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Aliases for ZNF345 Gene

Aliases for ZNF345 Gene

  • Zinc Finger Protein 345 2 3
  • Zinc Finger Protein HZF10 3 4
  • HZF10 3

External Ids for ZNF345 Gene

Previous GeneCards Identifiers for ZNF345 Gene

  • GC19P038019
  • GC19P037801
  • GC19P042017
  • GC19P042033
  • GC19P037341
  • GC19P033809

Summaries for ZNF345 Gene

GeneCards Summary for ZNF345 Gene

ZNF345 (Zinc Finger Protein 345) is a Protein Coding gene. An important paralog of this gene is ZNF630.

UniProtKB/Swiss-Prot for ZNF345 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF345 Gene

Genomics for ZNF345 Gene

Genomic Location for ZNF345 Gene

36,850,358 bp from pter
36,913,029 bp from pter
62,672 bases
Plus strand

Genomic View for ZNF345 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF345 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF345 Gene

No data available for Regulatory Elements for ZNF345 Gene

Proteins for ZNF345 Gene

  • Protein details for ZNF345 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 345
    Protein Accession:
    Secondary Accessions:

    Protein attributes for ZNF345 Gene

    488 amino acids
    Molecular mass:
    55383 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF345 Gene

Proteomics data for ZNF345 Gene at MOPED

Post-translational modifications for ZNF345 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF345 Gene

Domains for ZNF345 Gene

Gene Families for ZNF345 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF345 Gene

Suggested Antigen Peptide Sequences for ZNF345 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q14585
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF345: view

Function for ZNF345 Gene

Molecular function for ZNF345 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF345 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF345: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF345 Gene

Localization for ZNF345 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF345 Gene

Subcellular locations from

Jensen Localization Image for ZNF345 Gene COMPARTMENTS Subcellular localization image for ZNF345 gene
Compartment Confidence
nucleus 5
cytosol 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for ZNF345 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF345: view

Pathways for ZNF345 Gene

SuperPathways for ZNF345 Gene

No Data Available

Interacting Proteins for ZNF345 Gene

Gene Ontology (GO) - Biological Process for ZNF345 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter TAS 9278146
GO:0006355 regulation of transcription, DNA-templated IBA --
GO:0006359 regulation of transcription from RNA polymerase III promoter TAS 9278146
GO:0006366 transcription from RNA polymerase II promoter TAS 9278146
GO:0006383 transcription from RNA polymerase III promoter TAS 9278146
genes like me logo Genes that share ontologies with ZNF345: view

No data available for Pathways by source for ZNF345 Gene

Transcripts for ZNF345 Gene

Unigene Clusters for ZNF345 Gene

Zinc finger protein 345:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF345

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF345 Gene

No ASD Table

Relevant External Links for ZNF345 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF345 Gene

mRNA expression in normal human tissues for ZNF345 Gene

SOURCE GeneReport for Unigene cluster for ZNF345 Gene Hs.362324

genes like me logo Genes that share expressions with ZNF345: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for ZNF345 Gene

Orthologs for ZNF345 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF345 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF345 35
  • 92.73 (n)
  • 91.56 (a)
ZNF383 36
  • 43 (a)
(Canis familiaris)
Mammalia ZNF571 35
  • 89.88 (n)
  • 89.49 (a)
(Pan troglodytes)
Mammalia ZNF345 35
  • 99.73 (n)
  • 99.39 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 40 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7987 37
  • 33 (a)
Species with no ortholog for ZNF345:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF345 Gene

Gene Tree for ZNF345 (if available)
Gene Tree for ZNF345 (if available)

Paralogs for ZNF345 Gene

Selected SIMAP similar genes for ZNF345 Gene using alignment to 7 proteins: Pseudogenes for ZNF345 Gene

genes like me logo Genes that share paralogs with ZNF345: view

Variants for ZNF345 Gene

Sequence variations from dbSNP and Humsavar for ZNF345 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs475196 -- 36,873,653(+) gacag(C/T)ccctg intron-variant
rs477725 -- 36,883,364(+) tgaag(C/T)tttct intron-variant
rs477942 -- 36,855,486(+) tttcg(A/C)tcttg intron-variant
rs478272 -- 36,879,906(+) TTCAT(C/T)TTTAT intron-variant, downstream-variant-500B
rs486466 -- 36,856,082(+) CACTT(A/G)ATACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF345 Gene

Variant ID Type Subtype PubMed ID
nsv817833 CNV Loss 17921354
nsv521605 CNV Loss 19592680
nsv911651 CNV Loss 21882294
nsv458569 CNV Loss 19166990
nsv523848 CNV Loss 19592680
nsv819209 CNV Loss 19587683
nsv524754 CNV Loss 19592680

Relevant External Links for ZNF345 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF345 Gene

Disorders for ZNF345 Gene

No disorders were found for ZNF345 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZNF345 Gene

Publications for ZNF345 Gene

  1. Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937. (PMID: 7865130) Abrink M. … Hellman L. (DNA Cell Biol. 1995) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Silencing of RNA polymerases II and III-dependent transcription by the KRAB protein domain of KOX1, a KrA1ppel-type zinc finger factor. (PMID: 9278146) Moosmann P. … Schaffner W. (Biol. Chem. 1997) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF345 Gene

Sources for ZNF345 Gene

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