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Aliases for ZNF33A Gene

Aliases for ZNF33A Gene

  • Zinc Finger Protein 33A 2 3
  • Zinc Finger Protein 11A 2 3 4
  • Zinc Finger And ZAK-Associated Protein With KRAB Domain 3 4
  • Zinc Finger Protein 33a (KOX 31) 2 3
  • Zinc Finger Protein KOX31 3 4
  • ZNF11A 3 4
  • KOX31 3 4
  • ZZAPK 3 4
  • ZNF33 3 4
  • NF11A 3 6
  • ZNF11 3 4
  • KOX2 3 6
  • Zinc Finger And ZAK Associated Protein With KRAB Domain 2
  • Brain My041 Protein 3
  • KIAA0065 4
  • KOX5 3

External Ids for ZNF33A Gene

Previous HGNC Symbols for ZNF33A Gene

  • ZNF33
  • ZNF11A

Previous GeneCards Identifiers for ZNF33A Gene

  • GC10P038322
  • GC10P038189
  • GC10P038177
  • GC10P038339

Summaries for ZNF33A Gene

GeneCards Summary for ZNF33A Gene

ZNF33A (Zinc Finger Protein 33A) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF630.

UniProtKB/Swiss-Prot for ZNF33A Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF33A Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF33A Gene

Genomics for ZNF33A Gene

Genomic Location for ZNF33A Gene

Start:
38,010,650 bp from pter
End:
38,065,088 bp from pter
Size:
54,439 bases
Orientation:
Plus strand

Genomic View for ZNF33A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF33A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF33A Gene

No data available for Regulatory Elements for ZNF33A Gene

Proteins for ZNF33A Gene

  • Protein details for ZNF33A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q06730-ZN33A_HUMAN
    Recommended name:
    Zinc finger protein 33A
    Protein Accession:
    Q06730
    Secondary Accessions:
    • A8K9X9
    • B4E0M8
    • F6TH33
    • F8WAJ5
    • P17013
    • Q5VZ86

    Protein attributes for ZNF33A Gene

    Size:
    810 amino acids
    Molecular mass:
    94384 Da
    Quaternary structure:
    • Interacts with MLTK/ZAK.

    Alternative splice isoforms for ZNF33A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF33A Gene

Proteomics data for ZNF33A Gene at MOPED

Post-translational modifications for ZNF33A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF33A Gene

Domains for ZNF33A Gene

Gene Families for ZNF33A Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Graphical View of Domain Structure for InterPro Entry

Q06730

UniProtKB/Swiss-Prot:

ZN33A_HUMAN :
  • Q06730
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 16 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF33A: view

Function for ZNF33A Gene

Molecular function for ZNF33A Gene

GENATLAS Biochemistry: zinc finger protein 33a (KOX31) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF33A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity NAS 8464732
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF33A: view

Phenotypes for ZNF33A Gene

GenomeRNAi human phenotypes for ZNF33A:
genes like me logo Genes that share phenotypes with ZNF33A: view

Animal Model Products

CRISPR Products

miRNA for ZNF33A Gene

miRTarBase miRNAs that target ZNF33A

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF33A Gene

Localization for ZNF33A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF33A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF33A Gene COMPARTMENTS Subcellular localization image for ZNF33A gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF33A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus NAS 8464732
genes like me logo Genes that share ontologies with ZNF33A: view

Pathways for ZNF33A Gene

SuperPathways for ZNF33A Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF33A: view

Pathways by source for ZNF33A Gene

2 Reactome pathways for ZNF33A Gene

Gene Ontology (GO) - Biological Process for ZNF33A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated NAS 8464732
genes like me logo Genes that share ontologies with ZNF33A: view

Transcripts for ZNF33A Gene

Unigene Clusters for ZNF33A Gene

Zinc finger protein 33A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF33A

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF33A
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF33A Gene

No ASD Table

Relevant External Links for ZNF33A Gene

GeneLoc Exon Structure for
ZNF33A
ECgene alternative splicing isoforms for
ZNF33A

Expression for ZNF33A Gene

mRNA expression in normal human tissues for ZNF33A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF33A Gene

SOURCE GeneReport for Unigene cluster for ZNF33A Gene Hs.435774

genes like me logo Genes that share expressions with ZNF33A: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF33A Gene

Orthologs for ZNF33A Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF33A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF33A 35
  • 98.69 (n)
  • 98.03 (a)
ZNF33A 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 82 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 80 (a)
OneToMany
LOC488951 35
  • 83.69 (n)
  • 78.14 (a)
mouse
(Mus musculus)
Mammalia Gm13212 36
  • 40 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 41 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 38 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 36
  • 37 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 53 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii si:dkey-54f18.1 36
  • 44 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG3941 37
  • 32 (a)
CG5245 37
  • 40 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 33 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
-- 36
  • 42 (a)
ManyToMany
Species with no ortholog for ZNF33A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF33A Gene

ENSEMBL:
Gene Tree for ZNF33A (if available)
TreeFam:
Gene Tree for ZNF33A (if available)

Paralogs for ZNF33A Gene

Selected SIMAP similar genes for ZNF33A Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for ZNF33A Gene

genes like me logo Genes that share paralogs with ZNF33A: view

Variants for ZNF33A Gene

Sequence variations from dbSNP and Humsavar for ZNF33A Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs471741 -- 38,038,520(+) ATTTT(C/T)TATAT intron-variant
rs494278 -- 38,035,822(+) ctttc(A/T)taaaa intron-variant
rs517147 -- 38,036,040(+) accac(A/C)cacta intron-variant
rs527163 -- 38,046,562(+) actta(C/T)aggaa intron-variant
rs531444 -- 38,023,002(+) gtgca(G/T)tggtg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF33A Gene

Variant ID Type Subtype PubMed ID
nsv895030 CNV Loss 21882294

Relevant External Links for ZNF33A Gene

HapMap Linkage Disequilibrium report
ZNF33A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF33A Gene

Disorders for ZNF33A Gene

(1) University of Copenhagen DISEASES for ZNF33A Gene

genes like me logo Genes that share disorders with ZNF33A: view

No data available for UniProtKB/Swiss-Prot for ZNF33A Gene

Publications for ZNF33A Gene

  1. Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution. (PMID: 8464732) Tunnacliffe A. … Ponder B.A. (Nucleic Acids Res. 1993) 2 3 4 23
  2. Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering. (PMID: 2014798) Huebner K. … Thiesen H.J. (Am. J. Hum. Genet. 1991) 2 3
  3. Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 7584044) Nomura N. … Tabata S. (DNA Res. 1994) 3 4
  4. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  5. A novel zinc finger protein, ZZaPK, interacts with ZAK and stimulates the ZAK-expressing cells re-entering the cell cycle. (PMID: 12535642) Yang J.-J. (Biochem. Biophys. Res. Commun. 2003) 3 4

Products for ZNF33A Gene

Sources for ZNF33A Gene

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