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ZNF420 Gene

protein-coding   GIFtS: 50
GCID: GC19P037498

Zinc Finger Protein 420

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 4201 2
APAK2
ATM And P53-Associated KZNF Protein2

External Ids:    HGNC: 206491   Entrez Gene: 1479232   Ensembl: ENSG000001970507   UniProtKB: Q8TAQ53   

Export aliases for ZNF420 gene to outside databases

Previous GC identifers: GC00U900995 GC19P042262 GC19P037569 GC19P034038


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZNF420 Gene:
ZNF420 (zinc finger protein 420) is a protein-coding gene. An important paralog of this gene is ZNF334.

UniProtKB/Swiss-Prot: ZN420_HUMAN, Q8TAQ5
Function: May be involved in transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF420 gene promoter:
         STAT1   GCNF-1   GCNF   Msx-1   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF420 promoter sequence
   Search Chromatin IP Primers for ZNF420

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF420


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.12   Ensembl cytogenetic band:  19q13.12   HGNC cytogenetic band: 19q13.12

ZNF420 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF420 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P037498:  view genomic region     (about GC identifiers)

Start:
37,498,759 bp from pter      End:
37,621,216 bp from pter
Size:
122,458 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ZN420_HUMAN, Q8TAQ5 (See protein sequence)
Recommended Name: Zinc finger protein 420  
Size: 688 amino acids; 80247 Da
Secondary accessions: B2RDY6

Explore the universe of human proteins at neXtProt for ZNF420: NX_Q8TAQ5

Explore proteomics data for ZNF420 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF420 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_653290.2  
    ENSEMBL proteins: 
     ENSP00000468387   ENSP00000466057   ENSP00000465346   ENSP00000467369   ENSP00000306102  
     ENSP00000467772   ENSP00000338770   ENSP00000468736  
    Reactome Protein details: Q8TAQ5

    ZNF420 Human Recombinant Protein Products:

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    Novus Biologicals ZNF420 Lysate
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZNF420

     
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    antibodies-online peptides for ZNF420

    ZNF420 Antibody Products:

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    antibodies-online antibodies for ZNF420 (26 products) 

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    Cloud-Clone Corp. ELISAs for ZNF420
    Cloud-Clone Corp. CLIAs for ZNF420
    Search eBioscience for ELISAs for ZNF420 
    antibodies-online kits for ZNF420 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    4 InterPro protein domains:
     IPR001909 Krueppel-associated_box
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q8TAQ5

    ProtoNet protein and cluster: Q8TAQ5

    2 Blocks protein domains:
    IPB001909 KRAB box
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZN420_HUMAN, Q8TAQ5
    Similarity: Contains 19 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain


    Find genes that share domains with ZNF420           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN420_HUMAN, Q8TAQ5
    Function: May be involved in transcriptional regulation

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IBA--
    GO:0005515protein binding IPI--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZNF420           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ZNF420:
     Decreased viability of wild-ty 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ZNF420

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZNF420:
    hsa-mir-124-3p (MIRT023175), hsa-mir-92a-3p (MIRT049236), hsa-mir-423-3p (MIRT042504)

    Block miRNA regulation of human, mouse, rat ZNF420 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate ZNF420:
    hsa-miR-23b hsa-miR-130a* hsa-miR-23a hsa-miR-23c hsa-miR-342-3p
    SwitchGear 3'UTR luciferase reporter plasmidZNF420 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZNF420
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF420

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: ZNF420 (NM_144689)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF420

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF420


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN420_HUMAN, Q8TAQ5: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    Find genes that share ontologies with ZNF420           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZNF420 About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40


    Find genes that share SuperPaths with ZNF420           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZNF420
        Generic Transcription Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF420
    Interactions:

        Search GeneGlobe Interaction Network for ZNF420

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for ZNF420 (Q8TAQ51, 2, 3 ENSP000003387704) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TP53P046371, 2, 3, ENSP000002693054EBI-3923307,EBI-366083 MINT-7989670 MINT-7989584 MINT-7989724 MINT-7989773 I2D: score=2 STRING: ENSP00000269305
    CDKN2AQ8N726-11EBI-3923307,EBI-8169299 MINT-7989705 MINT-7989653 MINT-7989686 MINT-7989603 MINT-7989635 MINT-7989724 MINT-7989747 MINT-7989626
    S100A4ENSP000003462944STRING: ENSP00000346294
    CDK2AP1ENSP000002616924STRING: ENSP00000261692
    CYP4V2ENSP000003680794STRING: ENSP00000368079
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IBA--

    Find genes that share ontologies with ZNF420           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF420 (ZN420)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZNF420 gene: 
    NM_144689.3  

    Unigene Cluster for ZNF420:

    Zinc finger protein 420
    Hs.444992  [show with all ESTs]
    Unigene Representative Sequence: BC026210
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000590332 ENST00000587029 ENST00000589461 ENST00000587082 ENST00000304239
    ENST00000589245 ENST00000337995(uc002ofl.3) ENST00000585862 ENST00000586540

    miRNA
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    Block miRNA regulation of human, mouse, rat ZNF420 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate ZNF420:
    hsa-miR-23b hsa-miR-130a* hsa-miR-23a hsa-miR-23c hsa-miR-342-3p
    SwitchGear 3'UTR luciferase reporter plasmidZNF420 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZNF420
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF420
    Clone
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    OriGene clones in human, mouse for ZNF420 (see all 6)
    OriGene ORF clones in mouse, rat for ZNF420
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZNF420 (NM_144689)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF420
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF420
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ZNF420
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF420
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ZNF420
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF420
      QuantiFast Probe-based Assays in human, mouse, rat ZNF420

