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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ZNF335 Gene

protein-coding GIFtS: 48
GCID: GC20M044577

zinc finger protein 335

Search for ZNF335
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Zinc Finger Protein 335¹ ²		NIF2² ⁵
NIF-1¹ ² ³		BA465L10.2¹
NRC-Interacting Factor 1² ³		Zinc-Finger/Leucine-Zipper Co-Transducer NIF1²
NIF1² ⁵

External Ids:	HGNC: 15807¹	Entrez Gene: 63925²	Ensembl: ENSG00000198026⁷	OMIM: 610827⁵	UniProtKB: Q9H4Z2³

Export aliases for ZNF335 gene to outside databases

Previous GC identifers: GC20M044305 GC20M045215 GC20M045262 GC20M044010 GC20M041318

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ZNF335:

The protein encoded by this gene enhances transcriptional activation by ligand-bound nuclear hormone receptors.

However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear hormone

receptor transcriptional coactivator NRC. The encoded protein may function by altering local chromatin structure.

(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ZN335_HUMAN, Q9H4Z2

Function: Enhances ligand-dependent transcriptional activation by nuclear hormone receptors. This effect may be

mediated by NCOA6

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000020.10 NC_018931.1 NT_011362.10

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ZNF335 gene promoter:
AP-1 ATF-2 RelA NF-kappaB CREB NF-kappaB2 deltaCREB c-Jun NF-kappaB1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZNF335 promoter sequence

Search SABiosciences Chromatin IP Primers for ZNF335

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF335

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.12 Ensembl cytogenetic band: 20q13.12 HGNC cytogenetic band: 20q13.12

ZNF335 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF335 gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20M044577: view genomic region (about GC identifiers)

Start:	44,577,292 bp from pter	End:	44,600,833 bp from pter
Size:	23,542 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ZN335_HUMAN, Q9H4Z2 (See protein sequence)

Recommended Name: Zinc finger protein 335

Size: 1342 amino acids; 144893 Da

Subunit: Interacts with NCOA6, but not with ligand-bound nuclear hormone receptors, including ESR1, THRA, RARA, RXRA,

GCCR and PPARA. Interacts with CNOT6. Directly interacts with RQCD1

Subcellular location: Nucleus

Sequence caution: Sequence=BAB15379.1; Type=Erroneous initiation;

Secondary accessions: B4DLG7 Q548D0 Q9H684

Alternative splicing: 2 isoforms: Q9H4Z2-1 Q9H4Z2-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZNF335: NX_Q9H4Z2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9H4Z2

ZNF335 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_071378.1

ENSEMBL proteins:

ENSP00000325326 ENSP00000397098

Human Recombinant Protein Products for ZNF335:

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	Uscn Proteins for ZNF335

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

ZNF335 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZNF335 for domains About GeneDecksing

3 InterPro domains/families:

IPR015880 Znf_C2H2-like

IPR013087 Znf_C2H2/integrase_DNA-bd

IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q9H4Z2

ProtoNet protein and cluster: Q9H4Z2

UniProtKB/Swiss-Prot: ZN335_HUMAN, Q9H4Z2

Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family

Similarity: Contains 13 C2H2-type zinc fingers

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: ZN335_HUMAN, Q9H4Z2

Function: Enhances ligand-dependent transcriptional activation by nuclear hormone receptors. This effect may be

mediated by NCOA6

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0005515	protein binding	IPI	18180299
GO:0008270	zinc ion binding	IEA	--

ZNF335 for ontologies About GeneDecksing

Animal Models:

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		hsa-miR-596 hsa-miR-204 hsa-miR-149 hsa-miR-513a-3p hsa-miR-3672 hsa-miR-211
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF335

