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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF335 Gene

protein-coding   GIFtS: 50
GCID: GC20M044577

Zinc Finger Protein 335

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger Protein 3351 2     NIF22 5
NRC-Interacting Factor 11 2 3     MCPH102
NIF-12 3     Zinc-Finger/Leucine-Zipper Co-Transducer NIF12
NIF12 5     

External Ids:    HGNC: 158071   Entrez Gene: 639252   Ensembl: ENSG000001980267   OMIM: 6108275   UniProtKB: Q9H4Z23   

Export aliases for ZNF335 gene to outside databases

Previous GC identifers: GC20M044305 GC20M045215 GC20M045262 GC20M044010 GC20M041318


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ZNF335 Gene:
The protein encoded by this gene enhances transcriptional activation by ligand-bound nuclear hormone receptors.
However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear
hormone receptor transcriptional coactivator NRC. The encoded protein may function by altering local chromatin
structure. (provided by RefSeq, Jul 2008)

GeneCards Summary for ZNF335 Gene: 
ZNF335 (zinc finger protein 335) is a protein-coding gene. Diseases associated with ZNF335 include microcephaly. GO annotations related to this gene include DNA binding and zinc ion binding.

UniProtKB/Swiss-Prot: ZN335_HUMAN, Q9H4Z2
Function: Component or associated component of some histone methyltransferase complexes may regulate transcription
through recruitment of those complexes on gene promoters. Enhances ligand-dependent transcriptional activation by
nuclear hormone receptors. Plays an important role in neural progenitor cell proliferation and self-renewal
through the regulation of specific genes involved brain development, including REST. Also controls the expression
of genes involved in somatic development and regulates, for instance, lymphoblast proliferation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NT_011362.10  NC_018931.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF335 gene promoter:
         AP-1   ATF-2   RelA   NF-kappaB   CREB   NF-kappaB2   deltaCREB   c-Jun   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF335 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF335

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF335


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.12   Ensembl cytogenetic band:  20q13.12   HGNC cytogenetic band: 20q13.12

ZNF335 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF335 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M044577:  view genomic region     (about GC identifiers)

Start:
44,577,292 bp from pter      End:
44,600,833 bp from pter
Size:
23,542 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZN335_HUMAN, Q9H4Z2 (See protein sequence)
Recommended Name: Zinc finger protein 335  
Size: 1342 amino acids; 144893 Da
Subunit: Interacts with NCOA6; may enhance ligand-dependent transcriptional activation by nuclear hormone
receptors. Interacts with CNOT6. Interacts with RQCD1; the interaction is direct. Interacts with members of
histone H3'Lys4'(H3K4) methyltransferase complexes ASCL2, CXXC1, KMT2A/MLL1, RBBP5, SETD1A and WDR5. Part of a
complex composed at least of ASCL2, C11orf30/EMSY, HCFC1, HSPA8, KIAA1967, MATR3, MKI67, RBBP5, TUBB2A, WDR5 and
ZNF335; this complex may have a histone H3-specific methyltransferase activity
Subcellular location: Nucleus
Developmental stage: Widely expressed in fetal tissues including fetal brain
Sequence caution: Sequence=BAB15379.1; Type=Erroneous initiation;
Secondary accessions: B4DLG7 Q548D0 Q9H684
Alternative splicing: 2 isoforms:  Q9H4Z2-1   Q9H4Z2-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZNF335: NX_Q9H4Z2

Explore proteomics data for ZNF335 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H4Z2

  • ZNF335 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZNF335 Protein Expression
    REFSEQ proteins: NP_071378.1  
    ENSEMBL proteins: 
     ENSP00000325326   ENSP00000397098  

    Human Recombinant Protein Products for ZNF335: 
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    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0035097colocalizes with histone methyltransferase complex IDA--

    ZNF335 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZNF: Zinc fingers, C2H2-type

    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q9H4Z2

    ProtoNet protein and cluster: Q9H4Z2

    UniProtKB/Swiss-Prot: ZN335_HUMAN, Q9H4Z2
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 13 C2H2-type zinc fingers


    ZNF335 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN335_HUMAN, Q9H4Z2
    Function: Component or associated component of some histone methyltransferase complexes may regulate transcription
    through recruitment of those complexes on gene promoters. Enhances ligand-dependent transcriptional activation by
    nuclear hormone receptors. Plays an important role in neural progenitor cell proliferation and self-renewal
    through the regulation of specific genes involved brain development, including REST. Also controls the expression
    of genes involved in somatic development and regulates, for instance, lymphoblast proliferation

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18180299
    GO:0008270zinc ion binding ----
    GO:0044212transcription regulatory region DNA binding ISS--
    GO:0046872metal ion binding IEA--
         
