

Disorder Aliases PubMed IDs
amyotrophic lateral sclerosis 1
  • amyotrophic lateral sclerosis
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ZNF470

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ZNF470: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF470 Gene

Publications for ZNF470 Gene

  1. Characterization and chondrocyte differentiation stage-specific expression of KRAB zinc-finger protein gene ZNF470. (PMID: 15302581) Hering T.M. … Johnstone B. (Exp. Cell Res. 2004) 2 3 4 67
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ZNF470 Gene

Sources for ZNF470 Gene