ZNF432 Gene
protein-coding GIFtS: 46
GCID: GC19M052536
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zinc finger protein 432
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Aliases for ZNF432 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 4321 2 | | KIAA07981 3 |
Export aliases for ZNF432 gene to outside databasesPrevious GC identifers: GC19M057172 GC19M057226 GC19M057190 GC19M057216 GC19M052467 |
Summaries for ZNF432 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: ZN432_HUMAN, O94892Function: May be involved in transcriptional regulation
|
Genomic Views for ZNF432 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ZNF432 gene promoter: Nkx3-1 v2 Nkx3-1 Nkx3-1 v4 Nkx3-1 v3 Nkx3-1 v1 Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF432
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF432 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.41 Ensembl cytogenetic band: 19q13.41 HGNC cytogenetic band: 19q13.41ZNF432 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M052536: view genomic region
(about GC identifiers)
Start:
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52,536,361 bp from pter |
End:
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52,552,106 bp from pter |
Size:
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15,746 bases |
Orientation:
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minus strand |
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Proteins for ZNF432 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ZN432_HUMAN, O94892 (See
protein sequence)Recommended Name: Zinc finger protein 432 Size: 652 amino acids; 74836 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=BAA34518.2; Type=Erroneous initiation;Explore the universe of human proteins at neXtProt for ZNF432: NX_O94892
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O94892 ZNF432 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055465.1 ENSEMBL proteins: ENSP00000221315 Reactome Protein details: O94892 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF432 for ontologies About GeneDecksing
ZNF432 Antibody Products: Assay Products for ZNF432: |
Protein
Domains / Families for ZNF432 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF432 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O94892ProtoNet protein and cluster: O94892 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN432_HUMAN, O94892Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 16 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function for ZNF432 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: ZN432_HUMAN, O94892Function: May be involved in transcriptional regulation
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF432 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF432 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF432 (NM_014650) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF432 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF432  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF432 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF432 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZNF432:
|
Pathways & Interactions for ZNF432 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources See GeneCards unified pathways Show all pathways
2
Reactome Pathways for ZNF432
ZNF432 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF432
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF432 for ontologies About GeneDecksing
|
Drugs & Compounds for ZNF432 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for ZNF432 Search CenterWatch for drugs/clinical trials and news about ZNF432 / ZN432 
|
Transcripts for ZNF432 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ZNF432 gene: NM_014650.2 Unigene Cluster for ZNF432: Zinc finger protein 432 Hs.655934 [show with all ESTs]Unigene Representative Sequence: AB0183411 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000221315(uc002pyk.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF432 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF432 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF432 (NM_014650) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF432 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF432  |
Additional cDNA sequence: AB018341.1 AK292827.1 BC002858.2 2 DOTS entries: DT.307847 DT.400726 24/73 AceView cDNA sequences (see all 73): AK093512 NM_014650 AW002711 F28968 AX748176 AK131334 BQ961564 AK131409 AA393349 BC002858 BQ007073 BQ638587 AA827512 BP367484 CB146052 BP377464 AW449479 AI224599 AK129938 AB018341 AF086256 AW250845 BQ286436 BX470424 GeneLoc Exon Structure
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Expression for ZNF432 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF432 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
About this image See ZNF432 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ZNF432
SOURCE GeneReport for Unigene cluster: Hs.655934 SABiosciences Custom PCR Arrays for ZNF432
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF432 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF432 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF432 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF432 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF432 |
Orthologs for ZNF432 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF432 gene from 1/7 species (see all 7) About this table
ENSEMBL Gene Tree for ZNF432 (if available) TreeFam Gene Tree for ZNF432 (if available)  |
Paralogs for ZNF432 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ZNF432 gene
- ZNF1752 ZNF6742 LOC1002875152 ZNF6142 ZNF6132 ZNF262 ZNF3502 ZNF812
- ZNF6492 ZNF6052 ZNF5772 ZNF842 ZNF6302 ZFP372 ZNF4842 ENSG000002296312
- ZNF1822 ZNF412 ZNF2682 LOC1009964642 ZNF6152 ZNF3002
18/425 SIMAP similar genes for ZNF432 using alignment to 5 protein entries: ZN432_HUMAN (see all proteins)
(see all similar genes):DKFZp666M039 ZNF436 ZNF615 PRMD9 ZNF350 PRDM9 HZF36 ZNF146 ZNF589 ZNF613 ZNF614 ZNF323 DKFZp547L155 ZNF16 ZNF32 ZNF497 ZNF664 ZNF844
ZNF432 for paralogs About GeneDecksing
|
Genomic Variants for ZNF432 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 19 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF432 (52536361 - 52552106 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 4 variations for ZNF432 4 CNVs: 8875 3195 34482 53103  | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases for ZNF432 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF432 for disorders About GeneDecksing
2 diseases for ZNF432: About MalaCardspituitary adenoma adenoma Export disorders for ZNF432 gene to outside databases
|
Publications for ZNF432 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF432 gene integrated from 9 sources: (articles sorted by number of sources associating them with ZNF432) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2, 3 Nagase T.... Ohara O. (1998)
- Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry. (PubMed id 16777052)1, 2, 9 Zhan X. and Desiderio D.M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF432 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
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Genome Databases showing ZNF432 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF432 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZNF432 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ZNF432 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF432 gene: Search GeneIP for patents involving ZNF432
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ZNF432 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | Browse OriGene 29mer shRNA kits in GFP-retroviral vector | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF432 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for ZNF432 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF432 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF432 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ZNF432 | | OriGene Custom Protein Services for ZNF432 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF432 | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF432 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF432 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF432 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF432 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF432 |
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| | | Search Tocris compounds for ZNF432 |
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 | | ZNF432 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF432 |
|  |  |  | | | Search ThermoFisher Antibodies for ZNF432 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF432 |
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