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Aliases for ZNF32 Gene

Aliases for ZNF32 Gene

  • Zinc Finger Protein 32 2 3 5
  • Zinc Finger Protein 32 (KOX 30) 2 3
  • Zinc Finger Protein KOX30 3 4
  • C2H2-546 3 4
  • KOX30 3 4

External Ids for ZNF32 Gene

Previous GeneCards Identifiers for ZNF32 Gene

  • GC10M043428
  • GC10M043607
  • GC10M043914
  • GC10M043423
  • GC10M043338
  • GC10M043459
  • GC10M044139
  • GC10M040666

Summaries for ZNF32 Gene

GeneCards Summary for ZNF32 Gene

ZNF32 (Zinc Finger Protein 32) is a Protein Coding gene. An important paralog of this gene is ZFP1.

UniProtKB/Swiss-Prot for ZNF32 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF32 Gene

Genomics for ZNF32 Gene

Regulatory Elements for ZNF32 Gene

Enhancers for ZNF32 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10G043392 2.1 FANTOM5 Ensembl ENCODE dbSUPER 20.9 +247.2 247189 18.3 MLX CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF32 ZNF37BP LOC105378272 ENSG00000273008 BMS1 ZNF239 ZNF32-AS1 HNRNPA3P1 ZNF32-AS2 RASGEF1A
GH10G043689 1.6 FANTOM5 Ensembl ENCODE 11.5 -41.1 -41098 1.9 PKNOX1 FOXA2 ATF1 ZNF133 SIN3A ZNF2 ETS1 ZNF121 GLIS2 ELK1 ZNF32 CXCL12 PIR60234 ENSG00000228426
GH10G043605 1 ENCODE 11.3 +42.2 42217 1.7 PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 ZNF48 ETS1 GLIS2 CBX5 ZNF32 ZNF485 PIR33135
GH10G043671 0.8 ENCODE 11.6 -22.9 -22947 0.2 CTCF RB1 ZNF2 THRB RAD21 RARA SMC3 NR2F6 CREM MIXL1 ZNF32 CXCL12 LINC00619 ENSG00000228426 PIR60234
GH10G043613 0.4 ENCODE 11.4 +35.1 35050 1.3 FOS ZNF32 ZNF32-AS2 ZNF239 ENSG00000229116 ZNF485 PIR33135
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF32 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF32 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000027244 178 1800 PKNOX1 ATF1 CREB3L1 ZFP64 SIN3A ZNF48 ETS1 ZNF766 ELK1 ZNF416

Genomic Location for ZNF32 Gene

Chromosome:
10
Start:
43,643,859 bp from pter
End:
43,648,878 bp from pter
Size:
5,020 bases
Orientation:
Minus strand

Genomic View for ZNF32 Gene

Genes around ZNF32 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF32 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF32 Gene

Proteins for ZNF32 Gene

  • Protein details for ZNF32 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17041-ZNF32_HUMAN
    Recommended name:
    Zinc finger protein 32
    Protein Accession:
    P17041
    Secondary Accessions:
    • Q92951

    Protein attributes for ZNF32 Gene

    Size:
    273 amino acids
    Molecular mass:
    31029 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ZNF32 Gene

neXtProt entry for ZNF32 Gene

Post-translational modifications for ZNF32 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF32 Gene

Domains & Families for ZNF32 Gene

Gene Families for ZNF32 Gene

Protein Domains for ZNF32 Gene

Suggested Antigen Peptide Sequences for ZNF32 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P17041

UniProtKB/Swiss-Prot:

ZNF32_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF32: view

Function for ZNF32 Gene

Molecular function for ZNF32 Gene

GENATLAS Biochemistry:
zinc finger protein 32 (KOX30) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF32: view
genes like me logo Genes that share phenotypes with ZNF32: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF32 Gene

Localization for ZNF32 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF32 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF32 gene
Compartment Confidence
nucleus 5
cytosol 2
golgi apparatus 2

Gene Ontology (GO) - Cellular Components for ZNF32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF32: view

Pathways & Interactions for ZNF32 Gene

SuperPathways for ZNF32 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF32: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF32 Gene

Drugs & Compounds for ZNF32 Gene

No Compound Related Data Available

Transcripts for ZNF32 Gene

Unigene Clusters for ZNF32 Gene

Zinc finger protein 32:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF32 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c · 4d
SP1: - - - -
SP2: - - - -
SP3: - - -
SP4: - -
SP5: -

