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Aliases for ZNF430 Gene

Aliases for ZNF430 Gene

  • Zinc Finger Protein 430 2 3 5

External Ids for ZNF430 Gene

Previous GeneCards Identifiers for ZNF430 Gene

  • GC19P020979
  • GC19P021203
  • GC19P020694

Summaries for ZNF430 Gene

GeneCards Summary for ZNF430 Gene

ZNF430 (Zinc Finger Protein 430) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF718.

UniProtKB/Swiss-Prot for ZNF430 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF430 Gene

Genomics for ZNF430 Gene

Regulatory Elements for ZNF430 Gene

Enhancers for ZNF430 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF430 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF430 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF430 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF430 Gene

21,020,620 bp from pter
21,060,055 bp from pter
39,436 bases
Plus strand

Genomic View for ZNF430 Gene

Genes around ZNF430 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF430 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF430 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF430 Gene

Proteins for ZNF430 Gene

  • Protein details for ZNF430 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 430
    Protein Accession:
    Secondary Accessions:
    • Q86V70

    Protein attributes for ZNF430 Gene

    570 amino acids
    Molecular mass:
    66319 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB14656.1; Type=Frameshift; Positions=293; Evidence={ECO:0000305};

neXtProt entry for ZNF430 Gene

Proteomics data for ZNF430 Gene at MOPED

Post-translational modifications for ZNF430 Gene

  • Ubiquitination at Lys 188
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF430 Gene

No data available for DME Specific Peptides for ZNF430 Gene

Domains & Families for ZNF430 Gene

Gene Families for ZNF430 Gene

Protein Domains for ZNF430 Gene

Suggested Antigen Peptide Sequences for ZNF430 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF430: view

Function for ZNF430 Gene

Molecular function for ZNF430 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF430: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF430 Gene

Localization for ZNF430 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF430 Gene

Subcellular locations from

Jensen Localization Image for ZNF430 Gene COMPARTMENTS Subcellular localization image for ZNF430 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF430 Gene

Pathways & Interactions for ZNF430 Gene

SuperPathways for ZNF430 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF430: view

Pathways by source for ZNF430 Gene

2 Reactome pathways for ZNF430 Gene

Interacting Proteins for ZNF430 Gene

Gene Ontology (GO) - Biological Process for ZNF430 Gene


No data available for SIGNOR curated interactions for ZNF430 Gene

Drugs & Compounds for ZNF430 Gene

No Compound Related Data Available

Transcripts for ZNF430 Gene

Unigene Clusters for ZNF430 Gene

Zinc finger protein 430:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF430 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b
SP3: - - -

Relevant External Links for ZNF430 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF430 Gene

mRNA expression in normal human tissues for ZNF430 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF430 Gene

SOURCE GeneReport for Unigene cluster for ZNF430 Gene Hs.729202

genes like me logo Genes that share expression patterns with ZNF430: view

Protein tissue co-expression partners for ZNF430 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF430 Gene

Orthologs for ZNF430 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF430 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF430 35
  • 99.04 (n)
  • 98.38 (a)
ZNF430 36
  • 98 (a)
(Bos Taurus)
Mammalia -- 36
  • 53 (a)
(Canis familiaris)
Mammalia -- 36
  • 38 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 37 (a)
-- 36
  • 50 (a)
(Mus musculus)
Mammalia Zfp874b 36
  • 49 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 52 (a)
-- 36
  • 33 (a)
-- 36
  • 39 (a)
-- 36
  • 39 (a)
-- 36
  • 31 (a)
-- 36
  • 31 (a)
-- 36
  • 30 (a)
-- 36
  • 29 (a)
Species with no ortholog for ZNF430:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF430 Gene

Gene Tree for ZNF430 (if available)
Gene Tree for ZNF430 (if available)

Paralogs for ZNF430 Gene

(533) SIMAP similar genes for ZNF430 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZNF430: view

Variants for ZNF430 Gene

Sequence variations from dbSNP and Humsavar for ZNF430 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7256437 -- 21,056,918(+) AGAAG(C/T)CTTTC reference, missense
rs12975789 -- 21,045,701(+) ggagt(C/T)tgttt intron-variant
rs7507514 -- 21,049,657(+) GTTAC(A/G)TTTCC intron-variant
rs12978053 -- 21,042,603(+) ctaac(A/G)cggtg intron-variant
rs12978381 -- 21,042,748(+) gcgcc(A/C)ctgca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF430 Gene

Variant ID Type Subtype PubMed ID
nsv458377 CNV Gain 19166990
nsv911411 CNV Loss 21882294
nsv2439 CNV Insertion 18451855
esv1634993 CNV Deletion 17803354
nsv911412 CNV Loss 21882294

Variation tolerance for ZNF430 Gene

Residual Variation Intolerance Score: 77.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.37; 27.09% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF430 Gene

Disorders for ZNF430 Gene

Relevant External Links for ZNF430

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF430 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF430 Gene

Publications for ZNF430 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosis. (PMID: 22926577) Chen S. … Liu F. (Neurochem. Res. 2012) 3
  4. A whole genome screen for HIV restriction factors. (PMID: 22082156) Liu L. … McKnight A. (Retrovirology 2011) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF430 Gene

Sources for ZNF430 Gene