Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF333 Gene

Aliases for ZNF333 Gene

  • Zinc Finger Protein 333 2 3 5
  • KIAA1806 4

External Ids for ZNF333 Gene

Previous GeneCards Identifiers for ZNF333 Gene

  • GC19P015169
  • GC19P014646
  • GC19P014800
  • GC19P014367

Summaries for ZNF333 Gene

GeneCards Summary for ZNF333 Gene

ZNF333 (Zinc Finger Protein 333) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF891.

UniProtKB/Swiss-Prot for ZNF333 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF333 Gene

Genomics for ZNF333 Gene

Regulatory Elements for ZNF333 Gene

Enhancers for ZNF333 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ZNF333 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF333 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF333 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF333 Gene

Chromosome:
19
Start:
14,689,787 bp from pter
End:
14,733,746 bp from pter
Size:
43,960 bases
Orientation:
Plus strand

Genomic View for ZNF333 Gene

Genes around ZNF333 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF333 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF333 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF333 Gene

Proteins for ZNF333 Gene

  • Protein details for ZNF333 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96JL9-ZN333_HUMAN
    Recommended name:
    Zinc finger protein 333
    Protein Accession:
    Q96JL9
    Secondary Accessions:
    • Q6P2E6
    • Q86WS6
    • Q8TDL0

    Protein attributes for ZNF333 Gene

    Size:
    665 amino acids
    Molecular mass:
    75544 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF333 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF333 Gene

Post-translational modifications for ZNF333 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF333 Gene

No data available for DME Specific Peptides for ZNF333 Gene

Domains & Families for ZNF333 Gene

Gene Families for ZNF333 Gene

Protein Domains for ZNF333 Gene

Graphical View of Domain Structure for InterPro Entry

Q96JL9

UniProtKB/Swiss-Prot:

ZN333_HUMAN :
  • Contains 2 KRAB domains.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
Domain:
  • Contains 2 KRAB domains.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF333: view

Function for ZNF333 Gene

Molecular function for ZNF333 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF333 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF333: view
genes like me logo Genes that share phenotypes with ZNF333: view

Animal Model Products

CRISPR Products

miRNA for ZNF333 Gene

miRTarBase miRNAs that target ZNF333

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF333 Gene

Localization for ZNF333 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF333 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF333 Gene COMPARTMENTS Subcellular localization image for ZNF333 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF333 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF333: view

Pathways & Interactions for ZNF333 Gene

SuperPathways for ZNF333 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF333: view

Pathways by source for ZNF333 Gene

2 Reactome pathways for ZNF333 Gene

Gene Ontology (GO) - Biological Process for ZNF333 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF333: view

No data available for SIGNOR curated interactions for ZNF333 Gene

Drugs & Compounds for ZNF333 Gene

No Compound Related Data Available

Transcripts for ZNF333 Gene

Unigene Clusters for ZNF333 Gene

Zinc finger protein 333:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF333 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14 ^ 15
SP1: - - - - - -
SP2: - -
SP3: - -
SP4:
SP5:

Relevant External Links for ZNF333 Gene

GeneLoc Exon Structure for
ZNF333
ECgene alternative splicing isoforms for
ZNF333

Expression for ZNF333 Gene

mRNA expression in normal human tissues for ZNF333 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF333 Gene



NURSA nuclear receptor signaling pathways regulating expression of ZNF333 Gene:

ZNF333

SOURCE GeneReport for Unigene cluster for ZNF333 Gene:

Hs.515215

mRNA Expression by UniProt/SwissProt for ZNF333 Gene:

Q96JL9-ZN333_HUMAN
Tissue specificity: Highly expressed in heart.
genes like me logo Genes that share expression patterns with ZNF333: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Protein tissue co-expression partners for ZNF333 Gene

Orthologs for ZNF333 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF333 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF333 34
  • 76.14 (n)
  • 68.27 (a)
ZNF333 35
  • 68 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF333 34
  • 81.86 (n)
  • 78.37 (a)
ZNF333 35
  • 78 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF333 34
  • 99 (n)
  • 98.8 (a)
ZNF333 35
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 35 (a)
ManyToMany
-- 35
  • 41 (a)
ManyToMany
-- 35
  • 32 (a)
ManyToMany
-- 35
  • 30 (a)
ManyToMany
-- 35
  • 39 (a)
ManyToMany
-- 35
  • 46 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm14444 35
  • 32 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 28 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ZNF557 35
  • 22 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG10366 36
  • 34 (a)
CG17568 36
  • 34 (a)
CG6254 36
  • 38 (a)
Kr 36
  • 48 (a)
Species where no ortholog for ZNF333 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF333 Gene

ENSEMBL:
Gene Tree for ZNF333 (if available)
TreeFam:
Gene Tree for ZNF333 (if available)

Paralogs for ZNF333 Gene

Paralogs for ZNF333 Gene

(498) SIMAP similar genes for ZNF333 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with ZNF333: view

Variants for ZNF333 Gene

Sequence variations from dbSNP and Humsavar for ZNF333 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs3885179 - 14,717,018(-) ACAAC(A/G/T)CATTG reference, missense
rs3764626 - 14,718,937(+) GTGCG(C/T)GACTT intron-variant, downstream-variant-500B, reference, missense
rs3072548 -- 14,694,742(+) TTAAA(A/G)GAAAG intron-variant
rs3074271 -- 14,694,743(-) GTTTA(-/CTTTC)TTTTA intron-variant
rs3752185 -- 14,717,925(+) TGTTC(A/G)TACAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF333 Gene

Variant ID Type Subtype PubMed ID
esv3893167 CNV gain 25118596
nsv1060306 CNV loss 25217958
nsv1072329 CNV deletion 25765185
nsv1126515 CNV deletion 24896259
nsv458357 CNV loss 19166990
nsv578680 CNV loss 21841781

Variation tolerance for ZNF333 Gene

Residual Variation Intolerance Score: 97.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.43; 92.80% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF333 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF333

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF333 Gene

Disorders for ZNF333 Gene

Relevant External Links for ZNF333

Genetic Association Database (GAD)
ZNF333
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF333

No disorders were found for ZNF333 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF333 Gene

Publications for ZNF333 Gene

  1. Characterization of ZNF333, a novel double KRAB domain containing zinc finger gene on human chromosome 19p13.1. (PMID: 12151103) Tian Y. … Lo W.H.Y. (Biochim. Biophys. Acta 2002) 2 3 4 65
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  3. Identification of the DNA binding element of the human ZNF333 protein. (PMID: 15607024) Jing Z. … Huang S. (J. Biochem. Mol. Biol. 2004) 3 22 65
  4. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 3 4 65
  5. Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus. (PMID: 25505242) Fernandez J. … Arhel N.J. (J. Biol. Chem. 2015) 3 65

Products for ZNF333 Gene

Sources for ZNF333 Gene

Content