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Aliases for ZNF362 Gene

Aliases for ZNF362 Gene

  • Zinc Finger Protein 362 2 3 5
  • Rotund Homolog (Drosophila) 2
  • Rotund Homolog 3
  • Lin-29 3
  • RN 3

External Ids for ZNF362 Gene

Previous GeneCards Identifiers for ZNF362 Gene

  • GC00U991155
  • GC01P033494
  • GC01P033722
  • GC01P031852

Summaries for ZNF362 Gene

GeneCards Summary for ZNF362 Gene

ZNF362 (Zinc Finger Protein 362) is a Protein Coding gene. An important paralog of this gene is ZNF384.

UniProtKB/Swiss-Prot for ZNF362 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF362 Gene

Genomics for ZNF362 Gene

Regulatory Elements for ZNF362 Gene

Enhancers for ZNF362 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F033218 1.5 FANTOM5 Ensembl ENCODE 12.1 -35.7 -35667 3.7 PKNOX1 RAD21 RCOR1 FOS EGR2 SMARCA5 ZNF654 MCM3 ZHX2 CEBPB TRIM62 ZNF362 KIAA1522 GC01P033228
GH01F033295 0.9 ENCODE 11.2 +39.4 39368 1.2 HDGF ELF3 ZNF48 ZNF2 RAD21 ZNF143 ZNF207 CREM THAP11 SMARCA5 A3GALT2 ZNF362 MIR3605 PHC2 GC01P033299 GC01P033284
GH01F033298 0.8 ENCODE 11.6 +42.5 42528 0.2 CTCF KLF1 CBX3 KLF17 MAX ZNF2 RAD21 ZKSCAN1 ZNF316 GLIS2 ZNF362 MIR3605 PHC2 TSSK3 GC01P033299 GC01P033284
GH01F033222 0.2 ENCODE 12.1 -33.7 -33693 0.2 ZNF362 TRIM62 GC01P033228
GH01F033665 0.3 FANTOM5 1.2 +409.1 409124 0.1 ZNF362 PIR59446 LOC105378638
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF362 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF362 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000534222 193 2601 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF48 YY1 GLIS2 FOS ZNF263

Genomic Location for ZNF362 Gene

Chromosome:
1
Start:
33,256,307 bp from pter
End:
33,300,720 bp from pter
Size:
44,414 bases
Orientation:
Plus strand

Genomic View for ZNF362 Gene

Genes around ZNF362 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF362 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF362 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF362 Gene

Proteins for ZNF362 Gene

  • Protein details for ZNF362 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T0B9-ZN362_HUMAN
    Recommended name:
    Zinc finger protein 362
    Protein Accession:
    Q5T0B9
    Secondary Accessions:
    • Q8WYU4

    Protein attributes for ZNF362 Gene

    Size:
    420 amino acids
    Molecular mass:
    45814 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF362 Gene

Post-translational modifications for ZNF362 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF362 Gene

No data available for DME Specific Peptides for ZNF362 Gene

Domains & Families for ZNF362 Gene

Gene Families for ZNF362 Gene

Protein Domains for ZNF362 Gene

Suggested Antigen Peptide Sequences for ZNF362 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5T0B9

UniProtKB/Swiss-Prot:

ZN362_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 6 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 6 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF362: view

Function for ZNF362 Gene

Molecular function for ZNF362 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF362 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF362: view
genes like me logo Genes that share phenotypes with ZNF362: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF362 Gene

Localization for ZNF362 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF362 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF362 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF362 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF362: view

Pathways & Interactions for ZNF362 Gene

SuperPathways for ZNF362 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF362 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF362: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF362 Gene

Transcripts for ZNF362 Gene

Unigene Clusters for ZNF362 Gene

Zinc finger protein 362:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF362 Gene

No ASD Table

Relevant External Links for ZNF362 Gene

GeneLoc Exon Structure for
ZNF362
ECgene alternative splicing isoforms for
ZNF362

Expression for ZNF362 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF362 Gene

Protein differential expression in normal tissues from HIPED for ZNF362 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (25.5), Tlymphocyte (11.7), Placenta (8.5), Fetal testis (8.5), and Fetal Brain (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF362 Gene



Protein tissue co-expression partners for ZNF362 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF362 Gene:

ZNF362

SOURCE GeneReport for Unigene cluster for ZNF362 Gene:

Hs.743358
genes like me logo Genes that share expression patterns with ZNF362: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF362 Gene

Orthologs for ZNF362 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF362 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF362 34 35
  • 99.84 (n)
dog
(Canis familiaris)
Mammalia ZNF362 34 35
  • 95.19 (n)
cow
(Bos Taurus)
Mammalia ZNF362 34 35
  • 94.63 (n)
rat
(Rattus norvegicus)
Mammalia Zfp362 34
  • 92.82 (n)
mouse
(Mus musculus)
Mammalia Zfp362 34 16 35
  • 91.63 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF362 35
  • 76 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF362 34 35
  • 86.57 (n)
lizard
(Anolis carolinensis)
Reptilia ZNF362 35
  • 93 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf362 34
  • 80.81 (n)
zebrafish
(Danio rerio)
Actinopterygii znf362b 34 35
  • 73.32 (n)
znf362a 35
  • 70 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta sqz 35
  • 21 (a)
ManyToMany
rn 35
  • 16 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea lin-29 35
  • 23 (a)
OneToMany
Species where no ortholog for ZNF362 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZNF362 Gene

ENSEMBL:
Gene Tree for ZNF362 (if available)
TreeFam:
Gene Tree for ZNF362 (if available)

Paralogs for ZNF362 Gene

Variants for ZNF362 Gene

Sequence variations from dbSNP and Humsavar for ZNF362 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10595778 -- 33,296,841(+) TTTTT(-/TT)GGTAT intron-variant
rs10643513 -- 33,297,351(+) CTCTC(-/TAA)TGATA intron-variant
rs10671914 -- 33,295,611(+) AGAGA(-/AG/GA)AGCGC intron-variant
rs10753278 -- 33,274,005(+) CAGCC(A/G)TGGAG intron-variant
rs10753279 -- 33,290,312(+) tgcgg(C/T)gtttg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF362 Gene

Variant ID Type Subtype PubMed ID
nsv1112530 CNV deletion 24896259
nsv522364 CNV loss 19592680
nsv524709 CNV loss 19592680
nsv545963 CNV loss 21841781

Variation tolerance for ZNF362 Gene

Residual Variation Intolerance Score: 25.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.14; 23.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF362 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF362

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF362 Gene

Disorders for ZNF362 Gene

Relevant External Links for ZNF362

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF362

No disorders were found for ZNF362 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF362 Gene

Publications for ZNF362 Gene

  1. Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. (PMID: 25281560) Lambert J.P. … Gingras A.C. (J Proteomics 2015) 3 64
  2. SUMO-2 orchestrates chromatin modifiers in response to DNA damage. (PMID: 25772364) Hendriks I.A. … Vertegaal A.C. (Cell Rep. 2015) 4 64
  3. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4 64
  4. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks I.A. … Vertegaal A.C. (Nat. Struct. Mol. Biol. 2014) 4 64
  5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt K.T. … Blagoev B. (Sci. Signal. 2011) 4 64

Products for ZNF362 Gene

Sources for ZNF362 Gene

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