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Aliases for ZNF407 Gene

Aliases for ZNF407 Gene

  • Zinc Finger Protein 407 2 3
  • KIAA1703 4

External Ids for ZNF407 Gene

Previous GeneCards Identifiers for ZNF407 Gene

  • GC18P072345
  • GC18P072108
  • GC18P070472
  • GC18P070474
  • GC18P069029

Summaries for ZNF407 Gene

Entrez Gene Summary for ZNF407 Gene

  • This gene encodes a zinc finger protein whose exact function is not known. It may be involved in transcriptional regulation. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

GeneCards Summary for ZNF407 Gene

ZNF407 (Zinc Finger Protein 407) is a Protein Coding gene. Diseases associated with ZNF407 include non-syndromic intellectual disability and syndromic intellectual disability. An important paralog of this gene is REST.

UniProtKB/Swiss-Prot for ZNF407 Gene

  • May be involved in transcriptional regulation

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF407 Gene

Genomics for ZNF407 Gene

Regulatory Elements for ZNF407 Gene

Genomic Location for ZNF407 Gene

74,597,870 bp from pter
75,065,673 bp from pter
467,804 bases
Plus strand

Genomic View for ZNF407 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF407 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF407 Gene

Proteins for ZNF407 Gene

  • Protein details for ZNF407 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 407
    Protein Accession:
    Secondary Accessions:
    • B5MD54
    • Q96MY0
    • Q9H8A1
    • Q9NXD4
    • Q9NXD7

    Protein attributes for ZNF407 Gene

    2248 amino acids
    Molecular mass:
    247367 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA91077.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA91080.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF407 Gene


neXtProt entry for ZNF407 Gene

Proteomics data for ZNF407 Gene at MOPED

Post-translational modifications for ZNF407 Gene

  • Ubiquitination at Lys1364
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF407 Gene

Antibody Products

No data available for DME Specific Peptides for ZNF407 Gene

Domains for ZNF407 Gene

Gene Families for ZNF407 Gene

Protein Domains for ZNF407 Gene

Suggested Antigen Peptide Sequences for ZNF407 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 22 C2H2-type zinc fingers.
  • Contains 22 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF407: view

Function for ZNF407 Gene

Molecular function for ZNF407 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF407 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding --
genes like me logo Genes that share ontologies with ZNF407: view

Phenotypes for ZNF407 Gene

GenomeRNAi human phenotypes for ZNF407:
genes like me logo Genes that share phenotypes with ZNF407: view

Animal Model Products

CRISPR Products

miRNA for ZNF407 Gene

miRTarBase miRNAs that target ZNF407

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF407 Gene

Localization for ZNF407 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF407 Gene

Subcellular locations from

Jensen Localization Image for ZNF407 Gene COMPARTMENTS Subcellular localization image for ZNF407 gene
Compartment Confidence
nucleus 3
cytosol 1

Gene Ontology (GO) - Cellular Components for ZNF407 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF407: view

Pathways for ZNF407 Gene

SuperPathways for ZNF407 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF407 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF407: view

No data available for Pathways by source for ZNF407 Gene

Transcripts for ZNF407 Gene

Unigene Clusters for ZNF407 Gene

Zinc finger protein 407:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF407 Gene

No ASD Table

Relevant External Links for ZNF407 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF407 Gene

mRNA expression in normal human tissues for ZNF407 Gene

Protein differential expression in normal tissues for ZNF407 Gene

This gene is overexpressed in Fetal heart (39.5), Heart (14.4), and Skin (7.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF407 Gene

SOURCE GeneReport for Unigene cluster for ZNF407 Gene Hs.536490

genes like me logo Genes that share expressions with ZNF407: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for ZNF407 Gene

Orthologs for ZNF407 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF407 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF407 35
  • 76.98 (n)
  • 74.52 (a)
ZNF407 36
  • 74 (a)
(Canis familiaris)
Mammalia ZNF407 35
  • 81.5 (n)
  • 78.17 (a)
ZNF407 36
  • 77 (a)
(Mus musculus)
Mammalia Zfp407 35
  • 79.23 (n)
  • 75.76 (a)
Zfp407 16
Zfp407 36
  • 75 (a)
(Pan troglodytes)
Mammalia ZNF407 35
  • 99.21 (n)
  • 98.9 (a)
ZNF407 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Zfp407 35
  • 78.83 (n)
  • 75.66 (a)
(Monodelphis domestica)
Mammalia ZNF407 36
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia ZNF407 36
  • 53 (a)
(Gallus gallus)
Aves ZNF407 35
  • 64.52 (n)
  • 59.81 (a)
ZNF407 36
  • 56 (a)
(Anolis carolinensis)
Reptilia ZNF407 36
  • 46 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia znf407 35
  • 63.5 (n)
  • 61.5 (a)
(Danio rerio)
Actinopterygii LOC101884678 35
  • 62.99 (n)
  • 62.47 (a)
ZNF407 36
  • 67 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG31612 36
  • 10 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 19 (a)
Species with no ortholog for ZNF407:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF407 Gene

Gene Tree for ZNF407 (if available)
Gene Tree for ZNF407 (if available)

Paralogs for ZNF407 Gene

Paralogs for ZNF407 Gene

genes like me logo Genes that share paralogs with ZNF407: view

Variants for ZNF407 Gene

Sequence variations from dbSNP and Humsavar for ZNF407 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs471183 -- 74,691,897(-) aggct(C/G)gtcta intron-variant
rs471821 -- 74,674,531(-) CTATG(C/G)TGTCA intron-variant
rs473008 -- 74,664,684(-) GGAGG(A/G)GCAGC intron-variant
rs473638 -- 74,646,598(-) GAATA(C/T)ACAAA intron-variant
rs474081 -- 74,736,605(+) TTAAC(A/G)TATAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF407 Gene

Variant ID Type Subtype PubMed ID
nsv909919 CNV Gain 21882294
nsv909921 CNV Gain 21882294
nsv2357 CNV Insertion 18451855
nsv2358 CNV Insertion 18451855
esv2717349 CNV Deletion 23290073
esv2673740 CNV Deletion 23128226
esv2034794 CNV Deletion 18987734
esv2665165 CNV Deletion 23128226
esv2717350 CNV Deletion 23290073
esv999235 CNV Deletion 20482838
esv1570874 CNV Deletion 17803354
nsv523996 CNV Gain 19592680
esv2657517 CNV Deletion 23128226
esv2717352 CNV Deletion 23290073
nsv516801 CNV Loss 19592680
esv2675767 CNV Deletion 23128226
nsv2359 CNV Loss 18451855
esv2521516 CNV Deletion 19546169
esv2717353 CNV Deletion 23290073
esv2612943 CNV Deletion 19546169
esv2561068 CNV Deletion 19546169
nsv518563 CNV Gain 19592680
esv2717354 CNV Deletion 23290073
esv2053114 CNV Deletion 18987734
esv4223 CNV Deletion 18987735
esv2717355 CNV Deletion 23290073
nsv2360 CNV Loss 18451855

Relevant External Links for ZNF407 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF407 Gene

Disorders for ZNF407 Gene

Relevant External Links for ZNF407

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with ZNF407: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ZNF407 Gene

Publications for ZNF407 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11214970) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping. (PMID: 19690890) McDonough C.W. … Bowden D.W. (Hum. Genet. 2009) 3 48
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  5. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48

Products for ZNF407 Gene

Sources for ZNF407 Gene

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