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Aliases for ZNF394 Gene

Aliases for ZNF394 Gene

  • Zinc Finger Protein 394 2 3
  • Zinc Finger Protein With KRAB And SCAN Domains 14 3 4
  • ZKSCAN14 3 4
  • Zinc Finger Protein 99 3
  • ZSCAN46 3

External Ids for ZNF394 Gene

Previous GeneCards Identifiers for ZNF394 Gene

  • GC00U991239
  • GC07M098702
  • GC07M098735
  • GC07M098928
  • GC07M099088
  • GC07M093727

Summaries for ZNF394 Gene

GeneCards Summary for ZNF394 Gene

ZNF394 (Zinc Finger Protein 394) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF396.

UniProtKB/Swiss-Prot for ZNF394 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF394 Gene

Genomics for ZNF394 Gene

Regulatory Elements for ZNF394 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF394 Gene

Start:
99,486,519 bp from pter
End:
99,500,324 bp from pter
Size:
13,806 bases
Orientation:
Minus strand

Genomic View for ZNF394 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF394 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF394 Gene

Proteins for ZNF394 Gene

  • Protein details for ZNF394 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q53GI3-ZN394_HUMAN
    Recommended name:
    Zinc finger protein 394
    Protein Accession:
    Q53GI3
    Secondary Accessions:
    • A4D281
    • Q05DA6
    • Q6P5X9
    • Q8TB27
    • Q9HA37
    • Q9UD51

    Protein attributes for ZNF394 Gene

    Size:
    561 amino acids
    Molecular mass:
    64256 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF394 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF394 Gene

Proteomics data for ZNF394 Gene at MOPED

Post-translational modifications for ZNF394 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF394 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ZNF394 Gene

Domains for ZNF394 Gene

Gene Families for ZNF394 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF394 Gene

Graphical View of Domain Structure for InterPro Entry

Q53GI3

UniProtKB/Swiss-Prot:

ZN394_HUMAN :
  • Q53GI3
Domain:
  • Contains 1 KRAB domain.
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 7 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF394: view

Function for ZNF394 Gene

Molecular function for ZNF394 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF394 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF394: view

Phenotypes for ZNF394 Gene

MGI mutant phenotypes for ZNF394:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with ZNF394: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF394

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF394 Gene

Localization for ZNF394 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF394 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF394 Gene COMPARTMENTS Subcellular localization image for ZNF394 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF394 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with ZNF394: view

Pathways for ZNF394 Gene

SuperPathways for ZNF394 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF394: view

Pathways by source for ZNF394 Gene

2 Reactome pathways for ZNF394 Gene

Gene Ontology (GO) - Biological Process for ZNF394 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF394: view

Transcripts for ZNF394 Gene

Unigene Clusters for ZNF394 Gene

Zinc finger protein 394:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF394

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF394 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b
SP1: -
SP2: - -
SP3:

Relevant External Links for ZNF394 Gene

GeneLoc Exon Structure for
ZNF394
ECgene alternative splicing isoforms for
ZNF394

Expression for ZNF394 Gene

mRNA expression in normal human tissues for ZNF394 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZNF394 Gene

This gene is overexpressed in Whole Blood (6.3).

Protein differential expression in normal tissues for ZNF394 Gene

This gene is overexpressed in Breast (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF394 Gene

SOURCE GeneReport for Unigene cluster for ZNF394 Gene Hs.386324

genes like me logo Genes that share expressions with ZNF394: view

Expression partners for ZNF394 Gene

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for ZNF394 Gene

Orthologs for ZNF394 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF394 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF394 35
  • 75.8 (n)
  • 66.6 (a)
ZNF394 36
  • 56 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF394 35
  • 78.16 (n)
  • 70.5 (a)
ZNF394 36
  • 62 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zkscan14 35
  • 74.25 (n)
  • 66.67 (a)
Zkscan14 16
Zkscan14 36
  • 66 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF394 35
  • 99.52 (n)
  • 98.57 (a)
ZNF394 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp394 35
  • 74.65 (n)
  • 66.99 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 33 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 36 (a)
ManyToMany
chicken
(Gallus gallus)
Aves ZFP92 36
  • 39 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 26 (a)
ManyToMany
Species with no ortholog for ZNF394:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF394 Gene

ENSEMBL:
Gene Tree for ZNF394 (if available)
TreeFam:
Gene Tree for ZNF394 (if available)

Paralogs for ZNF394 Gene

Selected SIMAP similar genes for ZNF394 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF394: view

Variants for ZNF394 Gene

Sequence variations from dbSNP and Humsavar for ZNF394 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs3735454 - 99,494,241(-) GGTGA(C/T)GTGGC reference, missense, intron-variant
rs7809322 -- 99,492,051(+) ctggg(C/T)gacag intron-variant
rs10215301 -- 99,488,700(+) caagg(C/G)gggtg intron-variant
rs10216265 -- 99,488,928(+) tccat(C/T)tcaaa intron-variant
rs10233903 -- 99,492,190(+) AAATA(A/G)AGTGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF394 Gene

Variant ID Type Subtype PubMed ID
nsv831069 CNV Loss 17160897

Relevant External Links for ZNF394 Gene

HapMap Linkage Disequilibrium report
ZNF394

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF394 Gene

Disorders for ZNF394 Gene

No disorders were found for ZNF394 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZNF394 Gene

Publications for ZNF394 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Inhibition of transcriptional activities of AP-1 and c-Jun by a new zinc finger protein ZNF394. (PMID: 15249231) Huang C. … Wu X. (Biochem. Biophys. Res. Commun. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for ZNF394 Gene

Sources for ZNF394 Gene

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