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Aliases for ZNF343 Gene

Aliases for ZNF343 Gene

  • Zinc Finger Protein 343 2 3
  • DJ734P14.5 3

External Ids for ZNF343 Gene

Summaries for ZNF343 Gene

GeneCards Summary for ZNF343 Gene

ZNF343 (Zinc Finger Protein 343) is a Protein Coding gene. Diseases associated with ZNF343 include ocular hypertension. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF169.

UniProtKB/Swiss-Prot for ZNF343 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF343 Gene

Genomics for ZNF343 Gene

Genomic Location for ZNF343 Gene

Start:
2,481,817 bp from pter
End:
2,524,702 bp from pter
Size:
42,886 bases
Orientation:
Minus strand

Genomic View for ZNF343 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF343 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF343 Gene

Regulatory Elements for ZNF343 Gene

Transcription factor binding sites by QIAGEN in the ZNF343 gene promoter:

Proteins for ZNF343 Gene

  • Protein details for ZNF343 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P1L6-ZN343_HUMAN
    Recommended name:
    Zinc finger protein 343
    Protein Accession:
    Q6P1L6
    Secondary Accessions:
    • Q5JXU8
    • Q5JXU9
    • Q8N8F2
    • Q96EX8
    • Q96NA5
    • Q9BQB0

    Protein attributes for ZNF343 Gene

    Size:
    599 amino acids
    Molecular mass:
    69220 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF343 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF343 Gene

Proteomics data for ZNF343 Gene at MOPED

Post-translational modifications for ZNF343 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZNF343 Gene

Domains for ZNF343 Gene

Gene Families for ZNF343 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF343 Gene

UniProtKB/Swiss-Prot:

ZN343_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q6P1L6
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q6P1L6
Similarity:
  • Contains 12 C2H2-type zinc fingers.:
    • Q6P1L6
genes like me logo Genes that share domains with ZNF343: view

Function for ZNF343 Gene

Molecular function for ZNF343 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF343 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF343: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF343 Gene

Localization for ZNF343 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF343 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF343 Gene COMPARTMENTS Subcellular localization image for ZNF343 gene
Compartment Confidence
nucleus 3
cytosol 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ZNF343 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF343: view

Pathways for ZNF343 Gene

SuperPathways for ZNF343 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF343: view

Pathways by source for ZNF343 Gene

2 Reactome pathways for ZNF343 Gene

Gene Ontology (GO) - Biological Process for ZNF343 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF343: view

Transcripts for ZNF343 Gene

Unigene Clusters for ZNF343 Gene

Zinc finger protein 343:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF343 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b
SP1: - - - - - - -
SP2: - - - - -
SP3: - -
SP4: -
SP5:

Relevant External Links for ZNF343 Gene

GeneLoc Exon Structure for
ZNF343
ECgene alternative splicing isoforms for
ZNF343

Expression for ZNF343 Gene

mRNA expression in normal human tissues for ZNF343 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF343 Gene

SOURCE GeneReport for Unigene cluster for ZNF343 Gene Hs.516846

genes like me logo Genes that share expressions with ZNF343: view

Orthologs for ZNF343 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF343 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF343 36
  • 99.61 (n)
  • 99 (a)
ZNF343 37
  • 99 (a)
OneToOne
Species with no ortholog for ZNF343:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF343 Gene

ENSEMBL:
Gene Tree for ZNF343 (if available)
TreeFam:
Gene Tree for ZNF343 (if available)

Paralogs for ZNF343 Gene

Paralogs for ZNF343 Gene

Selected SIMAP similar genes for ZNF343 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF343 Gene

genes like me logo Genes that share paralogs with ZNF343: view

Variants for ZNF343 Gene

Sequence variations from dbSNP and Humsavar for ZNF343 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs724187 -- 2,517,325(+) CAAAT(A/C)TACAC intron-variant
rs1001447 -- 2,524,587(-) GTCTC(G/T)GTCCT upstream-variant-2KB
rs1127478 -- 2,523,469(-) TGTAC(A/C)CGaaa intron-variant
rs1543385 -- 2,482,259(-) ACCCC(C/G)CAGTA downstream-variant-500B
rs1547061 -- 2,498,384(+) GTGCT(A/G)AAGAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF343 Gene

Variant ID Type Subtype PubMed ID
nsv470535 CNV Gain 18288195
dgv1303e1 CNV Complex 17122850
nsv912601 CNV Loss 21882294
nsv3260 CNV Insertion 18451855

Relevant External Links for ZNF343 Gene

HapMap Linkage Disequilibrium report
ZNF343

Disorders for ZNF343 Gene

(1) MalaCards Diseases for ZNF343 Gene

Search for ZNF343 Gene in MalaCards »

(1) University of Copenhagen DISEASES for ZNF343 Gene

Relevant External Links for ZNF343

Genetic Association Database (GAD)
ZNF343
genes like me logo Genes that share disorders with ZNF343: view

No data available for UniProtKB/Swiss-Prot for ZNF343 Gene

Publications for ZNF343 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF343 Gene

Sources for ZNF343 Gene

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