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ZNF365 Gene

protein-coding   GIFtS: 53
GCID: GC10P064133

Zinc Finger Protein 365

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 3651 2     ZNF365D2
Protein Su482 3     Protein ZNF3652
UAN2 5     talanin2
Talanin1     KIAA08443
Su482     

External Ids:    HGNC: 181941   Entrez Gene: 228912   Ensembl: ENSG000001383117   OMIM: 6078185   UniProtKB: Q70YC43   
UniProtKB: Q70YC53   

Export aliases for ZNF365 gene to outside databases

Previous GC identifers: GC10P064026 GC10P063478 GC10P063803 GC10P058125


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZNF365 Gene:
This gene encodes several isoforms which have different expression patterns and functions. Mutation in this gene
is associated with uric acid nephrolithiasis (UAN). Alternatively spliced variants, encoding distinct proteins,
have been identified. (provided by RefSeq, May 2010)

GeneCards Summary for ZNF365 Gene:
ZNF365 (zinc finger protein 365) is a protein-coding gene. Diseases associated with ZNF365 include acute urate nephropathy, and narcolepsy 1. An important paralog of this gene is FBXO41.

UniProtKB/Swiss-Prot: TALAN_HUMAN, Q70YC4
Function: May play a role in uric acid excretion

Gene Wiki entry for ZNF365 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF365 gene promoter:
         STAT1   Elk-1   AML1a   Pax-5   NCX/Ncx   STAT1alpha   PPAR-gamma1   SRY   PPAR-gamma2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF365 promoter sequence
   Search Chromatin IP Primers for ZNF365

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF365


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q21.2   Ensembl cytogenetic band:  10q21.2   HGNC cytogenetic band: 10q21.2

ZNF365 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF365 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P064133:  view genomic region     (about GC identifiers)

Start:
64,133,916 bp from pter      End:
64,431,771 bp from pter
Size:
297,856 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TALAN_HUMAN, Q70YC4 (See protein sequence)
Recommended Name: Talanin  
Size: 216 amino acids; 24036 Da
Miscellaneous: Isoform 4 (talanin) of ZNF365 does not exist in rodents. In primates, a canonical intron-exon
structure exist, with several stop codons preventing talanin production in old world and new world monkeys. It
seems therefore that isoform 4 transcript emerged during primate evolution from a noncoding genomic sequence
Alternative splicing: 6 isoforms:  Q70YC4-1   Q70YC5-1   Q70YC5-2   Q70YC5-3   Q70YC5-4   Q70YC5-5   (No experimental confirmation available)

UniProtKB/Swiss-Prot: ZN365_HUMAN, Q70YC5 (See protein sequence)

Recommended Name: Protein ZNF365  
Size: 407 amino acids; 46542 Da
Subunit: Homodimer. Interacts with NDE1 and NDEL1. Does not interact with TUBG1
Sequence caution: Sequence=AAH17841.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence; Sequence=BAA74867.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8K0F0 O94930 Q05D75 Q5HYE6 Q68SG8 Q6NSK2 Q6P9D4 Q70YC6 Q70YC7
Alternative splicing: 6 isoforms:  Q70YC5-1   Q70YC5-2   Q70YC5-3   Q70YC5-4   Q70YC5-5   Q70YC4-1   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZNF365: NX_Q70YC5

Explore proteomics data for ZNF365 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF365 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_055766.2  NP_955522.1  NP_955523.1  NP_955524.3  

    ENSEMBL proteins: 
     ENSP00000378674   ENSP00000378675   ENSP00000387091   ENSP00000392791   ENSP00000378672  
     ENSP00000378670   ENSP00000362889   ENSP00000345300  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    1 InterPro protein domain:
     IPR015880 Znf_C2H2-like

    Graphical View of Domain Structure for InterPro Entry Q70YC4
    Graphical View of Domain Structure for InterPro Entry Q70YC5

    ProtoNet protein and cluster: Q70YC4


    ZNF365 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TALAN_HUMAN, Q70YC4
    Function: May play a role in uric acid excretion

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16682949
         
    ZNF365 for ontologies           About GeneDecksing


    Animal Models:
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    Block miRNA regulation of human, mouse, rat ZNF365 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZNF365 (see all 31):
    hsa-miR-194* hsa-miR-323-3p hsa-miR-875-3p hsa-miR-193a-3p hsa-miR-607 hsa-miR-496 hsa-miR-3138 hsa-miR-550a*
    SwitchGear 3'UTR luciferase reporter plasmidZNF365 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN365_HUMAN, Q70YC5: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=localizes to the
    centrosome at all stages of the cell cycle
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol2
    nucleus2
    extracellular1
    golgi apparatus1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005815microtubule organizing center IEA--

    ZNF365 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF365
    Interactions:

