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Aliases for ZNF35 Gene

Aliases for ZNF35 Gene

  • Zinc Finger Protein 35 2 3
  • Zinc Finger Protein 35 (Clone HF.10) 2 3
  • Zinc Finger Protein HF.10 3 4
  • HF10 3 6
  • Zfp105 3
  • HF.10 3

External Ids for ZNF35 Gene

Previous GeneCards Identifiers for ZNF35 Gene

  • GC03P044155
  • GC03P043870
  • GC03P044509
  • GC03P044650
  • GC03P044665
  • GC03P044690

Summaries for ZNF35 Gene

GeneCards Summary for ZNF35 Gene

ZNF35 (Zinc Finger Protein 35) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is ZNF660.

UniProtKB/Swiss-Prot for ZNF35 Gene

  • May be involved in transcriptional regulation. Involved in cell differentiation and/or proliferation

Gene Wiki entry for ZNF35 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF35 Gene

Genomics for ZNF35 Gene

Regulatory Elements for ZNF35 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF35 Gene

Start:
44,648,616 bp from pter
End:
44,660,791 bp from pter
Size:
12,176 bases
Orientation:
Plus strand

Genomic View for ZNF35 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF35 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF35 Gene

Proteins for ZNF35 Gene

  • Protein details for ZNF35 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P13682-ZNF35_HUMAN
    Recommended name:
    Zinc finger protein 35
    Protein Accession:
    P13682
    Secondary Accessions:
    • B2RBU6
    • Q53Y54
    • Q96D01

    Protein attributes for ZNF35 Gene

    Size:
    527 amino acids
    Molecular mass:
    59089 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAA85451.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAG37343.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAA30268.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for ZNF35 Gene

Proteomics data for ZNF35 Gene at MOPED

Post-translational modifications for ZNF35 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF35 Gene

No data available for DME Specific Peptides for ZNF35 Gene

Domains for ZNF35 Gene

Gene Families for ZNF35 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF35 Gene

Suggested Antigen Peptide Sequences for ZNF35 Gene

Graphical View of Domain Structure for InterPro Entry

P13682

UniProtKB/Swiss-Prot:

ZNF35_HUMAN :
  • P13682
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF35: view

Function for ZNF35 Gene

Molecular function for ZNF35 Gene

GENATLAS Biochemistry: zinc finger protein 35,cHF.10 (C2H2 type,Kruppel-like),expressed in testis,involved in germ cell differentiation process
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation. Involved in cell differentiation and/or proliferation

Gene Ontology (GO) - Molecular Function for ZNF35 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding TAS 2108922
GO:0003700 sequence-specific DNA binding transcription factor activity IDA 1572646
GO:0043565 sequence-specific DNA binding IDA 8477855
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF35: view
genes like me logo Genes that share phenotypes with ZNF35: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF35 Gene

Localization for ZNF35 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF35 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF35 Gene COMPARTMENTS Subcellular localization image for ZNF35 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF35 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005623 cell ISS --
GO:0005634 nucleus IDA 20186958
GO:0048471 perinuclear region of cytoplasm IDA 20186958
genes like me logo Genes that share ontologies with ZNF35: view

Pathways for ZNF35 Gene

SuperPathways for ZNF35 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF35 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0007283 spermatogenesis ISS --
GO:0071300 cellular response to retinoic acid ISS 20186958
genes like me logo Genes that share ontologies with ZNF35: view

No data available for Pathways by source for ZNF35 Gene

Transcripts for ZNF35 Gene

Unigene Clusters for ZNF35 Gene

Zinc finger protein 35:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF35

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF35 Gene

No ASD Table

Relevant External Links for ZNF35 Gene

GeneLoc Exon Structure for
ZNF35
ECgene alternative splicing isoforms for
ZNF35

Expression for ZNF35 Gene

mRNA expression in normal human tissues for ZNF35 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF35 Gene

SOURCE GeneReport for Unigene cluster for ZNF35 Gene Hs.288658

genes like me logo Genes that share expressions with ZNF35: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF35 Gene

