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Aliases for ZNF385C Gene

Aliases for ZNF385C Gene

  • Zinc Finger Protein 385C 2 3
  • CTD-2132N18.2 3
  • CTD-2132N18.4 3

External Ids for ZNF385C Gene

Previous GeneCards Identifiers for ZNF385C Gene

  • GC17M037432
  • GC17M040177
  • GC17M035942

Summaries for ZNF385C Gene

GeneCards Summary for ZNF385C Gene

ZNF385C (Zinc Finger Protein 385C) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF385B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF385C Gene

Genomics for ZNF385C Gene

Regulatory Elements for ZNF385C Gene

Genomic Location for ZNF385C Gene

Start:
42,025,576 bp from pter
End:
42,065,365 bp from pter
Size:
39,790 bases
Orientation:
Minus strand

Genomic View for ZNF385C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF385C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF385C Gene

Proteins for ZNF385C Gene

  • Protein details for ZNF385C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q66K41-Z385C_HUMAN
    Recommended name:
    Zinc finger protein 385C
    Protein Accession:
    Q66K41
    Secondary Accessions:
    • Q4G0J1

    Protein attributes for ZNF385C Gene

    Size:
    422 amino acids
    Molecular mass:
    44107 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF385C Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF385C Gene

Proteomics data for ZNF385C Gene at MOPED

Post-translational modifications for ZNF385C Gene

  • Ubiquitination at Lys346
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF385C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF385C Gene

Domains for ZNF385C Gene

Protein Domains for ZNF385C Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF385C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q66K41

UniProtKB/Swiss-Prot:

Z385C_HUMAN :
  • Q66K41
Similarity:
  • Contains 3 matrin-type zinc fingers.
genes like me logo Genes that share domains with ZNF385C: view

No data available for Gene Families for ZNF385C Gene

Function for ZNF385C Gene

Gene Ontology (GO) - Molecular Function for ZNF385C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZNF385C: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF385C Gene

Localization for ZNF385C Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF385C Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF385C Gene COMPARTMENTS Subcellular localization image for ZNF385C gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF385C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF385C: view

Pathways for ZNF385C Gene

SuperPathways for ZNF385C Gene

No Data Available

Interacting Proteins for ZNF385C Gene

Gene Ontology (GO) - Biological Process for ZNF385C Gene

None

No data available for Pathways by source for ZNF385C Gene

Transcripts for ZNF385C Gene

Unigene Clusters for ZNF385C Gene

Zinc finger protein 385C:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF385C Gene

No ASD Table

Relevant External Links for ZNF385C Gene

GeneLoc Exon Structure for
ZNF385C
ECgene alternative splicing isoforms for
ZNF385C

Expression for ZNF385C Gene

mRNA expression in normal human tissues for ZNF385C Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZNF385C Gene

This gene is overexpressed in Testis (9.5) and Brain - Cerebellum (7.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ZNF385C Gene

SOURCE GeneReport for Unigene cluster for ZNF385C Gene Hs.443140

genes like me logo Genes that share expressions with ZNF385C: view

No data available for mRNA Expression by UniProt/SwissProt for ZNF385C Gene

Orthologs for ZNF385C Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF385C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF385C 36
  • 87 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF385C 36
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF385C 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp385c 16
Zfp385c 36
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF385C 36
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF385C 36
  • 47 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF385C 36
  • 52 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF385C 36
  • 50 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii znf385c 36
  • 40 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 17 (a)
OneToMany
Species with no ortholog for ZNF385C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF385C Gene

ENSEMBL:
Gene Tree for ZNF385C (if available)
TreeFam:
Gene Tree for ZNF385C (if available)

Paralogs for ZNF385C Gene

Paralogs for ZNF385C Gene

Selected SIMAP similar genes for ZNF385C Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF385C: view

Variants for ZNF385C Gene

Sequence variations from dbSNP and Humsavar for ZNF385C Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs4075287 -- 42,036,433(+) cacac(C/T)tgtaa intron-variant
rs4277396 -- 42,034,110(+) AATAC(A/C)GACCA intron-variant
rs4796631 -- 42,053,218(+) AGGCC(C/T)TTGCC intron-variant
rs4796760 -- 42,026,197(+) TCTCA(A/G)ACAGA utr-variant-3-prime
rs4796761 -- 42,026,356(+) TGGCT(C/T)TGCCC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF385C Gene

Variant ID Type Subtype PubMed ID
nsv908240 CNV Loss 21882294

Relevant External Links for ZNF385C Gene

HapMap Linkage Disequilibrium report
ZNF385C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF385C Gene

Disorders for ZNF385C Gene

No disorders were found for ZNF385C Gene.

No data available for UniProtKB/Swiss-Prot for ZNF385C Gene

Publications for ZNF385C Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for ZNF385C Gene

Sources for ZNF385C Gene

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