        GeneGlobe Interaction Network for ZNF365

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for ZNF365 (Q70YC51, 3 ENSP000003870914) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NDE1Q9NXR11, 3, ENSP000003458924EBI-941182,EBI-941227 I2D: score=2 STRING: ENSP00000345892
    DISC1Q9NRI53, ENSP000003555964I2D: score=2 STRING: ENSP00000355596
    NDEL1Q9GZM83, ENSP000003339824I2D: score=1 STRING: ENSP00000333982
    --ENSP000003936424STRING: ENSP00000393642
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF365 (ZN365)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZNF365 gene (4 alternative transcripts): 
    NM_014951.2  NM_199450.2  NM_199451.2  NM_199452.3  

    Unigene Cluster for ZNF365:

    Zinc finger protein 365
    Hs.22653  [show with all ESTs]
    Unigene Representative Sequence: NM_014951
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000395254(uc001jly.4 uc001jlz.4 uc001jma.4) ENST00000395255(uc001jmb.4)
    ENST00000410046(uc001jmc.2) ENST00000466727 ENST00000421210 ENST00000395251(uc001jmd.1 uc001jme.1 uc001jmf.1 uc009xpg.1)
    ENST00000395249 ENST00000373784 ENST00000344640 ENST00000461412
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ZNF365 (see all 31):
    hsa-miR-194* hsa-miR-323-3p hsa-miR-875-3p hsa-miR-193a-3p hsa-miR-607 hsa-miR-496 hsa-miR-3138 hsa-miR-550a*
    SwitchGear 3'UTR luciferase reporter plasmidZNF365 3' UTR sequence
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    Additional mRNA sequence: 

    AB020651.1 AJ505147.1 AJ505148.1 AJ505149.1 AJ505150.1 AK289515.1 AK289808.1 BC017841.1 
    BC035049.1 BC044306.1 BC060817.1 BC070073.1 BC101082.1 BC101083.1 BC101084.1 BC101085.2 
    BC128394.1 BX647853.1 BX647904.1 

    6 DOTS entries:

    DT.408480  DT.99965742  DT.102824808  DT.100691106  DT.100667711  DT.91816223 

    Selected AceView cDNA sequences (see all 43):

    BC017841 NM_199452 BF512570 AJ505150 BI914007 CB118047 BQ899124 CA438693 
    AI474945 BI822044 BC035049 AJ505149 BC044306 NM_199451 BC070073 BQ340495 
    AA846150 AJ505148 AB020651 BU955165 NM_199450 BC060817 BU154984 BX647853 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF365    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
    SP1:                                                  -                                       
    SP2:                          -           -     -           -     -     -                     
    SP3:                          -                                                               
    SP4:                                                                                          
    SP5:                                                                                          


    ECgene alternative splicing isoforms for ZNF365

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF365 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAACTGAAT
    ZNF365 Expression
    About this image


    ZNF365 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Oligodendrocyte Precursor Cells Forebrain White Matter
             Thalamus
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             HyStem+TGFbeta3+GDF5-induced MEL2 cells
     
     Adipose (Muscoskeletal System)
             Visceral White Adipocytes Visceral White Adipose
     
     Cartilage (Muscoskeletal System)
             HyStem+TGFbeta3+GDF5-induced MEL2 cells
    ZNF365 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF365 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.22653

    UniProtKB/Swiss-Prot: TALAN_HUMAN, Q70YC4
    Tissue specificity: Isoform 4 is expressed in placenta, lung, kidney and pancreas

    UniProtKB/Swiss-Prot: ZN365_HUMAN, Q70YC5
    Tissue specificity: Isoform 1 is expressed in brain. Isoform 2 is expressed in placenta and at low level in lung
    and liver. Isoform 3 is expressed in kidney and pancreas

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF365

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZNF365 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp3651 , 5 zinc finger protein 3651, 5 83.46(n)1
    85.01(a)1
      10 (35.04 cM)5
    2160491  NM_178679.21  NP_848794.11 
     678861035 
    chicken
    (Gallus gallus)
    Aves ZNF3651 zinc finger protein 365 64.33(n)
    61.04(a)
      423658  NM_001199547.1  NP_001186476.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZNF3656
    zinc finger protein 365
    56(a)
    1 ↔ 1
    GL343204.1(2893149-2925520)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.197682 Xenopus laevis transcribed sequence with weak similarity more 77.02(n)    BQ398814.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7993201 protein ZNF365-like 51.73(n)
    44.81(a)
      799320  XM_001339655.2  XP_001339691.1 


    ENSEMBL Gene Tree for ZNF365 (if available)
    TreeFam Gene Tree for ZNF365 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF365 gene
    FBXO412  

    ZNF365 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Polymorphic Variants from UniProtKB/Swiss-Prot
    TALAN_HUMAN, Q70YC4: Thr-62 is associated with increased risk for uric acid nephrolithiasis


