ZNF417 Gene
protein-coding GIFtS: 45
GCID: GC19M058417
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zinc finger protein 417
| |
Aliases
for ZNF417 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 4171 2 | | MGC340791 |
Export aliases for ZNF417 gene to outside databasesPrevious GC identifers: GC00U900990 GC19M063111 GC19M054728 |
Summaries
for ZNF417 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN417_HUMAN, Q8TAU3Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF417 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZNF417
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF417
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF417 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.43 Ensembl cytogenetic band: 19q13.43 HGNC cytogenetic band: 19q13.43ZNF417 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M058417: view genomic region
(about GC identifiers)
Start:
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58,417,142 bp from pter |
End:
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58,427,978 bp from pter |
Size:
|
10,837 bases |
Orientation:
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minus strand |
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Proteins
for ZNF417 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN417_HUMAN, Q8TAU3 (See
protein sequence)Recommended Name: Zinc finger protein 417 Size: 575 amino acids; 65733 Da
Subcellular location: Nucleus (Probable)Explore the universe of human proteins at neXtProt for ZNF417: NX_Q8TAU3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TAU3
ZNF417 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_689688.2
ENSEMBL proteins: ENSP00000311319 ENSP00000442760 Reactome Protein details: Q8TAU3
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF417 for ontologies About GeneDecksing
ZNF417 Antibody Products:
Assay Products for ZNF417: |
Protein
Domains /
Families
for ZNF417 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF417 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8TAU3ProtoNet protein and cluster: Q8TAU3 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN417_HUMAN, Q8TAU3Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 13 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF417 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN417_HUMAN, Q8TAU3Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF417
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF417 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF417 (NM_152475) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF417 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF417 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF417 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF417 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF417 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF417
ZNF417 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF417
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/15 Interacting proteins for ZNF417 (Q8TAU32, 3 ENSP000003113194) via UniProtKB, MINT, STRING, and/or I2D (see all 15)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| CCDC85B | Q158342, 3, ENSP000003116954 | MINT-66598 I2D:
score=4 STRING: ENSP00000311695 | | CEP72 | Q9P2092, 3, ENSP000002649354 | MINT-67447 I2D:
score=4 STRING: ENSP00000264935 | | TRIM37 | O949722, 3, ENSP000002622944 | MINT-67756 I2D:
score=4 STRING: ENSP00000262294 | | BEGAIN | Q9BUH82, 3, ENSP000003473014 | MINT-66995 I2D:
score=4 STRING: ENSP00000347301 | | KRTAP4-12 | Q9BQ662, 3, ENSP000003775824 | MINT-67219 I2D:
score=4 STRING: ENSP00000377582 |
About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF417 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF417 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF417
Search CenterWatch for drugs/clinical trials and news about ZNF417 / ZN417
|
Transcripts
for ZNF417 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF417 gene: NM_152475.2 Unigene Cluster for ZNF417: Zinc finger protein 417 Hs.567710 [show with all ESTs]Unigene Representative Sequence: NM_1524752 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000312026(uc002qqq.3 uc010yhm.2 uc002qqr.3) ENST00000536263
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF417
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF417 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF417 (NM_152475) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF417 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF417 |
Additional cDNA sequence: AK293789.1 BC025783.1 BC103757.1 14 DOTS entries: DT.86849824 DT.97862743 DT.100773928 DT.205752 DT.306335 DT.91653802 DT.100040721 DT.100773927 DT.100773929 DT.100773930 DT.101978126 DT.121503780 DT.121503889 DT.91749895 24/120 AceView cDNA sequences (see all 120): AI271888 BI822651 BM273143 BI760856 BI833232 CN482664 BM987016 AY695825 BQ613755 AI150545 BF926933 CK820062 C21240 AK022663 CK820063 AV704447 AK096401 AB075836 BQ711860 NM_133460 AI669095 AI150398 BM512320 BX119887
GeneLoc Exon Structure
|
Expression
for ZNF417 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF417 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ZNF417 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF417
SOURCE GeneReport for Unigene cluster: Hs.567710
SABiosciences Custom PCR Arrays for ZNF417
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF417
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF417 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF417 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF417 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF417 |
Orthologs
for ZNF417 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF417 (if available)
TreeFam Gene Tree for ZNF417 (if available) |
Paralogs
for ZNF417 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF417 gene
- ZNF587 ZNF5492 ZNF2112 ZNF7922 ZNF7492 ZNF5512 ZNF7762 ZNF5472
- ZNF172 ZNF4162 ZNF5482 ZNF3042 ZNF587B2 ZNF7732 ZNF1322 ZIK12
- ZNF6712 ZNF1342 ZNF4182 ZNF2562 ZNF1542 ZNF5522 ZNF7722 ZNF5302
- ZNF4192
18/513 SIMAP similar genes for ZNF417 using alignment to 8 protein entries: ZN417_HUMAN (see all proteins)
(see all similar genes):ZNF587 ZNF78L1 HZF36 kr-znf3 DKFZp313M0722 FLJ00301
ZNF323 ZNF418 ZNF818P ZSCAN31 ZNF146 ZNF774
ZNF696 ZNF22 ZNF32 ZNF697 ZNF DKFZp666M039
ZNF417 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF417 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF417 (58417142 - 58427978 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF417: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF417 |
|
Disorders
/ Diseases
for ZNF417 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF417 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF417 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF417) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF417 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF417 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF417 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF417 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF417 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF417 gene:
Search GeneIP for patents involving ZNF417
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF417 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF417 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF417 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF417 | | | OriGene Protein Over-expression Lysate for ZNF417 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF417 | | OriGene 3'-UTR Clone for ZNF417 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF417 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF417 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF417 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF417 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF417 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF417 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF417 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF417 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF417 |
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 | | | ZNF417 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF417 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF417 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF417 |
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