Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF415 Gene

Aliases for ZNF415 Gene

  • Zinc Finger Protein 415 2 3

External Ids for ZNF415 Gene

Previous GeneCards Identifiers for ZNF415 Gene

  • GC19M058287
  • GC19M058302
  • GC19M053611
  • GC19M049935

Summaries for ZNF415 Gene

GeneCards Summary for ZNF415 Gene

ZNF415 (Zinc Finger Protein 415) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF415 Gene

  • Involved in transcriptional regulation. Transcriptional activity differed among the various isoforms. All isoforms except isoform 3 seem to suppresses the transcriptional activities of AP-1 and p53/TP53.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF415 Gene

Genomics for ZNF415 Gene

Regulatory Elements for ZNF415 Gene

Transcription factor binding sites by QIAGEN in the ZNF415 gene promoter:

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF415 Gene

Start:
53,107,879 bp from pter
End:
53,133,077 bp from pter
Size:
25,199 bases
Orientation:
Minus strand

Genomic View for ZNF415 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF415 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF415 Gene

Proteins for ZNF415 Gene

  • Protein details for ZNF415 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q09FC8-ZN415_HUMAN
    Recommended name:
    Zinc finger protein 415
    Protein Accession:
    Q09FC8
    Secondary Accessions:
    • F5H287
    • Q09FC7
    • Q09FC9
    • Q09FD0
    • Q6NSZ2
    • Q6P3S0
    • Q9NUR2

    Protein attributes for ZNF415 Gene

    Size:
    603 amino acids
    Molecular mass:
    68798 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF415 Gene

neXtProt entry for ZNF415 Gene

Proteomics data for ZNF415 Gene at MOPED

Post-translational modifications for ZNF415 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF415 Gene

Domains for ZNF415 Gene

Gene Families for ZNF415 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF415 Gene

Suggested Antigen Peptide Sequences for ZNF415 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q09FC8

UniProtKB/Swiss-Prot:

ZN415_HUMAN :
  • Q09FC8
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF415: view

Function for ZNF415 Gene

Molecular function for ZNF415 Gene

UniProtKB/Swiss-Prot Function: Involved in transcriptional regulation. Transcriptional activity differed among the various isoforms. All isoforms except isoform 3 seem to suppresses the transcriptional activities of AP-1 and p53/TP53.

Gene Ontology (GO) - Molecular Function for ZNF415 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF415: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF415 Gene

Localization for ZNF415 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF415 Gene

Nucleus. Cytoplasm. Note=Isoforms 1, isoform 2, isoform 4 and isoform 5 showed both nuclear and cytoplasm localization. Isoform 3 localized only to nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF415 Gene COMPARTMENTS Subcellular localization image for ZNF415 gene
Compartment Confidence
nucleus 5
cytoskeleton 4
cytosol 3

Gene Ontology (GO) - Cellular Components for ZNF415 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005730 nucleolus IDA --
GO:0005737 cytoplasm IEA --
GO:0015630 microtubule cytoskeleton IDA --
genes like me logo Genes that share ontologies with ZNF415: view

Pathways for ZNF415 Gene

SuperPathways for ZNF415 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF415: view

Pathways by source for ZNF415 Gene

2 Reactome pathways for ZNF415 Gene

Gene Ontology (GO) - Biological Process for ZNF415 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF415: view

Transcripts for ZNF415 Gene

Unigene Clusters for ZNF415 Gene

Zinc finger protein 415:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF415

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF415
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF415 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c · 8d ^ 9a · 9b · 9c ^ 10a · 10b · 10c · 10d · 10e · 10f · 10g ·
SP1: - - - - - - - -
SP2: - - - - - - - - -
SP3: - - - -
SP4: - - - - - - - - - - - - -
SP5: - - - - - - -
SP6: - - - - - - - - - -
SP7: - - - - - - - - - - - - -
SP8: - - - - - -
SP9: - - - - - - - - - - - - - -
SP10: - - - - - - -
SP11: - - - - - - - - - - - - - - -
SP12: - - - - - - - - - - - - - -
SP13: - - - - - - -
SP14: - - - - - -
SP15: - - - - - - - - - - - - - -
SP16: - - - - - - - - - - - -
SP17: - - - - - - - - - - - -
SP18: - - - -
SP19: - - - - - - - - - - - - - - - -
SP20: - - - - - - - - - - - - - - -
SP21: - - - - - - - - - - - - - - - -
SP22: - - - -
SP23: - - - - - - - - - - - - - - - - -