    ZNF335 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Zfp335):
     mortality/aging  nervous system  no phenotypic analysis 

    ZNF335 for phenotypes           About GeneDecksing

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ZNF335

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/10 Interacting proteins for ZNF335 (Q9H4Z23 ENSP000003253264) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ASH2LQ9UBL33, ENSP000003408964I2D: score=1 STRING: ENSP00000340896
    CCAR2Q8N1633, ENSP000003106704I2D: score=1 STRING: ENSP00000310670
    HCFC1P516103, ENSP000003095554I2D: score=1 STRING: ENSP00000309555
    MDM2Q009873, ENSP000004172814I2D: score=1 STRING: ENSP00000417281
    RBBP5Q152913, ENSP000002645154I2D: score=1 STRING: ENSP00000264515
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002052positive regulation of neuroblast proliferation ISS--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0007420brain development IMP--
    GO:0040029regulation of gene expression, epigenetic IMP--

    ZNF335 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF335 (ZN335)

    Search CenterWatch for drugs/clinical trials and news about ZNF335 / ZN335

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZNF335 gene: 
    NM_022095.3  

    Unigene Cluster for ZNF335:

    Zinc finger protein 335
    Hs.174193  [show with all ESTs]
    Unigene Representative Sequence: NM_022095
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000322927(uc002xqv.3 uc002xqw.3) ENST00000475002 ENST00000476822(uc002xqx.1)
    ENST00000494955(uc002xqy.3) ENST00000426788(uc010zxk.2)
    miRNA
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    hsa-miR-596 hsa-miR-204 hsa-miR-149 hsa-miR-513a-3p hsa-miR-3672 hsa-miR-211
    SwitchGear 3'UTR luciferase reporter plasmidZNF335 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF335

    Additional mRNA sequence: 

    AF395833.1 AK026157.1 AK074214.1 AK296989.1 BC041331.2 BC113115.1 BC142981.1 

    22 DOTS entries:

    DT.100020888  DT.444208  DT.95247475  DT.97840891  DT.120817676  DT.101966379  DT.102828445  DT.75198335 
    DT.91708971  DT.100811349  DT.99930614  DT.109223  DT.95254714  DT.120817423  DT.120817454  DT.120817638 
    DT.120817651  DT.120817862  DT.91749425  DT.95085724  DT.95147623  DT.95269465 

    24/110 AceView cDNA sequences (see all 110):

    AL449706 AL601174 AK074214 BM701356 BE857941 BF055175 NM_022095 AI685320 
    BF115665 AA358671 AI936904 BE676476 AI122697 AW572287 BI022583 AI521190 
    BX645376 AF395833 AK026157 BM802387 BU187475 AI803095 AI457728 AW013987 

    GeneLoc Exon Structure

    5/22 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF335 (see all 22)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b · 10c · 10d ^ 11a · 11b ^
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 12a · 12b ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b · 16c · 16d ^ 17a · 17b ^ 18a · 18b ^ 19a · 19b ^ 20 ^ 21a · 21b · 21c · 21d ^ 22a · 22b ^ 23 ^ 24 ^ 25 ^
    SP1:                                                                          -           -                                         -                           
    SP2:                                                                                                                                -                           
    SP3:                                                                          -           -                                                                     
    SP4:                                                                                                                                                            
    SP5:                                                                                      -                                                                     

    ExUns: 26 ^ 27a · 27b ^ 28 ^ 29a · 29b
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for ZNF335

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF335 expression in normal human tissues (normalized intensities)      ZNF335 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGGGTGCCC
    ZNF335 Expression
    About this image


    ZNF335 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Intermediate Mesoderm (Gastrulation Derivatives)
             Intermediate Mesoderm

    See ZNF335 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF335

    SOURCE GeneReport for Unigene cluster: Hs.174193

    UniProtKB/Swiss-Prot: ZN335_HUMAN, Q9H4Z2
    Tissue specificity: Ubiquitously expressed

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF335

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ZNF335 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp3351 , 5 zinc finger protein 3351, 5 85.25(n)1
    87.83(a)1
      2 (85.27 cM)5
    3295591  NM_199027.21  NP_950192.21 
     1648918825 
    chicken
    (Gallus gallus)
    Aves ZNF3351 zinc finger protein 335 68.29(n)
    67.52(a)
      396131  NM_205210.2  NP_990541.2 
    lizard
    (Anolis carolinensis)
    Reptilia ZNF3356
    --
    (see all 3)
    Uncharacterized protein
    (see all 3)
    81(a)
    46(a)
    (see all 3)
    1 ↔ 1
    possible ortholog
    (see all 3)
    GL343741.1(154149-164739)
    GL343741.1(178616-193522)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.275432 Xenopus laevis transcribed sequence with moderate similarity more 78.64(n)    BX846432.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1001488911 zinc finger protein 335-like 61.87(n)
    59.22(a)
      100148891  XM_003199087.1  XP_003199135.1 


