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Aliases for ZNF324 Gene

Aliases for ZNF324 Gene

  • Zinc Finger Protein 324 2 3 5
  • Zinc Finger Protein ZF5128 3 4
  • ZNF324A 3 4
  • ZF5128 3

External Ids for ZNF324 Gene

Previous GeneCards Identifiers for ZNF324 Gene

  • GC00U990856
  • GC19P063654
  • GC19P063670
  • GC19P059042
  • GC19P059049
  • GC19P055287
  • GC19P059066
  • GC19P059081
  • GC19P059098
  • GC19P059135
  • GC19P059191
  • GC19P059231
  • GC19P059280
  • GC19P058459

Summaries for ZNF324 Gene

GeneCards Summary for ZNF324 Gene

ZNF324 (Zinc Finger Protein 324) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000268163.

UniProtKB/Swiss-Prot for ZNF324 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF324 Gene

Genomics for ZNF324 Gene

Regulatory Elements for ZNF324 Gene

Enhancers for ZNF324 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF324 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF324 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF324 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF324 Gene

Chromosome:
19
Start:
58,467,045 bp from pter
End:
58,475,436 bp from pter
Size:
8,392 bases
Orientation:
Plus strand

Genomic View for ZNF324 Gene

Genes around ZNF324 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF324 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF324 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF324 Gene

Proteins for ZNF324 Gene

  • Protein details for ZNF324 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75467-Z324A_HUMAN
    Recommended name:
    Zinc finger protein 324A
    Protein Accession:
    O75467
    Secondary Accessions:
    • B3KRX1

    Protein attributes for ZNF324 Gene

    Size:
    553 amino acids
    Molecular mass:
    61104 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF324 Gene

Proteomics data for ZNF324 Gene at MOPED

Post-translational modifications for ZNF324 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF324 Gene

No data available for DME Specific Peptides for ZNF324 Gene

Domains & Families for ZNF324 Gene

Gene Families for ZNF324 Gene

Protein Domains for ZNF324 Gene

Suggested Antigen Peptide Sequences for ZNF324 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O75467

UniProtKB/Swiss-Prot:

Z324A_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF324: view

Function for ZNF324 Gene

Molecular function for ZNF324 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF324: view

Animal Model Products

CRISPR Products

miRNA for ZNF324 Gene

miRTarBase miRNAs that target ZNF324

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF324 Gene

Localization for ZNF324 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF324 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF324 Gene COMPARTMENTS Subcellular localization image for ZNF324 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF324 Gene

Pathways & Interactions for ZNF324 Gene

SuperPathways for ZNF324 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF324: view

Pathways by source for ZNF324 Gene

2 Reactome pathways for ZNF324 Gene

Interacting Proteins for ZNF324 Gene

Gene Ontology (GO) - Biological Process for ZNF324 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF324: view

No data available for SIGNOR curated interactions for ZNF324 Gene

Drugs & Compounds for ZNF324 Gene

No Compound Related Data Available

Transcripts for ZNF324 Gene

Unigene Clusters for ZNF324 Gene

Zinc finger protein 324:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF324 Gene

No ASD Table

Relevant External Links for ZNF324 Gene

GeneLoc Exon Structure for
ZNF324
ECgene alternative splicing isoforms for
ZNF324

Expression for ZNF324 Gene

mRNA expression in normal human tissues for ZNF324 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF324 Gene

This gene is overexpressed in Tlymphocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF324 Gene



SOURCE GeneReport for Unigene cluster for ZNF324 Gene Hs.515660

genes like me logo Genes that share expression patterns with ZNF324: view

Protein tissue co-expression partners for ZNF324 Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF324 Gene

Orthologs for ZNF324 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF324 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF324 35
  • 79.75 (n)
  • 75.51 (a)
-- 36
  • 66 (a)
OneToMany
dog
(Canis familiaris)
Mammalia ZNF324 35
  • 77.52 (n)
  • 76.13 (a)
-- 36
  • 68 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp324 35
  • 75.89 (n)
  • 73.08 (a)
Zfp324 16
Zfp324 36
  • 61 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia ZNF324 35
  • 96.44 (n)
  • 96.01 (a)
-- 36
  • 81 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Zfp324 35
  • 75.71 (n)
  • 72.86 (a)
zebrafish
(Danio rerio)
Actinopterygii BX640547.1 36
  • 30 (a)
ManyToMany
si:dkey-199m13.2 36
  • 34 (a)
ManyToMany
si:dkey-199m13.8 36
  • 32 (a)
ManyToMany
si:dkey-233e3.4 36
  • 32 (a)
ManyToMany
si:dkey-238o14.6 36
  • 34 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta zfh1 36
  • 6 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea zag-1 36
  • 12 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 7 (a)
OneToMany
Species with no ortholog for ZNF324:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF324 Gene

ENSEMBL:
Gene Tree for ZNF324 (if available)
TreeFam:
Gene Tree for ZNF324 (if available)

Paralogs for ZNF324 Gene

Paralogs for ZNF324 Gene

(522) SIMAP similar genes for ZNF324 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF324: view

Variants for ZNF324 Gene

Sequence variations from dbSNP and Humsavar for ZNF324 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7258608 -- 58,469,492(+) TGTCC(A/G)GCTGT intron-variant
rs1048477 -- 58,471,686(+) TTCGT(A/G)TGCGC reference, synonymous-codon
rs1048478 -- 58,471,732(+) TCTTT(A/T)AGCAC reference, stop-gained
rs1048481 -- 58,471,733(+) CTTTA(A/T)GCACC reference, missense
rs28444973 -- 58,470,677(+) CTGCC(C/T)TGGTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF324 Gene

Variant ID Type Subtype PubMed ID
nsv515731 CNV Gain+Loss 19592680
nsv833888 CNV Loss 17160897

Variation tolerance for ZNF324 Gene

Residual Variation Intolerance Score: 62.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.65; 31.56% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF324 Gene

Disorders for ZNF324 Gene

Relevant External Links for ZNF324

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF324

No disorders were found for ZNF324 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF324 Gene

Publications for ZNF324 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  4. Maintenance of silent chromatin through replication requires SWI/SNF- like chromatin remodeler SMARCAD1. (PMID: 21549307) Rowbotham S.P. … Mermoud J.E. (Mol. Cell 2011) 3
  5. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PMID: 20360068) Hutchins J.R. … Peters J.M. (Science 2010) 3

Products for ZNF324 Gene

Sources for ZNF324 Gene

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