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Aliases for ZNF354B Gene

Aliases for ZNF354B Gene

  • Zinc Finger Protein 354B 2 3
  • KID2 3

External Ids for ZNF354B Gene

Summaries for ZNF354B Gene

GeneCards Summary for ZNF354B Gene

ZNF354B (Zinc Finger Protein 354B) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF529.

UniProtKB/Swiss-Prot for ZNF354B Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF354B Gene

Genomics for ZNF354B Gene

Genomic Location for ZNF354B Gene

178,859,953 bp from pter
178,888,122 bp from pter
28,170 bases
Plus strand

Genomic View for ZNF354B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF354B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF354B Gene

Regulatory Elements for ZNF354B Gene

Proteins for ZNF354B Gene

  • Protein details for ZNF354B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 354B
    Protein Accession:
    Secondary Accessions:
    • A8K0V2
    • Q5U5Z4

    Protein attributes for ZNF354B Gene

    612 amino acids
    Molecular mass:
    70529 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF354B Gene

Proteomics data for ZNF354B Gene at MOPED

Post-translational modifications for ZNF354B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF354B Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF354B Gene

Domains for ZNF354B Gene

Gene Families for ZNF354B Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF354B Gene


  • Contains 1 KRAB domain.:
    • Q96LW1
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q96LW1
  • Contains 13 C2H2-type zinc fingers.:
    • Q96LW1
genes like me logo Genes that share domains with ZNF354B: view

Function for ZNF354B Gene

Molecular function for ZNF354B Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF354B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003682 chromatin binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF354B: view

Phenotypes for ZNF354B Gene

GenomeRNAi human phenotypes for ZNF354B:
genes like me logo Genes that share phenotypes with ZNF354B: view

miRNA for ZNF354B Gene

miRTarBase miRNAs that target ZNF354B

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF354B Gene

Localization for ZNF354B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF354B Gene

Subcellular locations from

Jensen Localization Image for ZNF354B Gene COMPARTMENTS Subcellular localization image for ZNF354B gene
Compartment Confidence
nucleus 4
cytosol 2
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ZNF354B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF354B: view

Pathways for ZNF354B Gene

SuperPathways for ZNF354B Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF354B: view

Pathways by source for ZNF354B Gene

2 Reactome pathways for ZNF354B Gene

Interacting Proteins for ZNF354B Gene

Gene Ontology (GO) - Biological Process for ZNF354B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA --
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF354B: view

Transcripts for ZNF354B Gene

Unigene Clusters for ZNF354B Gene

Zinc finger protein 354B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF354B Gene

No ASD Table

Relevant External Links for ZNF354B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF354B Gene

mRNA expression in normal human tissues for ZNF354B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF354B Gene

SOURCE GeneReport for Unigene cluster for ZNF354B Gene Hs.724051

genes like me logo Genes that share expressions with ZNF354B: view

Orthologs for ZNF354B Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF354B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF354B 36
  • 99.62 (n)
  • 99.67 (a)
ZNF354B 37
  • 100 (a)
(Bos Taurus)
Mammalia LOC510078 36
  • 88.42 (n)
  • 87.05 (a)
ZNF354B 37
  • 87 (a)
(Canis familiaris)
Mammalia ZNF354B 36
  • 87.54 (n)
  • 89.34 (a)
ZNF354B 37
  • 79 (a)
(Mus musculus)
Mammalia Zfp354b 36
  • 81.91 (n)
  • 82.47 (a)
Zfp354b 16
Zfp354b 37
  • 83 (a)
(Monodelphis domestica)
Mammalia -- 37
  • 50 (a)
(Rattus norvegicus)
Mammalia LOC102556119 36
  • 83.31 (n)
  • 82.97 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8484 38
  • 27 (a)
CG3407 38
  • 41 (a)
Aef1 38
  • 57 (a)
Species with no ortholog for ZNF354B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF354B Gene

Gene Tree for ZNF354B (if available)
Gene Tree for ZNF354B (if available)

Paralogs for ZNF354B Gene

Selected SIMAP similar genes for ZNF354B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF354B: view

Variants for ZNF354B Gene

Sequence variations from dbSNP and Humsavar for ZNF354B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs1132331 -- 178,866,264(+) GAGGA(C/T)GTGGC reference, synonymous-codon
rs1132332 -- 178,866,276(+) GTGCT(C/G)TTTAC reference, synonymous-codon
rs1132333 -- 178,866,981(+) GGCTC(C/T)CATTT missense, reference
rs1132334 -- 178,867,001(+) AAAGT(A/C/G)ATCTC synonymous-codon, reference
rs3922928 -- 178,860,053(-) GTGAC(C/T)CGGCT utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF354B Gene

Variant ID Type Subtype PubMed ID
nsv883218 CNV Gain 21882294
nsv462574 CNV Loss 19166990
nsv823352 CNV Gain 20364138

Relevant External Links for ZNF354B Gene

HapMap Linkage Disequilibrium report

Disorders for ZNF354B Gene

(1) University of Copenhagen DISEASES for ZNF354B Gene

genes like me logo Genes that share disorders with ZNF354B: view

No data available for UniProtKB/Swiss-Prot for ZNF354B Gene

Publications for ZNF354B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF354B Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF354B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF354B
    • Block miRNA regulation of ZNF354B using miScript Target Protectors

    Sources for ZNF354B Gene

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