Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ZNF444 Gene

protein-coding   GIFtS: 47
GCID: GC19P056652

Zinc Finger Protein 444

  See ZNF444-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Zinc Finger Protein 4441 2
EZF22 3 5
Endothelial Zinc Finger Protein 22 3
Zinc Finger And SCAN Domain-Containing Protein 172 3
EZF-22 3
ZSCAN172 3

External Ids:    HGNC: 160521   Entrez Gene: 553112   Ensembl: ENSG000001676857   OMIM: 6078745   UniProtKB: Q8N0Y23   

Export aliases for ZNF444 gene to outside databases

Previous GC identifers: GC19P061328 GC19P061344 GC19P052962


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for ZNF444 Gene:
This gene encodes a zinc finger protein which activates transcription of a scavenger receptor gene involved in the
degradation of acetylated low density lipoprotein (Ac-LDL) (PMID: 11978792). This gene is located in a cluster of
zinc finger genes on chromosome 19 at q13.4. A pseudogene of this gene is located on chromosome 15. Multiple
transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Dec 2011)

GeneCards Summary for ZNF444 Gene:
ZNF444 (zinc finger protein 444) is a protein-coding gene. Diseases associated with ZNF444 include epithelial-myoepithelial carcinoma. GO annotations related to this gene include sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is ZKSCAN5.

UniProtKB/Swiss-Prot: ZN444_HUMAN, Q8N0Y2
Function: Transcriptional regulator. Binds to the 5'-flanking critical region of the SCARF1 promoter




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF444 gene promoter:
         E2F-3a   E2F-4   STAT1   E2F-5   E2F-2   Tal-1beta   STAT1alpha   E47   E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF444 promoter sequence
   Search Chromatin IP Primers for ZNF444

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF444


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.43   Ensembl cytogenetic band:  19q13.43   HGNC cytogenetic band: 19q13.43

ZNF444 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF444 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P056652:  view genomic region     (about GC identifiers)

Start:
56,643,968 bp from pter      End:
56,672,262 bp from pter
Size:
28,295 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ZN444_HUMAN, Q8N0Y2 (See protein sequence)
Recommended Name: Zinc finger protein 444  
Size: 327 amino acids; 35204 Da
Sequence caution: Sequence=BAB84889.1; Type=Frameshift; Positions=99;
Secondary accessions: Q8TEQ9 Q8WU35 Q9NUU1
Alternative splicing: 2 isoforms:  Q8N0Y2-1   Q8N0Y2-2   

Explore the universe of human proteins at neXtProt for ZNF444: NX_Q8N0Y2

Explore proteomics data for ZNF444 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF444 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001240721.1  NP_060807.2  

    ENSEMBL proteins: 
     ENSP00000465171   ENSP00000466287   ENSP00000338860   ENSP00000466666   ENSP00000468069  
     ENSP00000465070   ENSP00000465466   ENSP00000468762  

    ZNF444 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ZNF444
    GenScript Custom Purified and Recombinant Proteins Services for ZNF444
    Novus Biologicals ZNF444 Proteins
    Novus Biologicals ZNF444 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZNF444

     
    Search eBioscience for Proteins for ZNF444 

     
    antibodies-online proteins for ZNF444 (3 products) 

     
    antibodies-online peptides for ZNF444

    ZNF444 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZNF444
    Novus Biologicals ZNF444 Antibodies
    Abcam antibodies for ZNF444
    Cloud-Clone Corp. Antibodies for ZNF444
    Search ThermoFisher Antibodies for ZNF444
    antibodies-online antibodies for ZNF444 (10 products) 

    ZNF444 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZNF444
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZNF444
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZNF444
    Cloud-Clone Corp. CLIAs for ZNF444
    Search eBioscience for ELISAs for ZNF444 
    antibodies-online kits for ZNF444 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    Selected InterPro protein domains (see all 6):
     IPR008916 Retrov_capsid_C
     IPR003309 Tscrpt_reg_SCAN
     IPR015880 Znf_C2H2-like
     IPR027775 C2H2_Znf_fam
     IPR013087 Znf_C2H2/integrase_DNA-bd

    Graphical View of Domain Structure for InterPro Entry Q8N0Y2

    ProtoNet protein and cluster: Q8N0Y2

    1 Blocks protein domain: IPB003309 Transcriptional regulator SCAN

    UniProtKB/Swiss-Prot: ZN444_HUMAN, Q8N0Y2
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 4 C2H2-type zinc fingers
    Similarity: Contains 1 SCAN box domain


    Find genes that share domains with ZNF444           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN444_HUMAN, Q8N0Y2
    Function: Transcriptional regulator. Binds to the 5'-flanking critical region of the SCARF1 promoter

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity IBA--
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZNF444           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ZNF444

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat ZNF444 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ZNF444:
    hsa-miR-138
    SwitchGear 3'UTR luciferase reporter plasmidZNF444 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZNF444
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF444

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZNF444

    Clone
    Products:
         
