ZNF439 Gene
protein-coding GIFtS: 46
GCID: GC19P011960
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zinc finger protein 439
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Aliases
for ZNF439 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 4391 2 | | DKFZp571K08371 |
Export aliases for ZNF439 gene to outside databasesPrevious GC identifers: GC19P011804 GC19P011837 GC19P011552 |
Summaries
for ZNF439 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN439_HUMAN, Q8NDP4Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF439 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZNF439
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF439
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF439 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.2 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19p13.13ZNF439 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P011960: view genomic region
(about GC identifiers)
Start:
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11,959,541 bp from pter |
End:
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11,994,565 bp from pter |
Size:
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35,025 bases |
Orientation:
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plus strand |
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Proteins
for ZNF439 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN439_HUMAN, Q8NDP4 (See
protein sequence)Recommended Name: Zinc finger protein 439 Size: 499 amino acids; 58395 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=BAB55187.1; Type=Erroneous initiation;
Secondary accessions: Q8IYZ7 Q96SU1Explore the universe of human proteins at neXtProt for ZNF439: NX_Q8NDP4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NDP4
ZNF439 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_689475.1
ENSEMBL proteins: ENSP00000395632 ENSP00000388234 ENSP00000305077 Reactome Protein details: Q8NDP4
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF439 for ontologies About GeneDecksing
ZNF439 Antibody Products:
Assay Products for ZNF439: |
Protein
Domains /
Families
for ZNF439 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF439 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NDP4ProtoNet protein and cluster: Q8NDP4 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN439_HUMAN, Q8NDP4Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 11 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF439 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN439_HUMAN, Q8NDP4Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF439
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF439
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF439 (NM_152262) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF439 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF439 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF439 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF439 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF439
ZNF439 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF439
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
4 Interacting proteins for ZNF439 (Q8NDP42, 3 ENSP000003050774) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF439 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF439 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF439
Search CenterWatch for drugs/clinical trials and news about ZNF439 / ZN439
|
Transcripts
for ZNF439 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF439 gene: NM_152262.2 Unigene Cluster for ZNF439: Zinc finger protein 439 Hs.528731 [show with all ESTs]Unigene Representative Sequence: AL8339355 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000592495 ENST00000455282(uc002msr.3) ENST00000592534 ENST00000442091
ENST00000304030(uc002mss.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF439
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF439
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF439 (NM_152262) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF439 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF439 |
Additional cDNA sequence: AF024693.1 AK027542.1 AK094739.1 AL833935.1 BC032857.1 13 DOTS entries: DT.100022039 DT.404909 DT.99933309 DT.92414483 DT.97808567 DT.100813705 DT.92028181 DT.95328684 DT.100721204 DT.100751095 DT.101975455 DT.432463 DT.99959058 24/37 AceView cDNA sequences (see all 37): BX090322 BF436917 BU902145 AL833935 BQ061210 NM_152262 N57019 BQ424701 AK027542 BQ012928 AV745689 BE219111 N29327 AA133978 BQ888384 BP335152 AV745540 AW088537 AW206752 BC032857 AW088552 CA336048 BI462675 AW136030
GeneLoc Exon Structure
|
Expression
for ZNF439 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF439 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATTAGATCA
About this image
See ZNF439 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF439
SOURCE GeneReport for Unigene cluster: Hs.528731
SABiosciences Custom PCR Arrays for ZNF439
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF439
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF439 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF439 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF439 |
Orthologs
for ZNF439 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF439 (if available)
TreeFam Gene Tree for ZNF439 (if available) |
Paralogs
for ZNF439 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF439 gene
- ZNF6692 ZNF4902 ZNF5642 ZNF4412 ZNF8782 ENSG000002671792 ZNF142 ENSG000001968262
- ZNF7002 ZNF692 ZNF4402 ZNF4432 ZNF442 ZNF8232 ZNF4912 ENSG000001884742
- ZNF5552 ZNF7092 ZNF6252 ZNF7992 ZNF202 ZNF1012 ZNF7912 ZNF4422
- ZNF4332 ZNF572 ZNF5632 ZNF6272 ENSG000002573552 ZNF1362 ZNF5562 ZNF6702
- ZNF7632 ZNF1242 ZNF6992 ZNF8442 ZNF772
18/434 SIMAP similar genes for ZNF439 using alignment to 2 protein entries: ZN439_HUMAN (see all proteins)
(see all similar genes):ZNF440 ZNF700 ZNF69 ZNF763 ZNF596 MGC12518
ZNF300P1 ZNF738 ZNF235 ZNF625 ZNF844 ZNF224
ZNF846 ZNF195 ZNF721 KRBOX4 ZNF233 ZNF850
ZNF439 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF439 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF439 (11959541 - 11994565 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF439: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF439 |
|
Disorders
/ Diseases
for ZNF439 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF439 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF439 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF439) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF439 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF439 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF439 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF439 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF439 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF439 gene:
Search GeneIP for patents involving ZNF439
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF439 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF439 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF439 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF439 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF439 | | OriGene 3'-UTR Clone for ZNF439 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF439 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF439 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF439 | | OriGene Custom Protein Services for ZNF439 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF439 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF439 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF439 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF439 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF439 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF439 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF439 |
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 | | | ZNF439 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for ZNF439 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF439 |
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