ExUns: 10h · 10i · 10j · 10k · 10l · 10m · 10n
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:

Relevant External Links for ZNF415 Gene

GeneLoc Exon Structure for
ZNF415
ECgene alternative splicing isoforms for
ZNF415

Expression for ZNF415 Gene

mRNA expression in normal human tissues for ZNF415 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF415 Gene

SOURCE GeneReport for Unigene cluster for ZNF415 Gene Hs.147765

mRNA Expression by UniProt/SwissProt for ZNF415 Gene

Q09FC8-ZN415_HUMAN
Tissue specificity: Expressed in all tissues examined. Isoforms are differentially expressed. Isoform 3 and isoform 5 were highly expressed, isoform 4 moderately expressed, isoform 2 lower expression, the lowest expression level was seem with isoform 1.
genes like me logo Genes that share expressions with ZNF415: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ZNF415 Gene

Orthologs for ZNF415 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF415 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF415 35
  • 99.46 (n)
  • 99.1 (a)
ZNF415 36
  • 86 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 39 (a)
ManyToMany
LOC788599 35
  • 67.75 (n)
  • 53.93 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 52 (a)
ManyToMany
Species with no ortholog for ZNF415:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF415 Gene

ENSEMBL:
Gene Tree for ZNF415 (if available)
TreeFam:
Gene Tree for ZNF415 (if available)

Paralogs for ZNF415 Gene

Pseudogenes.org Pseudogenes for ZNF415 Gene

genes like me logo Genes that share paralogs with ZNF415: view

Variants for ZNF415 Gene

Sequence variations from dbSNP and Humsavar for ZNF415 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs3814 -- 53,107,934(+) TAACA(C/T)ATTTG utr-variant-3-prime, nc-transcript-variant
rs329738 -- 53,111,236(-) ggtac(C/T)ggctc intron-variant
rs329739 -- 53,111,180(-) tatgt(C/T)ttgtc intron-variant
rs1045764 -- 53,108,220(-) CTTAC(A/G)AGTAC utr-variant-3-prime, nc-transcript-variant
rs1054484 -- 53,109,736(-) GATGA(C/T)GAAAG synonymous-codon, reference, nc-transcript-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF415 Gene

Variant ID Type Subtype PubMed ID
esv2718787 CNV Deletion 23290073
dgv1116e1 CNV Complex 17122850
nsv428370 CNV Loss 18775914
nsv912342 CNV Gain 21882294
nsv912343 CNV Loss 21882294
dgv3991n71 CNV Gain+Loss 21882294
nsv435700 CNV Deletion 17901297
esv2488809 CNV Deletion 19546169
nsv527053 CNV Gain 19592680
nsv912345 CNV Loss 21882294
nsv470153 CNV Loss 18288195
dgv429n27 CNV Gain 19166990
esv2718810 CNV Deletion 23290073
esv8151 CNV Loss 19470904
nsv515862 CNV Gain+Loss 19592680
dgv3992n71 CNV Gain 21882294
nsv912349 CNV Gain 21882294
esv2228870 CNV Deletion 18987734
esv5924 CNV Loss 19470904
esv1316926 CNV Deletion 17803354
esv2718811 CNV Deletion 23290073
esv1006571 CNV Deletion 20482838
esv23288 CNV Gain 19812545
nsv912350 CNV Gain 21882294

Relevant External Links for ZNF415 Gene

HapMap Linkage Disequilibrium report
ZNF415

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF415 Gene

Disorders for ZNF415 Gene

Relevant External Links for ZNF415

Genetic Association Database (GAD)
ZNF415
genes like me logo Genes that share disorders with ZNF415: view

No data available for UniProtKB/Swiss-Prot for ZNF415 Gene

Publications for ZNF415 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4
  2. A novel human gene ZNF415 with five isoforms inhibits AP-1- and p53- mediated transcriptional activity. (PMID: 17055453) Cheng Y. … Liu M. (Biochem. Biophys. Res. Commun. 2006) 3 4
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for ZNF415 Gene

Sources for ZNF415 Gene

Back to Top

Content