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Aliases for ZNF414 Gene

Aliases for ZNF414 Gene

  • Zinc Finger Protein 414 2 3 5
  • ZFP414 3

External Ids for ZNF414 Gene

Previous GeneCards Identifiers for ZNF414 Gene

  • GC19M008483
  • GC19M008230
  • GC19M008575

Summaries for ZNF414 Gene

GeneCards Summary for ZNF414 Gene

ZNF414 (Zinc Finger Protein 414) is a Protein Coding gene.

UniProtKB/Swiss-Prot for ZNF414 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF414 Gene

Genomics for ZNF414 Gene

Regulatory Elements for ZNF414 Gene

Promoters for ZNF414 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF414 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF414 Gene

Chromosome:
19
Start:
8,509,678 bp from pter
End:
8,514,164 bp from pter
Size:
4,487 bases
Orientation:
Minus strand

Genomic View for ZNF414 Gene

Genes around ZNF414 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF414 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF414 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF414 Gene

Proteins for ZNF414 Gene

  • Protein details for ZNF414 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96IQ9-ZN414_HUMAN
    Recommended name:
    Zinc finger protein 414
    Protein Accession:
    Q96IQ9
    Secondary Accessions:
    • A8MY94

    Protein attributes for ZNF414 Gene

    Size:
    312 amino acids
    Molecular mass:
    32782 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF414 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF414 Gene

Proteomics data for ZNF414 Gene at MOPED

Post-translational modifications for ZNF414 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF414 Gene

Antibody Products

No data available for DME Specific Peptides for ZNF414 Gene

Domains & Families for ZNF414 Gene

Gene Families for ZNF414 Gene

Protein Domains for ZNF414 Gene

Suggested Antigen Peptide Sequences for ZNF414 Gene

Graphical View of Domain Structure for InterPro Entry

Q96IQ9

UniProtKB/Swiss-Prot:

ZN414_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 3 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 3 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF414: view

Function for ZNF414 Gene

Molecular function for ZNF414 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF414: view

Animal Model Products

CRISPR Products

miRNA for ZNF414 Gene

miRTarBase miRNAs that target ZNF414

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF414 Gene

Localization for ZNF414 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF414 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF414 Gene COMPARTMENTS Subcellular localization image for ZNF414 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF414 Gene

Pathways & Interactions for ZNF414 Gene

SuperPathways for ZNF414 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF414 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZNF414 Gene

Drugs & Compounds for ZNF414 Gene

No Compound Related Data Available

Transcripts for ZNF414 Gene

Unigene Clusters for ZNF414 Gene

Zinc finger protein 414:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF414 Gene

No ASD Table

Relevant External Links for ZNF414 Gene

GeneLoc Exon Structure for
ZNF414
ECgene alternative splicing isoforms for
ZNF414

Expression for ZNF414 Gene

mRNA expression in normal human tissues for ZNF414 Gene

Protein differential expression in normal tissues from HIPED for ZNF414 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (38.4) and Pancreatic juice (19.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF414 Gene



SOURCE GeneReport for Unigene cluster for ZNF414 Gene Hs.515114

genes like me logo Genes that share expression patterns with ZNF414: view

Protein tissue co-expression partners for ZNF414 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF414 Gene

Orthologs for ZNF414 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF414 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF414 36
  • 97 (a)
OneToOne
ZNF414 35
  • 99.35 (n)
  • 100 (a)
cow
(Bos Taurus)
Mammalia ZNF414 35
  • 87.4 (n)
  • 87.66 (a)
ZNF414 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF414 36
  • 67 (a)
OneToOne
ZNF414 35
  • 88.46 (n)
  • 89.32 (a)
mouse
(Mus musculus)
Mammalia Zfp414 35
  • 80 (n)
  • 81.02 (a)
Zfp414 16
Zfp414 36
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF414 36
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF414 36
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp414 35
  • 81.19 (n)
  • 82.09 (a)
chicken
(Gallus gallus)
Aves ZNF414 36
  • 34 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ZNF414 36
  • 31 (a)
OneToOne
Species with no ortholog for ZNF414:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF414 Gene

ENSEMBL:
Gene Tree for ZNF414 (if available)
TreeFam:
Gene Tree for ZNF414 (if available)

Paralogs for ZNF414 Gene

No data available for Paralogs for ZNF414 Gene

Variants for ZNF414 Gene

Sequence variations from dbSNP and Humsavar for ZNF414 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs8100431 - 8,513,151(+) CCTGC(C/T)GCATC reference, missense
rs1064010 - 8,513,116(-) GCCAG(C/T)CTGGC reference, missense
rs1064009 -- 8,513,234(-) GCCCC(C/T)TCCTC reference, synonymous-codon
rs2042300 -- 8,515,718(-) ACGAA(C/T)ACCTC upstream-variant-2KB
rs2042301 -- 8,515,494(-) cctgc(A/G)tgacc upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF414 Gene

Variant ID Type Subtype PubMed ID
nsv911004 CNV Loss 21882294
dgv3720n71 CNV Loss 21882294
dgv3721n71 CNV Loss 21882294
nsv458350 CNV Loss 19166990
dgv396n27 CNV Loss 19166990
dgv3722n71 CNV Loss 21882294
dgv3723n71 CNV Loss 21882294

Variation tolerance for ZNF414 Gene

Gene Damage Index Score: 10.24; 90.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF414 Gene

HapMap Linkage Disequilibrium report
ZNF414

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF414 Gene

Disorders for ZNF414 Gene

Relevant External Links for ZNF414

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF414

No disorders were found for ZNF414 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF414 Gene

Publications for ZNF414 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. (PMID: 21044950) Lee O.H. … Songyang Z. (Mol. Cell Proteomics 2011) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF414 Gene

Sources for ZNF414 Gene

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