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Aliases for ZNF442 Gene

Aliases for ZNF442 Gene

  • Zinc Finger Protein 442 2 3

External Ids for ZNF442 Gene

Summaries for ZNF442 Gene

GeneCards Summary for ZNF442 Gene

ZNF442 (Zinc Finger Protein 442) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF709.

UniProtKB/Swiss-Prot for ZNF442 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF442 Gene

Genomics for ZNF442 Gene

Genomic Location for ZNF442 Gene

Start:
12,349,371 bp from pter
End:
12,365,905 bp from pter
Size:
16,535 bases
Orientation:
Minus strand

Genomic View for ZNF442 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF442 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF442 Gene

Regulatory Elements for ZNF442 Gene

Proteins for ZNF442 Gene

  • Protein details for ZNF442 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H7R0-ZN442_HUMAN
    Recommended name:
    Zinc finger protein 442
    Protein Accession:
    Q9H7R0
    Secondary Accessions:
    • B4DJ48

    Protein attributes for ZNF442 Gene

    Size:
    627 amino acids
    Molecular mass:
    72863 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF442 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF442 Gene

Proteomics data for ZNF442 Gene at MOPED

Post-translational modifications for ZNF442 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF442 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF442 Gene

Domains for ZNF442 Gene

Gene Families for ZNF442 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF442 Gene

UniProtKB/Swiss-Prot:

ZN442_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q9H7R0
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9H7R0
Similarity:
  • Contains 16 C2H2-type zinc fingers.:
    • Q9H7R0
genes like me logo Genes that share domains with ZNF442: view

Function for ZNF442 Gene

Molecular function for ZNF442 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF442 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF442: view

miRNA for ZNF442 Gene

miRTarBase miRNAs that target ZNF442

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF442 Gene

Localization for ZNF442 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF442 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF442 Gene COMPARTMENTS Subcellular localization image for ZNF442 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF442 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF442: view

Pathways for ZNF442 Gene

SuperPathways for ZNF442 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF442: view

Pathways by source for ZNF442 Gene

2 Reactome pathways for ZNF442 Gene

Interacting Proteins for ZNF442 Gene

Gene Ontology (GO) - Biological Process for ZNF442 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF442: view

Transcripts for ZNF442 Gene

mRNA/cDNA for ZNF442 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF442 Gene

Zinc finger protein 442:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF442 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b
SP1: - - - -
SP2: - -
SP3:

Relevant External Links for ZNF442 Gene

GeneLoc Exon Structure for
ZNF442
ECgene alternative splicing isoforms for
ZNF442

Expression for ZNF442 Gene

mRNA expression in normal human tissues for ZNF442 Gene

SOURCE GeneReport for Unigene cluster for ZNF442 Gene Hs.253193

genes like me logo Genes that share expressions with ZNF442: view

Orthologs for ZNF442 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF442 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF442 36
  • 98.94 (n)
  • 98.09 (a)
ZNF442 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 50 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm14325 36
  • 63.1 (n)
  • 58.18 (a)
rat
(Rattus norvegicus)
Mammalia LOC100909622 36
  • 64.24 (n)
  • 52.96 (a)
Species with no ortholog for ZNF442:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF442 Gene

ENSEMBL:
Gene Tree for ZNF442 (if available)
TreeFam:
Gene Tree for ZNF442 (if available)

Paralogs for ZNF442 Gene

Selected SIMAP similar genes for ZNF442 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF442 Gene

genes like me logo Genes that share paralogs with ZNF442: view

Variants for ZNF442 Gene

Sequence variations from dbSNP and Humsavar for ZNF442 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs3745654 -- 12,353,270(-) CTGTG(C/T)TGGAG intron-variant
rs3833249 -- 12,365,765(-) TCCCT(-/G)GGGGG upstream-variant-2KB, intron-variant
rs4804178 -- 12,365,394(+) actga(A/G)ggccg intron-variant
rs4804660 -- 12,349,025(+) AAAAT(A/C)CAAAA downstream-variant-500B
rs4804661 -- 12,367,732(+) ggcac(A/G)atctc upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF442 Gene

Variant ID Type Subtype PubMed ID
nsv911068 CNV Gain 21882294
nsv911069 CNV Loss 21882294
esv2718192 CNV Deletion 23290073
nsv911071 CNV Gain 21882294
esv1086965 CNV Deletion 17803354

Relevant External Links for ZNF442 Gene

HapMap Linkage Disequilibrium report
ZNF442

Disorders for ZNF442 Gene

No disorders were found for ZNF442 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF442 Gene

Publications for ZNF442 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4
  5. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjoeblom T. … Velculescu V.E. (Science 2006) 4

Products for ZNF442 Gene

Sources for ZNF442 Gene

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