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Aliases for ZNF44 Gene

Aliases for ZNF44 Gene

  • Zinc Finger Protein 44 2 3
  • Zinc Finger Protein 58 2 3 4
  • Zinc Finger Protein 55 2 3 4
  • KOX7 3 4 6
  • Gonadotropin-Inducible Ovary Transcription Repressor 2 3 4
  • Zinc Finger Protein KOX7 3 4
  • GIOT-2 3 4
  • ZNF55 3 4
  • ZNF58 3 4
  • Gonadotropin Inducible Transcription Repressor-2 3
  • Gonadotropin-Inducible Transcription Repressor 2 3
  • Zinc Finger Protein 44 (KOX 7) 2
  • Zinc Finger Protein ZnFP12 3
  • ZNF504 3
  • GIOT2 4
  • ZNF 3

External Ids for ZNF44 Gene

Previous Symbols for ZNF44 Gene

  • ZNF58
  • ZNF55

Summaries for ZNF44 Gene

GeneCards Summary for ZNF44 Gene

ZNF44 (Zinc Finger Protein 44) is a Protein Coding gene. An important paralog of this gene is ZNF709.

UniProtKB/Swiss-Prot for ZNF44 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF44 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF44 Gene

Genomics for ZNF44 Gene

Genomic Location for ZNF44 Gene

Start:
12,224,686 bp from pter
End:
12,294,899 bp from pter
Size:
70,214 bases
Orientation:
Minus strand

Genomic View for ZNF44 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF44 Gene

Regulatory Elements for ZNF44 Gene

Proteins for ZNF44 Gene

  • Protein details for ZNF44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P15621-ZNF44_HUMAN
    Recommended name:
    Zinc finger protein 44
    Protein Accession:
    P15621
    Secondary Accessions:
    • B4DML9
    • B9EGJ5
    • B9ZVM2
    • P17018
    • Q9ULZ7

    Protein attributes for ZNF44 Gene

    Size:
    663 amino acids
    Molecular mass:
    76524 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAA34357.1; Type=Frameshift; Positions=Several; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF44 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF44 Gene

Proteomics data for ZNF44 Gene at MOPED

Post-translational modifications for ZNF44 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF44 Gene

No data available for DME Specific Peptides for ZNF44 Gene

Domains for ZNF44 Gene

Gene Families for ZNF44 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF44 Gene

UniProtKB/Swiss-Prot:

ZNF44_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • P15621
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • P15621
Similarity:
  • Contains 17 C2H2-type zinc fingers.:
    • P15621
genes like me logo Genes that share domains with ZNF44: view

Function for ZNF44 Gene

Molecular function for ZNF44 Gene

GENATLAS Biochemistry: zinc finger protein 44 (KOX7) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF44: view

miRNA for ZNF44 Gene

miRTarBase miRNAs that target ZNF44

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF44 Gene

Localization for ZNF44 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF44 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF44 Gene COMPARTMENTS Subcellular localization image for ZNF44 gene
Compartment Confidence
cytoskeleton 4
nucleus 4
cytosol 3

Gene Ontology (GO) - Cellular Components for ZNF44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF44: view

Pathways for ZNF44 Gene

SuperPathways for ZNF44 Gene

No Data Available

Interacting Proteins for ZNF44 Gene

Gene Ontology (GO) - Biological Process for ZNF44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF44: view

No data available for Pathways by source for ZNF44 Gene

Compounds for ZNF44 Gene

(1) Novoseek inferred chemical compound relationships for ZNF44 Gene

Compound -log(P) Hits PubMed IDs
zinc 61.8 4
genes like me logo Genes that share compounds with ZNF44: view

Transcripts for ZNF44 Gene

Unigene Clusters for ZNF44 Gene

Zinc finger protein 44:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF44 Gene

No ASD Table

Relevant External Links for ZNF44 Gene

GeneLoc Exon Structure for
ZNF44
ECgene alternative splicing isoforms for
ZNF44

Expression for ZNF44 Gene

mRNA expression in normal human tissues for ZNF44 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF44 Gene

SOURCE GeneReport for Unigene cluster for ZNF44 Gene Hs.296731

genes like me logo Genes that share expressions with ZNF44: view

Orthologs for ZNF44 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF44 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF44 36
  • 99.35 (n)
  • 98.79 (a)
ZNF44 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 49 (a)
ManyToMany
Species with no ortholog for ZNF44:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF44 Gene

ENSEMBL:
Gene Tree for ZNF44 (if available)
TreeFam:
Gene Tree for ZNF44 (if available)

Paralogs for ZNF44 Gene

Selected SIMAP similar genes for ZNF44 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZNF44 Gene

genes like me logo Genes that share paralogs with ZNF44: view

Variants for ZNF44 Gene

Sequence variations from dbSNP and Humsavar for ZNF44 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs382112 -- 12,295,593(+) ggcag(G/T)gcgtg upstream-variant-2KB
rs383725 -- 12,294,211(+) tccca(A/G)gattc intron-variant
rs386901 -- 12,294,737(+) cgtag(C/T)caggg utr-variant-5-prime
rs422563 -- 12,295,203(+) CAGCC(A/G)AGGCC upstream-variant-2KB
rs430267 -- 12,296,194(+) cgggc(C/G)cggtg upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF44 Gene

Variant ID Type Subtype PubMed ID
nsv911068 CNV Gain 21882294
nsv911069 CNV Loss 21882294
nsv833753 CNV Loss 17160897
nsv911070 CNV Gain 21882294
esv2667434 CNV Deletion 23128226
esv2718192 CNV Deletion 23290073

Relevant External Links for ZNF44 Gene

HapMap Linkage Disequilibrium report
ZNF44
Human Gene Mutation Database (HGMD)
ZNF44

Disorders for ZNF44 Gene

No disorders were found for ZNF44 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF44 Gene

Publications for ZNF44 Gene

  1. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PMID: 1505991) Lichter P. … Ward D.C. (Genomics 1992) 2 3
  2. Characterization and mapping of human genes encoding zinc finger proteins. (PMID: 1946370) Bray P.L. … Dawid I.B. (Proc. Natl. Acad. Sci. U.S.A. 1991) 2 3
  3. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4
  4. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF44 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF44
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF44
  • Block miRNA regulation of ZNF44 using miScript Target Protectors

Sources for ZNF44 Gene

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