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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ZNF367 Gene

protein-coding GIFtS: 40
GCID: GC09M099148

zinc finger protein 367

Search for ZNF367
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Zinc Finger Protein 367¹ ²		CDC14B²
ZFF29² ³		C2H2 Zinc Finger Protein ZFF29a²
C2H2 Zinc Finger Protein ZFF29² ³		CDC14 Cell Division Cycle 14 Homolog B²
FLJ33970¹

External Ids:	HGNC: 18320¹	Entrez Gene: 195828²	Ensembl: ENSG00000165244⁷	OMIM: 610160⁵	UniProtKB: Q7RTV3³

Export aliases for ZNF367 gene to outside databases

Previous GC identifers: GC09U990216 GC09M090891 GC09M092605 GC09M094530 GC09M094528 GC09M096229 GC09M098188 GC09M068759

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZN367_HUMAN, Q7RTV3

Function: Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000009.11 NC_018920.1 NT_008470.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ZNF367 gene promoter:
HOXA9 GATA-3 p53 MyoD AP-4 Nkx2-5 GATA-2 GATA-1 HOXA5
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZNF367 promoter sequence

Search SABiosciences Chromatin IP Primers for ZNF367

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF367

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22|9q22.32 Ensembl cytogenetic band: 9q22.32 HGNC cytogenetic band: 9q22

ZNF367 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF367 gene location

GeneLoc information about chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09M099148: view genomic region (about GC identifiers)

Start:	99,148,223 bp from pter	End:	99,180,669 bp from pter
Size:	32,447 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ZN367_HUMAN, Q7RTV3 (See protein sequence)

Recommended Name: Zinc finger protein 367

Size: 350 amino acids; 38411 Da

Subcellular location: Nucleus

Secondary accessions: Q6Q7C8

Alternative splicing: 2 isoforms: Q7RTV3-1 Q7RTV3-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZNF367: NX_Q7RTV3

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q7RTV3

ZNF367 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_710162.1

ENSEMBL proteins:

ENSP00000364405

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Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005730	NOT nucleolus	IDA	--
GO:0005737	cytoplasm	IDA	--

ZNF367 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZNF367 for domains About GeneDecksing

3 InterPro domains/families:

IPR015880 Znf_C2H2-like

IPR013087 Znf_C2H2/integrase_DNA-bd

IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q7RTV3

ProtoNet protein and cluster: Q7RTV3

UniProtKB/Swiss-Prot: ZN367_HUMAN, Q7RTV3

Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family

Similarity: Contains 2 C2H2-type zinc fingers

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ZN367_HUMAN, Q7RTV3

Function: Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes

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Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0003700	sequence-specific DNA binding transcription factor activity	IDA	15344908
GO:0008270	zinc ion binding	IEA	--

ZNF367 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ZNF367

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0006357	regulation of transcription from RNA polymerase II promoter	IDA	15344908

ZNF367 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZNF367
Search CenterWatch for drugs/clinical trials and news about ZNF367 / ZN367

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
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About This Section

REFSEQ mRNAs for ZNF367 gene:

NM_153695.3

Unigene Cluster for ZNF367:

Zinc finger protein 367

Hs.494557 [show with all ESTs]

Unigene Representative Sequence: NM_153695

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000375256(uc004awf.3 uc004awg.3)

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		hsa-miR-520e hsa-miR-302d hsa-miR-520f hsa-miR-4272 hsa-miR-146a hsa-miR-106a hsa-miR-15a hsa-miR-503

		SwitchGear 3'UTR luciferase reporter plasmid: ZNF367 3' UTR sequence

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Additional cDNA sequence:

AK091289.1 AY554164.1 AY554165.1 BC126141.1

2 DOTS entries:

DT.40113051 DT.99939890

3 AceView cDNA sequences:

BU428803 AW500732 CF138198

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZNF367 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGTAATTTT

About this image
See ZNF367 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF367

