ZNF333 Gene
protein-coding GIFtS: 49
GCID: GC19P014800
|
|
zinc finger protein 333
| |
Aliases for ZNF333 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 3331 2 | | KIAA18061 3 5 |
Export aliases for ZNF333 gene to outside databasesPrevious GC identifers: GC19P015169 GC19P014646 GC19P014661 GC19P014367 |
Summaries for ZNF333 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: ZN333_HUMAN, Q96JL9Function: May be involved in transcriptional regulation
|
Genomic Views for ZNF333 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for ZNF333 Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF333
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF333 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13 Ensembl cytogenetic band: 19p13.12 HGNC cytogenetic band: 19p13ZNF333 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P014800: view genomic region
(about GC identifiers)
Start:
|
14,800,613 bp from pter |
End:
|
14,844,557 bp from pter |
Size:
|
43,945 bases |
Orientation:
|
plus strand |
|
Proteins for ZNF333 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ZN333_HUMAN, Q96JL9 (See
protein sequence)Recommended Name: Zinc finger protein 333 Size: 665 amino acids; 75544 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q8TDL0Explore the universe of human proteins at neXtProt for ZNF333: NX_Q96JL9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96JL9 ZNF333 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_115809.1 ENSEMBL proteins: ENSP00000438130 ENSP00000292530 ENSP00000376713 ENSP00000439749 Reactome Protein details: Q96JL9 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF333 for ontologies About GeneDecksing
ZNF333 Antibody Products: Assay Products for ZNF333: |
Protein
Domains / Families for ZNF333 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF333 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96JL9ProtoNet protein and cluster: Q96JL9 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN333_HUMAN, Q96JL9Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 10 C2H2-type zinc fingersSimilarity: Contains 2 KRAB domains |
Function for ZNF333 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: ZN333_HUMAN, Q96JL9Function: May be involved in transcriptional regulation
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF333 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF333 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF333 (NM_032433) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF333 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF333  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF333 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF333 for ontologies About GeneDecksing
|
Pathways & Interactions for ZNF333 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources See GeneCards unified pathways Show all pathways
2
Reactome Pathways for ZNF333
ZNF333 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF333
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF333 for ontologies About GeneDecksing
|
Drugs & Compounds for ZNF333 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for ZNF333 Search CenterWatch for drugs/clinical trials and news about ZNF333 / ZN333 
|
Transcripts for ZNF333 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ZNF333 gene: NM_032433.2 Unigene Cluster for ZNF333: Zinc finger protein 333 Hs.515215 [show with all ESTs]Unigene Representative Sequence: AF3727024 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000540689 ENST00000292530(uc002mzk.4 uc002mzn.3) ENST00000392987(uc010dzq.2 uc002mzl.3) ENST00000536363(uc010dzr.1)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF333 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF333 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF333 (NM_032433) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF333 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF333  |
Additional cDNA sequence: AB058709.1 AF372702.1 AK054916.1 AK094028.1 AK095142.1 AK291471.1 AK307147.1 AK309208.1 AL832544.1 BC012344.1 BC048107.1 BC064571.1 BX647475.1 13 DOTS entries: DT.108263 DT.99948406 DT.108264 DT.204926 DT.121504097 DT.100029183 DT.99947450 DT.101968414 DT.434742 DT.100674167 DT.121504064 DT.121504088 DT.95370179 24/86 AceView cDNA sequences (see all 86): AI307687 BI767437 BI030591 AA932168 BF110328 AK094028 NM_032433 AF372702 BX281302 F10223 AA343795 AI733158 AX748419 AA502604 AB058709 BM987049 BU552772 F12605 AW157012 AK122817 CR617489 AI279806 BE677411 BE673647 GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF333 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | |
| SP1: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ZNF333
|
Expression for ZNF333 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF333 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GAGGTTGAGG
About this image See ZNF333 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ZNF333
SOURCE GeneReport for Unigene cluster: Hs.515215 UniProtKB/Swiss-Prot: ZN333_HUMAN, Q96JL9Tissue specificity: Highly expressed in heart SABiosciences Custom PCR Arrays for ZNF333
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF333 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF333 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF333 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF333 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF333 |
Orthologs for ZNF333 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF333 (if available) TreeFam Gene Tree for ZNF333 (if available)  |
Paralogs for ZNF333 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ZNF333 gene
- ZNF1772 ZNF5572 ZNF8912 ZNF3172 ZNF5582
18/488 SIMAP similar genes for ZNF333 using alignment to 8 protein entries: ZN333_HUMAN (see all proteins)
(see all similar genes):DKFZp686C13142 ZNF78L1 ZNF818P ZNF ZNF331 HZF16 HZF36 ZFS-4 ZNF833P ZNF721 DKFZp666C237 DKFZp666M039 kr-znf3 ZNF625 DKFZp686H10254 ZNF204 ZNF41 ZNF55
ZNF333 for paralogs About GeneDecksing
|
Genomic Variants for ZNF333 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 19 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF333 (14800613 - 14844557 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ZNF333: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF333 |
|
Disorders
/ Diseases for ZNF333 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF333 for disorders About MalaCards
ZNF333 for disorders About GeneDecksing
OMIM gene information: 611811
OMIM disorders: --
Export disorders for ZNF333 gene to outside databases
|
Publications for ZNF333 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF333 gene integrated from 9 sources: (articles sorted by number of sources associating them with ZNF333) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Characterization of ZNF333, a novel double KRAB domain containing zinc finger gene on human chromosome 19p13.1. (PubMed id 12151103)1, 2, 3 Tian Y.... Lo W.H.Y. (2002)
- Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2 Nagase T.... Ohara O. (2001)
- Identification of the DNA binding element of the human ZNF333 protein. (PubMed id 15607024)1, 9 Jing Z....Huang S. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin. (PubMed id 17607528)9 Oh Y. and Fung L.W. (2007)
|
External Searches for ZNF333 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ZNF333 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF333 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZNF333 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ZNF333 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF333 gene: Search GeneIP for patents involving ZNF333
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ZNF333 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF333 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF333 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF333 | | OriGene Protein Over-expression Lysate for ZNF333 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ZNF333 | | OriGene 3'-UTR Clone for ZNF333 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF333 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF333 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ZNF333 | | OriGene Custom Protein Services for ZNF333 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF333 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF333 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF333 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF333 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF333 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF333 |
| |
 |  |  |  | |
| | | Search Tocris compounds for ZNF333 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | ZNF333 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF333 |
|  |  |  | | | ThermoFisher Antibody for ZNF333 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF333 |
|
|
|
|