ZNF385C Gene
protein-coding GIFtS: 38
GCID: GC17M040177
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zinc finger protein 385C
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Aliases
for ZNF385C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 385C1 2 |
Export aliases for ZNF385C gene to outside databasesPrevious GC identifers: GC17M037432 GC17M035942 |
Summaries
for ZNF385C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ZNF385C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF385C gene promoter:
SRF Spz1 AML1a SRF (504 AA) Pax-2 Pax-2a Nkx2-5 Roaz AREB6 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF385C
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF385C |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q21.2 Ensembl cytogenetic band: 17q21.2 HGNC cytogenetic band: 17q21.2ZNF385C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M040177: view genomic region
(about GC identifiers)
Start:
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40,177,055 bp from pter |
End:
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40,250,485 bp from pter |
Size:
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73,431 bases |
Orientation:
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minus strand |
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Proteins
for ZNF385C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: Z385C_HUMAN, Q66K41 (See
protein sequence)Recommended Name: Zinc finger protein 385C Size: 422 amino acids; 44107 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q4G0J1Alternative splicing: 2 isoforms: Q66K41-1 Q66K41-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF385C: NX_Q66K41
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q66K41
ZNF385C Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001229633.1
ENSEMBL proteins: ENSP00000411514
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF385C for ontologies About GeneDecksing
ZNF385C Antibody Products:
Assay Products for ZNF385C: |
Protein
Domains /
Families
for ZNF385C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF385C for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q66K41ProtoNet protein and cluster: Q66K41 1 Blocks protein family: IPB003604 Zn-finger
UniProtKB/Swiss-Prot: Z385C_HUMAN, Q66K41Similarity: Contains 3 matrin-type zinc fingers |
Function
for ZNF385C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF385C |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003676 | nucleic acid binding |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
ZNF385C for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF385C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF385C
|
Drugs & Compounds
for ZNF385C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF385C
Search CenterWatch for drugs/clinical trials and news about ZNF385C / Z385C 
|
Transcripts
for ZNF385C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF385C gene (2 alternative transcripts): NM_001013624.2 NM_001242704.1 Unigene Cluster for ZNF385C: Zinc finger protein 385C Hs.443140 [show with all ESTs]Unigene Representative Sequence: NM_0012427044 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000436535 ENST00000496039 ENST00000461831(uc021txr.1) ENST00000453355
Additional cDNA sequence: BC080613.1 8 DOTS entries: DT.101961705 DT.100705586 DT.120967505 DT.95143111 DT.120967366 DT.120967439 DT.120967445 DT.95143112 24/31 AceView cDNA sequences (see all 31): BF511938 BC067901 AA327956 AI073431 CN478554 AI087932 BX373464 AA578415 BQ070064 BF433600 BC080613 BM719355 BX411821 AA558665 BQ185803 BF513664 BE843041 AW243839 BE245251 H06009 BI562725 H05959 BE075759 BM994903
GeneLoc Exon Structure
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Expression
for ZNF385C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF385C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGTCAATGT
About this image
See ZNF385C Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF385C
SOURCE GeneReport for Unigene cluster: Hs.443140
SABiosciences Custom PCR Arrays for ZNF385C
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF385C
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF385C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF385C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF385C | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF385C |
Orthologs
for ZNF385C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF385C gene from 3/8 species (see all 8) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ZNF385C6 |
Uncharacterized protein |
63(a) |
1 ↔ 1 |
27(4411575-4412923) |
lizard
(Anolis carolinensis) |
Reptilia |
ZNF385C6 |
-- |
57(a) |
1 ↔ 1 |
6(66314864-66337723) |
zebrafish
(Danio rerio) |
Actinopterygii |
si:dkey-26l17.16 |
si:dkey-26l17.1 |
43(a) |
1 ↔ 1 |
3(17457817-17576771) |
ENSEMBL Gene Tree for ZNF385C (if available)
TreeFam Gene Tree for ZNF385C (if available) |
Paralogs
for ZNF385C gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF385C gene
- ZNF385A2 ZNF385D2 ZNF385B2
4 SIMAP similar genes for ZNF385C using alignment to 2 protein entries: Z385C_HUMAN (see all proteins):ZNF385D ZNF385B FLJ25270 ZNF385A
ZNF385C for paralogs About GeneDecksing
|
Genomic Variants
for ZNF385C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF385C (40177055 - 40250485 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF385C: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF385C |
|
Disorders
/ Diseases
for ZNF385C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF385C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF385C gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF385C) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF385C gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ZNF385C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF385C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF385C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF385C | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF385C gene:
Search GeneIP for patents involving ZNF385C
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF385C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF385C | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF385C | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF385C | | | OriGene Protein Over-expression Lysate for ZNF385C | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF385C | | Browse 3'-UTR reporter clones for miRNA target validation | | | Browse OriGene untagged cDNA clones in CMV expression vector | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF385C | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ZNF385C | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF385C | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF385C | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF385C | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF385C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF385C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF385C |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF385C |
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