    Additional mRNA sequence: 

    AK056695.1 AK056753.1 AK315728.1 BC026210.2 

    5 DOTS entries:

    DT.108762  DT.121446766  DT.121446981  DT.121446952  DT.121447000 

    Selected AceView cDNA sequences (see all 56):

    NM_144689 BU176809 BQ949663 BM053059 AI339586 BQ188303 BM052765 AW591586 
    AW316546 AI273684 AI138668 AI479265 AI281171 AK056753 BC026210 AI281179 
    AL710909 BM693388 AA976476 AA934732 BM557617 AK056695 BG109748 AA453441 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF420    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8
    SP1:                    -     -                                       
    SP2:                    -     -                                       
    SP3:              -     -     -                                       
    SP4:                                                                  


    ECgene alternative splicing isoforms for ZNF420

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF420 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGCAGAAAT
    ZNF420 Expression
    About this image


    ZNF420 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
    ZNF420 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF420 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.444992
        Custom PCR Arrays for ZNF420
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF420

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for ZNF420 gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp4201 , 5 zinc finger protein 4201, 5 85.18(n)1
    90.83(a)1
      7 (17.26 cM)5
    2330581  NM_172740.21  NP_766328.21 
     298599795 


    ENSEMBL Gene Tree for ZNF420 (if available)
    TreeFam Gene Tree for ZNF420 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF420 gene
    ZNF3342  ZNF780A2  ZNF6652  ZNF72  ZNF232  ZNF33A2  RBAK2  ZNF7172  
    ZNF302  ZNF5732  ZNF33B2  ZNF5402  ZNF2512  ZNF6052  ZNF842  ZNF1892  
    ZNF5712  ZNF6302  ZNF3372  ZNF2832  ZNF4042  ZNF1352  ZNF4842  ZNF122  
    ZNF3452  ZNF1842  ZNF6992  ZNF412  ZNF6152  ZNF4702  ZNF5692  
    Selected SIMAP similar genes for ZNF420 using alignment to 8 protein entries:     ZN420_HUMAN (see all proteins) (see all similar genes):
    smap-7    ZNF850    ZFP57    ZNF738    FIK    MGC12518
    ZNF705B    ZNF705F    ZNF818P    ZNF93    MRPS17    ZNF81
    KRBOX4    ZNF78L1    ZNF208    ZNF614    ZNF616    ZNF675

    Find genes that share paralogs with ZNF420           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for ZNF420
    PGOHUM00000234153 PGOHUM00000258068


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZNF420 (see all 1076)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1910411271,2
    --37567479(+) GTCCAA/GGTGTT 1 -- us2k10--------
    rs1832763731,2
    --37567587(+) ATGTCC/TCTATA 1 -- us2k10--------
    rs1877210041,2
    C--37567610(+) TCATCC/TTTTTT 1 -- us2k10--------
    rs1165964271,2
    F--37567959(+) TTTTCC/GCTCTG 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1140893681,2
    F--37568027(+) TTATTC/TAAAAA 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1926510821,2
    --37568163(+) ACCTAA/GAATTT 1 -- us2k10--------
    rs1177556001,2
    F--37568261(+) CAACCG/ATACCC 1 -- us2k11Minor allele frequency- A:0.01NA 120
    rs1832273251,2
    --37568272(+) AGTAAA/TAAGAG 1 -- us2k10--------
    rs1882353091,2
    --37568414(+) GGATTC/TTTCCC 1 -- us2k10--------
    rs1395586071,2
    --37568443(+) TCCAAA/TAGAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZNF420 (37498759 - 37621216 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ZNF420:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv2477CNV Loss18451855
    nsv833818CNV Gain17160897
    dgv3856n71CNV Gain21882294

    Human Gene Mutation Database (HGMD): ZNF420
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF420
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF420

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ZNF420           About GenesLikeMe


    Export disorders for ZNF420 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF420 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ZNF420)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Apak competes with p53 for direct binding to intron 1 of p53AIP1 to regulate apoptosis. (PubMed id 22334068)1 Yuan L....Zhang L. (EMBO Rep. 2012)
    4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    5. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    6. ARF-dependent regulation of ATM and p53 associated KZNF (Apak) protein activity in response to oncogenic stress. (PubMed id 20713054)1 Wang S....Zhang L. (FEBS Lett. 2010)
    7. Differential regulation of Apak by various DNA damage signals. (PubMed id 19629643)1 Wang S....Chen H. (Mol. Cell. Biochem. 2010)
    8. KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis. (PubMed id 19377469)1 Tian C....He F. (Nat. Cell Biol. 2009)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin. (PubMed id 11157984)1 Govind S.... Ahmed S. (J. Cell Biol. 2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 147923 HGNC: 20649 AceView: FLJ32191 Ensembl:ENSG00000197050 euGenes: HUgn147923
    ECgene: ZNF420 H-InvDB: ZNF420

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZNF420 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZNF420 gene:
    Search GeneIP for patents involving ZNF420

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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