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Aliases for ZNF324B Gene

Aliases for ZNF324B Gene

  • Zinc Finger Protein 324B 2 3 5

External Ids for ZNF324B Gene

Previous GeneCards Identifiers for ZNF324B Gene

  • GC19P063657
  • GC19P059047
  • GC19P059051
  • GC19P055271
  • GC19P059068
  • GC19P059080
  • GC19P059097
  • GC19P059134
  • GC19P059190
  • GC19P059230
  • GC19P059279
  • GC19P058451

Summaries for ZNF324B Gene

GeneCards Summary for ZNF324B Gene

ZNF324B (Zinc Finger Protein 324B) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF324.

UniProtKB/Swiss-Prot for ZNF324B Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF324B Gene

Genomics for ZNF324B Gene

Regulatory Elements for ZNF324B Gene

Enhancers for ZNF324B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF324B on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF324B Gene

Chromosome:
19
Start:
58,418,560 bp from pter
End:
58,457,833 bp from pter
Size:
39,274 bases
Orientation:
Plus strand

Genomic View for ZNF324B Gene

Genes around ZNF324B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF324B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF324B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF324B Gene

Proteins for ZNF324B Gene

  • Protein details for ZNF324B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6AW86-Z324B_HUMAN
    Recommended name:
    Zinc finger protein 324B
    Protein Accession:
    Q6AW86
    Secondary Accessions:
    • B2RTZ6
    • Q6ZMX8
    • Q6ZS42

    Protein attributes for ZNF324B Gene

    Size:
    544 amino acids
    Molecular mass:
    60602 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF324B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF324B Gene

Proteomics data for ZNF324B Gene at MOPED

Post-translational modifications for ZNF324B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF324B Gene

No data available for DME Specific Peptides for ZNF324B Gene

Domains & Families for ZNF324B Gene

Gene Families for ZNF324B Gene

Protein Domains for ZNF324B Gene

Suggested Antigen Peptide Sequences for ZNF324B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6AW86

UniProtKB/Swiss-Prot:

Z324B_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF324B: view

Function for ZNF324B Gene

Molecular function for ZNF324B Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF324B: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF324B Gene

Localization for ZNF324B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF324B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF324B Gene COMPARTMENTS Subcellular localization image for ZNF324B gene
Compartment Confidence
nucleus 3

No data available for Gene Ontology (GO) - Cellular Components for ZNF324B Gene

Pathways & Interactions for ZNF324B Gene

SuperPathways for ZNF324B Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF324B: view

Pathways by source for ZNF324B Gene

2 Reactome pathways for ZNF324B Gene

Interacting Proteins for ZNF324B Gene

Gene Ontology (GO) - Biological Process for ZNF324B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF324B: view

No data available for SIGNOR curated interactions for ZNF324B Gene

Drugs & Compounds for ZNF324B Gene

No Compound Related Data Available

Transcripts for ZNF324B Gene

Unigene Clusters for ZNF324B Gene

Zinc finger protein 324B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF324B Gene

No ASD Table

Relevant External Links for ZNF324B Gene

GeneLoc Exon Structure for
ZNF324B
ECgene alternative splicing isoforms for
ZNF324B

Expression for ZNF324B Gene

mRNA expression in normal human tissues for ZNF324B Gene

SOURCE GeneReport for Unigene cluster for ZNF324B Gene Hs.186970

genes like me logo Genes that share expression patterns with ZNF324B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF324B Gene

Orthologs for ZNF324B Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF324B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF324B 35
  • 98.43 (n)
  • 97.83 (a)
ZNF324B 36
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 61 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 65 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp324 36
  • 59 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 6 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii BX640547.1 36
  • 29 (a)
ManyToMany
si:dkey-199m13.2 36
  • 33 (a)
ManyToMany
si:dkey-199m13.8 36
  • 31 (a)
ManyToMany
si:dkey-233e3.4 36
  • 32 (a)
ManyToMany
si:dkey-238o14.6 36
  • 34 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta zfh1 36
  • 6 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea zag-1 36
  • 12 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 8 (a)
OneToMany
Species with no ortholog for ZNF324B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF324B Gene

ENSEMBL:
Gene Tree for ZNF324B (if available)
TreeFam:
Gene Tree for ZNF324B (if available)

Paralogs for ZNF324B Gene

Paralogs for ZNF324B Gene

(496) SIMAP similar genes for ZNF324B Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZNF324B: view

Variants for ZNF324B Gene

Sequence variations from dbSNP and Humsavar for ZNF324B Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs12611254 - 58,454,293(+) TTCCC(A/G)GTGGA reference, missense
rs7257999 -- 58,453,493(+) GAAGT(C/G)AAGAA intron-variant
rs7408188 -- 58,428,022(+) GTAGG(G/T)ATCCC intron-variant
rs7409473 -- 58,427,798(+) gccac(A/G)atcat intron-variant
rs12977592 -- 58,449,689(+) tgggg(C/G)cttta intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF324B Gene

Variant ID Type Subtype PubMed ID
nsv515731 CNV Gain+Loss 19592680
nsv833888 CNV Loss 17160897

Variation tolerance for ZNF324B Gene

Residual Variation Intolerance Score: 76.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.01; 37.01% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF324B Gene

Disorders for ZNF324B Gene

Relevant External Links for ZNF324B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF324B

No disorders were found for ZNF324B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF324B Gene

Publications for ZNF324B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa R.S. … Obuse C. (Nat. Cell Biol. 2010) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for ZNF324B Gene

Sources for ZNF324B Gene

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