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ZNF33B Gene

protein-coding   GIFtS: 51
GCID: GC10M043084

Zinc Finger Protein 33B

(Previous names: zinc finger protein 33b (KOX 31), zinc finger protein 11B)
(Previous symbol: ZNF11B)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 33B1 2     Zinc Finger Protein 11B1 3
ZNF11B1 2 3 5     Zinc Finger Protein KOX22 3
KOX22 3 5     KOX312
Zinc Finger Protein 33b (KOX 31)1 2     Zinc Finger Protein 11b (KOX 2)2

External Ids:    HGNC: 130971   Entrez Gene: 75822   Ensembl: ENSG000001966937   OMIM: 1945225   UniProtKB: Q067323   

Export aliases for ZNF33B gene to outside databases

Previous GC identifers: GC10M042377 GC10U900001 GC10P038188 GC07P006406 GC03P044571 GC10M042405 GC10M043069 GC10M039611


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZNF33B Gene:
ZNF33B (zinc finger protein 33B) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF334.

UniProtKB/Swiss-Prot: ZN33B_HUMAN, Q06732
Function: May be involved in transcriptional regulation

Gene Wiki entry for ZNF33B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for ZNF33B
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ZNF33B promoter sequence
   Search Chromatin IP Primers for ZNF33B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF33B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q11.2   Ensembl cytogenetic band:  10q11.21   HGNC cytogenetic band: 10q11.2

ZNF33B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF33B gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M043084:  view genomic region     (about GC identifiers)

Start:
43,084,555 bp from pter      End:
43,133,992 bp from pter
Size:
49,438 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZN33B_HUMAN, Q06732 (See protein sequence)
Recommended Name: Zinc finger protein 33B  
Size: 778 amino acids; 90683 Da
Sequence caution: Sequence=AAH48313.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
Secondary accessions: Q06731 Q32MA2 Q86XY8 Q8NDW3

Explore the universe of human proteins at neXtProt for ZNF33B: NX_Q06732

Explore proteomics data for ZNF33B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF33B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_008886.1  
    ENSEMBL proteins: 
     ENSP00000352444  
    Reactome Protein details: Q06732

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    4 InterPro protein domains:
     IPR001909 Krueppel-associated_box
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q06732

    ProtoNet protein and cluster: Q06732

    2 Blocks protein domains:
    IPB001909 KRAB box
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZN33B_HUMAN, Q06732
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 16 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain


    Find genes that share domains with ZNF33B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN33B_HUMAN, Q06732
    Function: May be involved in transcriptional regulation

         Genatlas biochemistry entry for ZNF33B:
    zinc finger protein 33b (KOX31) (C2H2 type,Kruppel-like)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IBA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZNF33B           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for ZNF33B:
     Increased S DNA content  S arrest 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZNF33B
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    hsa-miR-181c hsa-miR-578 hsa-miR-181a hsa-miR-181d hsa-miR-374c hsa-miR-655 hsa-miR-302f hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidZNF33B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZNF33B

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN33B_HUMAN, Q06732: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    Find genes that share ontologies with ZNF33B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZNF33B About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40


    Find genes that share SuperPaths with ZNF33B           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZNF33B
        Generic Transcription Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF33B
    Interactions:

        Search GeneGlobe Interaction Network for ZNF33B

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for ZNF33B (Q067322, 3 ENSP000003524444) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HAP1P542572, 3, ENSP000003340024MINT-64056 MINT-3979808 I2D: score=3 STRING: ENSP00000334002
    ZHX1Q9UKY12, 3, ENSP000002978574MINT-3979791 I2D: score=2 STRING: ENSP00000297857
    HTTP428583, ENSP000003471844I2D: score=1 STRING: ENSP00000347184
    CBX6ENSP000003844904STRING: ENSP00000384490
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IBA--

    Find genes that share ontologies with ZNF33B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF33B (ZN33B)

    1 HMDB Compound for ZNF33B    About this table
    CompoundSynonyms CAS #PubMed Ids
    ZincZinc (see all 2)7440-66-6--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZNF33B gene: 
    NM_006955.1  

    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000359467(uc001jaf.1 uc001jag.1)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ZNF33B (see all 13):
    hsa-miR-181c hsa-miR-578 hsa-miR-181a hsa-miR-181d hsa-miR-374c hsa-miR-655 hsa-miR-302f hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidZNF33B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZNF33B
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    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ZNF33B
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF33B
      QuantiFast Probe-based Assays in human, mouse, rat ZNF33B

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZNF33B (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d
    SP1:                          -                       -     -                           
    SP2:                          -                       -     -                           
    SP3:                          -                                                         
    SP4:                          -                       -     -                           
    SP5:                          -                 -     -     -                           


