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Aliases for ZNF362 Gene

Aliases for ZNF362 Gene

  • Zinc Finger Protein 362 2 3 5
  • Rotund Homolog (Drosophila) 2
  • Rotund Homolog 3
  • Lin-29 3
  • RN 3

External Ids for ZNF362 Gene

Previous GeneCards Identifiers for ZNF362 Gene

  • GC00U991155
  • GC01P033494
  • GC01P033722
  • GC01P031852

Summaries for ZNF362 Gene

GeneCards Summary for ZNF362 Gene

ZNF362 (Zinc Finger Protein 362) is a Protein Coding gene. An important paralog of this gene is ZNF384.

UniProtKB/Swiss-Prot for ZNF362 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF362 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF362 Gene

Genomics for ZNF362 Gene

Regulatory Elements for ZNF362 Gene

Enhancers for ZNF362 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H032262 1.8 FANTOM5 Ensembl ENCODE dbSUPER 38.1 -990.9 -990920 4 ZNF493 ZFP64 RARA SCRT2 ZNF654 ZNF680 ZC3H11A CEBPB OVOL3 REST TXLNA RBBP4 KHDRBS1 SNRNP40 TMEM39B ZBTB8A ZNF362 DCDC2B TSSK3 S100PBP
GH01H032271 1.5 Ensembl ENCODE dbSUPER 19.3 -982.8 -982758 5 ZNF493 ZNF133 GLI4 ETS1 ZNF121 GLIS2 SP3 YY2 NCOA1 SMARCA4 RBBP4 ZBTB8A TXLNA KHDRBS1 IQCC SNRNP40 S100PBP ZBTB8B ENSG00000224066 ZNF362
GH01H033361 2.3 VISTA FANTOM5 Ensembl ENCODE dbSUPER 12.5 +108.4 108395 7 PKNOX1 ATF1 ZNF493 ZFP64 ZNF133 ARID4B FEZF1 ZNF2 TCF12 ZNF766 ZBTB8A RBBP4 ZSCAN20 S100PBP BSDC1 PHC2 CSMD2-AS1 ZBTB8B ZNF362 CSMD2
GH01H033458 1.4 Ensembl ENCODE dbSUPER 19.5 +202.3 202349 0 TBL1XR1 ZFP64 BATF ZNF366 FOS ATF7 KLF7 RUNX3 IKZF2 ZNF654 RBBP4 ZSCAN20 S100PBP ZBTB8A ZNF362 ENSG00000270115 ZBTB8B PHC2 AK2 AZIN2
GH01H032813 1.7 FANTOM5 ENCODE dbSUPER 12.4 -439.1 -439066 7 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC ZC3H11A RBBP4 KHDRBS1 ZBTB8A TXLNA TMEM39B S100PBP KPNA6 ZSCAN20 TSSK3 FAM229A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF362 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF362 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000004487 293 2401 PKNOX1 FOXA2 ARID4B SIN3A FEZF1 DMAP1 YY1 GLIS2 FOS SP3

Genomic Location for ZNF362 Gene

Chromosome:
1
Start:
33,256,307 bp from pter
End:
33,300,720 bp from pter
Size:
44,414 bases
Orientation:
Plus strand

Genomic View for ZNF362 Gene

Genes around ZNF362 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF362 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF362 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF362 Gene

Proteins for ZNF362 Gene

  • Protein details for ZNF362 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T0B9-ZN362_HUMAN
    Recommended name:
    Zinc finger protein 362
    Protein Accession:
    Q5T0B9
    Secondary Accessions:
    • Q8WYU4

    Protein attributes for ZNF362 Gene

    Size:
    420 amino acids
    Molecular mass:
    45814 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF362 Gene

Post-translational modifications for ZNF362 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF362 Gene

No data available for DME Specific Peptides for ZNF362 Gene

Domains & Families for ZNF362 Gene

Gene Families for ZNF362 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF362 Gene

Suggested Antigen Peptide Sequences for ZNF362 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5T0B9

UniProtKB/Swiss-Prot:

ZN362_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF362: view

Function for ZNF362 Gene

Molecular function for ZNF362 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF362 Gene