SOURCE GeneReport for Unigene cluster: Hs.494557

SABiosciences Custom PCR Arrays for ZNF367

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for ZNF367 gene from 5/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	LOC100858851¹	zinc finger protein 367-like	74.5(n) 80.56(a)		100858851 XM_003643009.1 XP_003643057.1
lizard (Anolis carolinensis)	Reptilia	ZNF367⁶	--	71(a)	1 ↔ 1	2(39980014-39986037)
African clawed frog (Xenopus laevis)	Amphibia	Xl.33054²	Xenopus laevis transcribed sequence with weak similarity more	79.5(n)		BJ638860.1
zebrafish (Danio rerio)	Actinopterygii	znf367¹	zinc finger protein 367	71.16(n) 78.2(a)		550421 NM_001017726.1 NP_001017726.1
honey bee (Apis mellifera)	Insecta	--	--	26(a)	1 → many	GroupUn.402(17945-20623)

ENSEMBL Gene Tree for ZNF367 (if available)
TreeFam Gene Tree for ZNF367 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs148174352^1,2		--	99147999(+)	`CCCGAC/TGAGGA`	1	--	int¹		0	--	--	--	--
rs142940723^1,2		--	99148029(+)	`TAAAAG/TCCATA`	1	--	int¹		0	--	--	--	--
rs10820507^1,2	C,F,A,H,	--	99148152(+)	`TTTTTA/GTATCA`	1	--	int¹		16		NS EA NA WA	2338
rs185408602^1,2		--	99148443(+)	`AAAAGA/GACATT`	1	--	ut3¹		0	--	--	--	--
rs35719967^1,2	C,F,	--	99148467(+)	`AATAGT/ATGTGA`	1	--	ut3¹		7		NA WA	310
rs78867483^1,2	F,	--	99148640(+)	`ACTACC/TCTTCC`	1	--	ut3¹		1		WA	118
rs118047818^1,2	F,	--	99148649(+)	`CCTTCT/CTTAGT`	1	--	ut3¹		1		NA	120
rs191241730^1,2		--	99148698(+)	`TGTTGC/TTTTTA`	1	--	ut3¹		0	--	--	--	--
rs183043541^1,2		--	99148699(+)	`GTTGTG/TTTTAG`	1	--	ut3¹		0	--	--	--	--
rs186730452^1,2		--	99148838(+)	`ATTACA/GAAAAA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZNF367 (99148223 - 99180669 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF367: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ZNF367 for disorders About MalaCards

ZNF367 for disorders About GeneDecksing

OMIM gene information: 610160 OMIM disorders: --

Export disorders for ZNF367 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ZNF367 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with ZNF367)

Utopia: connect your pdf to the dynamic
world of online information

Molecular cloning and characterization of ZFF29: a protein containing a unique Cys2His2 zinc-finger motif. (PubMed id 15344908)^{1, 2, 9} Asano H.... Stamatoyannopoulos G. (2004)
Fugu and human sequence comparison identifies novel human genes and conserved non-coding sequences. (PubMed id 12234665)^{1, 2} Gilligan P.... Venkatesh B. (2002)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)² Humphray S.J.... Dunham I. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair. (PubMed id 20479464)⁹ Mocciaro A....Schiebel E. (2010)
A single-copy suppressor of the Saccharomyces cerevisae late-mitotic mutants cdc15 and dbf2 is encoded by the Candida albicans CDC14 gene. (PubMed id 11427967)⁹ Jimenez J....Sanchez M. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 195828	HGNC: 18320	AceView: ZNF367.1	Ensembl:ENSG00000165244	euGenes: HUgn195828
ECgene: ZNF367	H-InvDB: ZNF367

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ZNF367	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ZNF367 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for ZNF367 gene:
Search GeneIP for patents involving ZNF367

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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About This Section


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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes ZNF367 gene at Home site.

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ZNF367 Gene

zinc finger protein 367

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ZNF367 Gene

zinc finger protein 367

Aliasesfor ZNF367 gene

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for ZNF367 gene

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for ZNF367 gene

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