    ECgene alternative splicing isoforms for ZNF33B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF33B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZNF33B Expression
    About this image

    ZNF33B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF33B Protein Expression
        Custom PCR Arrays for ZNF33B
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZNF33B gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    37(a)
    1 → many
    2(350396-358052)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    37(a)
    many ↔ many
    GL343434.1(730965-746895)
    zebrafish
    (Danio rerio)
    Actinopterygii BX004873.26
    Uncharacterized protein
    45(a)
    many ↔ many
    Zv9_scaffold3517(90712-167294) ENSDARG00000089173
            Species with no ortholog for ZNF33B

    ENSEMBL Gene Tree for ZNF33B (if available)
    TreeFam Gene Tree for ZNF33B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF33B gene
    ZNF3342  ZNF4202  ZNF780A2  ZNF6652  ZNF72  ZNF232  ZNF33A2  RBAK2  
    ZNF7172  ZNF302  ZNF5732  ZNF5402  ZNF2512  ZNF6052  ZNF842  ZNF1892  
    ZNF5712  ZNF6302  ZNF3372  ZNF2832  ZNF4042  ZNF1352  ZNF4842  ZNF122  
    ZNF3452  ZNF1842  ZNF6992  ZNF412  ZNF6152  ZNF4702  ZNF5692  
    Selected SIMAP similar genes for ZNF33B using alignment to 3 protein entries:     ZN33B_HUMAN (see all proteins) (see all similar genes):
    ZNF33A    POM121C    ZNF577    ZNF844    ZNF83    ZNF320
    ZNF707    FIK    ZNF250    ZNF789    ZNF124    DKFZp686H10254
    RBAK-RBAKDN    ZNF529    ZNF705B    ZSCAN21    ZFP90    ZFP57

    Find genes that share paralogs with ZNF33B           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ZNF33B
    PGOHUM00000233110


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZNF33B (see all 1292)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1485381941,2
    C--43084055(+) ACCAAC/TTCTCA 1 -- ds50010--------
    rs1912757281,2
    --43084071(+) GTGAGA/GAGGAC 1 -- ds50010--------
    rs1830387871,2
    --43084087(+) ATGCCA/GGGCAG 1 -- ds50010--------
    rs1884671891,2
    --43084256(+) TTAGGA/CATAAG 1 -- ds50010--------
    rs1428560071,2
    --43084379(+) TCAGAC/TGTCAA 1 -- ds50010--------
    rs1506350591,2
    C--43084387(+) CAAGAA/GAACCA 1 -- ds50010--------
    rs1174919811,2
    F--43084623(+) GTTACA/CGAAAA 1 -- ut311Minor allele frequency- C:0.02NA 120
    rs109002531,2
    C,F,A,H--43084726(+) GTTCAT/CTTGTT 1 -- ut3111Minor allele frequency- C:0.25NS EA WA CSA NA 744
    rs97876821,2
    C,F--43084736(+) tacaaT/Ctgatg 1 -- ut313Minor allele frequency- C:0.05WA NA EA 358
    rs1416969191,2
    C--43084802(+) CTCTG-/TGTTTT
    CCGTTCAC
    TGTTT
    1 -- ut310--------

    HapMap Linkage Disequilibrium report for ZNF33B (43084555 - 43133992 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ZNF33B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2669368CNV Deletion23128226
    esv34929CNV Loss17911159
    nsv895064CNV Gain21882294
    nsv469725CNV Gain16826518
    essv7677CNV CNV17122850
    dgv248e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 194522    OMIM disorders: --


    Find genes that share disorders with ZNF33B           About GenesLikeMe

    Genetic Association Database (GAD): ZNF33B
    Human Genome Epidemiology (HuGE) Navigator: ZNF33B (1 document)

    Export disorders for ZNF33B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF33B gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with ZNF33B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution. (PubMed id 8464732)1, 2, 9 Tunnacliffe A.... Ponder B.A. (Nucleic Acids Res. 1993)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    5. Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p. (PubMed id 12566394)1, 2 Guy J....Jackson M.S. (Genome Res. 2003)
    6. Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering. (PubMed id 2014798)1, 3 Huebner K....Thiesen H.J. (Am. J. Hum. Genet. 1991)
    7. Multiple genes encoding zinc finger domains are expressed in human T cells. (PubMed id 2288909)1, 2 Thiesen H.-J. (New Biol. 1990)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7582 HGNC: 13097 Ensembl:ENSG00000196693 euGenes: HUgn7582 ECgene: ZNF33B
    H-InvDB: ZNF33B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZNF33B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZNF33B gene:
    Search GeneIP for patents involving ZNF33B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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