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Aliases for ZNF347 Gene

Aliases for ZNF347 Gene

  • Zinc Finger Protein 347 2 3 5
  • Zinc Finger Protein 1111 3 4
  • ZNF1111 3 4
  • Zinc Finger 1111 3
  • CTD-2620I22.7 3

External Ids for ZNF347 Gene

Previous GeneCards Identifiers for ZNF347 Gene

  • GC19M054273
  • GC19M054002
  • GC19M058085
  • GC19M058103
  • GC19M058261
  • GC19M058334
  • GC19M053642
  • GC19M049965
  • GC19M053627

Summaries for ZNF347 Gene

GeneCards Summary for ZNF347 Gene

ZNF347 (Zinc Finger Protein 347) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF160.

UniProtKB/Swiss-Prot for ZNF347 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF347 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF347 Gene

Genomics for ZNF347 Gene

Regulatory Elements for ZNF347 Gene

Enhancers for ZNF347 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H053977 1.3 Ensembl ENCODE 37.6 -816.0 -816024 5.8 HDGF PKNOX1 SIN3A FEZF1 ZNF2 ZNF766 ZNF143 SP3 NFYC REST PRPF31 ZNF525 LENG8-AS1 ZNF160 ZNF845 ZNF665 ZNF761 ZNF347 LENG8 ENSG00000235681
GH19H053881 1.4 Ensembl ENCODE dbSUPER 13.6 -718.5 -718504 2.9 RB1 KLF17 SIN3A GLI4 BMI1 ZBTB40 RAD21 ZEB1 GLIS2 EGR1 ZNF845 ENSG00000235681 ENSG00000269001 ZNF665 LENG8-AS1 LENG8 ZNF347 ZNF160 PRPF31 ZNF761
GH19H053553 1.2 ENCODE dbSUPER 13.7 -390.6 -390610 2.6 HDGF PKNOX1 ZNF133 SIN3A ZNF2 ETS1 ZNF302 ZNF143 FOS ATF7 ZNF160 ZNF845 PRPF31 ENSG00000269001 ZNF347 ZNF600 LENG8-AS1 LENG8 ENSG00000269288 ZNF701
GH19H053961 1.2 FANTOM5 ENCODE 13.4 -798.2 -798177 0.3 PKNOX1 NFRKB GLI4 ZBTB40 GLIS2 ZNF366 EGR2 YY2 ZBTB11 ZNF398 ZNF347 ZNF702P ENSG00000267838 ZNF665 CACNG8 TFPT NDUFA3 CACNG7 MYADM PRPF31
GH19H053517 1.1 ENCODE 14.4 -355.7 -355677 4.8 PKNOX1 ARNT ARID4B SIN3A YY1 ZNF766 ZNF143 SP3 ZHX2 MXD4 ZNF137P LENG8-AS1 PRPF31 ZNF160 ZNF761 ZNF525 ZNF611 LENG8 ZNF665 ZNF677
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF347 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF347 Gene

Genomic Locations for ZNF347 Gene
39,867 bases
Minus strand

Genomic View for ZNF347 Gene

Genes around ZNF347 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF347 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF347 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF347 Gene

Proteins for ZNF347 Gene

  • Protein details for ZNF347 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 347
    Protein Accession:
    Secondary Accessions:
    • B3KU77
    • B9EG59
    • G5E9N4
    • Q8TCN1

    Protein attributes for ZNF347 Gene

    839 amino acids
    Molecular mass:
    95770 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ZNF347 Gene

    Alternative splice isoforms for ZNF347 Gene


neXtProt entry for ZNF347 Gene

Post-translational modifications for ZNF347 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF347 Gene

Domains & Families for ZNF347 Gene

Gene Families for ZNF347 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF347 Gene

Suggested Antigen Peptide Sequences for ZNF347 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF347: view

Function for ZNF347 Gene

Molecular function for ZNF347 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF347 Gene

