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Aliases for ZNF362 Gene

Aliases for ZNF362 Gene

  • Zinc Finger Protein 362 2 3
  • Rotund Homolog (Drosophila) 2
  • Rotund Homolog 3
  • Lin-29 3
  • RN 3

External Ids for ZNF362 Gene

Previous GeneCards Identifiers for ZNF362 Gene

  • GC00U991155
  • GC01P033494
  • GC01P033722
  • GC01P031852

Summaries for ZNF362 Gene

GeneCards Summary for ZNF362 Gene

ZNF362 (Zinc Finger Protein 362) is a Protein Coding gene. An important paralog of this gene is ZNF524.

UniProtKB/Swiss-Prot for ZNF362 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF362 Gene

Genomics for ZNF362 Gene

Regulatory Elements for ZNF362 Gene

Genomic Location for ZNF362 Gene

Chromosome:
1
Start:
33,256,307 bp from pter
End:
33,300,720 bp from pter
Size:
44,414 bases
Orientation:
Plus strand

Genomic View for ZNF362 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF362 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF362 Gene

Proteins for ZNF362 Gene

  • Protein details for ZNF362 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T0B9-ZN362_HUMAN
    Recommended name:
    Zinc finger protein 362
    Protein Accession:
    Q5T0B9
    Secondary Accessions:
    • Q8WYU4

    Protein attributes for ZNF362 Gene

    Size:
    420 amino acids
    Molecular mass:
    45814 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF362 Gene

Proteomics data for ZNF362 Gene at MOPED

Post-translational modifications for ZNF362 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF362 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF362 Gene

Domains & Families for ZNF362 Gene

Gene Families for ZNF362 Gene

Protein Domains for ZNF362 Gene

Suggested Antigen Peptide Sequences for ZNF362 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5T0B9

UniProtKB/Swiss-Prot:

ZN362_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 6 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 6 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF362: view

Function for ZNF362 Gene

Molecular function for ZNF362 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF362 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF362: view
genes like me logo Genes that share phenotypes with ZNF362: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF362

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF362 Gene

Localization for ZNF362 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF362 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF362 Gene COMPARTMENTS Subcellular localization image for ZNF362 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF362 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF362: view

Pathways & Interactions for ZNF362 Gene

SuperPathways for ZNF362 Gene

No Data Available

Interacting Proteins for ZNF362 Gene

Gene Ontology (GO) - Biological Process for ZNF362 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF362: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF362 Gene

Drugs & Compounds for ZNF362 Gene

No Compound Related Data Available

Transcripts for ZNF362 Gene

Unigene Clusters for ZNF362 Gene

Zinc finger protein 362:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF362

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF362 Gene

No ASD Table

Relevant External Links for ZNF362 Gene

GeneLoc Exon Structure for
ZNF362
ECgene alternative splicing isoforms for
ZNF362

Expression for ZNF362 Gene

mRNA expression in normal human tissues for ZNF362 Gene

Protein differential expression in normal tissues from HIPED for ZNF362 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (25.5), Tlymphocyte (11.7), Placenta (8.5), Fetal testis (8.5), and Fetal Brain (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF362 Gene



SOURCE GeneReport for Unigene cluster for ZNF362 Gene Hs.743358

genes like me logo Genes that share expression patterns with ZNF362: view

Protein tissue co-expression partners for ZNF362 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF362 Gene

Orthologs for ZNF362 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF362 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF362 35
  • 94.63 (n)
  • 97.36 (a)
ZNF362 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF362 35
  • 95.19 (n)
  • 98.08 (a)
ZNF362 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp362 35
  • 91.63 (n)
  • 96.65 (a)
Zfp362 16
Zfp362 36
  • 99 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF362 35
  • 99.84 (n)
  • 100 (a)
ZNF362 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp362 35
  • 92.82 (n)
  • 96.65 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF362 36
  • 76 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF362 35
  • 86.57 (n)
  • 93.53 (a)
ZNF362 36
  • 94 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF362 36
  • 93 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf362 35
  • 80.81 (n)
  • 89.08 (a)
zebrafish
(Danio rerio)
Actinopterygii znf362b 35
  • 73.32 (n)
  • 80.56 (a)
znf362a 36
  • 70 (a)
OneToMany
znf362b 36
  • 73 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta rn 36
  • 16 (a)
ManyToMany
sqz 36
  • 21 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea lin-29 36
  • 23 (a)
OneToMany
Species with no ortholog for ZNF362:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZNF362 Gene

ENSEMBL:
Gene Tree for ZNF362 (if available)
TreeFam:
Gene Tree for ZNF362 (if available)

Paralogs for ZNF362 Gene

Paralogs for ZNF362 Gene

genes like me logo Genes that share paralogs with ZNF362: view

Variants for ZNF362 Gene

Sequence variations from dbSNP and Humsavar for ZNF362 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1132789 -- 33,299,676(-) CTCTC(A/G)TTTCT utr-variant-3-prime
rs1132790 -- 33,299,671(-) GTTTC(C/T)GCCTC utr-variant-3-prime
rs3935892 -- 33,271,825(+) CTGGG(A/C)AGATG intron-variant
rs4077439 -- 33,269,760(+) TGGCC(A/G)TAAGT intron-variant, utr-variant-5-prime
rs4132073 -- 33,257,610(+) AACTG(A/G)GAAAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF362 Gene

Variant ID Type Subtype PubMed ID
nsv524709 CNV Loss 19592680
nsv522364 CNV Loss 19592680
nsv871813 CNV Loss 21882294

Variation tolerance for ZNF362 Gene

Residual Variation Intolerance Score: 25.65% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.14; 23.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF362 Gene

HapMap Linkage Disequilibrium report
ZNF362

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF362 Gene

Disorders for ZNF362 Gene

Relevant External Links for ZNF362

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF362
genes like me logo Genes that share disorders with ZNF362: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF362 Gene

Publications for ZNF362 Gene

  1. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks I.A. … Vertegaal A.C. (Nat. Struct. Mol. Biol. 2014) 67
  2. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 67
  3. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt K.T. … Blagoev B. (Sci. Signal. 2011) 67
  4. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PMID: 19690332) Mayya V. … Han D.K. (Sci. Signal. 2009) 67
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 67

Products for ZNF362 Gene

Sources for ZNF362 Gene

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