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for ZNF335

STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

5/10 Interacting proteins for ZNF335 (Q9H4Z2³ ENSP00000325326⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 10)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ASH2L	Q9UBL3³, ENSP00000340896⁴	I2D: score=1 STRING: ENSP00000340896
HCFC1	P51610³, ENSP00000309555⁴	I2D: score=1 STRING: ENSP00000309555
KIAA1967	Q8N163³, ENSP00000310670⁴	I2D: score=1 STRING: ENSP00000310670
MDM2	Q00987³, ENSP00000417281⁴	I2D: score=1 STRING: ENSP00000417281
RBBP5	Q15291³, ENSP00000264515⁴	I2D: score=1 STRING: ENSP00000264515

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--

ZNF335 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZNF335
Search CenterWatch for drugs/clinical trials and news about ZNF335 / ZN335

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ZNF335 gene:

NM_022095.3

Unigene Cluster for ZNF335:

Zinc finger protein 335

Hs.174193 [show with all ESTs]

Unigene Representative Sequence: NM_022095

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000322927(uc002xqv.3 uc002xqw.3) ENST00000475002 ENST00000476822(uc002xqx.1)

ENST00000494955(uc002xqy.3) ENST00000426788(uc010zxk.2)

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Additional cDNA sequence:

AF395833.1 AK026157.1 AK074214.1 AK296989.1 BC041331.2 BC113115.1 BC142981.1

22 DOTS entries:

DT.100020888 DT.444208 DT.95247475 DT.97840891 DT.120817676 DT.101966379 DT.102828445 DT.75198335

DT.91708971 DT.100811349 DT.99930614 DT.109223 DT.95254714 DT.120817423 DT.120817454 DT.120817638

DT.120817651 DT.120817862 DT.91749425 DT.95085724 DT.95147623 DT.95269465

24/110 AceView cDNA sequences (see all 110):

AI521190 AL601174 BF055175 AA358671 BF115665 BM701356 AL449706 AW572287

AI803095 AK074214 AW013987 BE676476 BU187475 AI122697 BI022583 AI457728

AI936904 BE857941 BX645376 BM802387 AK026157 NM_022095 AI685320 AF395833

GeneLoc Exon Structure

5/22 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF335 (see all 22) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	·	2c	^	3a	·	3b	·	3c	^	4a	·	4b	·	4c	·	4d	^	5	^	6	^	7	^	8a	·	8b	^	9a	·	9b	·	9c	^	10a	·	10b	·	10c	·	10d	^	11a	·	11b	^
SP1:
SP2:
SP3:
SP4:
SP5:

ExUns:	12a	·	12b	^	13	^	14	^	15a	·	15b	^	16a	·	16b	·	16c	·	16d	^	17a	·	17b	^	18a	·	18b	^	19a	·	19b	^	20	^	21a	·	21b	·	21c	·	21d	^	22a	·	22b	^	23	^	24	^	25	^
SP1:																									-				-														-
SP2:																																											-
SP3:																									-				-
SP4:
SP5:																													-

ExUns:	26	^	27a	·	27b	^	28	^	29a	·	29b
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for ZNF335

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZNF335 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGGGTGCCC

About this image

ZNF335 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Kidney

Metanephric Mesenchyme

Metanephric Mesenchyme Cells

Kidney

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ZNF335 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF335

SOURCE GeneReport for Unigene cluster: Hs.174193

UniProtKB/Swiss-Prot: ZN335_HUMAN, Q9H4Z2

Tissue specificity: Relatively high expression in the skeletal muscle, thymus, placenta and blood. Moderate expression

in the colon, kidney and lung. Low expression in the small intestine, heart, liver and brain

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for ZNF335 gene from 5/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Zfp335^{1 , 5}	zinc finger protein 335^{1, 5}	85.25(n)¹ 87.83(a)¹		2 (85.27 cM)⁵ 329559¹ NM_199027.2¹ NP_950192.2¹ 164891882⁵
chicken (Gallus gallus)	Aves	ZNF335¹	zinc finger protein 335	68.29(n) 67.52(a)		396131 NM_205210.2 NP_990541.2
lizard (Anolis carolinensis)	Reptilia	-- --	--	81(a) 47(a)	many → 1 many → 1	GL343741.1(154149-164730) GL343741.1(178616-193304)
African clawed frog (Xenopus laevis)	Amphibia	Xl.27543²	Xenopus laevis transcribed sequence with moderate similarity more	78.64(n)		BX846432.1
zebrafish (Danio rerio)	Actinopterygii	LOC100148891¹	zinc finger protein 335-like	61.87(n) 59.22(a)		100148891 XM_003199087.1 XP_003199135.1

