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Aliases for ZNF385D Gene

Aliases for ZNF385D Gene

  • Zinc Finger Protein 385D 2 3
  • Zinc Finger Protein 659 2 3 4
  • ZNF659 3 4

External Ids for ZNF385D Gene

Previous HGNC Symbols for ZNF385D Gene

  • ZNF659

Previous GeneCards Identifiers for ZNF385D Gene

  • GC03M021439
  • GC03M021412

Summaries for ZNF385D Gene

GeneCards Summary for ZNF385D Gene

ZNF385D (Zinc Finger Protein 385D) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF385B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF385D Gene

Genomics for ZNF385D Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF385D Gene

Start:
21,418,419 bp from pter
End:
22,373,321 bp from pter
Size:
954,903 bases
Orientation:
Minus strand

Genomic View for ZNF385D Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF385D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF385D Gene

No data available for Regulatory Elements for ZNF385D Gene

Proteins for ZNF385D Gene

  • Protein details for ZNF385D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H6B1-Z385D_HUMAN
    Recommended name:
    Zinc finger protein 385D
    Protein Accession:
    Q9H6B1
    Secondary Accessions:

    Protein attributes for ZNF385D Gene

    Size:
    395 amino acids
    Molecular mass:
    42296 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF385D Gene

Proteomics data for ZNF385D Gene at MOPED

Post-translational modifications for ZNF385D Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF385D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF385D Gene

Domains for ZNF385D Gene

Protein Domains for ZNF385D Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF385D Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H6B1

UniProtKB/Swiss-Prot:

Z385D_HUMAN :
  • Q9H6B1
Similarity:
  • Contains 3 matrin-type zinc fingers.
genes like me logo Genes that share domains with ZNF385D: view

No data available for Gene Families for ZNF385D Gene

Function for ZNF385D Gene

Gene Ontology (GO) - Molecular Function for ZNF385D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZNF385D: view

Phenotypes for ZNF385D Gene

GenomeRNAi human phenotypes for ZNF385D:
genes like me logo Genes that share phenotypes with ZNF385D: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF385D Gene

Localization for ZNF385D Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF385D Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF385D Gene COMPARTMENTS Subcellular localization image for ZNF385D gene
Compartment Confidence
nucleus 3
cytosol 1
golgi apparatus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ZNF385D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF385D: view

Pathways for ZNF385D Gene

SuperPathways for ZNF385D Gene

No Data Available

Interacting Proteins for ZNF385D Gene

Selected Interacting proteins: Q9H6B1-Z385D_HUMAN for ZNF385D Gene via I2D

Symbol External ID(s) Details
MAP2K2

Gene Ontology (GO) - Biological Process for ZNF385D Gene

None

No data available for Pathways by source for ZNF385D Gene

Transcripts for ZNF385D Gene

Unigene Clusters for ZNF385D Gene

Zinc finger protein 385D:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF385D

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF385D Gene

No ASD Table

Relevant External Links for ZNF385D Gene

GeneLoc Exon Structure for
ZNF385D
ECgene alternative splicing isoforms for
ZNF385D

Expression for ZNF385D Gene

mRNA expression in normal human tissues for ZNF385D Gene

mRNA differential expression in normal tissues according to GTEx for ZNF385D Gene

This gene is overexpressed in Artery - Aorta (6.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ZNF385D Gene

SOURCE GeneReport for Unigene cluster for ZNF385D Gene Hs.21026

genes like me logo Genes that share expressions with ZNF385D: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for ZNF385D Gene

Orthologs for ZNF385D Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF385D Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF385D 35
  • 95.58 (n)
  • 95.41 (a)
ZNF385D 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF385D 35
  • 84.99 (n)
  • 92.41 (a)
dog
(Canis familiaris)
Mammalia ZNF385D 35
  • 94.49 (n)
  • 98.97 (a)
ZNF385D 36
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF385D 36
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 85 (a)
OneToMany
-- 36
  • 99 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zfp385d 35
  • 87.79 (n)
  • 90.59 (a)
chicken
(Gallus gallus)
Aves ZNF385D 35
  • 88.86 (n)
  • 95.15 (a)
ZNF385D 36
  • 96 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF385D 36
  • 84 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf385d 35
  • 76.36 (n)
  • 78.83 (a)
zebrafish
(Danio rerio)
Actinopterygii ZNF385D 36
  • 51 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 17 (a)
OneToMany
Species with no ortholog for ZNF385D:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF385D Gene

ENSEMBL:
Gene Tree for ZNF385D (if available)
TreeFam:
Gene Tree for ZNF385D (if available)

Paralogs for ZNF385D Gene

Paralogs for ZNF385D Gene

Selected SIMAP similar genes for ZNF385D Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF385D: view

Variants for ZNF385D Gene

Sequence variations from dbSNP and Humsavar for ZNF385D Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1117 -- 22,044,317(+) AAAAC(G/T)ATTTC intron-variant
rs9700 -- 21,418,709(-) TTCTT(C/T)CCCAT utr-variant-3-prime
rs16768 -- 22,302,773(+) TAATG(G/T)TACTT intron-variant
rs149267 -- 21,539,499(+) CATGA(C/T)TTCTA intron-variant
rs151276 -- 21,536,305(-) TAATA(C/T)TTTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF385D Gene

Variant ID Type Subtype PubMed ID
nsv834630 CNV Loss 17160897
nsv238000 CNV Loss 16902084
nsv822029 CNV Gain 20364138
nsv522577 CNV Loss 19592680
esv2725024 CNV Deletion 23290073
esv271111 CNV Insertion 20981092
nsv834631 CNV Gain 17160897
nsv876612 CNV Gain 21882294
esv21508 CNV Gain 19812545
nsv527771 CNV Loss 19592680
esv2725025 CNV Deletion 23290073
esv2657428 CNV Deletion 23128226
esv5738 CNV Loss 19470904
esv28084 CNV Loss 19812545
dgv799n67 CNV Loss 20364138
nsv514140 CNV Loss 21397061
esv2725026 CNV Deletion 23290073
esv2665339 CNV Deletion 23128226
esv2668952 CNV Deletion 23128226
esv2751992 CNV Gain 17911159

Relevant External Links for ZNF385D Gene

HapMap Linkage Disequilibrium report
ZNF385D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF385D Gene

Disorders for ZNF385D Gene

Relevant External Links for ZNF385D

Genetic Association Database (GAD)
ZNF385D
Human Genome Epidemiology (HuGE) Navigator
ZNF385D
genes like me logo Genes that share disorders with ZNF385D: view

No data available for UniProtKB/Swiss-Prot for ZNF385D Gene

Publications for ZNF385D Gene

  1. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. (PMID: 18711365) Ferreira M.A. … Craddock N. (Nat. Genet. 2008) 3 48
  2. Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. (PMID: 18821565) Lasky-Su J. … Faraone S.V. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008) 3 48
  3. Host determinants of HIV-1 control in African Americans. (PMID: 20205591) Pelak K. … . (J. Infect. Dis. 2010) 3 48
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  5. Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study. (PMID: 20522523) KasperaviciAte D. … Sisodiya S.M. (Brain 2010) 3 48

Products for ZNF385D Gene

Sources for ZNF385D Gene

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