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Aliases for ZNF343 Gene

Aliases for ZNF343 Gene

  • Zinc Finger Protein 343 2 3
  • DJ734P14.5 3

External Ids for ZNF343 Gene

Previous GeneCards Identifiers for ZNF343 Gene

  • GC00U991036
  • GC20M002411
  • GC20M002412
  • GC20M002413
  • GC20M002414
  • GC20M002415
  • GC20M002416
  • GC20M002417
  • GC20M002418
  • GC20M002419
  • GC20M002420
  • GC20M002447
  • GC20M002462

Summaries for ZNF343 Gene

GeneCards Summary for ZNF343 Gene

ZNF343 (Zinc Finger Protein 343) is a Protein Coding gene. Diseases associated with ZNF343 include ocular hypertension. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF169.

UniProtKB/Swiss-Prot for ZNF343 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF343 Gene

Genomics for ZNF343 Gene

Regulatory Elements for ZNF343 Gene

Transcription factor binding sites by QIAGEN in the ZNF343 gene promoter:

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF343 Gene

2,481,817 bp from pter
2,524,702 bp from pter
42,886 bases
Minus strand

Genomic View for ZNF343 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF343 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF343 Gene

Proteins for ZNF343 Gene

  • Protein details for ZNF343 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 343
    Protein Accession:
    Secondary Accessions:
    • Q5JXU8
    • Q5JXU9
    • Q8N8F2
    • Q96EX8
    • Q96NA5
    • Q9BQB0

    Protein attributes for ZNF343 Gene

    599 amino acids
    Molecular mass:
    69220 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF343 Gene


neXtProt entry for ZNF343 Gene

Proteomics data for ZNF343 Gene at MOPED

Post-translational modifications for ZNF343 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF343 Gene

Domains for ZNF343 Gene

Gene Families for ZNF343 Gene

Protein Domains for ZNF343 Gene

Suggested Antigen Peptide Sequences for ZNF343 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF343: view

Function for ZNF343 Gene

Molecular function for ZNF343 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF343 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF343: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF343 Gene

Localization for ZNF343 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF343 Gene

Subcellular locations from

Jensen Localization Image for ZNF343 Gene COMPARTMENTS Subcellular localization image for ZNF343 gene
Compartment Confidence
nucleus 3
cytosol 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ZNF343 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF343: view

Pathways for ZNF343 Gene

SuperPathways for ZNF343 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF343: view

Pathways by source for ZNF343 Gene

2 Reactome pathways for ZNF343 Gene

Gene Ontology (GO) - Biological Process for ZNF343 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF343: view

Transcripts for ZNF343 Gene

Unigene Clusters for ZNF343 Gene

Zinc finger protein 343:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF343

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF343 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b
SP1: - - - - - - -
SP2: - - - - -
SP3: - -
SP4: -

Relevant External Links for ZNF343 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF343 Gene

mRNA expression in normal human tissues for ZNF343 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF343 Gene

SOURCE GeneReport for Unigene cluster for ZNF343 Gene Hs.516846

genes like me logo Genes that share expressions with ZNF343: view

Expression partners for ZNF343 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF343 Gene

Orthologs for ZNF343 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF343 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF343 35
  • 99.61 (n)
  • 99 (a)
ZNF343 36
  • 99 (a)
Species with no ortholog for ZNF343:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF343 Gene

Gene Tree for ZNF343 (if available)
Gene Tree for ZNF343 (if available)

Paralogs for ZNF343 Gene

Paralogs for ZNF343 Gene

(461) SIMAP similar genes for ZNF343 Gene using alignment to 1 proteins: Pseudogenes for ZNF343 Gene

genes like me logo Genes that share paralogs with ZNF343: view

Variants for ZNF343 Gene

Sequence variations from dbSNP and Humsavar for ZNF343 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs724187 -- 2,517,325(+) CAAAT(A/C)TACAC intron-variant
rs1001447 -- 2,524,587(-) GTCTC(G/T)GTCCT upstream-variant-2KB
rs1127478 -- 2,523,469(-) TGTAC(A/C)CGaaa intron-variant
rs1543385 -- 2,482,259(-) ACCCC(C/G)CAGTA downstream-variant-500B
rs1547061 -- 2,498,384(+) GTGCT(A/G)AAGAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF343 Gene

Variant ID Type Subtype PubMed ID
nsv470535 CNV Gain 18288195
dgv1303e1 CNV Complex 17122850
nsv912601 CNV Loss 21882294
nsv3260 CNV Insertion 18451855

Relevant External Links for ZNF343 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF343 Gene

Disorders for ZNF343 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for ZNF343 Gene in MalaCards »

(1) Disease for ZNF343 Gene

(1) University of Copenhagen DISEASES for ZNF343 Gene

Relevant External Links for ZNF343

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with ZNF343: view

No data available for OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for ZNF343 Gene

Publications for ZNF343 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF343 Gene

Sources for ZNF343 Gene

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