ENSEMBL Gene Tree for ZNF335 (if available)
TreeFam Gene Tree for ZNF335 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Pop	Total sample
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs6130975^1,2	C,F,A,H	--	41318451(+)	`TGAGCG/AAAGAG`	1	--	ds500¹		5	NS EA WA	528
rs35291173^1,2	C,F	--	41319336(-)	`TCCCCA/GGGCCA`	2	P	syn¹		3	NA EU	5907
rs111937962^1,2	F	--	41319882(+)	`CTGAGG/AGGATT`	1	--	int¹		1	CSA	4
rs112742470^1,2		--	41321160(+)	`CACACT/CTGGCT`	1	--	int¹		1	CSA	1
rs34240177^1,2	C,F	--	41321759(+)	`CTGCTC/G/TTGACA`	1	--	int¹		5	NA WA EA	362
rs11696623^1,2	C,F,H	--	41321849(+)	`gactaC/Tcagtc`	1	--	int¹		10	NS EA NA WA	666
rs73911136^1,2	C	--	41321861(+)	`ATGGCC/GCAGGG`	1	--	int¹		2	WA	120
rs6017714^1,2	H	--	41322869(+)	`GCCCCC/TTTCCC`	1	--	int¹ trp³		4	NS EA	410
rs6124760^1,2	C,F,H	--	41322922(+)	`GGACTC/GAAGTC`	1	--	int¹		10	NS EA NA WA	798
rs73293599^1,2	C	--	41323202(+)	`TGGCCG/ACCCAG`	1	--	int¹		2	WA	120

HapMap Linkage Disequilibrium report for ZNF335 (44577292 - 44600833 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ZNF335
3 CNVs: 6113 50668 50669
Human Gene Mutation Database (HGMD): ZNF335

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF335

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ZNF335 for disorders About MalaCards

ZNF335 for disorders About GeneDecksing

OMIM gene information: 610827 OMIM disorders: --

Human Genome Epidemiology (HuGE) Navigator: ZNF335 (1 document)

Export disorders for ZNF335 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ZNF335 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with ZNF335)

Utopia: connect your pdf to the dynamic
world of online information

NRC-interacting factor 1 is a novel cotransducer that interacts with and regulates the activity of the nuclear hormone receptor coactivator NRC. (PubMed id 12215545)^{1, 2, 3, 9} Mahajan M.A.... Samuels H.H. (2002)
Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation. (PubMed id 19131338)^{1, 3, 9} Garapaty S....Samuels H.H. (2009)
Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1. (PubMed id 18180299)^{1, 2, 9} Garapaty S....Samuels H.H. (2008)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (2001)
Microcephaly gene links trithorax and REST/NRSF to con trol neural stem cell proliferation and differentiation. (PubMed id 23178126)¹ Yang Y.J....Walsh C.A. (2012)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Complementary quantitative proteomics reveals that tr anscription factor AP-4 mediates E-box-dependent complex formation for transcri ptional repression of HDM2. (PubMed id 19505873)¹ Ku W.C....Chen Y.J. (2009)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PubMed id 17525332)² Matsuoka S.... Elledge S.J. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 63925	HGNC: 15807	AceView: ZNF335	Ensembl:ENSG00000198026	euGenes: HUgn63925
ECgene: ZNF335	H-InvDB: ZNF335

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ZNF335	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ZNF335 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ZNF335 gene:
Search GeneIP for patents involving ZNF335

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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ZNF335 Gene

zinc finger protein 335

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ZNF335 Gene

zinc finger protein 335

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