Gene Ontology (GO) - Molecular Function for ZNF347 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF347: view
genes like me logo Genes that share phenotypes with ZNF347: view

miRNA for ZNF347 Gene

miRTarBase miRNAs that target ZNF347

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF347 Gene

Localization for ZNF347 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF347 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF347 gene
Compartment Confidence
nucleus 5
cytoskeleton 3
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF347 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF347: view

Pathways & Interactions for ZNF347 Gene

SuperPathways for ZNF347 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF347: view

Pathways by source for ZNF347 Gene

2 Reactome pathways for ZNF347 Gene

Gene Ontology (GO) - Biological Process for ZNF347 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF347: view

No data available for SIGNOR curated interactions for ZNF347 Gene

Drugs & Compounds for ZNF347 Gene

No Compound Related Data Available

Transcripts for ZNF347 Gene

Unigene Clusters for ZNF347 Gene

Zinc finger protein 347:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF347 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d · 4e ^ 5a · 5b ^ 6a · 6b · 6c
SP1: - - -
SP2: - -
SP3: - - -
SP4: - -
SP5: - -

Relevant External Links for ZNF347 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF347 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF347 Gene

Protein differential expression in normal tissues from HIPED for ZNF347 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF347 Gene

Protein tissue co-expression partners for ZNF347 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF347 Gene:


SOURCE GeneReport for Unigene cluster for ZNF347 Gene:


Evidence on tissue expression from TISSUES for ZNF347 Gene

  • Nervous system(4.3)
genes like me logo Genes that share expression patterns with ZNF347: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF347 Gene

Orthologs for ZNF347 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF347 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF347 33
  • 99.4 (n)
-- 34
  • 53 (a)
(Bos Taurus)
Mammalia -- 34
  • 50 (a)
-- 34
  • 50 (a)
-- 34
  • 49 (a)
-- 34
  • 49 (a)
-- 34
  • 44 (a)
(Mus musculus)
Mammalia Zfp51 34
  • 41 (a)
fruit fly
(Drosophila melanogaster)
Insecta crol 35
  • 40 (a)
CG8484 35
  • 27 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 43 (a)
-- 34
  • 39 (a)
-- 34
  • 38 (a)
-- 34
  • 36 (a)
CSA.1668 34
  • 35 (a)
-- 34
  • 33 (a)
Species where no ortholog for ZNF347 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF347 Gene

Gene Tree for ZNF347 (if available)
Gene Tree for ZNF347 (if available)

Paralogs for ZNF347 Gene

(517) SIMAP similar genes for ZNF347 Gene using alignment to 5 proteins: Pseudogenes for ZNF347 Gene

genes like me logo Genes that share paralogs with ZNF347: view

Variants for ZNF347 Gene

Sequence variations from dbSNP and Humsavar for ZNF347 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000179911 -- 53,146,830(+) ATAGA(A/C)AACCT intron-variant
rs1000197385 -- 53,159,141(+) GCTGG(A/G)GCGGA upstream-variant-2KB
rs1000370832 -- 53,140,732(+) TCTGA(C/T)GCCTT reference, missense
rs1000440290 -- 53,154,593(+) GGGAG(A/G)CAACA intron-variant
rs1000544979 -- 53,156,406(+) AAAAA(A/G)AAAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF347 Gene

Variant ID Type Subtype PubMed ID
nsv960866 CNV duplication 23825009
nsv478009 CNV novel sequence insertion 20440878
nsv472019 CNV novel sequence insertion 20440878
nsv428370 CNV loss 18775914
nsv1141887 OTHER inversion 24896259
nsv1078889 OTHER inversion 25765185
esv3644741 CNV gain 21293372
esv3644740 CNV gain 21293372
esv2758769 CNV loss 17122850
esv2718787 CNV deletion 23290073

Variation tolerance for ZNF347 Gene

Residual Variation Intolerance Score: 24% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.45; 28.43% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF347 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF347 Gene

Disorders for ZNF347 Gene

Relevant External Links for ZNF347

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF347 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF347 Gene

Publications for ZNF347 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 60
  3. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 60
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 60

Products for ZNF347 Gene

Sources for ZNF347 Gene

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