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Aliases for ZNF320 Gene

Aliases for ZNF320 Gene

  • Zinc Finger Protein 320 2 3
  • Zinc Finger Protein Like 3
  • Zinc Finger Gene 320 3
  • ZFPL 3

External Ids for ZNF320 Gene

Summaries for ZNF320 Gene

Entrez Gene Summary for ZNF320 Gene

  • ZNF320 encodes a Kruppel-like zinc finger protein. Members of this protein family are involved in activation or repression of transcription.[supplied by OMIM, Jul 2002]

GeneCards Summary for ZNF320 Gene

ZNF320 (Zinc Finger Protein 320) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF320 Gene

  • May be involved in transcriptional regulation

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF320 Gene

Genomics for ZNF320 Gene

Genomic Location for ZNF320 Gene

Start:
52,863,790 bp from pter
End:
52,897,693 bp from pter
Size:
33,904 bases
Orientation:
Minus strand

Genomic View for ZNF320 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF320 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF320 Gene

Regulatory Elements for ZNF320 Gene

Transcription factor binding sites by QIAGEN in the ZNF320 gene promoter:

Proteins for ZNF320 Gene

  • Protein details for ZNF320 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2RRD8-ZN320_HUMAN
    Recommended name:
    Zinc finger protein 320
    Protein Accession:
    A2RRD8
    Secondary Accessions:
    • Q8NDR6

    Protein attributes for ZNF320 Gene

    Size:
    509 amino acids
    Molecular mass:
    59326 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF320 Gene

Proteomics data for ZNF320 Gene at MOPED

Post-translational modifications for ZNF320 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys274

Other Protein References for ZNF320 Gene

No data available for DME Specific Peptides for ZNF320 Gene

Domains for ZNF320 Gene

Gene Families for ZNF320 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF320 Gene

UniProtKB/Swiss-Prot:

ZN320_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • A2RRD8
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • A2RRD8
Similarity:
  • Contains 12 C2H2-type zinc fingers.:
    • A2RRD8
genes like me logo Genes that share domains with ZNF320: view

Function for ZNF320 Gene

Molecular function for ZNF320 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF320 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF320: view

miRNA for ZNF320 Gene

miRTarBase miRNAs that target ZNF320

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF320 Gene

Localization for ZNF320 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF320 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF320 Gene COMPARTMENTS Subcellular localization image for ZNF320 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF320 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF320: view

Pathways for ZNF320 Gene

SuperPathways for ZNF320 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF320: view

Pathways by source for ZNF320 Gene

2 Reactome pathways for ZNF320 Gene

Gene Ontology (GO) - Biological Process for ZNF320 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF320: view

Transcripts for ZNF320 Gene

Unigene Clusters for ZNF320 Gene

Zinc finger protein 320:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF320 Gene

No ASD Table

Relevant External Links for ZNF320 Gene

GeneLoc Exon Structure for
ZNF320
ECgene alternative splicing isoforms for
ZNF320

Expression for ZNF320 Gene

mRNA expression in normal human tissues for ZNF320 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF320 Gene

SOURCE GeneReport for Unigene cluster for ZNF320 Gene Hs.369632

mRNA Expression by UniProt/SwissProt for ZNF320 Gene

A2RRD8-ZN320_HUMAN
Tissue specificity: Expressed at high levels in placenta, pancreas, kidney and heart, and at lower levels in liver, skeletal muscle and brain.
genes like me logo Genes that share expressions with ZNF320: view

Orthologs for ZNF320 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF320 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF320 36
  • 98.95 (n)
  • 99.02 (a)
ZNF320 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 37 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 46 (a)
ManyToMany
Species with no ortholog for ZNF320:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF320 Gene

ENSEMBL:
Gene Tree for ZNF320 (if available)
TreeFam:
Gene Tree for ZNF320 (if available)

Paralogs for ZNF320 Gene

Selected SIMAP similar genes for ZNF320 Gene using alignment to 7 proteins:

Pseudogenes.org Pseudogenes for ZNF320 Gene

genes like me logo Genes that share paralogs with ZNF320: view

Variants for ZNF320 Gene

Sequence variations from dbSNP and Humsavar for ZNF320 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs7819 -- 52,876,425(-) GGTAT(G/T)TGTTC utr-variant-3-prime
rs8694 -- 52,876,497(+) TTTTT(A/T)TATTA utr-variant-3-prime
rs9148 -- 52,876,211(+) ATAAA(A/G)AAAAA utr-variant-3-prime
rs14787 -- 52,876,382(+) AAAAA(A/T)ATATC utr-variant-3-prime
rs16425 -- 52,876,444(+) AAAAC(-/AAT)GATGT cds-indel

Structural Variations from Database of Genomic Variants (DGV) for ZNF320 Gene

Variant ID Type Subtype PubMed ID
esv2718786 CNV Deletion 23290073
esv2718787 CNV Deletion 23290073
dgv3981n71 CNV Gain 21882294
esv2718796 CNV Deletion 23290073
dgv3984n71 CNV Gain 21882294
nsv833875 CNV Loss 17160897
esv2718799 CNV Deletion 23290073
nsv458747 CNV Gain 19166990
dgv3987n71 CNV Gain 21882294
nsv458752 CNV Loss 19166990
nsv524151 CNV Gain 19592680
nsv525329 CNV Loss 19592680
esv2718803 CNV Deletion 23290073
esv2718804 CNV Deletion 23290073
nsv912340 CNV Gain 21882294
esv2678383 CNV Deletion 23128226

Relevant External Links for ZNF320 Gene

HapMap Linkage Disequilibrium report
ZNF320

Disorders for ZNF320 Gene

UniProtKB/Swiss-Prot

ZN320_HUMAN
  • Note=A chromosomal aberration involving ZNF320 is found in a form of glioblastoma. Translocation t(10;19)(q26;q13.3) with BRWD2/WDR11.

Relevant External Links for ZNF320

Genetic Association Database (GAD)
ZNF320
genes like me logo Genes that share disorders with ZNF320: view

Publications for ZNF320 Gene

  1. A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells. (PMID: 11536051) Chernova O.B. … Cowell J.K. (Oncogene 2001) 2 3 4
  2. Genome-wide association study of Alzheimer's disease with psychotic symptoms. (PMID: 22005930) Hollingworth P. … Williams J. (Mol. Psychiatry 2012) 3 49
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PMID: 23000965) Povlsen L.K. … Choudhary C. (Nat. Cell Biol. 2012) 3
  5. Large-scale analysis of lysine SUMOylation by SUMO remnant immunoaffinity profiling. (PMID: 25391492) Lamoliatte F. … Thibault P. (Nat Commun 2014) 3

Products for ZNF320 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF320
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF320
    • Block miRNA regulation of ZNF320 using miScript Target Protectors

    Sources for ZNF320 Gene

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