ZNF330 Gene
protein-coding GIFtS: 46
GCID: GC04P142142
|
|
zinc finger protein 330
| |
Aliases
for ZNF330 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 3301 2 | | NOA361 2 3 5 | | HSA65911 2 | | Nucleolar Autoantigen 362 3 | | Nucleolar Cysteine-Rich Protein2 3 | | Zinc Finger Autoantigen 3302 |
Export aliases for ZNF330 gene to outside databasesPrevious GC identifers: GC04P142719 GC04P142499 GC04P142361 GC04P137871 |
Summaries
for ZNF330 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for ZNF330
|
Genomic Views
for ZNF330 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF330 gene promoter:
NF-1 AML1a MyoD HNF-3beta NF-AT C/EBPalpha CHOP-10 Pax-3 HFH-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF330
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF330 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q31.21 Ensembl cytogenetic band: 4q31.21 HGNC cytogenetic band: 4q31.21ZNF330 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P142142: view genomic region
(about GC identifiers)
Start:
|
142,142,041 bp from pter |
End:
|
142,155,851 bp from pter |
Size:
|
13,811 bases |
Orientation:
|
plus strand |
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Proteins
for ZNF330 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN330_HUMAN, Q9Y3S2 (See
protein sequence)Recommended Name: Zinc finger protein 330 Size: 320 amino acids; 36201 Da
Subcellular location: Nucleus. Nucleus, nucleolus. Chromosome, centromere. Note=Predominantly expressed in thenucleolus. In mitosis associated with centromeres and concentrated at the midbody in cytokinesis
Secondary accessions: B2RDA3Explore the universe of human proteins at neXtProt for ZNF330: NX_Q9Y3S2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y3S2
ZNF330 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055302.1
ENSEMBL proteins: ENSP00000262990 ENSP00000422574 ENSP00000422599 ENSP00000423217 ENSP00000422966 ENSP00000422251 ENSP00000427201 ENSP00000397397
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ZNF330 for ontologies About GeneDecksing
ZNF330 Antibody Products:
Assay Products for ZNF330: |
Protein
Domains /
Families
for ZNF330 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF330 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9Y3S2ProtoNet protein and cluster: Q9Y3S2 1 Blocks protein family: IPB010531 NOA36
UniProtKB/Swiss-Prot: ZN330_HUMAN, Q9Y3S2Similarity: Belongs to the NOA36 family |
Function
for ZNF330 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF330 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF330 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: ZNF330 (NM_014487) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF330 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF330 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF330 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF330 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF330 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF330
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
4 Interacting proteins for ZNF330 (Q9Y3S21, 3 ENSP000002629904) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
ZNF330 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF330 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF330
Search CenterWatch for drugs/clinical trials and news about ZNF330 / ZN330
|
Transcripts
for ZNF330 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF330 gene: NM_014487.4 Unigene Cluster for ZNF330: Zinc finger protein 330 Hs.120766 [show with all ESTs]Unigene Representative Sequence: NM_0144879 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000262990(uc003iiq.4 uc011chl.2) ENST00000514826 ENST00000507532
ENST00000512809 ENST00000515453 ENST00000503649 ENST00000512738 ENST00000506302
ENST00000421169
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF330 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF330 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF330 (NM_014487) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF330 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF330 |
Additional cDNA sequence: AJ006591.2 AK002106.1 AK223609.1 AK294089.1 AK315463.1 BC004421.1 11 DOTS entries: DT.107606 DT.408098 DT.40308706 DT.121249958 DT.92007961 DT.100776293 DT.121249948 DT.121249953 DT.121249968 DT.95253804 DT.40120242 24/108 AceView cDNA sequences (see all 108): BC004421 BQ721470 AI680581 BX499269 AU104440 CD244602 BX103113 AI446246 AU138473 AI004972 AA367315 AI934167 AK002106 BF223168 BF725943 AI399658 BE780150 BF001698 AI867867 CD515843 BQ438965 AI245841 BG252551 BG702956
GeneLoc Exon Structure
|
Expression
for ZNF330 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF330 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ZNF330 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF330
SOURCE GeneReport for Unigene cluster: Hs.120766
UniProtKB/Swiss-Prot: ZN330_HUMAN, Q9Y3S2Tissue specificity: Widely expressed. Higher expression seen in heart and skeletal muscle
SABiosciences Custom PCR Arrays for ZNF330
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF330
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF330 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF330 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF330 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF330 |
Orthologs
for ZNF330 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF330 gene from 6/23 species (see all 23) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Zfp3301 , 5 |
zinc finger protein 3301, 5 |
89.66(n)1
95.89(a)1 |
|
8 (39.58 cM)5
309321 NM_145600.11 NP_663575.11
827636205 |
chicken
(Gallus gallus) |
Aves |
ZNF3301 |
zinc finger protein 330 |
82.29(n)
89.69(a) |
|
422453 XM_420419.2 XP_420419.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ZNF3306 |
-- |
88(a) |
1 ↔ 1 |
5(119413292-119424464) |
African clawed frog
(Xenopus laevis) |
Amphibia |
noa36-pending-prov2 |
nucleolar cysteine-rich protein |
78.81(n) |
|
BC044969.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.148802 |
Danio rerio mRNA similar to nucleolar cysteine-rich more |
76.89(n) |
|
BC046062.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Noa361 |
CG10009-PA |
61.55(n)
65.53(a) |
|
43384 NM_143365.2 NP_651622.2 |
ENSEMBL Gene Tree for ZNF330 (if available)
TreeFam Gene Tree for ZNF330 (if available) |
Paralogs
for ZNF330 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZNF330 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF330
1 CNV: 3518 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for ZNF330 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF330 for disorders About GeneDecksing
OMIM gene information: 609550
OMIM disorders: --
1  disease for ZNF330: About MalaCardsconduct disorder
Export disorders for ZNF330 gene to outside databases
|
Publications
for ZNF330 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF330 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with ZNF330) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning of a zinc finger autoantigen transiently associated with interphase nucleolus and mitotic centromeres and midbodies. Orthologous proteins with nine CXXC motifs highly conserved from nematodes to humans. (PubMed id 10593942)1, 2, 3 Bolivar J.... Valdivia M.M. (1999)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Genomic structure and chromosome location of the human gene encoding the zinc finger autoantigen ZNF330. (PubMed id 11528117)1, 3 Bolivar J....Valdivia M.M. (2001)
- Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Genome-wide association study of conduct disorder sym ptomatology. (PubMed id 20585324)1 Dick D.M....Bierut L. (2010)
|
External Searches for ZNF330 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF330 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF330 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF330 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF330 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF330 gene:
Search GeneIP for patents involving ZNF330
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF330 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF330 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF330 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF330 | | | OriGene Protein Over-expression Lysate for ZNF330 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF330 | | OriGene 3'-UTR Clone for ZNF330 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF330 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF330 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF330 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF330 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF330 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF330 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF330 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF330 |
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| |  |  |  |  | | | | |
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 | | | ZNF330 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF330 |
|  |  |  | | | | ThermoFisher Antibodies for ZNF330 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF330 |
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