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Aliases for ZNF428 Gene

Aliases for ZNF428 Gene

  • Zinc Finger Protein 428 2 3
  • Enzyme-Like Protein PIT13 3 4
  • C19orf37 3 4
  • Chromosome 19 Open Reading Frame 37 2
  • Zfp428 3

External Ids for ZNF428 Gene

Previous HGNC Symbols for ZNF428 Gene

  • C19orf37

Previous GeneCards Identifiers for ZNF428 Gene

  • GC19M048805
  • GC19M044112
  • GC19M040542
  • GC19M044115

Summaries for ZNF428 Gene

GeneCards Summary for ZNF428 Gene

ZNF428 (Zinc Finger Protein 428) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF428 Gene

Genomics for ZNF428 Gene

Regulatory Elements for ZNF428 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF428 Gene

43,607,219 bp from pter
43,619,874 bp from pter
12,656 bases
Minus strand

Genomic View for ZNF428 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF428 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF428 Gene

Proteins for ZNF428 Gene

  • Protein details for ZNF428 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 428
    Protein Accession:
    Secondary Accessions:
    • O95054
    • Q6X3Y3

    Protein attributes for ZNF428 Gene

    188 amino acids
    Molecular mass:
    20481 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAC99795.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAP87382.1; Type=Miscellaneous discrepancy; Note=Intron retention at the C-terminus.; Evidence={ECO:0000305};

neXtProt entry for ZNF428 Gene

Proteomics data for ZNF428 Gene at MOPED

Post-translational modifications for ZNF428 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF428 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF428 Gene

Domains & Families for ZNF428 Gene

Gene Families for ZNF428 Gene

Protein Domains for ZNF428 Gene


Suggested Antigen Peptide Sequences for ZNF428 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 C2H2-type zinc finger.
  • Contains 1 C2H2-type zinc finger.
genes like me logo Genes that share domains with ZNF428: view

Function for ZNF428 Gene

Gene Ontology (GO) - Molecular Function for ZNF428 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF428: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF428

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF428 Gene

Localization for ZNF428 Gene

Subcellular locations from

Jensen Localization Image for ZNF428 Gene COMPARTMENTS Subcellular localization image for ZNF428 gene
Compartment Confidence
mitochondrion 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZNF428 Gene

Pathways & Interactions for ZNF428 Gene

SuperPathways for ZNF428 Gene

No Data Available

Interacting Proteins for ZNF428 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: Q96B54-ZN428_HUMAN ENSP00000300811 for ZNF428 Gene via I2D STRING

Gene Ontology (GO) - Biological Process for ZNF428 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZNF428 Gene

Drugs & Compounds for ZNF428 Gene

No Compound Related Data Available

Transcripts for ZNF428 Gene

mRNA/cDNA for ZNF428 Gene

Unigene Clusters for ZNF428 Gene

Zinc finger protein 428:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF428

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF428 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4
SP1: - -
SP2: -

Relevant External Links for ZNF428 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF428 Gene

mRNA expression in normal human tissues for ZNF428 Gene

Protein differential expression in normal tissues from HIPED for ZNF428 Gene

This gene is overexpressed in Adrenal (45.5) and Fetal Brain (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF428 Gene

SOURCE GeneReport for Unigene cluster for ZNF428 Gene Hs.99093

genes like me logo Genes that share expression patterns with ZNF428: view

Protein tissue co-expression partners for ZNF428 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF428 Gene

Orthologs for ZNF428 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF428 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF428 35
  • 85.99 (n)
  • 87.23 (a)
ZNF428 36
  • 91 (a)
(Canis familiaris)
Mammalia ZNF428 35
  • 87.94 (n)
  • 88.3 (a)
ZNF428 36
  • 94 (a)
(Mus musculus)
Mammalia Zfp428 35
  • 83.43 (n)
  • 87.28 (a)
Zfp428 16
Zfp428 36
  • 90 (a)
(Pan troglodytes)
Mammalia ZNF428 35
  • 99.65 (n)
  • 100 (a)
ZNF428 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Zfp428 35
  • 82.95 (n)
  • 87.36 (a)
(Monodelphis domestica)
Mammalia ZNF428 36
  • 69 (a)
Species with no ortholog for ZNF428:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF428 Gene

Gene Tree for ZNF428 (if available)
Gene Tree for ZNF428 (if available)

Paralogs for ZNF428 Gene

(1) SIMAP similar genes for ZNF428 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF428: view

No data available for Paralogs for ZNF428 Gene

Variants for ZNF428 Gene

Sequence variations from dbSNP and Humsavar for ZNF428 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs304722 -- 43,609,394(+) TAAAA(C/T)ATTTA intron-variant
rs365063 -- 43,609,862(+) ACCAC(A/G)GTGTG intron-variant
rs367652 -- 43,609,246(+) GCTGA(A/C)CCTGG intron-variant
rs758871 -- 43,607,602(+) TCCCC(A/G)TATGG utr-variant-3-prime
rs2005852 -- 43,607,411(+) cgggc(C/G)ggaat utr-variant-3-prime, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZNF428 Gene

Variant ID Type Subtype PubMed ID
nsv833839 CNV Loss 17160897

Variation tolerance for ZNF428 Gene

Residual Variation Intolerance Score: 72.17% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.28; 40.90% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF428 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF428 Gene

Disorders for ZNF428 Gene

Relevant External Links for ZNF428

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ZNF428: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF428 Gene

Publications for ZNF428 Gene

  1. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PMID: 23824909) Chen Y. … Ge F. (Mol. Cell Proteomics 2013) 67
  2. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PMID: 22990118) Woods N.T. … Monteiro A.N. (Sci Signal 2012) 67
  3. Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners. (PMID: 19759913) Montes de Oca R. … Wilson K.L. (PLoS ONE 2009) 67
  4. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for ZNF428 Gene

Sources for ZNF428 Gene

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