ZNF37A Gene
protein-coding GIFtS: 48
GCID: GC10P038383
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zinc finger protein 37A(Previous name: zinc finger protein 37a (KOX 21) )
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Aliases for ZNF37A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 37A1 2 | | KOX211 2 3 | | ZNF371 2 3 | | Zinc Finger Protein 37a (KOX 21)1 2 | | Zinc Finger Protein KOX212 3 |
Export aliases for ZNF37A gene to outside databasesPrevious GC identifers: GC10P038130 GC10P038323 GC10P038190 GC10P038387 GC10P038423 GC10P038091 |
Summaries for ZNF37A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: ZN37A_HUMAN, P17032Function: May be involved in transcriptional regulation Gene Wiki entry for ZNF37A
|
Genomic Views for ZNF37A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_008705.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ZNF37A gene promoter: AML1a CUTL1 Nkx2-5 GATA-2 FAC1 POU2F1 POU2F1a ATF6 Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF37A
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF37A |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10p11.2 Ensembl cytogenetic band: 10p11.1 HGNC cytogenetic band: 10p11.2ZNF37A Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P038383: view genomic region
(about GC identifiers)
Start:
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38,383,264 bp from pter |
End:
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38,412,280 bp from pter |
Size:
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29,017 bases |
Orientation:
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plus strand |
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Proteins for ZNF37A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ZN37A_HUMAN, P17032 (See
protein sequence)Recommended Name: Zinc finger protein 37A Size: 561 amino acids; 65418 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: B3KRQ3 D3DRZ3 Q96B88Explore the universe of human proteins at neXtProt for ZNF37A: NX_P17032
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P17032 ZNF37A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001007095.1 NP_001171572.1 NP_003412.1 ENSEMBL proteins: ENSP00000354377 ENSP00000329141 Reactome Protein details: P17032 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table
ZNF37A for ontologies About GeneDecksing
ZNF37A Antibody Products: Assay Products for ZNF37A: |
Protein
Domains / Families for ZNF37A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF37A for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P17032ProtoNet protein and cluster: P17032 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN37A_HUMAN, P17032Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 12 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function for ZNF37A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: ZN37A_HUMAN, P17032Function: May be involved in transcriptional regulation Genatlas biochemistry entry for ZNF37A:zinc finger protein 37a (KOX21) (C2H2 type,Kruppel-like)
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF37A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF37A (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): ZNF37A (NM_003421) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF37A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF37A  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF37A |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF37A for ontologies About GeneDecksing
|
Pathways & Interactions for ZNF37A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources See GeneCards unified pathways Show all pathways
2
Reactome Pathways for ZNF37A
ZNF37A for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF37A
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
NAS | 8464732 |
ZNF37A for ontologies About GeneDecksing
|
Drugs & Compounds for ZNF37A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for ZNF37A Search CenterWatch for drugs/clinical trials and news about ZNF37A / ZN37A 
|
Transcripts for ZNF37A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ZNF37A gene (3 alternative transcripts): NM_001007094.2 NM_001178101.1 NM_003421.2 Unigene Cluster for ZNF37A: Zinc finger protein 37A Hs.292575 [show with all ESTs]Unigene Representative Sequence: BX6470896 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000498773 ENST00000361085 ENST00000479469 ENST00000463776 ENST00000477790 ENST00000351773(uc001izk.3 uc001izl.3 uc001izm.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF37A (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF37A (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): ZNF37A (NM_003421) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF37A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF37A  |
Additional cDNA sequence: AJ492195.1 AK092012.1 AK130521.1 BC015858.1 BX647089.1 X52352.1 X69115.1 7 DOTS entries: DT.442042 DT.75125693 DT.121298018 DT.40213915 DT.121298014 DT.121298032 DT.92046694 24/135 AceView cDNA sequences (see all 135): BQ771921 CA776673 AW242407 BQ694233 AA742606 AW510550 BQ001336 X69115 BU622589 AA456654 AX747310 BU677771 AA856645 AW614721 BQ574589 CA436801 AI762207 BM930123 BX382859 CD674617 CA776443 BU069920 BC015858 AK130521 GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF37A (see all 11) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | |
| SP1: | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ZNF37A
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Expression for ZNF37A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF37A expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TACCCCATAA
About this image See ZNF37A Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ZNF37A
SOURCE GeneReport for Unigene cluster: Hs.292575 SABiosciences Custom PCR Arrays for ZNF37A
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF37A Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF37A | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF37A | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF37A | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF37A |
Orthologs for ZNF37A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF37A gene from 1/7 species (see all 7) About this table
ENSEMBL Gene Tree for ZNF37A (if available) TreeFam Gene Tree for ZNF37A (if available)  |
Paralogs for ZNF37A gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ZNF37A gene
- ZNF3342 ENSG000002673602 ZNF7822 ZNF122 ZNF5102 ZNF5672 ZNF33A2 ZNF7172
- RBAK2 ZNF487P2 ZNF2482 ZNF33B2 ZNF3822
18/439 SIMAP similar genes for ZNF37A using alignment to 1 protein entry: ZN37A_HUMAN(see all similar genes):DKFZp313M0722 DKFZp686H10254 ZSCAN21 ZNF323 DKFZp686N14223 ZNF3 DKFZp666C237 DKFZp762K012 HZF30 HZF36 ZNF146 ZNF696 ZNF702P ZNF79 ZSCAN22 ZNF250 ZKSCAN1 ZNF32
ZNF37A for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ZNF37A PGOHUM00000238431 PGOHUM00000240622
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Genomic Variants for ZNF37A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 10 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
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HapMap Linkage Disequilibrium report for ZNF37A (38383264 - 38412280 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ZNF37A: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF37A |
|
Disorders
/ Diseases for ZNF37A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications for ZNF37A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF37A gene integrated from 9 sources: (articles sorted by number of sources associating them with ZNF37A) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution. (PubMed id 8464732)1, 2, 3, 9 Tunnacliffe A.... Ponder B.A. (1993)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p. (PubMed id 12566394)1, 2 Guy J....Jackson M.S. (2003)
- Twenty-seven nonoverlapping zinc finger cDNAs from hu man T cells map to nine different chromosomes with apparent clustering. (PubMed id 2014798)1, 3 Huebner K....Thiesen H.J. (1991)
- Multiple genes encoding zinc finger domains are expressed in human T cells. (PubMed id 2288909)1, 2 Thiesen H.-J. (1990)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF37A gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ZNF37A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF37A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF37A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ZNF37A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF37A gene: Search GeneIP for patents involving ZNF37A
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ZNF37A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF37A | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF37A | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF37A | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF37A | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF37A | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF37A |
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| | | Search Tocris compounds for ZNF37A |
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 | | ZNF37A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF37A |
|  |  |  | | | Search ThermoFisher Antibodies for ZNF37A |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF37A |
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