Orthologs for ZNF35 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF35 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF35 35
  • 99.68 (n)
  • 99.81 (a)
ZNF35 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF35 35
  • 86.78 (n)
  • 88.99 (a)
ZNF35 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF35 35
  • 90.64 (n)
  • 90.32 (a)
ZNF35 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp105 35
  • 84.48 (n)
  • 81.49 (a)
Zfp105 16
Zfp105 36
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp105 35
  • 85.56 (n)
  • 83.97 (a)
zebrafish
(Danio rerio)
Actinopterygii BX004879.1 36
  • 39 (a)
ManyToMany
BX005448.1 36
  • 39 (a)
ManyToMany
BX005448.2 36
  • 32 (a)
ManyToMany
BX890548.2 36
  • 39 (a)
ManyToMany
CABZ01008480.1 36
  • 38 (a)
ManyToMany
CR293532.1 36
  • 36 (a)
ManyToMany
CT573263.3 36
  • 38 (a)
ManyToMany
gb:am422109 36
  • 39 (a)
ManyToMany
si:ch211-226o13.2 36
  • 38 (a)
ManyToMany
si:ch211-283l16.1 36
  • 39 (a)
ManyToMany
si:dkey-16b10.2 36
  • 36 (a)
ManyToMany
si:dkey-22h13.2 36
  • 38 (a)
ManyToMany
si:dkey-237m9.1 36
  • 37 (a)
ManyToMany
si:dkey-54j5.2 36
  • 37 (a)
ManyToMany
si:dkey-56m15.3 36
  • 39 (a)
ManyToMany
zgc:173714 36
  • 36 (a)
ManyToMany
zgc:174694 36
  • 36 (a)
ManyToMany
zgc:174700 36
  • 39 (a)
ManyToMany
Species with no ortholog for ZNF35:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF35 Gene

ENSEMBL:
Gene Tree for ZNF35 (if available)
TreeFam:
Gene Tree for ZNF35 (if available)

Paralogs for ZNF35 Gene

Paralogs for ZNF35 Gene

Selected SIMAP similar genes for ZNF35 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZNF35 Gene

genes like me logo Genes that share paralogs with ZNF35: view

Variants for ZNF35 Gene

Sequence variations from dbSNP and Humsavar for ZNF35 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1402753 -- 44,660,246(-) CCAAA(C/T)AGCAT utr-variant-3-prime
rs1868603 -- 44,649,020(+) GCCTG(C/G)TCCGG intron-variant
rs2272044 -- 44,651,072(-) CTGCA(C/G)TCATC reference, missense, utr-variant-5-prime
rs3080644 -- 44,654,272(+) TGCCA(-/AC)ACTAT intron-variant
rs3732518 -- 44,658,889(-) CACTT(A/G)TCTGA reference, stop-gained

Relevant External Links for ZNF35 Gene

HapMap Linkage Disequilibrium report
ZNF35

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF35 Gene

Disorders for ZNF35 Gene

No disorders were found for ZNF35 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF35 Gene

Publications for ZNF35 Gene

  1. Structural and functional organization of the HF.10 human zinc finger gene (ZNF35) located on chromosome 3p21-p22. (PMID: 1572646) Lanfrancone L. … Lania L. (Genomics 1992) 2 3 4 23
  2. Localization of the human HF.10 finger gene on a chromosome region (3p21-22) frequently deleted in human cancers. (PMID: 2108922) Donti E. … Pelicci P.G. (Hum. Genet. 1990) 2 3
  3. Isolation of cDNAs encoding finger proteins and measurement of the corresponding mRNA levels during myeloid terminal differentiation. (PMID: 3380682) Pannuti A. … Lania L. (Nucleic Acids Res. 1988) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Expression of zinc finger protein 105 in the testis and its role in male fertility. (PMID: 20186958) Zhou H. … Lan Z.J. (Mol. Reprod. Dev. 2010) 3

Products for ZNF35 Gene

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