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Aliases for ZNF316 Gene

Aliases for ZNF316 Gene

  • Zinc Finger Protein 316 2 3 5
  • ENST00000305834 3
  • MZF-3 3

External Ids for ZNF316 Gene

Previous GeneCards Identifiers for ZNF316 Gene

  • GC07P006426
  • GC07U901525
  • GC07P006643
  • GC07P006676

Summaries for ZNF316 Gene

GeneCards Summary for ZNF316 Gene

ZNF316 (Zinc Finger Protein 316) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for ZNF316 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF316 Gene

Genomics for ZNF316 Gene

Regulatory Elements for ZNF316 Gene

Enhancers for ZNF316 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ZNF316 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF316 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for ZNF316 Gene

Chromosome:
7
Start:
6,637,322 bp from pter
End:
6,658,279 bp from pter
Size:
20,958 bases
Orientation:
Plus strand

Genomic View for ZNF316 Gene

Genes around ZNF316 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF316 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF316 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF316 Gene

Proteins for ZNF316 Gene

  • Protein details for ZNF316 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NFI3-ZN316_HUMAN
    Recommended name:
    Zinc finger protein 316
    Protein Accession:
    A6NFI3

    Protein attributes for ZNF316 Gene

    Size:
    1004 amino acids
    Molecular mass:
    108437 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF316 Gene

Post-translational modifications for ZNF316 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF316 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF316 Gene

Domains & Families for ZNF316 Gene

Gene Families for ZNF316 Gene

Protein Domains for ZNF316 Gene

Suggested Antigen Peptide Sequences for ZNF316 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NFI3

UniProtKB/Swiss-Prot:

ZN316_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF316: view

Function for ZNF316 Gene

Molecular function for ZNF316 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF316 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF316: view

Animal Model Products

miRNA for ZNF316 Gene

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF316 Gene

Localization for ZNF316 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF316 Gene

Gene Ontology (GO) - Cellular Components for ZNF316 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF316: view

No data available for Subcellular locations from COMPARTMENTS for ZNF316 Gene

Pathways & Interactions for ZNF316 Gene

SuperPathways for ZNF316 Gene

No Data Available

Interacting Proteins for ZNF316 Gene

Selected Interacting proteins: A6NFI3-ZN316_HUMAN for ZNF316 Gene via IID

Gene Ontology (GO) - Biological Process for ZNF316 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF316: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF316 Gene

Drugs & Compounds for ZNF316 Gene

No Compound Related Data Available

Transcripts for ZNF316 Gene

mRNA/cDNA for ZNF316 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF316 Gene

Zinc finger protein 316:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF316 Gene

No ASD Table

Relevant External Links for ZNF316 Gene

GeneLoc Exon Structure for
ZNF316
ECgene alternative splicing isoforms for
ZNF316

Expression for ZNF316 Gene

mRNA expression in normal human tissues for ZNF316 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF316 Gene

This gene is overexpressed in Prostate (29.7), CD8 Tcells (9.5), and Fetal Brain (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF316 Gene



Protein tissue co-expression partners for ZNF316 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF316 Gene:

ZNF316

SOURCE GeneReport for Unigene cluster for ZNF316 Gene:

Hs.112668
genes like me logo Genes that share expression patterns with ZNF316: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF316 Gene

Orthologs for ZNF316 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF316 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC618217 34
  • 86.33 (n)
  • 87.42 (a)
dog
(Canis familiaris)
Mammalia ZNF316 34
  • 85.08 (n)
  • 83.85 (a)
mouse
(Mus musculus)
Mammalia Zfp316 34
  • 79.3 (n)
  • 78.53 (a)
Zfp316 16
chimpanzee
(Pan troglodytes)
Mammalia LOC472281 34
  • 98.77 (n)
  • 98.88 (a)
rat
(Rattus norvegicus)
Mammalia Zfp316 34
  • 78.73 (n)
  • 78.33 (a)
Species where no ortholog for ZNF316 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF316 Gene

ENSEMBL:
Gene Tree for ZNF316 (if available)
TreeFam:
Gene Tree for ZNF316 (if available)

Paralogs for ZNF316 Gene

(237) SIMAP similar genes for ZNF316 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF316: view

No data available for Paralogs for ZNF316 Gene

Variants for ZNF316 Gene

Sequence variations from dbSNP and Humsavar for ZNF316 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs2140906 -- 6,651,613(-) GCTTT(C/T)TTTTT intron-variant
rs2140907 -- 6,646,970(-) GTCTG(A/G)AGCAT intron-variant
rs2243544 -- 6,650,639(-) CCTAG(A/G)GGGAA intron-variant
rs2249393 -- 6,657,372(+) CCCAT(C/T)TACTT utr-variant-3-prime
rs2249754 -- 6,654,874(+) ATCCC(C/G)TGGGT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF316 Gene

Variant ID Type Subtype PubMed ID
dgv1090n67 CNV gain 20364138
dgv11172n54 CNV loss 21841781
dgv11173n54 CNV loss 21841781
dgv11174n54 CNV loss 21841781
dgv11175n54 CNV loss 21841781
dgv11176n54 CNV gain 21841781
dgv11177n54 CNV loss 21841781
esv1914954 OTHER inversion 16254605
esv2752174 CNV gain 17911159
esv29317 CNV loss 19812545
esv3612040 CNV loss 21293372
nsv1020236 CNV gain 25217958
nsv1075007 CNV deletion 25765185
nsv436904 CNV insertion 17901297
nsv508444 CNV deletion 20534489
nsv515978 CNV loss 19592680
nsv606003 CNV loss 21841781
nsv606006 CNV loss 21841781
nsv606007 CNV loss 21841781
nsv606008 CNV loss 21841781
nsv606009 CNV gain 21841781
nsv606013 CNV gain+loss 21841781
nsv606019 CNV loss 21841781
nsv606027 CNV gain 21841781
nsv7392 OTHER inversion 18451855
nsv830895 CNV loss 17160897
nsv950804 CNV deletion 24416366

Relevant External Links for ZNF316 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF316

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZNF316 Gene

Disorders for ZNF316 Gene

Relevant External Links for ZNF316

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF316

No disorders were found for ZNF316 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF316 Gene

Publications for ZNF316 Gene

  1. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 3 4 65
  2. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4 65
  3. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 3 65
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65
  5. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 65

Products for ZNF316 Gene

Sources for ZNF316 Gene

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