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Aliases for ZNF391 Gene

Aliases for ZNF391 Gene

  • Zinc Finger Protein 391 2 3 5
  • DJ153G14.3 3

External Ids for ZNF391 Gene

Previous GeneCards Identifiers for ZNF391 Gene

  • GC00U914161
  • GC06U900622
  • GC06P027477
  • GC06P027166

Summaries for ZNF391 Gene

GeneCards Summary for ZNF391 Gene

ZNF391 (Zinc Finger Protein 391) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF501.

UniProtKB/Swiss-Prot for ZNF391 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF391 Gene

Genomics for ZNF391 Gene

Regulatory Elements for ZNF391 Gene

Enhancers for ZNF391 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF391 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF391 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF391 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF391 Gene

27,374,615 bp from pter
27,403,908 bp from pter
29,294 bases
Plus strand

Genomic View for ZNF391 Gene

Genes around ZNF391 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF391 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF391 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF391 Gene

Proteins for ZNF391 Gene

  • Protein details for ZNF391 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 391
    Protein Accession:
    Secondary Accessions:
    • B4DH77

    Protein attributes for ZNF391 Gene

    358 amino acids
    Molecular mass:
    40659 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAB51755.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF391 Gene

Proteomics data for ZNF391 Gene at MOPED

Post-translational modifications for ZNF391 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF391 Gene

Antibody Products

No data available for DME Specific Peptides for ZNF391 Gene

Domains & Families for ZNF391 Gene

Gene Families for ZNF391 Gene

Protein Domains for ZNF391 Gene

Suggested Antigen Peptide Sequences for ZNF391 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF391: view

Function for ZNF391 Gene

Molecular function for ZNF391 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF391 Gene

GenomeRNAi human phenotypes for ZNF391:
genes like me logo Genes that share phenotypes with ZNF391: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF391 Gene

Localization for ZNF391 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF391 Gene

Subcellular locations from

Jensen Localization Image for ZNF391 Gene COMPARTMENTS Subcellular localization image for ZNF391 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF391 Gene

Pathways & Interactions for ZNF391 Gene

SuperPathways for ZNF391 Gene

No Data Available

Interacting Proteins for ZNF391 Gene

Gene Ontology (GO) - Biological Process for ZNF391 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZNF391 Gene

Drugs & Compounds for ZNF391 Gene

No Compound Related Data Available

Transcripts for ZNF391 Gene

mRNA/cDNA for ZNF391 Gene

(9) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF391 Gene

Zinc finger protein 391:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF391 Gene

No ASD Table

Relevant External Links for ZNF391 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF391 Gene

mRNA expression in normal human tissues for ZNF391 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF391 Gene

SOURCE GeneReport for Unigene cluster for ZNF391 Gene Hs.651176

genes like me logo Genes that share expression patterns with ZNF391: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF391 Gene

Orthologs for ZNF391 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF391 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF391 35
  • 88.64 (n)
  • 84.92 (a)
ZNF391 36
  • 85 (a)
(Canis familiaris)
Mammalia ZNF391 35
  • 85.64 (n)
  • 86.77 (a)
ZNF391 36
  • 88 (a)
(Pan troglodytes)
Mammalia ZNF391 35
  • 99.26 (n)
  • 98.6 (a)
ZNF391 36
  • 99 (a)
(Monodelphis domestica)
Mammalia ZNF391 36
  • 32 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100491165 35
  • 62.23 (n)
  • 58.87 (a)
Species with no ortholog for ZNF391:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF391 Gene

Gene Tree for ZNF391 (if available)
Gene Tree for ZNF391 (if available)

Paralogs for ZNF391 Gene

(517) SIMAP similar genes for ZNF391 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF391: view

Variants for ZNF391 Gene

Sequence variations from dbSNP and Humsavar for ZNF391 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs10807020 - 27,389,123(+) TTCGA(A/G)GGAAA intron-variant
rs10807021 - 27,389,146(+) TCGCG(G/T)GTGGT intron-variant
rs1022515 -- 27,398,028(-) ACATG(C/G)CTTTC intron-variant
rs1022517 -- 27,397,230(-) gctcc(C/G)ccttt intron-variant, upstream-variant-2KB
rs1022518 -- 27,397,107(-) ttacc(C/T)agtct intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF391 Gene

Variant ID Type Subtype PubMed ID
nsv5234 CNV Insertion 18451855
nsv517557 CNV Loss 19592680
nsv5235 CNV Loss 18451855

Variation tolerance for ZNF391 Gene

Residual Variation Intolerance Score: 72.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.93; 35.93% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF391 Gene

Disorders for ZNF391 Gene

Relevant External Links for ZNF391

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF391 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF391 Gene

Publications for ZNF391 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Keep your fingers off my DNA: protein-protein interactions mediated by C2H2 zinc finger domains. (PMID: 18253864) Brayer K.J. … Segal D.J. (Cell Biochem. Biophys. 2008) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3

Products for ZNF391 Gene

Sources for ZNF391 Gene