ZNF337 Gene
protein-coding GIFtS: 50
GCID: GC20M025654
|
|
zinc finger protein 337
| |
Aliases
for ZNF337 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 3371 2 | | DJ694B14.11 |
Export aliases for ZNF337 gene to outside databasesPrevious GC identifers: GC20M025642 GC20M025649 GC20M025602 GC20M025612 |
Summaries
for ZNF337 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN337_HUMAN, Q9Y3M9Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF337 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZNF337
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF337
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF337 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p11.1 Ensembl cytogenetic band: 20p11.1 HGNC chromosome: 20ZNF337 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M025654: view genomic region
(about GC identifiers)
Start:
|
25,654,851 bp from pter |
End:
|
25,677,477 bp from pter |
Size:
|
22,627 bases |
Orientation:
|
minus strand |
|
Proteins
for ZNF337 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN337_HUMAN, Q9Y3M9 (See
protein sequence)Recommended Name: Zinc finger protein 337 Size: 751 amino acids; 86875 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q9Y3Y5Explore the universe of human proteins at neXtProt for ZNF337: NX_Q9Y3M9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y3M9
ZNF337 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_056470.1
ENSEMBL proteins: ENSP00000365619 ENSP00000252979 ENSP00000442181 Reactome Protein details: Q9Y3M9
Human Recombinant Protein Products for ZNF337:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF337 for ontologies About GeneDecksing
ZNF337 Antibody Products:
Assay Products for ZNF337: |
Protein
Domains /
Families
for ZNF337 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF337 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y3M9ProtoNet protein and cluster: Q9Y3M9 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN337_HUMAN, Q9Y3M9Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 20 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF337 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZN337_HUMAN, Q9Y3M9Function: May be involved in transcriptional regulation Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF337 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for ZNF337:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF337
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF337
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF337 (NM_015655) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF337 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF337 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF337 |
|
Pathways & Interactions
for ZNF337 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF337
ZNF337 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF337
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
5/7 Interacting proteins for ZNF337 (Q9Y3M92, 3 ENSP000002529794) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF337 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF337 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF337
Search CenterWatch for drugs/clinical trials and news about ZNF337 / ZN337
|
Transcripts
for ZNF337 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF337 gene: NM_015655.2 Unigene Clusters for ZNF337: Zinc finger protein 337 Hs.633621 [show with all ESTs], Hs.661684 [show with all ESTs]Unigene Representative Sequences: BC034569, BC0212984 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000376436(uc002wva.3 uc010ztg.2) ENST00000252979(uc002wvc.3)
ENST00000481610 ENST00000538750
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF337
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF337
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF337 (NM_015655) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF337 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF337 |
Additional cDNA sequence: AK056184.1 AK125455.1 AK291235.1 AK299811.1 AL049942.1 BC021298.2 19 DOTS entries: DT.436106 DT.40209791 DT.91730467 DT.97788094 DT.91709731 DT.100694901 DT.120804426 DT.120804461 DT.75121718 DT.91849430 DT.100742809 DT.100776216 DT.120804462 DT.91966628 DT.91998962 DT.97842694 DT.120804448 DT.86839648 DT.92037996 24/86 AceView cDNA sequences (see all 86): AA610123 BQ005270 AK056184 AA283641 CR621860 BQ677265 BQ683554 AI004599 BP336439 BI767915 BQ879977 AK056466 NM_015655 AI333442 BC011247 BG697869 BF062073 AJ711615 BF924550 AI381180 AI968183 AW137163 AW612771 BC021298
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF337 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | - | | - | | | | - | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | - | | - | | | | - | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF337
|
Expression
for ZNF337 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF337 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCCCTCAAC
About this image
See ZNF337 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF337
SOURCE GeneReport for Unigene clusters: Hs.633621 Hs.661684
SABiosciences Custom PCR Arrays for ZNF337
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF337
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF337 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF337 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF337 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF337 |
Orthologs
for ZNF337 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF337 gene from 1/4 species (see all 4) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
BQ481282.12 |
-- |
72.13(n) |
|
BQ481282.1 |
ENSEMBL Gene Tree for ZNF337 (if available)
TreeFam Gene Tree for ZNF337 (if available) |
Paralogs
for ZNF337 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF337 gene
- ZNF5892 ZNF1692 ZNF3432 ZNF1332 HKR12
18/508 SIMAP similar genes for ZNF337 using alignment to 2 protein entries: ZN337_HUMAN (see all proteins)
(see all similar genes):ZNF818P ZNF300P1 kr-znf3 PRMD9 ZFS-5 PRDM9
MGC12518 ZNF169 DKFZp313M0722 DKFZp434J0650 HZF36 ZNF323
ZNF844 ZSCAN23 DKFZp666C237 DKFZp686M04222 ZFP41 ZNF
ZNF337 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ZNF337
PGOHUM00000239794
|
Genomic Variants
for ZNF337 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF337 (25654851 - 25677477 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF337
1 Indel: 60361 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF337 |
|
Disorders
/ Diseases
for ZNF337 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF337 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF337 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF337) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF337 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF337 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF337 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF337 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF337 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF337 gene:
Search GeneIP for patents involving ZNF337
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF337 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF337 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF337 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF337 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF337 | | OriGene 3'-UTR Clone for ZNF337 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF337 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF337 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| |  |  |  |  | | | | |
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 | | | ZNF337 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF337 |
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