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Aliases for ZNF317 Gene

Aliases for ZNF317 Gene

  • Zinc Finger Protein 317 2 3
  • KIAA1588 4 6

External Ids for ZNF317 Gene

Previous GeneCards Identifiers for ZNF317 Gene

  • GC19P009372
  • GC19P009473
  • GC19P009096
  • GC19P009113
  • GC19P009115
  • GC19P009116
  • GC19P009251
  • GC19P008832

Summaries for ZNF317 Gene

GeneCards Summary for ZNF317 Gene

ZNF317 (Zinc Finger Protein 317) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF558.

UniProtKB/Swiss-Prot for ZNF317 Gene

  • May function as a transcription factor. May play an important role in erythroid maturation and lymphoid proliferation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF317 Gene

Genomics for ZNF317 Gene

Regulatory Elements for ZNF317 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF317 Gene

9,140,380 bp from pter
9,163,424 bp from pter
23,045 bases
Plus strand

Genomic View for ZNF317 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF317 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF317 Gene

Proteins for ZNF317 Gene

  • Protein details for ZNF317 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 317
    Protein Accession:
    Secondary Accessions:
    • Q6DCA9
    • Q96PM0
    • Q96PM1
    • Q96PT2
    • Q9HCI4

    Protein attributes for ZNF317 Gene

    595 amino acids
    Molecular mass:
    67959 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB13414.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF317 Gene


neXtProt entry for ZNF317 Gene

Proteomics data for ZNF317 Gene at MOPED

Post-translational modifications for ZNF317 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF317 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF317 Gene

Domains for ZNF317 Gene

Gene Families for ZNF317 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF317 Gene

Suggested Antigen Peptide Sequences for ZNF317 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q96PQ6
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF317: view

Function for ZNF317 Gene

Molecular function for ZNF317 Gene

UniProtKB/Swiss-Prot Function: May function as a transcription factor. May play an important role in erythroid maturation and lymphoid proliferation

Gene Ontology (GO) - Molecular Function for ZNF317 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 21516116
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF317: view

Phenotypes for ZNF317 Gene

GenomeRNAi human phenotypes for ZNF317:
genes like me logo Genes that share phenotypes with ZNF317: view

Animal Model Products

CRISPR Products

miRNA for ZNF317 Gene

miRTarBase miRNAs that target ZNF317

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF317 Gene

Localization for ZNF317 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF317 Gene

Subcellular locations from

Jensen Localization Image for ZNF317 Gene COMPARTMENTS Subcellular localization image for ZNF317 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF317 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IDA 21630459
genes like me logo Genes that share ontologies with ZNF317: view

Pathways for ZNF317 Gene

SuperPathways for ZNF317 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF317: view

Pathways by source for ZNF317 Gene

2 Reactome pathways for ZNF317 Gene

Gene Ontology (GO) - Biological Process for ZNF317 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF317: view

Transcripts for ZNF317 Gene

Unigene Clusters for ZNF317 Gene

Zinc finger protein 317:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF317

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF317 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d
SP1: - - -
SP2: - -
SP3: - - - - -
SP4: - - -
SP5: - - - -
SP6: - -
SP7: - - - -
SP9: - - -

Relevant External Links for ZNF317 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF317 Gene

mRNA expression in normal human tissues for ZNF317 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF317 Gene

SOURCE GeneReport for Unigene cluster for ZNF317 Gene Hs.465829

mRNA Expression by UniProt/SwissProt for ZNF317 Gene

Tissue specificity: Isoform 1 and isoform 2 are ubiquitously expressed. Isoform 3 and isoform 4 are expressed only in lymphocytes, spleen and lung.
genes like me logo Genes that share expressions with ZNF317: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ZNF317 Gene

Orthologs for ZNF317 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF317 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF317 35
  • 99.44 (n)
  • 99.16 (a)
ZNF317 36
  • 99 (a)
(Bos Taurus)
Mammalia ZNF317 35
  • 83.64 (n)
  • 87.06 (a)
ZNF317 36
  • 86 (a)
(Canis familiaris)
Mammalia ZNF317 35
  • 85.38 (n)
  • 90.08 (a)
ZNF317 36
  • 89 (a)
(Mus musculus)
Mammalia Zfp317 35
  • 79.82 (n)
  • 84.78 (a)
Zfp317 16
Zfp317 36
  • 80 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 31 (a)
-- 36
  • 36 (a)
-- 36
  • 26 (a)
-- 36
  • 23 (a)
-- 36
  • 29 (a)
-- 36
  • 38 (a)
(Rattus norvegicus)
Mammalia Zfp317 35
  • 80.15 (n)
  • 85.29 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 43 (a)
(Danio rerio)
Actinopterygii ZNF557 36
  • 35 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8388 37
  • 28 (a)
Species with no ortholog for ZNF317:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF317 Gene

Gene Tree for ZNF317 (if available)
Gene Tree for ZNF317 (if available)

Paralogs for ZNF317 Gene

Selected SIMAP similar genes for ZNF317 Gene using alignment to 3 proteins: Pseudogenes for ZNF317 Gene

genes like me logo Genes that share paralogs with ZNF317: view

Variants for ZNF317 Gene

Sequence variations from dbSNP and Humsavar for ZNF317 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs10129 -- 9,163,124(+) ACCAC(A/G)TGGGC utr-variant-3-prime, nc-transcript-variant
rs1045354 -- 9,162,624(+) ACTCT(A/C)TCATC utr-variant-3-prime, nc-transcript-variant
rs2033483 -- 9,143,666(-) TTCAA(C/T)AACTA intron-variant
rs2116861 -- 9,154,655(-) cctaa(A/T)agcca intron-variant, upstream-variant-2KB
rs2163816 -- 9,156,970(-) GAGCA(A/T)GGGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF317 Gene

Variant ID Type Subtype PubMed ID
nsv509720 CNV Insertion 20534489
nsv911020 CNV Gain 21882294
esv275448 CNV Gain+Loss 21479260
nsv2408 CNV Loss 18451855
nsv2411 CNV Loss 18451855
nsv138312 CNV Loss 16902084
nsv911021 CNV Loss 21882294
esv27422 CNV Loss 19812545

Relevant External Links for ZNF317 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF317 Gene

Disorders for ZNF317 Gene

No disorders were found for ZNF317 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF317 Gene

Publications for ZNF317 Gene

  1. Molecular cloning and characterization of a KRAB-containing zinc finger protein, ZNF317, and its isoforms. (PMID: 11688974) Takashima H. … Sawada Ki K. (Biochem. Biophys. Res. Commun. 2001) 2 3 4 23
  2. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF317 Gene

Sources for ZNF317 Gene

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