Relevant External Links for ZNF32 Gene

GeneLoc Exon Structure for
ZNF32
ECgene alternative splicing isoforms for
ZNF32

Expression for ZNF32 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF32 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF32 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (66.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF32 Gene



Protein tissue co-expression partners for ZNF32 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF32 Gene:

ZNF32

SOURCE GeneReport for Unigene cluster for ZNF32 Gene:

Hs.522885

Evidence on tissue expression from TISSUES for ZNF32 Gene

  • Nervous system(4.6)
  • Kidney(2.2)
genes like me logo Genes that share expression patterns with ZNF32: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF32 Gene

Orthologs for ZNF32 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF32 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF32 34 35
  • 99.88 (n)
dog
(Canis familiaris)
Mammalia ZNF32 34 35
  • 93.89 (n)
cow
(Bos Taurus)
Mammalia ZNF32 34 35
  • 93.77 (n)
rat
(Rattus norvegicus)
Mammalia Zfp637 34
  • 90.44 (n)
mouse
(Mus musculus)
Mammalia Zfp637 34 16 35
  • 87.99 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC100332864 34
  • 52.02 (n)
CABZ01081748.1 35
  • 42 (a)
ManyToMany
si:dkeyp-53d3.6 35
  • 40 (a)
ManyToMany
zgc:175008 35
  • 39 (a)
ManyToMany
si:dkey-77p23.2 35
  • 38 (a)
ManyToMany
CABZ01015530.1 35
  • 37 (a)
ManyToMany
CR788316.4 35
  • 37 (a)
ManyToMany
si:dkey-262g12.7 35
  • 37 (a)
ManyToMany
BX649328.1 35
  • 36 (a)
ManyToMany
si:ch211-161m3.4 35
  • 35 (a)
ManyToMany
si:ch73-266f23.3 35
  • 35 (a)
ManyToMany
si:dkey-77f5.14 35
  • 34 (a)
ManyToMany
CABZ01071909.3 35
  • 32 (a)
ManyToMany
si:dkey-240n22.8 35
  • 31 (a)
ManyToMany
si:dkey-77f5.15 35
  • 29 (a)
ManyToMany
CABZ01081749.1 35
  • 28 (a)
ManyToMany
si:ch73-57f22.2 35
  • 28 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta BG:DS02740.8 36
  • 33 (a)
CG4730 35
  • 16 (a)
ManyToMany
rgr 35
  • 9 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea M03D4.4 35
  • 15 (a)
OneToMany
Species where no ortholog for ZNF32 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF32 Gene

ENSEMBL:
Gene Tree for ZNF32 (if available)
TreeFam:
Gene Tree for ZNF32 (if available)

Paralogs for ZNF32 Gene

Paralogs for ZNF32 Gene

(552) SIMAP similar genes for ZNF32 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF32: view

Variants for ZNF32 Gene

Sequence variations from dbSNP and Humsavar for ZNF32 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000943663 -- 43,648,362(+) ACGCT(A/G)CCTGG intron-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs1001261314 -- 43,646,949(+) CCTAA(C/T)CACTA intron-variant, utr-variant-5-prime
rs1001313897 -- 43,648,560(+) CGGGC(A/C)CCGGG intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1001861571 -- 43,645,139(+) AATTT(A/G)GAAAA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1002009110 -- 43,651,340(+) ATTTG(A/G)CAGTG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF32 Gene

Variant ID Type Subtype PubMed ID
esv2437420 CNV deletion 19546169

Variation tolerance for ZNF32 Gene

Residual Variation Intolerance Score: 26.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.27; 6.13% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF32 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF32

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF32 Gene

Disorders for ZNF32 Gene

Relevant External Links for ZNF32

Genetic Association Database (GAD)
ZNF32
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF32

No disorders were found for ZNF32 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF32 Gene

Publications for ZNF32 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. C2H2-546: a zinc finger protein differentially expressed in HTLV-1 infected T cells. (PMID: 9475118) Drew P.D. … Becker K.G. (J. Neurovirol. 1997) 3 4 64
  4. Human zinc finger gene ZNF23 (Kox16) maps to a zinc finger gene cluster on chromosome 16q22, and ZNF32 (Kox30) to chromosome region 10q23-q24. (PMID: 8500793) Cannizzaro L.A. … Thiesen H.J. (Hum. Genet. 1993) 3 22 64
  5. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4 64

Products for ZNF32 Gene

Sources for ZNF32 Gene

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