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Aliases for ZNF414 Gene

Aliases for ZNF414 Gene

  • Zinc Finger Protein 414 2 3
  • ZFP414 3

External Ids for ZNF414 Gene

Previous GeneCards Identifiers for ZNF414 Gene

  • GC19M008483
  • GC19M008230
  • GC19M008575

Summaries for ZNF414 Gene

GeneCards Summary for ZNF414 Gene

ZNF414 (Zinc Finger Protein 414) is a Protein Coding gene.

UniProtKB/Swiss-Prot for ZNF414 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF414 Gene

Genomics for ZNF414 Gene

Regulatory Elements for ZNF414 Gene

Genomic Location for ZNF414 Gene

8,509,678 bp from pter
8,514,164 bp from pter
4,487 bases
Minus strand

Genomic View for ZNF414 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF414 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF414 Gene

Proteins for ZNF414 Gene

  • Protein details for ZNF414 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 414
    Protein Accession:
    Secondary Accessions:
    • A8MY94

    Protein attributes for ZNF414 Gene

    312 amino acids
    Molecular mass:
    32782 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF414 Gene


neXtProt entry for ZNF414 Gene

Proteomics data for ZNF414 Gene at MOPED

Post-translational modifications for ZNF414 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF414 Gene

No data available for DME Specific Peptides for ZNF414 Gene

Domains for ZNF414 Gene

Gene Families for ZNF414 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF414 Gene


Suggested Antigen Peptide Sequences for ZNF414 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q96IQ9
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 3 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF414: view

Function for ZNF414 Gene

Molecular function for ZNF414 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF414 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF414: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF414 Gene

Localization for ZNF414 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF414 Gene

Subcellular locations from

Jensen Localization Image for ZNF414 Gene COMPARTMENTS Subcellular localization image for ZNF414 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF414 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF414: view

Pathways for ZNF414 Gene

SuperPathways for ZNF414 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF414 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF414: view

No data available for Pathways by source for ZNF414 Gene

Transcripts for ZNF414 Gene

Unigene Clusters for ZNF414 Gene

Zinc finger protein 414:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF414 Gene

No ASD Table

Relevant External Links for ZNF414 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF414 Gene

mRNA expression in normal human tissues for ZNF414 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF414 Gene

SOURCE GeneReport for Unigene cluster for ZNF414 Gene Hs.515114

genes like me logo Genes that share expressions with ZNF414: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF414 Gene

Orthologs for ZNF414 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF414 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF414 35
  • 99.35 (n)
  • 100 (a)
ZNF414 36
  • 97 (a)
(Bos Taurus)
Mammalia ZNF414 35
  • 87.4 (n)
  • 87.66 (a)
ZNF414 36
  • 89 (a)
(Canis familiaris)
Mammalia ZNF414 35
  • 88.46 (n)
  • 89.32 (a)
ZNF414 36
  • 67 (a)
(Mus musculus)
Mammalia Zfp414 35
  • 80 (n)
  • 81.02 (a)
Zfp414 16
Zfp414 36
  • 79 (a)
(Monodelphis domestica)
Mammalia ZNF414 36
  • 60 (a)
(Ornithorhynchus anatinus)
Mammalia ZNF414 36
  • 55 (a)
(Rattus norvegicus)
Mammalia Zfp414 35
  • 81.19 (n)
  • 82.09 (a)
(Gallus gallus)
Aves ZNF414 36
  • 34 (a)
(Danio rerio)
Actinopterygii ZNF414 36
  • 31 (a)
Species with no ortholog for ZNF414:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF414 Gene

Gene Tree for ZNF414 (if available)
Gene Tree for ZNF414 (if available)

Paralogs for ZNF414 Gene

No data available for Paralogs for ZNF414 Gene

Variants for ZNF414 Gene

Sequence variations from dbSNP and Humsavar for ZNF414 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs7175 -- 8,511,786(-) CTGCC(A/C/G/T)TTCCC synonymous-codon, reference
rs1064009 -- 8,513,234(-) GCCCC(C/T)TCCTC synonymous-codon, reference
rs1064010 - 8,513,116(-) GCCAG(C/T)CTGGC reference, missense
rs1133594 -- 8,511,008(-) CCGAG(C/T)CGCAT reference, synonymous-codon, intron-variant
rs1141019 -- 8,513,315(-) ATCCC(A/C/G)GACAT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for ZNF414 Gene

Variant ID Type Subtype PubMed ID
nsv911004 CNV Loss 21882294
dgv3720n71 CNV Loss 21882294
dgv3721n71 CNV Loss 21882294
nsv458350 CNV Loss 19166990
dgv396n27 CNV Loss 19166990
dgv3722n71 CNV Loss 21882294
dgv3723n71 CNV Loss 21882294

Relevant External Links for ZNF414 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF414 Gene

Disorders for ZNF414 Gene

No disorders were found for ZNF414 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF414 Gene

Publications for ZNF414 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. (PMID: 21044950) Lee O.H. … Songyang Z. (Mol. Cell Proteomics 2011) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for ZNF414 Gene

Sources for ZNF414 Gene

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