    ENSEMBL Gene Tree for ZNF335 (if available)
    TreeFam Gene Tree for ZNF335 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF335 gene
    7 SIMAP similar genes for ZNF335 using alignment to 2 protein entries:     ZN335_HUMAN (see all proteins):
    ZNF    ZNF702P    DKFZp434J0650    ZNF600    ZNF697    ZNF78L1
    ZNF72

    ZNF335 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/812 SNPs in ZNF335 are shown (see all 812)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0694694
    Microcephaly, primary, 10 (MCPH10)4--see VAR_0694692 R H mis40--------
    rs339874971,2
    C--41324900(+) TTTTT-/T/TT  
            
    GAGAC
    1 -- int11NA 2
    rs741768381,2
    C--41340874(+) TTGCGT/-TTTTT 1 -- int11Minor allele frequency- -:0.50NA 2
    rs2000733201,2
    --41340880(+) TTTTT-/GTTTTT 1 -- int10--------
    rs731285611,2
    C,F--41340881(+) TTTTTC/G/TTTTTT 1 -- int12CSA WA 120
    rs1485613071,2
    --44547238(+) CCTGGA/TGGCCT 1 -- ds50010--------
    rs1169678231,2
    C,F--44547264(+) AGGTCC/TGAAGA 1 -- ds50011Minor allele frequency- T:0.04EA 120
    rs1894962951,2
    --44547306(+) TCCCCC/TAGCAG 1 -- ds50010--------
    rs1419322981,2
    --44547320(+) CTGTAC/TGGATA 1 -- ds50010--------
    rs1168455321,2
    F--44547322(+) GTATGG/AATACC 1 -- ds50011Minor allele frequency- A:0.01NA 120

    HapMap Linkage Disequilibrium report for ZNF335 (44577292 - 44600833 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ZNF335:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1000107CNV Deletion20482838
    nsv180559CNV Loss16902084
    nsv912896CNV Loss21882294
    nsv833991CNV Loss17160897
    dgv4571n71CNV Loss21882294
    nsv517296CNV Loss19592680


    Human Gene Mutation Database (HGMD): ZNF335
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF335
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF335

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610827    OMIM disorders: --

    UniProtKB/Swiss-Prot: ZN335_HUMAN, Q9H4Z2
  • Microcephaly, primary, 10 (MCPH10) [MIM:615095]: A form of microcephaly, a disease defined as a head
    circumference more than 3 standard deviations below the age-related mean. Brain weight is markedly reduced and
    the cerebral cortex is disproportionately small. MCPH10 is characterized by extremely small head size and death
    usually by 1 year of age. Neuropathologic examination shows severe loss of neurons as well as neuronal loss of
    polarity and abnormal dendritic maturation. Note=The disease is caused by mutations affecting the gene
    represented in this entry

  • 2 diseases for ZNF335:    About MalaCards
    microcephaly    


    ZNF335 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZNF335
    Human Genome Epidemiology (HuGE) Navigator: ZNF335 (1 document)

    Export disorders for ZNF335 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF335 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with ZNF335)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. NRC-interacting factor 1 is a novel cotransducer that interacts with and regulates the activity of the nuclear hormone receptor coactivator NRC. (PubMed id 12215545)1, 2, 3, 9 Mahajan M.A.... Samuels H.H. (2002)
    2. Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation. (PubMed id 19131338)1, 2, 3, 9 Garapaty S....Samuels H.H. (2009)
    3. Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1. (PubMed id 18180299)1, 2, 9 Garapaty S....Samuels H.H. (2008)
    4. Microcephaly gene links trithorax and REST/NRSF to con trol neural stem cell proliferation and differentiation. (PubMed id 23178126)1, 2 Yang Y.J....Walsh C.A. (2012)
    5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    8. A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells. (PubMed id 22094256)1 Anders L....Sicinski P. (2011)
    9. Complementary quantitative proteomics reveals that tr anscription factor AP-4 mediates E-box-dependent complex formation for transcri ptional repression of HDM2. (PubMed id 19505873)1 Ku W.C....Chen Y.J. (2009)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 63925 HGNC: 15807 AceView: ZNF335 Ensembl:ENSG00000198026 euGenes: HUgn63925
    ECgene: ZNF335 H-InvDB: ZNF335

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF335 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZNF335 gene:
    Search GeneIP for patents involving ZNF335

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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