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Aliases for ZNF37A Gene

Aliases for ZNF37A Gene

  • Zinc Finger Protein 37A 2 3
  • Zinc Finger Protein 37a (KOX 21) 2 3
  • Zinc Finger Protein KOX21 3 4
  • KOX21 3 4
  • ZNF37 3 4

External Ids for ZNF37A Gene

Previous GeneCards Identifiers for ZNF37A Gene

  • GC10P038130
  • GC10P038323
  • GC10P038190
  • GC10P038387
  • GC10P038423
  • GC10P038383

Summaries for ZNF37A Gene

GeneCards Summary for ZNF37A Gene

ZNF37A (Zinc Finger Protein 37A) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF182.

UniProtKB/Swiss-Prot for ZNF37A Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF37A Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF37A Gene

Genomics for ZNF37A Gene

Regulatory Elements for ZNF37A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF37A Gene

Start:
38,094,336 bp from pter
End:
38,125,544 bp from pter
Size:
31,209 bases
Orientation:
Plus strand

Genomic View for ZNF37A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF37A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF37A Gene

Proteins for ZNF37A Gene

  • Protein details for ZNF37A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17032-ZN37A_HUMAN
    Recommended name:
    Zinc finger protein 37A
    Protein Accession:
    P17032
    Secondary Accessions:
    • B3KRQ3
    • D3DRZ3
    • Q96B88

    Protein attributes for ZNF37A Gene

    Size:
    561 amino acids
    Molecular mass:
    65418 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF37A Gene

Proteomics data for ZNF37A Gene at MOPED

Post-translational modifications for ZNF37A Gene

  • Ubiquitination at Lys409
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF37A Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF37A Gene

Domains for ZNF37A Gene

Gene Families for ZNF37A Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF37A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P17032

UniProtKB/Swiss-Prot:

ZN37A_HUMAN :
  • P17032
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF37A: view

Function for ZNF37A Gene

Molecular function for ZNF37A Gene

GENATLAS Biochemistry: zinc finger protein 37a (KOX21) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation
UniProtKB/Swiss-Prot Induction: Down-regulated in cells with DM1 (Myotonic dystrophy type 1) mutation, via a mechanism that involves abnormal control of its mRNA stability by CUGBP1.

Gene Ontology (GO) - Molecular Function for ZNF37A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity NAS 8464732
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF37A: view

Animal Model Products

CRISPR Products

miRNA for ZNF37A Gene

miRTarBase miRNAs that target ZNF37A

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF37A Gene

Localization for ZNF37A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF37A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF37A Gene COMPARTMENTS Subcellular localization image for ZNF37A gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF37A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus NAS 8464732
genes like me logo Genes that share ontologies with ZNF37A: view

Pathways for ZNF37A Gene

SuperPathways for ZNF37A Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF37A: view

Pathways by source for ZNF37A Gene

2 Reactome pathways for ZNF37A Gene

Interacting Proteins for ZNF37A Gene

Gene Ontology (GO) - Biological Process for ZNF37A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated NAS 8464732
genes like me logo Genes that share ontologies with ZNF37A: view

Transcripts for ZNF37A Gene

Unigene Clusters for ZNF37A Gene

Zinc finger protein 37A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF37A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF37A Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b
SP1: - - - -
SP2: - - - -
SP3: - -
SP4: -
SP5: - - -
SP6: - - -
SP7: - - -
SP8: - -
SP9:
SP10: -
SP11:

Relevant External Links for ZNF37A Gene

GeneLoc Exon Structure for
ZNF37A
ECgene alternative splicing isoforms for
ZNF37A

Expression for ZNF37A Gene

mRNA expression in normal human tissues for ZNF37A Gene

SOURCE GeneReport for Unigene cluster for ZNF37A Gene Hs.292575

genes like me logo Genes that share expressions with ZNF37A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF37A Gene

Orthologs for ZNF37A Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF37A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF37A 35
  • 99.47 (n)
  • 99.47 (a)
ZNF37A 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF37A 36
  • 51 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF37A 36
  • 82 (a)
OneToOne
Species with no ortholog for ZNF37A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF37A Gene

ENSEMBL:
Gene Tree for ZNF37A (if available)
TreeFam:
Gene Tree for ZNF37A (if available)

Paralogs for ZNF37A Gene

Selected SIMAP similar genes for ZNF37A Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF37A Gene

genes like me logo Genes that share paralogs with ZNF37A: view

Variants for ZNF37A Gene

Sequence variations from dbSNP and Humsavar for ZNF37A Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs176848 -- 38,092,679(+) gagtt(C/T)gagac upstream-variant-2KB
rs176849 -- 38,092,715(+) gatct(C/T)tacta upstream-variant-2KB
rs176850 -- 38,092,777(+) cttgg(A/G)acgct upstream-variant-2KB
rs176851 -- 38,092,879(+) tccat(C/T)tcaaa upstream-variant-2KB
rs176852 -- 38,093,008(+) TGATT(C/T)TTTTA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF37A Gene

Variant ID Type Subtype PubMed ID
nsv895030 CNV Loss 21882294
nsv6465 CNV Loss 18451855
esv997851 CNV Insertion 20482838
nsv895031 CNV Gain 21882294

Relevant External Links for ZNF37A Gene

HapMap Linkage Disequilibrium report
ZNF37A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF37A Gene

Disorders for ZNF37A Gene

Relevant External Links for ZNF37A

Genetic Association Database (GAD)
ZNF37A
genes like me logo Genes that share disorders with ZNF37A: view

No data available for UniProtKB/Swiss-Prot for ZNF37A Gene

Publications for ZNF37A Gene

  1. Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution. (PMID: 8464732) Tunnacliffe A. … Ponder B.A. (Nucleic Acids Res. 1993) 2 3 4 23
  2. Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering. (PMID: 2014798) Huebner K. … Thiesen H.J. (Am. J. Hum. Genet. 1991) 2 3
  3. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4
  4. Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p. (PMID: 12566394) Guy J. … Jackson M.S. (Genome Res. 2003) 3 4
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4

Products for ZNF37A Gene

Sources for ZNF37A Gene

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