    OriGene clones in human, mouse for ZNF444 (see all 8)
    OriGene ORF clones in mouse, rat for ZNF444
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZNF444 (NM_018337)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF444
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF444

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZNF444
    Browse ESI BIO Cell Lines and PureStem Progenitors for ZNF444 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF444


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    ZN444_HUMAN, Q8N0Y2: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IBA--

    Find genes that share ontologies with ZNF444           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF444
    Interactions:

        Search GeneGlobe Interaction Network for ZNF444

    1 Interacting protein for ZNF444 (Q8N0Y23) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DVL3Q929973I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated ----
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0006357regulation of transcription from RNA polymerase II promoter IBA--
    GO:0006366transcription from RNA polymerase II promoter IBA--

    Find genes that share ontologies with ZNF444           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF444 (ZN444)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ZNF444 gene (2 alternative transcripts): 
    NM_001253792.1  NM_018337.3  

    Unigene Cluster for ZNF444:

    Zinc finger protein 444
    Hs.24545  [show with all ESTs]
    Unigene Representative Sequence: NM_018337
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000587467 ENST00000588358 ENST00000337080(uc002qmn.2 uc002qmm.3)
    ENST00000587195 ENST00000586123 ENST00000587664 ENST00000592949 ENST00000593100
    ENST00000588203 ENST00000591564 ENST00000587236 ENST00000592171
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZNF444 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ZNF444:
    hsa-miR-138
    SwitchGear 3'UTR luciferase reporter plasmidZNF444 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZNF444
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF444
    Clone
    Products:
         
    OriGene clones in human, mouse for ZNF444 (see all 8)
    OriGene ORF clones in mouse, rat for ZNF444
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZNF444 (NM_018337)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF444
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF444
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ZNF444
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF444
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZNF444
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF444
      QuantiFast Probe-based Assays in human, mouse, rat ZNF444

    Additional mRNA sequence: 

    AB052954.1 AB052955.1 AF074985.1 AK001999.1 AK223408.1 AL834130.1 BC021282.2 

    9 DOTS entries:

    DT.209968  DT.95319332  DT.100778630  DT.101958133  DT.99954439  DT.95273876  DT.99968402  DT.92427034 
    DT.95273871 

    Selected AceView cDNA sequences (see all 139):

    BX094029 BM920816 CR590232 CK823295 AI131205 BQ889394 BQ277759 R32522 
    BM980144 AW955650 AI609372 BU618006 CD674794 BM966886 AI573292 AB052954 
    CR597748 BE395510 AB052955 BM451961 AA297241 AL522825 AL834130 CR626120 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZNF444 (see all 15)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d · 7e · 7f · 7g ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a ·
    SP1:                                      -     -     -     -                                                     -     -     -     -     -                     
    SP2:                                      -     -     -     -                                                     -     -     -     -     -                     
    SP3:                                -     -     -     -     -                                                     -                                             
    SP4:                                      -           -     -                                                                                                   
    SP5:                                      -     -     -     -                                               -     -     -     -     -     -                     

    ExUns: 11b · 11c · 11d ^ 12
    SP1:                        
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for ZNF444

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ZNF444 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGATGGACAG
    ZNF444 Expression
    About this image

    ZNF444 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF444 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.24545
        Custom PCR Arrays for ZNF444
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ZNF444
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF444
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZNF444
    QuantiTect SYBR Green Assays in human, mouse, rat ZNF444
    QuantiFast Probe-based Assays in human, mouse, rat ZNF444
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF444

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for ZNF444 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp4441 , 5 zinc finger protein 4441, 5 84.3(n)1
    89.08(a)1
      7 (3.58 cM)5
    726671  NM_001146024.11  NP_001139496.11 
     61722265 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 38)
    Uncharacterized protein
    (see all 38)
    9(a)
    44(a)
    (see all 38)
    many → 1
    many → 1
    (see all 38)
    2(197661483-197686571)
    GL343514.1(204568-205088)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG73686
    l(3)neo386
    lethal (3) neo38
    8(a)
    11(a)
    many ↔ many
    many ↔ many
    3L(11590302-11598474)
    3R(7590760-7604886)


    ENSEMBL Gene Tree for ZNF444 (if available)
    TreeFam Gene Tree for ZNF444 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ZNF444 gene
    ZKSCAN52  
    Selected SIMAP similar genes for ZNF444 using alignment to 7 protein entries:     ZN444_HUMAN (see all proteins) (see all similar genes):
    ZNF167    ZSCAN21    ZKSCAN8    ZSCAN31    ZNF263    ZKSCAN1
    ZNF24    ZKSCAN7    ZNF202    ZNF397    ZNF197    ZNF174
    ZSCAN29    ZNF394    ZSCAN10    ZNF18    LOC100128510    ZNF396

