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Aliases for ZNF343 Gene

Aliases for ZNF343 Gene

  • Zinc Finger Protein 343 2 3 5
  • DJ734P14.5 3

External Ids for ZNF343 Gene

Previous GeneCards Identifiers for ZNF343 Gene

  • GC00U991036
  • GC20M002411
  • GC20M002412
  • GC20M002413
  • GC20M002414
  • GC20M002415
  • GC20M002416
  • GC20M002417
  • GC20M002418
  • GC20M002419
  • GC20M002420
  • GC20M002447
  • GC20M002462

Summaries for ZNF343 Gene

GeneCards Summary for ZNF343 Gene

ZNF343 (Zinc Finger Protein 343) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF169.

UniProtKB/Swiss-Prot for ZNF343 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF343 Gene

Genomics for ZNF343 Gene

Regulatory Elements for ZNF343 Gene

Enhancers for ZNF343 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF343 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF343 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF343 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF343 gene promoter:

Genomic Location for ZNF343 Gene

2,480,071 bp from pter
2,524,702 bp from pter
44,632 bases
Minus strand

Genomic View for ZNF343 Gene

Genes around ZNF343 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF343 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF343 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF343 Gene

Proteins for ZNF343 Gene

  • Protein details for ZNF343 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 343
    Protein Accession:
    Secondary Accessions:
    • Q5JXU8
    • Q5JXU9
    • Q8N8F2
    • Q96EX8
    • Q96NA5
    • Q9BQB0

    Protein attributes for ZNF343 Gene

    599 amino acids
    Molecular mass:
    69220 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF343 Gene


neXtProt entry for ZNF343 Gene

Proteomics data for ZNF343 Gene at MOPED

Post-translational modifications for ZNF343 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF343 Gene

Domains & Families for ZNF343 Gene

Gene Families for ZNF343 Gene

Protein Domains for ZNF343 Gene

Suggested Antigen Peptide Sequences for ZNF343 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF343: view

Function for ZNF343 Gene

Molecular function for ZNF343 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF343 Gene

GenomeRNAi human phenotypes for ZNF343:
genes like me logo Genes that share phenotypes with ZNF343: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF343 Gene

Localization for ZNF343 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF343 Gene

Subcellular locations from

Jensen Localization Image for ZNF343 Gene COMPARTMENTS Subcellular localization image for ZNF343 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF343 Gene

Pathways & Interactions for ZNF343 Gene

SuperPathways for ZNF343 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF343: view

Pathways by source for ZNF343 Gene

2 Reactome pathways for ZNF343 Gene

Gene Ontology (GO) - Biological Process for ZNF343 Gene


No data available for SIGNOR curated interactions for ZNF343 Gene

Drugs & Compounds for ZNF343 Gene

No Compound Related Data Available

Transcripts for ZNF343 Gene

Unigene Clusters for ZNF343 Gene

Zinc finger protein 343:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF343 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b
SP1: - - - - - - -
SP2: - - - - -
SP3: - -
SP4: -

Relevant External Links for ZNF343 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF343 Gene

mRNA expression in normal human tissues for ZNF343 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF343 Gene

SOURCE GeneReport for Unigene cluster for ZNF343 Gene Hs.516846

genes like me logo Genes that share expression patterns with ZNF343: view

Protein tissue co-expression partners for ZNF343 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF343 Gene

Orthologs for ZNF343 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF343 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF343 35
  • 99.61 (n)
  • 99 (a)
ZNF343 36
  • 99 (a)
Species with no ortholog for ZNF343:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF343 Gene

Gene Tree for ZNF343 (if available)
Gene Tree for ZNF343 (if available)

Paralogs for ZNF343 Gene

Paralogs for ZNF343 Gene

(461) SIMAP similar genes for ZNF343 Gene using alignment to 1 proteins: Pseudogenes for ZNF343 Gene

genes like me logo Genes that share paralogs with ZNF343: view

Variants for ZNF343 Gene

Sequence variations from dbSNP and Humsavar for ZNF343 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs6049415 - 2,483,402(+) TATAA(A/G)GCTTC reference, missense
rs1001447 -- 2,524,587(-) GTCTC(G/T)GTCCT upstream-variant-2KB
rs724187 -- 2,517,325(+) CAAAT(A/C)TACAC intron-variant
rs1543385 -- 2,482,259(-) ACCCC(C/G)CAGTA utr-variant-3-prime
rs1547061 -- 2,498,384(+) GTGCT(A/G)AAGAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF343 Gene

Variant ID Type Subtype PubMed ID
nsv470535 CNV Gain 18288195
dgv1303e1 CNV Complex 17122850
nsv912601 CNV Loss 21882294
nsv3260 CNV Insertion 18451855

Variation tolerance for ZNF343 Gene

Residual Variation Intolerance Score: 85.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.17; 61.69% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF343 Gene

Disorders for ZNF343 Gene

Relevant External Links for ZNF343

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF343 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF343 Gene

Publications for ZNF343 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  4. Genetic loci for blood lipid levels identified by linkage and association analyses in Caribbean Hispanics. (PMID: 21558551) Dong C. … Sacco R.L. (J. Lipid Res. 2011) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for ZNF343 Gene

Sources for ZNF343 Gene