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Aliases for ZNF416 Gene

Aliases for ZNF416 Gene

  • Zinc Finger Protein 416 2 3 5

External Ids for ZNF416 Gene

Previous GeneCards Identifiers for ZNF416 Gene

  • GC00U900989
  • GC19M062775
  • GC19M058082
  • GC19M054395

Summaries for ZNF416 Gene

GeneCards Summary for ZNF416 Gene

ZNF416 (Zinc Finger Protein 416) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF416 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF416 Gene

Genomics for ZNF416 Gene

Regulatory Elements for ZNF416 Gene

Enhancers for ZNF416 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF416 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF416 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF416 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF416 Gene

Chromosome:
19
Start:
57,571,010 bp from pter
End:
57,579,180 bp from pter
Size:
8,171 bases
Orientation:
Minus strand

Genomic View for ZNF416 Gene

Genes around ZNF416 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF416 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF416 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF416 Gene

Proteins for ZNF416 Gene

  • Protein details for ZNF416 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BWM5-ZN416_HUMAN
    Recommended name:
    Zinc finger protein 416
    Protein Accession:
    Q9BWM5
    Secondary Accessions:
    • Q9NWW8

    Protein attributes for ZNF416 Gene

    Size:
    594 amino acids
    Molecular mass:
    67188 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA91257.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};

neXtProt entry for ZNF416 Gene

Proteomics data for ZNF416 Gene at MOPED

Post-translational modifications for ZNF416 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF416 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ZNF416 Gene

Domains & Families for ZNF416 Gene

Gene Families for ZNF416 Gene

Protein Domains for ZNF416 Gene

Suggested Antigen Peptide Sequences for ZNF416 Gene

Graphical View of Domain Structure for InterPro Entry

Q9BWM5

UniProtKB/Swiss-Prot:

ZN416_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF416: view

Function for ZNF416 Gene

Molecular function for ZNF416 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF416: view

Animal Model Products

CRISPR Products

miRNA for ZNF416 Gene

Targeted motifs for ZNF416 Gene
HOMER Transcription Factor Regulatory Elements motif ZNF416
  • Consensus sequence: WDNCTGGGCA Submotif: canonical Cell Type: HEK293 GEO ID: GSE58341

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models and Transcription Factor Targets for ZNF416 Gene

Localization for ZNF416 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF416 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF416 Gene COMPARTMENTS Subcellular localization image for ZNF416 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF416 Gene

Pathways & Interactions for ZNF416 Gene

SuperPathways for ZNF416 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF416: view

Pathways by source for ZNF416 Gene

2 Reactome pathways for ZNF416 Gene

Interacting Proteins for ZNF416 Gene

Gene Ontology (GO) - Biological Process for ZNF416 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF416: view

No data available for SIGNOR curated interactions for ZNF416 Gene

Drugs & Compounds for ZNF416 Gene

No Compound Related Data Available

Transcripts for ZNF416 Gene

mRNA/cDNA for ZNF416 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(33) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF416 Gene

Zinc finger protein 416:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF416 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b
SP1:
SP2: -

Relevant External Links for ZNF416 Gene

GeneLoc Exon Structure for
ZNF416
ECgene alternative splicing isoforms for
ZNF416

Expression for ZNF416 Gene

mRNA expression in normal human tissues for ZNF416 Gene

Protein differential expression in normal tissues from HIPED for ZNF416 Gene

This gene is overexpressed in Platelet (51.8) and Peripheral blood mononuclear cells (17.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF416 Gene



SOURCE GeneReport for Unigene cluster for ZNF416 Gene Hs.247711

genes like me logo Genes that share expression patterns with ZNF416: view

Protein tissue co-expression partners for ZNF416 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF416 Gene

Orthologs for ZNF416 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF416 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF416 35
  • 76.33 (n)
  • 62.79 (a)
-- 36
  • 59 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp418 35
  • 68.3 (n)
  • 55.45 (a)
Zfp418 16
Zfp418 36
  • 46 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia ZNF416 35
  • 99.66 (n)
  • 99.66 (a)
ZNF416 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp418 35
  • 68.4 (n)
  • 54.76 (a)
Species with no ortholog for ZNF416:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF416 Gene

ENSEMBL:
Gene Tree for ZNF416 (if available)
TreeFam:
Gene Tree for ZNF416 (if available)

Paralogs for ZNF416 Gene

(484) SIMAP similar genes for ZNF416 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF416: view

Variants for ZNF416 Gene

Sequence variations from dbSNP and Humsavar for ZNF416 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7259128 -- 57,580,927(+) ATAAG(A/G)CATAG upstream-variant-2KB
rs12977037 -- 57,574,828(+) TATTC(A/G)GGCCC intron-variant
rs886265 -- 57,578,153(+) CATGG(C/G)CTGAT intron-variant
rs140090288 -- 57,575,910(+) GCCAC(A/G)TCCTC intron-variant, reference, synonymous-codon
rs140151340 -- 57,573,412(+) TCATG(A/C/G)AACAG reference, synonymous-codon, missense

Variation tolerance for ZNF416 Gene

Residual Variation Intolerance Score: 40.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.27; 25.29% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for ZNF416 Gene

Disorders for ZNF416 Gene

Relevant External Links for ZNF416

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF416

No disorders were found for ZNF416 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF416 Gene

Publications for ZNF416 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF416 Gene

Sources for ZNF416 Gene

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