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Aliases for ZNF324B Gene

Aliases for ZNF324B Gene

  • Zinc Finger Protein 324B 2 3 5

External Ids for ZNF324B Gene

Previous GeneCards Identifiers for ZNF324B Gene

  • GC19P063657
  • GC19P059047
  • GC19P059051
  • GC19P055271
  • GC19P059068
  • GC19P059080
  • GC19P059097
  • GC19P059134
  • GC19P059190
  • GC19P059230
  • GC19P059279
  • GC19P058451

Summaries for ZNF324B Gene

GeneCards Summary for ZNF324B Gene

ZNF324B (Zinc Finger Protein 324B) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF324.

UniProtKB/Swiss-Prot for ZNF324B Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF324B Gene

Genomics for ZNF324B Gene

Regulatory Elements for ZNF324B Gene

Enhancers for ZNF324B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F058517 0.9 FANTOM5 ENCODE 40.2 +101.1 101149 4.9 CREB3L1 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF263 ZNF324B CENPBD1P1 ZNF134 LOC105372483 TRIM28 ZNF549 MZF1 ZNF324 ZBTB45 ZNF584
GH19F057809 1.2 FANTOM5 ENCODE 30.1 -605.3 -605343 7.2 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 ZNF134 ZNF805 ZNF264 TRIM28 ZNF256 ZNF543 ZNF417 ZNF773 ZNF17 ENSG00000269867
GH19F058325 0.2 ENCODE 21.9 -91.7 -91690 3.6 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF134 ZNF17 ZNF549 ZNF606 ZNF773 ZNF256 ZNF417 ZNF551 ZNF548 ZNF211
GH19F057583 0.5 ENCODE 21.3 -834.6 -834588 1.4 TBP CBX3 ZNF76 ARID4B RAD21 ZBTB40 ZEB1 ETS1 GLIS2 ZNF416 ZNF549 ZNF17 ZIK1 LOC100128398 ZNF324B MZF1 ZSCAN22 ZNF606 ZNF544 ZNF551
GH19F058181 0.5 ENCODE 20.1 -235.3 -235324 2.5 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF416 ZNF134 ZNF773 ZNF550 ZNF256 ZNF543 ZNF551 ZNF549 ZNF17 ZNF417 ZNF776
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF324B on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF324B Gene

Chromosome:
19
Start:
58,418,560 bp from pter
End:
58,457,833 bp from pter
Size:
39,274 bases
Orientation:
Plus strand

Genomic View for ZNF324B Gene

Genes around ZNF324B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF324B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF324B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF324B Gene

Proteins for ZNF324B Gene

  • Protein details for ZNF324B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6AW86-Z324B_HUMAN
    Recommended name:
    Zinc finger protein 324B
    Protein Accession:
    Q6AW86
    Secondary Accessions:
    • B2RTZ6
    • Q6ZMX8
    • Q6ZS42

    Protein attributes for ZNF324B Gene

    Size:
    544 amino acids
    Molecular mass:
    60602 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF324B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF324B Gene

Post-translational modifications for ZNF324B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF324B Gene

No data available for DME Specific Peptides for ZNF324B Gene

Domains & Families for ZNF324B Gene

Gene Families for ZNF324B Gene

Suggested Antigen Peptide Sequences for ZNF324B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6AW86

UniProtKB/Swiss-Prot:

Z324B_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF324B: view

Function for ZNF324B Gene

Molecular function for ZNF324B Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF324B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF324B: view
genes like me logo Genes that share phenotypes with ZNF324B: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF324B Gene

Localization for ZNF324B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF324B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF324B Gene COMPARTMENTS Subcellular localization image for ZNF324B gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF324B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF324B: view

Pathways & Interactions for ZNF324B Gene

SuperPathways for ZNF324B Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF324B: view

Pathways by source for ZNF324B Gene

2 Reactome pathways for ZNF324B Gene

Gene Ontology (GO) - Biological Process for ZNF324B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF324B: view

No data available for SIGNOR curated interactions for ZNF324B Gene

Transcripts for ZNF324B Gene

Unigene Clusters for ZNF324B Gene

Zinc finger protein 324B:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF324B Gene

No ASD Table

Relevant External Links for ZNF324B Gene

GeneLoc Exon Structure for
ZNF324B
ECgene alternative splicing isoforms for
ZNF324B

Expression for ZNF324B Gene

mRNA expression in normal human tissues for ZNF324B Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF324B Gene:

ZNF324B

SOURCE GeneReport for Unigene cluster for ZNF324B Gene:

Hs.186970
genes like me logo Genes that share expression patterns with ZNF324B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF324B Gene

Orthologs for ZNF324B Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF324B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF324B 34 35
  • 98.43 (n)
dog
(Canis familiaris)
Mammalia -- 35
  • 65 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 61 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp324 35
  • 59 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 6 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii si:dkey-238o14.6 35
  • 34 (a)
ManyToMany
si:dkey-199m13.2 35
  • 33 (a)
ManyToMany
si:dkey-233e3.4 35
  • 32 (a)
ManyToMany
si:dkey-199m13.8 35
  • 31 (a)
ManyToMany
BX640547.1 35
  • 29 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta zfh1 35
  • 6 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea zag-1 35
  • 12 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 8 (a)
OneToMany
Species where no ortholog for ZNF324B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF324B Gene

ENSEMBL:
Gene Tree for ZNF324B (if available)
TreeFam:
Gene Tree for ZNF324B (if available)

Paralogs for ZNF324B Gene

Paralogs for ZNF324B Gene

(496) SIMAP similar genes for ZNF324B Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZNF324B: view

Variants for ZNF324B Gene

Sequence variations from dbSNP and Humsavar for ZNF324B Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10416149 -- 58,452,939(+) TAAAA(A/G)TCCAA intron-variant
rs1077420 -- 58,457,508(+) GGCCG(A/C)TCCCC utr-variant-3-prime
rs1108227 -- 58,457,560(+) TGCCT(C/T)CTCAA utr-variant-3-prime
rs111417066 -- 58,454,280(+) GAGGA(G/T)CCCTG reference, missense
rs111517488 -- 58,450,814(+) CTGCC(A/C)ACAAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF324B Gene

Variant ID Type Subtype PubMed ID
esv3556698 CNV deletion 23714750
nsv1057077 CNV gain 25217958
nsv1160670 CNV deletion 26073780
nsv515731 CNV gain+loss 19592680
nsv833888 CNV loss 17160897
nsv952155 CNV deletion 24416366

Variation tolerance for ZNF324B Gene

Residual Variation Intolerance Score: 76.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.01; 37.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF324B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF324B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF324B Gene

Disorders for ZNF324B Gene

Relevant External Links for ZNF324B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF324B

No disorders were found for ZNF324B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF324B Gene

Publications for ZNF324B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks I.A. … Vertegaal A.C. (Nat. Struct. Mol. Biol. 2014) 4 64
  3. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa R.S. … Obuse C. (Nat. Cell Biol. 2010) 3 64
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for ZNF324B Gene

Sources for ZNF324B Gene

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