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Aliases for ZNF417 Gene

Aliases for ZNF417 Gene

  • Zinc Finger Protein 417 2 3

External Ids for ZNF417 Gene

Previous GeneCards Identifiers for ZNF417 Gene

  • GC00U900990
  • GC19M063111
  • GC19M058417
  • GC19M054728

Summaries for ZNF417 Gene

GeneCards Summary for ZNF417 Gene

ZNF417 (Zinc Finger Protein 417) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF417 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF417 Gene

Genomics for ZNF417 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF417 Gene

Chromosome:
19
Start:
57,900,296 bp from pter
End:
57,916,616 bp from pter
Size:
16,321 bases
Orientation:
Minus strand

Genomic View for ZNF417 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for ZNF417 Gene

No data available for Regulatory Elements for ZNF417 Gene

Proteins for ZNF417 Gene

  • Protein details for ZNF417 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TAU3-ZN417_HUMAN
    Recommended name:
    Zinc finger protein 417
    Protein Accession:
    Q8TAU3
    Secondary Accessions:
    • B4DEU1

    Protein attributes for ZNF417 Gene

    Size:
    575 amino acids
    Molecular mass:
    65733 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF417 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF417 Gene

Proteomics data for ZNF417 Gene at MOPED

Post-translational modifications for ZNF417 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for ZNF417 Gene

Domains & Families for ZNF417 Gene

Gene Families for ZNF417 Gene

Protein Domains for ZNF417 Gene

Suggested Antigen Peptide Sequences for ZNF417 Gene

Graphical View of Domain Structure for InterPro Entry

Q8TAU3

UniProtKB/Swiss-Prot:

ZN417_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF417: view

Function for ZNF417 Gene

Molecular function for ZNF417 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF417 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF417: view

Phenotypes for ZNF417 Gene

GenomeRNAi human phenotypes for ZNF417:
genes like me logo Genes that share phenotypes with ZNF417: view

Animal Model Products

CRISPR Products

miRNA for ZNF417 Gene

miRTarBase miRNAs that target ZNF417

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF417

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF417 Gene

Localization for ZNF417 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF417 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF417 Gene COMPARTMENTS Subcellular localization image for ZNF417 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF417 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF417: view

Pathways & Interactions for ZNF417 Gene

SuperPathways for ZNF417 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF417: view

Pathways by source for ZNF417 Gene

2 Reactome pathways for ZNF417 Gene

Gene Ontology (GO) - Biological Process for ZNF417 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF417: view

No data available for SIGNOR curated interactions for ZNF417 Gene

Drugs & Compounds for ZNF417 Gene

No Compound Related Data Available

Transcripts for ZNF417 Gene

Unigene Clusters for ZNF417 Gene

Zinc finger protein 417:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF417

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF417 Gene

No ASD Table

Relevant External Links for ZNF417 Gene

GeneLoc Exon Structure for
ZNF417
ECgene alternative splicing isoforms for
ZNF417

Expression for ZNF417 Gene

mRNA expression in normal human tissues for ZNF417 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF417 Gene



SOURCE GeneReport for Unigene cluster for ZNF417 Gene Hs.567710

genes like me logo Genes that share expression patterns with ZNF417: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF417 Gene

Orthologs for ZNF417 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF417 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 36
  • 52 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 96 (a)
ManyToMany
-- 36
  • 98 (a)
ManyToMany
Species with no ortholog for ZNF417:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF417 Gene

ENSEMBL:
Gene Tree for ZNF417 (if available)
TreeFam:
Gene Tree for ZNF417 (if available)

Paralogs for ZNF417 Gene

(535) SIMAP similar genes for ZNF417 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with ZNF417: view

Variants for ZNF417 Gene

Sequence variations from dbSNP and Humsavar for ZNF417 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs453043 -- 57,917,269(-) CCTTG(A/C/T)GCTCC upstream-variant-2KB
rs2042906 -- 57,914,670(-) ACCTT(C/G)GTGCA intron-variant, missense, reference
rs3745133 -- 57,909,331(-) TCAGC(A/C/G/T)TGTTC missense, reference
rs3826671 -- 57,909,760(-) CTTCC(A/G)CGAGT missense, reference
rs6510112 -- 57,906,058(+) TTTCC(A/G)AGGAA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF417 Gene

Variant ID Type Subtype PubMed ID
esv2719094 CNV Deletion 23290073

Variation tolerance for ZNF417 Gene

Residual Variation Intolerance Score: 90.62% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.69; 66.02% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF417 Gene

HapMap Linkage Disequilibrium report
ZNF417

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF417 Gene

Disorders for ZNF417 Gene

Relevant External Links for ZNF417

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF417
genes like me logo Genes that share disorders with ZNF417: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF417 Gene

Publications for ZNF417 Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  2. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 67
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 67

Products for ZNF417 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF417
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF417
  • Block miRNA regulation of ZNF417 using miScript Target Protectors

Sources for ZNF417 Gene

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