    Selected SNPs for ZNF365 (see all 6272)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs70761561,2,,4
    C,F,A,Hother164788009(+) ATCTCG/ACCTTC 3 /T /A mis1 int1 ese334Minor allele frequency- A:0.17NS EA NA WA CSA EU 8745
    rs1385901561,2
    C--58135720(+) TGGCC-/TTTTTT 3 -- int10--------
    rs23938761,2
    --58141051(+) gttttG/Tttttt 3 -- int10--------
    rs595517081,2
    C--58141051(+) TTTTTTT/-ACTGC 3 -- int11Minor allele frequency- -:0.50NA 2
    rs57855211,2
    C,F--58153091(+) TTTATG/-GGGGG 3 -- int1 ut313Minor allele frequency- -:0.50NA CSA 6
    rs354359891,2
    C--58155730(+) GATGGAA/-AAGAG 2 -- int12Minor allele frequency- -:0.25NA CSA 4
    rs107616311,2
    C,F,A--58166621(+) ATTTTG/CGTCTG 2 -- int16Minor allele frequency- C:0.37WA NA EA 364
    rs107400771,2
    C,F,A,H--58166622(+) TTTTCA/GTCTGA 2 -- int16Minor allele frequency- G:0.37WA NA EA 364
    rs626833601,2
    C--58167817(+) CTTAA-/GCTTCT 2 -- int10--------
    rs345912841,2
    C--58169268(+) CTGTC-/T/TT  
            
    TTTTT
    2 -- int12NA CSA 4

    HapMap Linkage Disequilibrium report for ZNF365 (64133916 - 64383916 bp, first 250kb of ZNF365)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for ZNF365:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2677528CNV Deletion23128226
    esv2670021CNV Deletion23128226
    esv271402CNV Insertion20981092
    esv29409CNV Loss19812545
    esv33660CNV Loss17666407
    nsv825408CNV Loss20364138
    esv34099CNV Loss18971310
    nsv831891CNV Gain17160897
    nsv8681CNV Gain18304495
    nsv467293CNV Gain19166990

    Human Gene Mutation Database (HGMD): ZNF365
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF365
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF365

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607818   
    OMIM disorders: 605990  
    UniProtKB/Swiss-Prot: ZN365_HUMAN, Q70YC5
  • Uric acid nephrolithiasis (UAN) [MIM:605990]: A form of nephrolithiasis, a common multifactorial disease
    characterized by stones formation in the kidney and urinary tract. Nephrolithiasis is due to supersaturation of
    the urine by stone-forming constituents, including calcium, oxalate and uric acid. Crystals or foreign bodies can
    act as nidi, upon which ions from the supersaturated urine form microscopic crystalline structures. Uric acid
    nephrolithiasis occurs when the urine becomes overly concentrated with uric acid and accounts for 20% of all
    stones. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry

  • 17 diseases for ZNF365:    
    About MalaCards
    acute urate nephropathy    narcolepsy 1    nephrolithiasis    spondylitis
    ankylosing spondylitis    crohn's disease    atopic dermatitis    bipolar disorder
    dermatitis    inflammatory bowel disease    sarcoma    schizophrenia
    ovarian cancer    alzheimer's disease    breast cancer    multiple myeloma
    myeloma

    1 disease from the University of Copenhagen DISEASES database for ZNF365:
    Acute urate nephropathy

    ZNF365 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZNF365
    Human Genome Epidemiology (HuGE) Navigator: ZNF365 (10 documents)

    Export disorders for ZNF365 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF365 gene, integrated from 10 sources (see all 41):
    (articles sorted by number of sources associating them with ZNF365)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel gene and a common variant associated with uric acid nephrolithiasis in a Sardinian genetic isolate. (PubMed id 12740763)1, 2, 3 Gianfrancesco F.... Pirastu M. (Am. J. Hum. Genet. 2003)
    2. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1998)
    3. Emergence of talanin protein associated with human uric acid nephrolithiasis in the hominidae lineage. (PubMed id 15363853)1, 2, 9 Gianfrancesco F....Parastu M. (Gene 2004)
    4. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. (PubMed id 22412388)1, 4 Kenny E.E....Peter I. (PLoS Genet. 2012)
    5. Genome-wide association study of intelligence: additive effects of novel brain expressed genes. (PubMed id 22449649)1, 4 Loo S.K....Nelson S.F. (J Am Acad Child Adolesc Psychiatry 2012)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    7. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. (PubMed id 21102463)1, 4 Franke A....Parkes M. (Nat. Genet. 2010)
    8. Susceptibility loci reported in genome-wide association studies are associated with Crohn's disease in Canadian children. (PubMed id 20222910)1, 4 Amre D.K....Levy E. (amp 2010)
    9. Analysis of 39 Crohn's disease risk loci in Swedish inflammatory bowel disease patients. (PubMed id 19760754)1, 4 TAPrkvist L....Pettersson S. (Inflamm. Bowel Dis. 2010)
    10. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. (PubMed id 18587394)1, 4 Barrett J.C....Daly M.J. (Nat. Genet. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 22891 HGNC: 18194 AceView: ZNF365 Ensembl:ENSG00000138311 euGenes: HUgn22891
    ECgene: ZNF365 H-InvDB: ZNF365

    (According to HUGE)
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    HUGE: KIAA0844

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ZNF365 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for ZNF365 gene:
    Search GeneIP for patents involving ZNF365

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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