    Find genes that share paralogs with ZNF444           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ZNF444 (see all 556)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1886987001,2
    --56650613(+) AGAGGC/TGAGAG 2 -- us2k10--------
    rs736158001,2
    C,F--56650670(+) TGGTAG/ACCATA 2 -- us2k13Minor allele frequency- A:0.11WA 122
    rs1487167341,2
    --56650701(+) ATTCTC/GCATCT 2 -- us2k10--------
    rs1125728991,2
    C--56650710(+) CTATTC/G/TTGAAG 2 -- us2k11CSA 2
    rs1919290601,2
    --56650736(+) CCTGAC/TGATAG 2 -- us2k10--------
    rs6675231,2
    C,H--56650783(+) tgggcG/Atggtg 2 -- us2k1 tfbs310Minor allele frequency- A:0.19NA WA EA 374
    rs1848429951,2
    --56650794(+) GTTCAC/TGCTTG 2 -- us2k10--------
    rs1422882561,2
    --56650871(+) GCCAAC/TATGGC 2 -- us2k10--------
    rs1901166561,2
    --56650927(+) GTGCAC/TGCCTG 2 -- us2k10--------
    rs48012941,2
    C,F,A,H--56650956(+) aggatG/Tcagca 2 -- us2k113Minor allele frequency- T:0.28NS EA NA WA 788

    HapMap Linkage Disequilibrium report for ZNF444 (56643968 - 56672262 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for ZNF444:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2719020CNV Deletion23290073
    esv2719021CNV Deletion23290073
    dgv586e201CNV Deletion23290073
    esv2719024CNV Deletion23290073
    nsv912513CNV Loss21882294
    dgv207n21CNV Loss19592680
    nsv528361CNV Loss19592680
    dgv206n21CNV Loss19592680
    nsv912516CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF444
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF444

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 607874    OMIM disorders: --

    1 disease for ZNF444:    
    About MalaCards
    epithelial-myoepithelial carcinoma

    2 diseases from the University of Copenhagen DISEASES database for ZNF444:
    Myoepithelial carcinoma     epithelial-myoepithelial carcinoma

    Find genes that share disorders with ZNF444           About GenesLikeMe


    Export disorders for ZNF444 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ZNF444 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ZNF444)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the human gene encoding the scavenger receptor expressed by endothelial cell and its regulation by a novel transcription factor, endothelial zinc finger protein-2. (PubMed id 11978792)1, 2, 3 Adachi H. and Tsujimoto M. (J. Biol. Chem. 2002)
    2. t(19;22)(q13;q12) Translocation leading to the novel fusion gene EWSR1-ZNF444 in soft tissue myoepithelial carcinoma. (PubMed id 19760602)1, 3 Brandal P....Heim S. (amp 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    7. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (Gene 1994)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 55311 HGNC: 16052 AceView: ZNF444 Ensembl:ENSG00000167685 euGenes: HUgn55311
    ECgene: ZNF444 H-InvDB: ZNF444

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ZNF444 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ZNF444 gene:
    Search GeneIP for patents involving ZNF444

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZNF444  
     OriGene qPCR primer pairs and template standards for ZNF444   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ZNF444  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZNF444   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ZNF444   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZNF444   OriGene Custom Protein Services for ZNF444  

     
     
     Block miRNA regulation of human, mouse, rat ZNF444 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ZNF444
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF444 Predesigned siRNA for gene silencing in human, mouse, rat ZNF444
     QuantiFast Probe-based Assays in human, mouse, rat ZNF444 QuantiTect SYBR Green Assays in human, mouse, rat ZNF444
     Custom PCR Arrays for ZNF444 Search Chromatin IP Primers for ZNF444
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZNF444  Search GeneGlobe Interaction Network for ZNF444
     Regulatory tfbs in ZNF444 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ZNF444 GenScript cDNA clones with any tag delivered in your preferred vector for ZNF444
     GenScript Custom Assay Services for ZNF444 GenScript Custom overexpressing Cell Line Services for ZNF444
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ZNF444 (ZN444)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ZNF444 antibodies
     ZNF444 proteins
     ZNF444 lysates
     Antibodies for ZNF444
     See all of Abcam's Antibodies, Kits and Proteins for ZNF444
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for ZNF444
     Antibodies for ZNF444
     ELISAs for ZNF444
     CLIAs for ZNF444



     Browse ESI BIO Cell Lines and PureStem Progenitors for ZNF444
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF444
     SwitchGear 3'UTR luciferase reporter plasmids for ZNF444
     SwitchGear Promoter luciferase reporter plasmids for ZNF444
     Search ThermoFisher Antibodies for ZNF444
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF444
     Browse compounds at ApexBio
     Search Addgene for plasmids for ZNF444
      Search eBioscience for proteins for ZNF444
      Search eBioscience for elisas for ZNF444
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for ZNF444
     antibodies-online antibodies for ZNF444 (10 products)
     antibodies-online kits for ZNF444 (2 products)
     antibodies-online peptides for ZNF444
     antibodies-online proteins for ZNF444 (3 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZNF444 gene at Home site.
    Version: 3.12.252 27 Nov 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4