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Aliases for ZNF433 Gene

Aliases for ZNF433 Gene

  • Zinc Finger Protein 433 2 3

External Ids for ZNF433 Gene

Previous GeneCards Identifiers for ZNF433 Gene

  • GC19M011970
  • GC19M011986
  • GC19M011698
  • GC19M012125

Summaries for ZNF433 Gene

GeneCards Summary for ZNF433 Gene

ZNF433 (Zinc Finger Protein 433) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF709.

UniProtKB/Swiss-Prot for ZNF433 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF433 Gene

Genomics for ZNF433 Gene

Regulatory Elements for ZNF433 Gene

Transcription factor binding sites by QIAGEN in the ZNF433 gene promoter:

Genomic Location for ZNF433 Gene

Start:
12,014,717 bp from pter
End:
12,035,741 bp from pter
Size:
21,025 bases
Orientation:
Minus strand

Genomic View for ZNF433 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF433 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF433 Gene

Proteins for ZNF433 Gene

  • Protein details for ZNF433 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N7K0-ZN433_HUMAN
    Recommended name:
    Zinc finger protein 433
    Protein Accession:
    Q8N7K0
    Secondary Accessions:
    • Q86VX3

    Protein attributes for ZNF433 Gene

    Size:
    673 amino acids
    Molecular mass:
    77243 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF433 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF433 Gene

Proteomics data for ZNF433 Gene at MOPED

Post-translational modifications for ZNF433 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF433 Gene

No data available for DME Specific Peptides for ZNF433 Gene

Domains for ZNF433 Gene

Gene Families for ZNF433 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF433 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N7K0

UniProtKB/Swiss-Prot:

ZN433_HUMAN :
  • Q8N7K0
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 19 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF433: view

Function for ZNF433 Gene

Molecular function for ZNF433 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF433 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF433: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF433 Gene

Localization for ZNF433 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF433 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF433 Gene COMPARTMENTS Subcellular localization image for ZNF433 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF433 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF433: view

Pathways for ZNF433 Gene

SuperPathways for ZNF433 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF433: view

Pathways by source for ZNF433 Gene

2 Reactome pathways for ZNF433 Gene

Gene Ontology (GO) - Biological Process for ZNF433 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF433: view

Transcripts for ZNF433 Gene

mRNA/cDNA for ZNF433 Gene

Unigene Clusters for ZNF433 Gene

Zinc finger protein 433:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF433 Gene

No ASD Table

Relevant External Links for ZNF433 Gene

GeneLoc Exon Structure for
ZNF433
ECgene alternative splicing isoforms for
ZNF433

Expression for ZNF433 Gene

mRNA expression in normal human tissues for ZNF433 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF433 Gene

This gene is overexpressed in Testis (6.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF433 Gene

SOURCE GeneReport for Unigene cluster for ZNF433 Gene Hs.667776

genes like me logo Genes that share expressions with ZNF433: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF433 Gene

Orthologs for ZNF433 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF433 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF433 35
  • 99.6 (n)
  • 99.41 (a)
ZNF433 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 51 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia LOC102635315 35
  • 68.22 (n)
  • 61.31 (a)
Species with no ortholog for ZNF433:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF433 Gene

ENSEMBL:
Gene Tree for ZNF433 (if available)
TreeFam:
Gene Tree for ZNF433 (if available)

Paralogs for ZNF433 Gene

Selected SIMAP similar genes for ZNF433 Gene using alignment to 9 proteins:

Pseudogenes.org Pseudogenes for ZNF433 Gene

genes like me logo Genes that share paralogs with ZNF433: view

Variants for ZNF433 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF433 Gene

Variant ID Type Subtype PubMed ID
nsv525966 CNV Gain 19592680
nsv911068 CNV Gain 21882294
nsv911069 CNV Loss 21882294

Relevant External Links for ZNF433 Gene

HapMap Linkage Disequilibrium report
ZNF433

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for ZNF433 Gene

Disorders for ZNF433 Gene

Relevant External Links for ZNF433

Genetic Association Database (GAD)
ZNF433
Human Genome Epidemiology (HuGE) Navigator
ZNF433
genes like me logo Genes that share disorders with ZNF433: view

No data available for UniProtKB/Swiss-Prot for ZNF433 Gene

Publications for ZNF433 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis. (PMID: 20598377) Nischwitz S. … Weber F. (J. Neuroimmunol. 2010) 3 48
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for ZNF433 Gene

  • antibodies-online peptides for ZNF433
  • antibodies-online antibodies for ZNF433
  • antibodies-online kits for ZNF433

Sources for ZNF433 Gene

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