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Aliases for ZNF320 Gene

Aliases for ZNF320 Gene

  • Zinc Finger Protein 320 2 3 5
  • Zinc Finger Protein Like 3
  • Zinc Finger Gene 320 3
  • ZFPL 3

External Ids for ZNF320 Gene

Previous GeneCards Identifiers for ZNF320 Gene

  • GC19U990298
  • GC19M058071
  • GC19M053379
  • GC19M049706

Summaries for ZNF320 Gene

Entrez Gene Summary for ZNF320 Gene

  • ZNF320 encodes a Kruppel-like zinc finger protein. Members of this protein family are involved in activation or repression of transcription.[supplied by OMIM, Jul 2002]

GeneCards Summary for ZNF320 Gene

ZNF320 (Zinc Finger Protein 320) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF320 Gene

  • May be involved in transcriptional regulation.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF320 Gene

Genomics for ZNF320 Gene

Regulatory Elements for ZNF320 Gene

Enhancers for ZNF320 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF320 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF320 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF320 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF320 gene promoter:

Genomic Location for ZNF320 Gene

52,863,790 bp from pter
52,897,693 bp from pter
33,904 bases
Minus strand

Genomic View for ZNF320 Gene

Genes around ZNF320 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF320 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF320 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF320 Gene

Proteins for ZNF320 Gene

  • Protein details for ZNF320 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 320
    Protein Accession:
    Secondary Accessions:
    • Q8NDR6

    Protein attributes for ZNF320 Gene

    509 amino acids
    Molecular mass:
    59326 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF320 Gene

Proteomics data for ZNF320 Gene at MOPED

Post-translational modifications for ZNF320 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF320 Gene

Domains & Families for ZNF320 Gene

Gene Families for ZNF320 Gene

Protein Domains for ZNF320 Gene

Suggested Antigen Peptide Sequences for ZNF320 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF320: view

Function for ZNF320 Gene

Molecular function for ZNF320 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF320 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZNF320: view
genes like me logo Genes that share phenotypes with ZNF320: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF320 Gene

Localization for ZNF320 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF320 Gene

Subcellular locations from

Jensen Localization Image for ZNF320 Gene COMPARTMENTS Subcellular localization image for ZNF320 gene
Compartment Confidence
nucleus 5
cytosol 3

No data available for Gene Ontology (GO) - Cellular Components for ZNF320 Gene

Pathways & Interactions for ZNF320 Gene

SuperPathways for ZNF320 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF320: view

Pathways by source for ZNF320 Gene

2 Reactome pathways for ZNF320 Gene

Gene Ontology (GO) - Biological Process for ZNF320 Gene


No data available for SIGNOR curated interactions for ZNF320 Gene

Drugs & Compounds for ZNF320 Gene

No Compound Related Data Available

Transcripts for ZNF320 Gene

Unigene Clusters for ZNF320 Gene

Zinc finger protein 320:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF320 Gene

No ASD Table

Relevant External Links for ZNF320 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF320 Gene

mRNA expression in normal human tissues for ZNF320 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF320 Gene

SOURCE GeneReport for Unigene cluster for ZNF320 Gene Hs.369632

mRNA Expression by UniProt/SwissProt for ZNF320 Gene

Tissue specificity: Expressed at high levels in placenta, pancreas, kidney and heart, and at lower levels in liver, skeletal muscle and brain.
genes like me logo Genes that share expression patterns with ZNF320: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Protein tissue co-expression partners for ZNF320 Gene

Orthologs for ZNF320 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF320 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF320 35
  • 98.95 (n)
  • 99.02 (a)
ZNF320 36
  • 99 (a)
(Bos Taurus)
Mammalia -- 36
  • 37 (a)
(Canis familiaris)
Mammalia -- 36
  • 46 (a)
Species with no ortholog for ZNF320:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF320 Gene

Gene Tree for ZNF320 (if available)
Gene Tree for ZNF320 (if available)

Paralogs for ZNF320 Gene

(510) SIMAP similar genes for ZNF320 Gene using alignment to 7 proteins: Pseudogenes for ZNF320 Gene

genes like me logo Genes that share paralogs with ZNF320: view

Variants for ZNF320 Gene

Sequence variations from dbSNP and Humsavar for ZNF320 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7256296 -- 52,886,747(+) CCTGA(A/C)CAACA intron-variant
rs7256528 -- 52,878,186(+) TGACA(A/G)TTGTA utr-variant-3-prime
rs7256753 -- 52,886,845(+) CACAA(A/G)AATCC intron-variant
rs7258006 -- 52,888,971(+) atgag(G/T)tcagc intron-variant
rs7258546 -- 52,883,627(+) ggcca(C/T)ggtgg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF320 Gene

Variant ID Type Subtype PubMed ID
esv2718786 CNV Deletion 23290073
esv2718787 CNV Deletion 23290073
dgv3981n71 CNV Gain 21882294
esv2718796 CNV Deletion 23290073
dgv3984n71 CNV Gain 21882294
nsv833875 CNV Loss 17160897
esv2718799 CNV Deletion 23290073
nsv458747 CNV Gain 19166990
dgv3987n71 CNV Gain 21882294
nsv458752 CNV Loss 19166990
nsv524151 CNV Gain 19592680
nsv525329 CNV Loss 19592680
esv2718803 CNV Deletion 23290073
esv2718804 CNV Deletion 23290073
nsv912340 CNV Gain 21882294
esv2678383 CNV Deletion 23128226

Variation tolerance for ZNF320 Gene

Residual Variation Intolerance Score: 64.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.41; 27.73% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF320 Gene

Disorders for ZNF320 Gene


  • Note=A chromosomal aberration involving ZNF320 is found in a form of glioblastoma. Translocation t(10;19)(q26;q13.3) with BRWD2/WDR11. {ECO:0000269 PubMed:11536051}.

Relevant External Links for ZNF320

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF320 Gene.

No data available for MalaCards and Genatlas for ZNF320 Gene

Publications for ZNF320 Gene

  1. A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells. (PMID: 11536051) Chernova O.B. … Cowell J.K. (Oncogene 2001) 2 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Genome-wide association study of Alzheimer's disease with psychotic symptoms. (PMID: 22005930) Hollingworth P. … Williams J. (Mol. Psychiatry 2012) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF320 Gene

Sources for ZNF320 Gene