ZNF320 Gene
protein-coding GIFtS: 44
GCID: GC19M053379
|
|
zinc finger protein 320
| |
Aliases
for ZNF320 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 3201 2 | | ZFPL1 2 | | DKFZp686G162281 | | Zinc Finger Gene 3202 | | Zinc Finger Protein Like2 |
Export aliases for ZNF320 gene to outside databasesPrevious GC identifers: GC19U990298 GC19M058071 GC19M049706 |
Summaries
for ZNF320 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZNF320:
ZNF320 encodes a Kruppel-like zinc finger protein. Members of this protein family are involved in activation orrepression of transcription.(supplied by OMIM, Jul 2002)
UniProtKB/Swiss-Prot: ZN320_HUMAN, A2RRD8Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF320 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF320 gene promoter:
Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF320
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF320 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.41 Ensembl cytogenetic band: 19q13.41 HGNC cytogenetic band: 19q13.41ZNF320 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M053379: view genomic region
(about GC identifiers)
Start:
|
53,379,425 bp from pter |
End:
|
53,394,599 bp from pter |
Size:
|
15,175 bases |
Orientation:
|
minus strand |
|
Proteins
for ZNF320 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN320_HUMAN, A2RRD8 (See
protein sequence)Recommended Name: Zinc finger protein 320 Size: 509 amino acids; 59326 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q8NDR6Explore the universe of human proteins at neXtProt for ZNF320: NX_A2RRD8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A2RRD8
ZNF320 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_997216.2
ENSEMBL proteins: ENSP00000375660 Reactome Protein details: A2RRD8
Human Recombinant Protein Products for ZNF320:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF320 for ontologies About GeneDecksing
ZNF320 Antibody Products:
Assay Products for ZNF320: |
Protein
Domains /
Families
for ZNF320 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF320 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A2RRD8ProtoNet protein and cluster: A2RRD8 UniProtKB/Swiss-Prot: ZN320_HUMAN, A2RRD8Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 12 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF320 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZN320_HUMAN, A2RRD8Function: May be involved in transcriptional regulation Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF320 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF320
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF320
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF320 (NM_207333) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF320 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF320 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF320 |
|
Pathways & Interactions
for ZNF320 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF320
ZNF320 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF320
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF320 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF320 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF320
Search CenterWatch for drugs/clinical trials and news about ZNF320 / ZN320
|
Transcripts
for ZNF320 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF320 gene: NM_207333.2 Unigene Cluster for ZNF320: Zinc finger protein 320 Hs.369632 [show with all ESTs]Unigene Representative Sequence: NM_2073331 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000391781(uc010eqi.1 uc002qag.3 uc002qah.3 uc002qai.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF320
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF320
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF320 (NM_207333) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF320 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF320 |
Additional cDNA sequence: AF086262.1 AK054877.1 AK092688.1 AK094328.1 AK095630.1 AK096348.1 AK129992.1 AK307375.1 AL831902.1 BC064408.1 BC105738.1 BC131555.1 CR933622.1 19 DOTS entries: DT.407216 DT.97846897 DT.40296649 DT.100028919 DT.102837802 DT.100666945 DT.101955610 DT.121461891 DT.95095257 DT.121462075 DT.121462154 DT.121462216 DT.92409352 DT.100670851 DT.102837803 DT.121461901 DT.91758862 DT.95081594 DT.95275975 24/40 AceView cDNA sequences (see all 40): BF475490 BE049564 BM975543 AI128698 AI279377 AA599585 AK094328 BM802632 AK096348 BE048442 AI818451 BM927044 AI806975 BM797743 AI025436 AW592967 CD240033 AI277652 N70352 BX500258 BX500263 AA844135 BU742741 BM728831
GeneLoc Exon Structure
|
Expression
for ZNF320 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF320 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for ZNF320
SOURCE GeneReport for Unigene cluster: Hs.369632
UniProtKB/Swiss-Prot: ZN320_HUMAN, A2RRD8Tissue specificity: Expressed at high levels in placenta, pancreas, kidney and heart, and at lower levels in liver,skeletal muscle and brain
SABiosciences Custom PCR Arrays for ZNF320
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF320
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF320 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF320 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF320 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF320 |
Orthologs
for ZNF320 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF320 (if available)
TreeFam Gene Tree for ZNF320 (if available) |
Paralogs
for ZNF320 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF320 gene
- ZNF5342 ZNF321P2 ZNF4682 ZNF5782 ZNF8802 ZNF7662 ZNF5252 ZNF8602
- ZNF4152 ZNF6002 ZNF282 ZNF5282 ZNF6112 ZNF6772 ZNF832 ZNF8162
- ZNF6102 ZNF7012 ZNF7652 ZNF4802 ZNF8132
18/489 SIMAP similar genes for ZNF320 using alignment to 7 protein entries: ZN320_HUMAN (see all proteins)
(see all similar genes):DKFZp686G16228 MGC12518 kr-znf3 ZNF818P ZNF888 ZNF321P
ZNF78L1 ZNF701 ZNF300P1 ZNF702P HZF36 ZFS-4
ZNF81 DKFZp686H10254 HZF30 ZFS-6 ZNF232 ZSCAN21
ZNF320 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ZNF320
PGOHUM00000250620
|
Genomic Variants
for ZNF320 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF320 (53379425 - 53394599 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF320: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF320 |
|
Disorders
/ Diseases
for ZNF320 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF320 for disorders About GeneDecksing
OMIM gene information: 606427
OMIM disorders: --
UniProtKB/Swiss-Prot: ZN320_HUMAN, A2RRD8
Note=A chromosomal aberration involving ZNF320 is found in a form of glioblastoma. Translocationt(10;19)(q26;q13.3) with BRWD2/WDR11
1  disease for ZNF320: About MalaCardsglioblastoma
Export disorders for ZNF320 gene to outside databases
|
Publications
for ZNF320 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF320 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF320) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells. (PubMed id 11536051)1, 2, 3 Chernova O.B....Cowell J.K. (2001)
- Genome-wide association study of Alzheimer's disease w ith psychotic symptoms. (PubMed id 22005930)1 Hollingworth P....Williams J. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF320 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF320 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF320 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF320 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZNF320 gene:
Search GeneIP for patents involving ZNF320
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF320 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF320 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF320 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF320 | | | OriGene Protein Over-expression Lysate for ZNF320 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF320 | | OriGene 3'-UTR Clone for ZNF320 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF320 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF320 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF320 | | OriGene Custom Protein Services for ZNF320 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF320 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF320 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF320 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF320 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF320 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF320 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF320 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ZNF320 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF320 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ZNF320 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF320 |
| |  | |
|
|
|
