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Aliases for ZNF428 Gene

Aliases for ZNF428 Gene

  • Zinc Finger Protein 428 2 3
  • Enzyme-Like Protein PIT13 3 4
  • C19orf37 3 4
  • Chromosome 19 Open Reading Frame 37 2
  • Zfp428 3

External Ids for ZNF428 Gene

Previous Symbols for ZNF428 Gene

  • C19orf37

Summaries for ZNF428 Gene

GeneCards Summary for ZNF428 Gene

ZNF428 (Zinc Finger Protein 428) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF428 Gene

Genomics for ZNF428 Gene

Genomic Location for ZNF428 Gene

Start:
43,607,219 bp from pter
End:
43,620,146 bp from pter
Size:
12,928 bases
Orientation:
Minus strand

Genomic View for ZNF428 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF428 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF428 Gene

Regulatory Elements for ZNF428 Gene

Proteins for ZNF428 Gene

  • Protein details for ZNF428 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96B54-ZN428_HUMAN
    Recommended name:
    Zinc finger protein 428
    Protein Accession:
    Q96B54
    Secondary Accessions:
    • O95054
    • Q6X3Y3

    Protein attributes for ZNF428 Gene

    Size:
    188 amino acids
    Molecular mass:
    20481 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC99795.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAP87382.1; Type=Miscellaneous discrepancy; Note=Intron retention at the C-terminus.; Evidence={ECO:0000305};

neXtProt entry for ZNF428 Gene

Proteomics data for ZNF428 Gene at MOPED

Post-translational modifications for ZNF428 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF428 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF428 Gene

Domains for ZNF428 Gene

Gene Families for ZNF428 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF428 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

ZN428_HUMAN
Similarity:
  • Contains 1 C2H2-type zinc finger.:
    • Q96B54
genes like me logo Genes that share domains with ZNF428: view

Function for ZNF428 Gene

Gene Ontology (GO) - Molecular Function for ZNF428 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF428: view

miRNA for ZNF428 Gene

miRTarBase miRNAs that target ZNF428

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF428 Gene

Localization for ZNF428 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF428 Gene COMPARTMENTS Subcellular localization image for ZNF428 gene
Compartment Confidence
nucleus 3

No data available for Gene Ontology (GO) - Cellular Components for ZNF428 Gene

Pathways for ZNF428 Gene

SuperPathways for ZNF428 Gene

No Data Available

Interacting Proteins for ZNF428 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000300811%0d%0a9606.ENSP00000310275%0d%0a9606.ENSP00000358081%0d%0a
Selected Interacting proteins: ENSP00000300811 Q96B54-ZN428_HUMAN for ZNF428 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for ZNF428 Gene

None

No data available for Pathways by source for ZNF428 Gene

Transcripts for ZNF428 Gene

mRNA/cDNA for ZNF428 Gene

Unigene Clusters for ZNF428 Gene

Zinc finger protein 428:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF428 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4
SP1: - -
SP2: -
SP3:

Relevant External Links for ZNF428 Gene

GeneLoc Exon Structure for
ZNF428
ECgene alternative splicing isoforms for
ZNF428

Expression for ZNF428 Gene

mRNA expression in normal human tissues for ZNF428 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF428 Gene

SOURCE GeneReport for Unigene cluster for ZNF428 Gene Hs.99093

genes like me logo Genes that share expressions with ZNF428: view

Orthologs for ZNF428 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF428 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF428 36
  • 99.65 (n)
  • 100 (a)
ZNF428 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF428 36
  • 85.99 (n)
  • 87.23 (a)
ZNF428 37
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF428 36
  • 87.94 (n)
  • 88.3 (a)
ZNF428 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp428 36
  • 83.43 (n)
  • 87.28 (a)
Zfp428 16
Zfp428 37
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF428 37
  • 69 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp428 36
  • 82.95 (n)
  • 87.36 (a)
Species with no ortholog for ZNF428:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF428 Gene

ENSEMBL:
Gene Tree for ZNF428 (if available)
TreeFam:
Gene Tree for ZNF428 (if available)

Paralogs for ZNF428 Gene

Selected SIMAP similar genes for ZNF428 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF428: view

No data available for Paralogs for ZNF428 Gene

Variants for ZNF428 Gene

Sequence variations from dbSNP and Humsavar for ZNF428 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs3046 -- 43,620,583(-) TATAG(A/G)ACCAT upstream-variant-2KB
rs304722 -- 43,609,394(+) TAAAA(C/T)ATTTA intron-variant
rs365063 -- 43,609,862(+) ACCAC(A/G)GTGTG intron-variant
rs367652 -- 43,609,246(+) GCTGA(A/C)CCTGG intron-variant
rs368745 -- 43,620,216(+) CTGGC(G/T)GATTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF428 Gene

Variant ID Type Subtype PubMed ID
nsv833839 CNV Loss 17160897

Relevant External Links for ZNF428 Gene

HapMap Linkage Disequilibrium report
ZNF428

Disorders for ZNF428 Gene

No disorders were found for ZNF428 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF428 Gene

Publications for ZNF428 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  3. Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners. (PMID: 19759913) Montes de Oca R. … Wilson K.L. (PLoS ONE 2009) 3
  4. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PMID: 22990118) Woods N.T. … Monteiro A.N. (Sci Signal 2012) 3
  5. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PMID: 23824909) Chen Y. … Ge F. (Mol. Cell Proteomics 2013) 3

Products for ZNF428 Gene

Sources for ZNF428 Gene

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