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Aliases for ZNF324 Gene

Aliases for ZNF324 Gene

  • Zinc Finger Protein 324 2 3 5
  • Zinc Finger Protein ZF5128 3 4
  • ZNF324A 3 4
  • Zinc Finger Protein 324A 3
  • ZF5128 3

External Ids for ZNF324 Gene

Previous GeneCards Identifiers for ZNF324 Gene

  • GC00U990856
  • GC19P063654
  • GC19P063670
  • GC19P059042
  • GC19P059049
  • GC19P055287
  • GC19P059066
  • GC19P059081
  • GC19P059098
  • GC19P059135
  • GC19P059191
  • GC19P059231
  • GC19P059280
  • GC19P058459

Summaries for ZNF324 Gene

GeneCards Summary for ZNF324 Gene

ZNF324 (Zinc Finger Protein 324) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF324B.

UniProtKB/Swiss-Prot for ZNF324 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF324 Gene

Genomics for ZNF324 Gene

Regulatory Elements for ZNF324 Gene

Enhancers for ZNF324 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G058517 2.1 FANTOM5 Ensembl ENCODE dbSUPER 21.5 +52.7 52664 4.9 MLX CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF324B ZNF549 CENPBD1P1 MZF1 ZNF134 ZNF606 LOC100128398 ZNF324 ZBTB45 ZNF418
GH19G057818 1.3 ENCODE dbSUPER 11.6 -647.3 -647261 3.3 PKNOX1 FOXA2 CREB3L1 SIN3A ARID4B DMAP1 ZNF2 YY1 SLC30A9 ZNF143 ENSG00000269867 ZNF587 ZNF264 ZNF805 ZNF749 TRIM28 ZNF549 ZNF324 ZNF586 ZNF776
GH19G058304 1.2 ENCODE 10.7 -161.5 -161519 2.3 MLX CREB3L1 AGO1 FEZF1 DMAP1 YY1 ZNF143 SP3 NFYC TBX21 ZNF324B ERVK3-1 ZNF549 ZNF17 ZBTB45 ZNF606 MZF1 ZNF544 LOC100506634 ZNF324
GH19G057599 1.1 ENCODE 10.9 -867.0 -867008 1.5 PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 YY1 ZNF207 ZNF143 SP3 ZHX2 ZNF606 ZNF549 ZNF417 ZNF418 LOC100128398 ZNF17 ZNF773 LOC105372482 ZNF211 ENSG00000268201
GH19G058346 1 ENCODE 11.2 -119.5 -119516 1.6 HDGF PKNOX1 ATF1 CREB3L1 AGO1 SIN3A ZNF2 GLIS2 ZNF143 ZNF207 A1BG ZNF324 ZNF446 RNU6-1337P A1BG-AS1 PIR61497
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF324 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF324 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000111879 155 1201 HDGF PKNOX1 MLX CREB3L1 AGO1 ARID4B SIN3A FEZF1 DMAP1 YY1
ENSR00000111879 155 1201 HDGF PKNOX1 MLX CREB3L1 AGO1 ARID4B SIN3A FEZF1 DMAP1 YY1

Genomic Location for ZNF324 Gene

Chromosome:
19
Start:
58,467,045 bp from pter
End:
58,475,436 bp from pter
Size:
8,392 bases
Orientation:
Plus strand

Genomic View for ZNF324 Gene

Genes around ZNF324 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF324 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF324 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF324 Gene

Proteins for ZNF324 Gene

  • Protein details for ZNF324 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75467-Z324A_HUMAN
    Recommended name:
    Zinc finger protein 324A
    Protein Accession:
    O75467
    Secondary Accessions:
    • B3KRX1

    Protein attributes for ZNF324 Gene

    Size:
    553 amino acids
    Molecular mass:
    61104 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF324 Gene

Post-translational modifications for ZNF324 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF324 Gene

No data available for DME Specific Peptides for ZNF324 Gene

Domains & Families for ZNF324 Gene

Gene Families for ZNF324 Gene

Suggested Antigen Peptide Sequences for ZNF324 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O75467

UniProtKB/Swiss-Prot:

Z324A_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF324: view

Function for ZNF324 Gene

Molecular function for ZNF324 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF324 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF324: view
genes like me logo Genes that share phenotypes with ZNF324: view

Animal Model Products

CRISPR Products

miRNA for ZNF324 Gene

miRTarBase miRNAs that target ZNF324

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF324 Gene

Localization for ZNF324 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF324 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF324 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF324 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF324: view

