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Aliases for ZNF430 Gene

Aliases for ZNF430 Gene

  • Zinc Finger Protein 430 2 3

External Ids for ZNF430 Gene

Summaries for ZNF430 Gene

GeneCards Summary for ZNF430 Gene

ZNF430 (Zinc Finger Protein 430) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF430 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF430 Gene

Genomics for ZNF430 Gene

Genomic Location for ZNF430 Gene

Start:
21,020,620 bp from pter
End:
21,060,050 bp from pter
Size:
39,431 bases
Orientation:
Plus strand

Genomic View for ZNF430 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF430 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF430 Gene

Regulatory Elements for ZNF430 Gene

Proteins for ZNF430 Gene

  • Protein details for ZNF430 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H8G1-ZN430_HUMAN
    Recommended name:
    Zinc finger protein 430
    Protein Accession:
    Q9H8G1
    Secondary Accessions:
    • Q86V70

    Protein attributes for ZNF430 Gene

    Size:
    570 amino acids
    Molecular mass:
    66319 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14656.1; Type=Frameshift; Positions=293; Evidence={ECO:0000305};

neXtProt entry for ZNF430 Gene

Proteomics data for ZNF430 Gene at MOPED

Post-translational modifications for ZNF430 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys188 and Lys464

Other Protein References for ZNF430 Gene

No data available for DME Specific Peptides for ZNF430 Gene

Domains for ZNF430 Gene

Gene Families for ZNF430 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF430 Gene

Suggested Antigen Peptide Sequences for ZNF430 Gene

Graphical View of Domain Structure for InterPro Entry

Q9H8G1

UniProtKB/Swiss-Prot:

ZN430_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q9H8G1
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9H8G1
Similarity:
  • Contains 12 C2H2-type zinc fingers.:
    • Q9H8G1
genes like me logo Genes that share domains with ZNF430: view

Function for ZNF430 Gene

Molecular function for ZNF430 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF430 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF430: view

miRNA for ZNF430 Gene

miRTarBase miRNAs that target ZNF430

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF430 Gene

Localization for ZNF430 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF430 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF430 Gene COMPARTMENTS Subcellular localization image for ZNF430 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF430 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF430: view

Pathways for ZNF430 Gene

SuperPathways for ZNF430 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF430: view

Pathways by source for ZNF430 Gene

2 Reactome pathways for ZNF430 Gene

Interacting Proteins for ZNF430 Gene

Gene Ontology (GO) - Biological Process for ZNF430 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0021762 substantia nigra development IEP 22926577
genes like me logo Genes that share ontologies with ZNF430: view

Transcripts for ZNF430 Gene

Unigene Clusters for ZNF430 Gene

Zinc finger protein 430:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF430 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b
SP1:
SP2:
SP3: - - -

Relevant External Links for ZNF430 Gene

GeneLoc Exon Structure for
ZNF430
ECgene alternative splicing isoforms for
ZNF430

Expression for ZNF430 Gene

mRNA expression in normal human tissues for ZNF430 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF430 Gene

SOURCE GeneReport for Unigene cluster for ZNF430 Gene Hs.729202

genes like me logo Genes that share expressions with ZNF430: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF430 Gene

Orthologs for ZNF430 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF430 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF430 35
  • 99.04 (n)
  • 98.38 (a)
ZNF430 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 53 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 38 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp874b 36
  • 49 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 37 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 52 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
Species with no ortholog for ZNF430:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF430 Gene

ENSEMBL:
Gene Tree for ZNF430 (if available)
TreeFam:
Gene Tree for ZNF430 (if available)

Paralogs for ZNF430 Gene

Selected SIMAP similar genes for ZNF430 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZNF430: view

Variants for ZNF430 Gene

Sequence variations from dbSNP and Humsavar for ZNF430 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1054703 -- 21,059,859(+) AAGAT(A/G)CATGA utr-variant-3-prime
rs1470020 -- 21,034,405(+) TTGCT(A/G)TCAGA intron-variant
rs1866384 -- 21,025,273(+) aaagt(A/C)atttt intron-variant
rs1971815 -- 21,050,007(+) CCTCC(C/T)GAGTA intron-variant
rs2081050 -- 21,028,867(-) CTTTA(C/T)TAAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF430 Gene

Variant ID Type Subtype PubMed ID
nsv458377 CNV Gain 19166990
nsv911411 CNV Loss 21882294
nsv2439 CNV Insertion 18451855
esv1634993 CNV Deletion 17803354
nsv911412 CNV Loss 21882294

Relevant External Links for ZNF430 Gene

HapMap Linkage Disequilibrium report
ZNF430

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF430 Gene

Disorders for ZNF430 Gene

No disorders were found for ZNF430 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF430 Gene

Publications for ZNF430 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  4. A whole genome screen for HIV restriction factors. (PMID: 22082156) Liu L. … McKnight A. (Retrovirology 2011) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for ZNF430 Gene

Sources for ZNF430 Gene

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