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Aliases for ZNF426 Gene

Aliases for ZNF426 Gene

  • Zinc Finger Protein 426 2 3

External Ids for ZNF426 Gene

Previous GeneCards Identifiers for ZNF426 Gene

  • GC19M009861
  • GC19M009483
  • GC19M009499
  • GC19M009638
  • GC19M009219

Summaries for ZNF426 Gene

GeneCards Summary for ZNF426 Gene

ZNF426 (Zinc Finger Protein 426) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF559.

UniProtKB/Swiss-Prot for ZNF426 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF426 Gene

Genomics for ZNF426 Gene

Regulatory Elements for ZNF426 Gene

Transcription factor binding sites by QIAGEN in the ZNF426 gene promoter:

Genomic Location for ZNF426 Gene

Start:
9,527,991 bp from pter
End:
9,538,958 bp from pter
Size:
10,968 bases
Orientation:
Minus strand

Genomic View for ZNF426 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF426 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF426 Gene

Proteins for ZNF426 Gene

  • Protein details for ZNF426 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BUY5-ZN426_HUMAN
    Recommended name:
    Zinc finger protein 426
    Protein Accession:
    Q9BUY5
    Secondary Accessions:
    • B3KTL2

    Protein attributes for ZNF426 Gene

    Size:
    554 amino acids
    Molecular mass:
    63106 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF426 Gene

Proteomics data for ZNF426 Gene at MOPED

Post-translational modifications for ZNF426 Gene

  • Ubiquitination at Lys204
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF426 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF426 Gene

Domains for ZNF426 Gene

Gene Families for ZNF426 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF426 Gene

Suggested Antigen Peptide Sequences for ZNF426 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BUY5

UniProtKB/Swiss-Prot:

ZN426_HUMAN :
  • Q9BUY5
Domain:
  • Contains 1 KRAB domain.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF426: view

Function for ZNF426 Gene

Molecular function for ZNF426 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF426 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF426: view

Animal Model Products

CRISPR Products

miRNA for ZNF426 Gene

miRTarBase miRNAs that target ZNF426

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF426

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF426 Gene

Localization for ZNF426 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF426 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF426 Gene COMPARTMENTS Subcellular localization image for ZNF426 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF426 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF426: view

Pathways for ZNF426 Gene

SuperPathways for ZNF426 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF426: view

Pathways by source for ZNF426 Gene

2 Reactome pathways for ZNF426 Gene

Gene Ontology (GO) - Biological Process for ZNF426 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF426: view

Transcripts for ZNF426 Gene

Unigene Clusters for ZNF426 Gene

Zinc finger protein 426:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF426

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF426 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b
SP1: -
SP2:

Relevant External Links for ZNF426 Gene

GeneLoc Exon Structure for
ZNF426
ECgene alternative splicing isoforms for
ZNF426

Expression for ZNF426 Gene

mRNA expression in normal human tissues for ZNF426 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF426 Gene

This gene is overexpressed in Esophagus - Mucosa (4.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF426 Gene

SOURCE GeneReport for Unigene cluster for ZNF426 Gene Hs.594011

genes like me logo Genes that share expressions with ZNF426: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF426 Gene

Orthologs for ZNF426 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF426 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF426 35
  • 99.52 (n)
  • 99.1 (a)
ZNF426 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 34 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 52 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp426 35
  • 81.29 (n)
  • 74.41 (a)
Zfp426 16
Zfp426 36
  • 73 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp426 35
  • 80.87 (n)
  • 75.23 (a)
Species with no ortholog for ZNF426:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF426 Gene

ENSEMBL:
Gene Tree for ZNF426 (if available)
TreeFam:
Gene Tree for ZNF426 (if available)

Paralogs for ZNF426 Gene

Paralogs for ZNF426 Gene

Selected SIMAP similar genes for ZNF426 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF426 Gene

genes like me logo Genes that share paralogs with ZNF426: view

Variants for ZNF426 Gene

Sequence variations from dbSNP and Humsavar for ZNF426 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs733101 -- 9,535,965(-) CCTTA(C/T)GTGTG intron-variant
rs733102 -- 9,535,910(-) ATCAC(A/G)TTTAG intron-variant
rs733103 -- 9,535,864(-) TTTGC(A/G)TTTTC intron-variant
rs888870 -- 9,535,461(+) ggtgg(A/G)aggat intron-variant
rs888871 -- 9,535,623(+) AGTTC(A/G)AGACT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF426 Gene

Variant ID Type Subtype PubMed ID
nsv911020 CNV Gain 21882294
nsv911024 CNV Loss 21882294

Relevant External Links for ZNF426 Gene

HapMap Linkage Disequilibrium report
ZNF426
Human Gene Mutation Database (HGMD)
ZNF426

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF426 Gene

Disorders for ZNF426 Gene

No disorders were found for ZNF426 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF426 Gene

Publications for ZNF426 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. The transcriptional repressor K-RBP modulates RTA-mediated transactivation and lytic replication of Kaposi's sarcoma-associated herpesvirus. (PMID: 17409159) Yang Z. … Wood C. (J. Virol. 2007) 3
  5. Kaposi's sarcoma-associated herpesvirus transactivator RTA promotes degradation of the repressors to regulate viral lytic replication. (PMID: 18216089) Yang Z. … Wood C. (J. Virol. 2008) 3

Products for ZNF426 Gene

Sources for ZNF426 Gene

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