ZNF429 Gene
protein-coding GIFtS: 44
GCID: GC19P021688
|
|
zinc finger protein 429
| |
Aliases
for ZNF429 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 4291 2 |
Export aliases for ZNF429 gene to outside databasesPrevious GC identifers: GC19U900125 GC19P021480 GC19P021178 |
Summaries
for ZNF429 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN429_HUMAN, Q86V71Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF429 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZNF429
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF429
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF429 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.1 Ensembl cytogenetic band: 19p12 HGNC cytogenetic band: 19p13.1ZNF429 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P021688: view genomic region
(about GC identifiers)
Start:
|
21,688,437 bp from pter |
End:
|
21,721,079 bp from pter |
Size:
|
32,643 bases |
Orientation:
|
plus strand |
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Proteins
for ZNF429 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN429_HUMAN, Q86V71 (See
protein sequence)Recommended Name: Zinc finger protein 429 Size: 674 amino acids; 78152 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=AAK01422.1; Type=Frameshift; Positions=Several; Sequence=AAK01422.1; Type=Miscellaneousdiscrepancy; Sequence=AAP30884.1; Type=Frameshift; Positions=Several; Sequence=AAP30884.1; Type=Miscellaneousdiscrepancy;
Secondary accessions: A6NLV7 Q9BZE6Explore the universe of human proteins at neXtProt for ZNF429: NX_Q86V71
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86V71
ZNF429 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001001415.2
ENSEMBL proteins: ENSP00000351280 Reactome Protein details: Q86V71
Human Recombinant Protein Products for ZNF429:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF429 for ontologies About GeneDecksing
ZNF429 Antibody Products:
Assay Products for ZNF429: |
Protein
Domains /
Families
for ZNF429 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF429 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86V71ProtoNet protein and cluster: Q86V71 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN429_HUMAN, Q86V71Similarity: Contains 18 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF429 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZN429_HUMAN, Q86V71Function: May be involved in transcriptional regulation Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF429 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for ZNF429:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF429
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF429
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF429 (NM_001001415) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF429 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF429 |
|
Pathways & Interactions
for ZNF429 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF429
ZNF429 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF429
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF429 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF429 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF429
Search CenterWatch for drugs/clinical trials and news about ZNF429 / ZN429
|
Transcripts
for ZNF429 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF429 gene: NM_001001415.2 Unigene Clusters for ZNF429: Zinc finger protein 429 Hs.572567 , Hs.709598 [show with all ESTs]Unigene Representative Sequences: AK057495, NM_0010014151 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000358491(uc002nqd.1 uc010ecu.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF429
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF429
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF429 (NM_001001415) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF429 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF429 |
Additional cDNA sequence: AF325191.1 AK308708.1 AY269786.1 5 DOTS entries: DT.40236894 DT.91678125 DT.95150089 DT.91849541 DT.95081594 24/40 AceView cDNA sequences (see all 40): AI433770 BF445865 BQ188254 AI360347 BE550243 BG742323 AI610519 AK097381 BQ219868 AW865549 AW865337 BQ225738 N83176 BU790163 AI216833 BC040866 BU790460 BU145721 BM996292 BX102125 BG547934 BI915693 AL596889 BX537835
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF429 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | - | | | | - | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | - | | | | - | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF429
|
Expression
for ZNF429 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF429 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGAATGTGG
About this image
See ZNF429 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene clusters: Hs.572567 Hs.709598
SABiosciences Custom PCR Arrays for ZNF429
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF429
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF429 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF429 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF429 |
Orthologs
for ZNF429 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF429 gene from 1/4 species (see all 4) About this table
ENSEMBL Gene Tree for ZNF429 (if available)
TreeFam Gene Tree for ZNF429 (if available) |
Paralogs
for ZNF429 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF429 gene
- ZNF852 ZNF4932 ZNF4862 ZNF1002 ZNF922 ZNF7322 ZNF1382 ZNF6752
- ZNF5062 ZNF2732 ZNF66P2 ZNF6952 ZNF6262 ZNF6802 ZNF2532 ZNF4792
- ZNF932 ZNF4922 ZNF6822 ZNF6762 ZNF1412 ZNF6812 ZNF6792 ZNF2572
- ZNF2542 ZNF7372 ZNF724P2 ZNF982 ZNF849P2 ZNF7162 ZNF7142 ZNF4302
- ZNF7302 ZNF6782 ZNF1172 ZNF7082 ZNF1072 ZNF4312 ZNF902
18/509 SIMAP similar genes for ZNF429 using alignment to 3 protein entries: ZN429_HUMAN (see all proteins)
(see all similar genes):ZNF78L1 MGC12518 BIRC5 ZNF273 OK/SW-cl.18 ZNF738
ZNF506 ZNF254 ZNF431 ZNF708 ZNF724P ZNF730
ZNF737 ZNF818P ZFS-4 ZNF100 ZNF232 ZNF257
ZNF429 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF429 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF429 (21688437 - 21721079 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ZNF429
2 CNVs: 9303 5094
1 Indel: 61681 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF429 |
|
Disorders
/ Diseases
for ZNF429 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF429 for disorders About MalaCards
ZNF429 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: ZNF429 (1 document)
Export disorders for ZNF429 gene to outside databases
|
Publications
for ZNF429 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF429 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF429) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937. (PubMed id 7865130)1, 2 Abrink M.... Hellman L. (1995)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Genome-wide association study of acute post-surgical pain in humans. (PubMed id 19207018)1 Kim H....Dionne R.A. (2009)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
|
External Searches for ZNF429 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF429 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF429 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF429 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF429 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF429 gene:
Search GeneIP for patents involving ZNF429
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF429 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF429 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF429 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF429 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF429 | | OriGene 3'-UTR Clone for ZNF429 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF429 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF429 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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