Gene Ontology (GO) - Molecular Function for ZNF362 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF362: view
genes like me logo Genes that share phenotypes with ZNF362: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ZNF362
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF362 Gene

Localization for ZNF362 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF362 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF362 gene
Compartment Confidence
nucleus 5

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF362 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF362: view

Pathways & Interactions for ZNF362 Gene

SuperPathways for ZNF362 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF362 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF362: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF362 Gene

Drugs & Compounds for ZNF362 Gene

No Compound Related Data Available

Transcripts for ZNF362 Gene

Unigene Clusters for ZNF362 Gene

Zinc finger protein 362:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ZNF362
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF362 Gene

No ASD Table

Relevant External Links for ZNF362 Gene

GeneLoc Exon Structure for
ZNF362
ECgene alternative splicing isoforms for
ZNF362

Expression for ZNF362 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF362 Gene

Protein differential expression in normal tissues from HIPED for ZNF362 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (25.5), Tlymphocyte (11.7), Placenta (8.5), Fetal testis (8.5), and Fetal Brain (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF362 Gene



Protein tissue co-expression partners for ZNF362 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF362 Gene:

ZNF362

SOURCE GeneReport for Unigene cluster for ZNF362 Gene:

Hs.743358

Evidence on tissue expression from TISSUES for ZNF362 Gene

  • Nervous system(4.3)
  • Liver(4.1)
genes like me logo Genes that share expression patterns with ZNF362: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF362 Gene

Orthologs for ZNF362 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF362 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF362 33 34
  • 99.84 (n)
dog
(Canis familiaris)
Mammalia ZNF362 33 34
  • 95.19 (n)
cow
(Bos Taurus)
Mammalia ZNF362 33 34
  • 94.63 (n)
rat
(Rattus norvegicus)
Mammalia Zfp362 33
  • 92.82 (n)
mouse
(Mus musculus)
Mammalia Zfp362 33 16 34
  • 91.63 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF362 34
  • 76 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF362 33 34
  • 86.57 (n)
lizard
(Anolis carolinensis)
Reptilia ZNF362 34
  • 93 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf362 33
  • 80.81 (n)
zebrafish
(Danio rerio)
Actinopterygii znf362b 33 34
  • 73.32 (n)
znf362a 34
  • 70 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta sqz 34
  • 21 (a)
ManyToMany
rn 34
  • 16 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea lin-29 34
  • 23 (a)
OneToMany
Species where no ortholog for ZNF362 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZNF362 Gene

ENSEMBL:
Gene Tree for ZNF362 (if available)
TreeFam:
Gene Tree for ZNF362 (if available)

Paralogs for ZNF362 Gene

Variants for ZNF362 Gene

Sequence variations from dbSNP and Humsavar for ZNF362 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000067945 -- 33,287,141(+) GATTT(A/C)TAGAG intron-variant
rs1000068851 -- 33,280,536(+) AGCAG(C/T)GGGGC intron-variant
rs1000109418 -- 33,272,033(+) TGAGG(C/G)TGGTG intron-variant
rs1000177490 -- 33,295,571(+) CTCAC(A/G)GCAGT intron-variant
rs1000190113 -- 33,286,928(+) GTAGA(A/G)TTAGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF362 Gene

Variant ID Type Subtype PubMed ID
nsv1112530 CNV deletion 24896259
nsv522364 CNV loss 19592680
nsv524709 CNV loss 19592680
nsv545963 CNV loss 21841781

Variation tolerance for ZNF362 Gene

Residual Variation Intolerance Score: 25.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.14; 23.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF362 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF362

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF362 Gene

Disorders for ZNF362 Gene

Relevant External Links for ZNF362

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF362

No disorders were found for ZNF362 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF362 Gene

Publications for ZNF362 Gene

  1. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 60
  2. Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. (PMID: 27880917) St-Denis N … Gingras AC (Cell reports 2016) 3 60
  3. SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage. (PMID: 25772364) Hendriks IA … Vertegaal AC (Cell reports 2015) 4 60
  4. Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. (PMID: 25281560) Lambert JP … Gingras AC (Journal of proteomics 2015) 3 60
  5. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks IA … Vertegaal AC (Nature structural & molecular biology 2014) 4 60

Products for ZNF362 Gene

Sources for ZNF362 Gene

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