ZNF319 Gene
protein-coding GIFtS: 41
GCID: GC16M058028
|
|
zinc finger protein 319
| |
Aliases
for ZNF319 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 3191 2 | | KIAA13881 3 | | Zfp3191 | | ZFP3192 |
Export aliases for ZNF319 gene to outside databasesPrevious GC identifers: GC16M058112 GC16M057763 GC16M057803 GC16M056586 GC16M043895 |
Summaries
for ZNF319 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN319_HUMAN, Q9P2F9Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF319 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF319 gene promoter:
E2F-3a E2F-4 NF-1/L NF-1 E2F-5 STAT1beta E2F-2 Egr-4 E2F-1 E2F
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF319
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF319 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q21 Ensembl cytogenetic band: 16q21 HGNC cytogenetic band: 16q21ZNF319 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M058028: view genomic region
(about GC identifiers)
Start:
|
58,028,572 bp from pter |
End:
|
58,034,357 bp from pter |
Size:
|
5,786 bases |
Orientation:
|
minus strand |
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Proteins
for ZNF319 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN319_HUMAN, Q9P2F9 (See
protein sequence)Recommended Name: Zinc finger protein 319 Size: 582 amino acids; 65547 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=BAA92626.1; Type=Erroneous initiation;
Secondary accessions: Q52LH8Explore the universe of human proteins at neXtProt for ZNF319: NX_Q9P2F9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9P2F9
ZNF319 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_065858.1
ENSEMBL proteins: ENSP00000299237 ENSP00000457048
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF319 for ontologies About GeneDecksing
ZNF319 Antibody Products:
Assay Products for ZNF319: |
Protein
Domains /
Families
for ZNF319 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF319 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9P2F9ProtoNet protein and cluster: Q9P2F9 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN319_HUMAN, Q9P2F9Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 16 C2H2-type zinc fingers |
Function
for ZNF319 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN319_HUMAN, Q9P2F9Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF319 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF319
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF319 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF319 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZNF319:
|
Pathways & Interactions
for ZNF319 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF319
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF319 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF319 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF319
Search CenterWatch for drugs/clinical trials and news about ZNF319 / ZN319
|
Transcripts
for ZNF319 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF319 gene: NM_020807.1 Unigene Cluster for ZNF319: Zinc finger protein 319 Hs.129268 [show with all ESTs]Unigene Representative Sequence: AB0378092 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000299237(uc002emx.1) ENST00000562909
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF319 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF319
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF319 (NM_020807) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF319 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF319 |
Additional cDNA sequence: AB037809.1 BC093919.1 BC101767.1 1 DOTS entry: DT.205287 24/30 AceView cDNA sequences (see all 30): BI868861 CA305905 CB266852 AA025319 AL042142 AI419755 BI915313 CB055128 AI363376 BF942296 AA024566 BQ335780 BF512889 BM468994 AB037809 AI609825 AA992676 AI362031 CB322009 BI758771 BG913813 BE046858 BG260623 CD106813
GeneLoc Exon Structure
|
Expression
for ZNF319 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF319 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCATTTTGGA
About this image
See ZNF319 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF319
SOURCE GeneReport for Unigene cluster: Hs.129268
SABiosciences Custom PCR Arrays for ZNF319
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF319
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF319 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF319 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF319 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF319 |
Orthologs
for ZNF319 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF319 gene from 5/11 species (see all 11) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Zfp3191 , 5 |
zinc finger protein 3191, 5 |
88.35(n)1
96.21(a)1 |
|
8 (47.12 cM)5
792331 NM_024467.31 NP_077787.31
953261365 |
chicken
(Gallus gallus) |
Aves |
ZNF3191 |
zinc finger protein 319 |
84.87(n)
87.16(a) |
|
427526 XM_003641887.1 XP_003641935.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ZNF3196 |
-- |
79(a) |
1 ↔ 1 |
GL343539.1(466885-468735) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.261122 |
Xenopus laevis transcribed sequence with weak similarity more |
75.35(n) |
|
CD326803.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.104072 |
Transcribed sequence with weak similarity to protein more |
77.43(n) |
|
57091988 |
ENSEMBL Gene Tree for ZNF319 (if available)
TreeFam Gene Tree for ZNF319 (if available) |
Paralogs
for ZNF319 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZNF319 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF319 (58028572 - 58034357 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF319: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF319 |
|
Disorders
/ Diseases
for ZNF319 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF319 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF319 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF319) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2, 3 Nagase T.... Ohara O. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Overexpression of a novel zinc-finger protein induces apoptosis in NIH3T3 fibroblasts. (PubMed id 11161788)1, 3 Laub F....Ramirez F. (2000)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF319 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF319 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF319 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZNF319 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF319 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF319 gene:
Search GeneIP for patents involving ZNF319
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF319 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF319 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF319 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF319 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF319 | | OriGene 3'-UTR Clone for ZNF319 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF319 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF319 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | | Search Tocris compounds for ZNF319 |
| |  |  |  |  | | | | |
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 |
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 | | | ZNF319 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF319 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF319 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF319 |
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