Pathways & Interactions for ZNF324 Gene

SuperPathways for ZNF324 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF324: view

Pathways by source for ZNF324 Gene

2 Reactome pathways for ZNF324 Gene

Gene Ontology (GO) - Biological Process for ZNF324 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF324: view

No data available for SIGNOR curated interactions for ZNF324 Gene

Drugs & Compounds for ZNF324 Gene

No Compound Related Data Available

Transcripts for ZNF324 Gene

Unigene Clusters for ZNF324 Gene

Zinc finger protein 324:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF324 Gene

No ASD Table

Relevant External Links for ZNF324 Gene

GeneLoc Exon Structure for
ZNF324
ECgene alternative splicing isoforms for
ZNF324

Expression for ZNF324 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF324 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF324 Gene

This gene is overexpressed in Tlymphocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF324 Gene



Protein tissue co-expression partners for ZNF324 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF324 Gene:

ZNF324

SOURCE GeneReport for Unigene cluster for ZNF324 Gene:

Hs.515660

Evidence on tissue expression from TISSUES for ZNF324 Gene

  • Nervous system(4.6)
genes like me logo Genes that share expression patterns with ZNF324: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF324 Gene

Orthologs for ZNF324 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF324 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF324 34
  • 96.44 (n)
-- 35
  • 81 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia ZNF324 34
  • 79.75 (n)
-- 35
  • 66 (a)
OneToMany
dog
(Canis familiaris)
Mammalia ZNF324 34
  • 77.52 (n)
-- 35
  • 68 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp324 34 16 35
  • 75.89 (n)
rat
(Rattus norvegicus)
Mammalia Zfp324 34
  • 75.71 (n)
zebrafish
(Danio rerio)
Actinopterygii si:dkey-199m13.2 35
  • 34 (a)
ManyToMany
si:dkey-238o14.6 35
  • 34 (a)
ManyToMany
si:dkey-199m13.8 35
  • 32 (a)
ManyToMany
si:dkey-233e3.4 35
  • 32 (a)
ManyToMany
BX640547.1 35
  • 30 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta zfh1 35
  • 6 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea zag-1 35
  • 12 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 7 (a)
OneToMany
Species where no ortholog for ZNF324 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF324 Gene

ENSEMBL:
Gene Tree for ZNF324 (if available)
TreeFam:
Gene Tree for ZNF324 (if available)

Paralogs for ZNF324 Gene

Paralogs for ZNF324 Gene

(522) SIMAP similar genes for ZNF324 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF324: view

Variants for ZNF324 Gene

Sequence variations from dbSNP and Humsavar for ZNF324 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000441917 -- 58,467,921(+) TCCAC(C/T)GTTTG intron-variant, utr-variant-5-prime
rs1000787520 -- 58,472,452(+) ACTGC(A/G)CTGTG utr-variant-3-prime
rs1000955127 -- 58,472,706(+) CTGGG(A/T)AAGAG utr-variant-3-prime
rs1001156533 -- 58,468,776(+) CTGGT(C/T)AGGGA intron-variant
rs1001498615 -- 58,467,374(+) GCGTT(A/C)CACGT intron-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF324 Gene

Variant ID Type Subtype PubMed ID
dgv3687n100 CNV gain 25217958
esv3556698 CNV deletion 23714750
nsv1057077 CNV gain 25217958
nsv1116353 CNV deletion 24896259
nsv1160670 CNV deletion 26073780
nsv515731 CNV gain+loss 19592680
nsv833888 CNV loss 17160897
nsv952156 CNV deletion 24416366

Variation tolerance for ZNF324 Gene

Residual Variation Intolerance Score: 62.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.65; 31.56% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF324 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF324

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF324 Gene

Disorders for ZNF324 Gene

Relevant External Links for ZNF324

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF324

No disorders were found for ZNF324 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF324 Gene

Publications for ZNF324 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 64
  4. Maintenance of silent chromatin through replication requires SWI/SNF- like chromatin remodeler SMARCAD1. (PMID: 21549307) Rowbotham S.P. … Mermoud J.E. (Mol. Cell 2011) 3 64
  5. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PMID: 20360068) Hutchins J.R. … Peters J.M. (Science 2010) 3 64

Products for ZNF324 Gene

Sources for ZNF324 Gene

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