External Ids for ZNF420 Gene
Previous GeneCards Identifiers for ZNF420 Gene
The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016]
GeneCards Summary for ZNF420 Gene
ZNF420 (Zinc Finger Protein 420) is a Protein Coding gene. Among its related pathways are TP53 Regulates Transcription of Cell Death Genes and Regulation of TP53 Activity. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF546.
UniProtKB/Swiss-Prot for ZNF420 Gene
May be involved in transcriptional regulation.