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Aliases for ZNF432 Gene

Aliases for ZNF432 Gene

  • Zinc Finger Protein 432 2 3
  • KIAA0798 4

External Ids for ZNF432 Gene

Previous GeneCards Identifiers for ZNF432 Gene

  • GC19M057172
  • GC19M057226
  • GC19M057190
  • GC19M057216
  • GC19M052467
  • GC19M052536

Summaries for ZNF432 Gene

GeneCards Summary for ZNF432 Gene

ZNF432 (Zinc Finger Protein 432) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF169.

UniProtKB/Swiss-Prot for ZNF432 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF432 Gene

Genomics for ZNF432 Gene

Regulatory Elements for ZNF432 Gene

Genomic Location for ZNF432 Gene

Start:
52,031,379 bp from pter
End:
52,095,738 bp from pter
Size:
64,360 bases
Orientation:
Minus strand

Genomic View for ZNF432 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF432 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF432 Gene

Proteins for ZNF432 Gene

  • Protein details for ZNF432 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O94892-ZN432_HUMAN
    Recommended name:
    Zinc finger protein 432
    Protein Accession:
    O94892
    Secondary Accessions:

    Protein attributes for ZNF432 Gene

    Size:
    652 amino acids
    Molecular mass:
    74836 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA34518.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF432 Gene

Proteomics data for ZNF432 Gene at MOPED

Post-translational modifications for ZNF432 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF432 Gene

No data available for DME Specific Peptides for ZNF432 Gene

Domains for ZNF432 Gene

Gene Families for ZNF432 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF432 Gene

Suggested Antigen Peptide Sequences for ZNF432 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O94892

UniProtKB/Swiss-Prot:

ZN432_HUMAN :
  • O94892
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 16 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF432: view

Function for ZNF432 Gene

Molecular function for ZNF432 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF432 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF432: view

Phenotypes for ZNF432 Gene

GenomeRNAi human phenotypes for ZNF432:
genes like me logo Genes that share phenotypes with ZNF432: view

Animal Model Products

CRISPR Products

miRNA for ZNF432 Gene

miRTarBase miRNAs that target ZNF432

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF432

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF432 Gene

Localization for ZNF432 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF432 Gene

Gene Ontology (GO) - Cellular Components for ZNF432 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF432: view

No data available for Subcellular locations from COMPARTMENTS for ZNF432 Gene

Pathways for ZNF432 Gene

SuperPathways for ZNF432 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF432: view

Pathways by source for ZNF432 Gene

2 Reactome pathways for ZNF432 Gene

Interacting Proteins for ZNF432 Gene

Gene Ontology (GO) - Biological Process for ZNF432 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF432: view

Transcripts for ZNF432 Gene

Unigene Clusters for ZNF432 Gene

Zinc finger protein 432:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF432

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF432 Gene

No ASD Table

Relevant External Links for ZNF432 Gene

GeneLoc Exon Structure for
ZNF432
ECgene alternative splicing isoforms for
ZNF432

Expression for ZNF432 Gene

mRNA expression in normal human tissues for ZNF432 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF432 Gene

SOURCE GeneReport for Unigene cluster for ZNF432 Gene Hs.655934

genes like me logo Genes that share expressions with ZNF432: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF432 Gene

Orthologs for ZNF432 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF432 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF432 35
  • 99.54 (n)
  • 99.54 (a)
ZNF432 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF432 35
  • 85.43 (n)
  • 79.45 (a)
dog
(Canis familiaris)
Mammalia ZNF432 35
  • 87.3 (n)
  • 83.87 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 44 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia ZNF432 36
  • 41 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii si:ch211-202h22.10 35
  • 53.58 (n)
  • 48.56 (a)
Species with no ortholog for ZNF432:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF432 Gene

ENSEMBL:
Gene Tree for ZNF432 (if available)
TreeFam:
Gene Tree for ZNF432 (if available)

Paralogs for ZNF432 Gene

Paralogs for ZNF432 Gene

Selected SIMAP similar genes for ZNF432 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF432: view

Variants for ZNF432 Gene

Sequence variations from dbSNP and Humsavar for ZNF432 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs3450 -- 52,049,746(-) ATTGT(A/G)ATTAA upstream-variant-2KB
rs3752118 -- 52,048,233(+) CTCTA(C/G)ACAAA intron-variant
rs3752119 -- 52,048,245(+) GACCA(C/T)CACCC intron-variant
rs3752120 -- 52,048,768(+) TGGGC(C/T)CCTCG utr-variant-5-prime
rs3834981 -- 52,050,503(+) TTACT(-/G)TTGTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF432 Gene

Variant ID Type Subtype PubMed ID
esv638 CNV CNV 17122850
dgv143e55 CNV Gain 17911159
dgv1112e1 CNV Complex 17122850
dgv425n27 CNV Gain 19166990
nsv833872 CNV Loss 17160897

Relevant External Links for ZNF432 Gene

HapMap Linkage Disequilibrium report
ZNF432

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF432 Gene

Disorders for ZNF432 Gene

Relevant External Links for ZNF432

Genetic Association Database (GAD)
ZNF432
genes like me logo Genes that share disorders with ZNF432: view

No data available for UniProtKB/Swiss-Prot for ZNF432 Gene

Publications for ZNF432 Gene

  1. Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry. (PMID: 16777052) Zhan X. … Desiderio D.M. (Anal. Biochem. 2006) 3 4 23
  2. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 9872452) Nagase T. … Ohara O. (DNA Res. 1998) 2 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics. (PMID: 24280104) Wu A.C. … Tantisira K. (J. Allergy Clin. Immunol. 2014) 3
  5. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. (PMID: 17068223) Duerr R.H. … Cho J.H. (Science 2006) 48

Products for ZNF432 Gene

Sources for ZNF432 Gene

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