External Ids for ZNF431 Gene
Previous GeneCards Identifiers for ZNF431 Gene
GeneCards Summary for ZNF431 Gene
ZNF431 (Zinc Finger Protein 431) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and core promoter sequence-specific DNA binding. An important paralog of this gene is ZNF253.
UniProtKB/Swiss-Prot for ZNF431 Gene
Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5-GCGCCC-3 in the promoter of PTCH1 (By similarity).