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Aliases for ZNF316 Gene

Aliases for ZNF316 Gene

  • Zinc Finger Protein 316 2 3 5
  • MZF-3 3

External Ids for ZNF316 Gene

Previous GeneCards Identifiers for ZNF316 Gene

  • GC07P006426
  • GC07U901525
  • GC07P006643
  • GC07P006676

Summaries for ZNF316 Gene

GeneCards Summary for ZNF316 Gene

ZNF316 (Zinc Finger Protein 316) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for ZNF316 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF316 Gene

Genomics for ZNF316 Gene

Regulatory Elements for ZNF316 Gene

Enhancers for ZNF316 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G006446 1.4 ENCODE dbSUPER 19.8 -188.5 -188538 4.4 MLX CREB3L1 ZFP64 FEZF1 YY1 SLC30A9 ZNF143 ZNF263 ZNF610 GLIS1 DAGLB ZNF316 ENSG00000198580 C7orf26 ENSG00000228010 ANKRD61 KDELR2 CCZ1 USP42 RAC1
GH07G006281 1.4 Ensembl ENCODE dbSUPER 19.8 -353.8 -353760 3.8 PKNOX1 RB1 ZNF2 RAD21 GTF3C2 ZNF121 ZNF366 EGR1 ZNF143 RCOR1 ZNF316 EIF2AK1 C7orf26 ANKRD61 USP42 FAM220A CYTH3 CCZ1 GC07M006297
GH07G006372 1.4 ENCODE dbSUPER 19.8 -261.3 -261344 6.3 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A ZNF2 YY1 ZNF766 DAGLB ZNF316 C7orf26 ANKRD61 USP42 RAC1 ZDHHC4 CCZ1 PIR50924
GH07G006441 1.6 Ensembl ENCODE dbSUPER 16.9 -193.6 -193562 3.8 FOXA2 CREB3L1 ARID4B SIN3A DMAP1 YY1 ZNF143 FOS NFYC ZHX2 DAGLB ZNF316 C7orf26 USP42 ANKRD61 KDELR2 RAC1 ZNF815P ZDHHC4 GC07M006445
GH07G005687 1.9 FANTOM5 Ensembl ENCODE dbSUPER 12.7 -942.6 -942596 15.0 HDGF PKNOX1 WRNIP1 SIN3A FEZF1 YY1 TCF12 ELK1 ZNF143 FOS USP42 RNF216P1 ENSG00000198580 C7orf26 ENSG00000228010 ACTB ZNF316 FBXL18 MIR589 FSCN1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF316 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF316 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000208251 278 1601 HDGF ATF1 ARID4B SIN3A ZNF48 ZBTB7B GLIS2 CBX5 ELK1 ZNF143

Genomic Location for ZNF316 Gene

6,637,322 bp from pter
6,658,279 bp from pter
20,958 bases
Plus strand

Genomic View for ZNF316 Gene

Genes around ZNF316 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF316 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF316 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF316 Gene

Proteins for ZNF316 Gene

  • Protein details for ZNF316 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 316
    Protein Accession:

    Protein attributes for ZNF316 Gene

    1004 amino acids
    Molecular mass:
    108437 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF316 Gene

Post-translational modifications for ZNF316 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF316 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF316 Gene

Domains & Families for ZNF316 Gene

Gene Families for ZNF316 Gene

Suggested Antigen Peptide Sequences for ZNF316 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF316: view

Function for ZNF316 Gene

Molecular function for ZNF316 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF316 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF316: view

Animal Model Products

miRNA for ZNF316 Gene

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF316 Gene

Localization for ZNF316 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF316 Gene

Gene Ontology (GO) - Cellular Components for ZNF316 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF316: view

No data available for Subcellular locations from COMPARTMENTS for ZNF316 Gene

Pathways & Interactions for ZNF316 Gene

SuperPathways for ZNF316 Gene

No Data Available

Interacting Proteins for ZNF316 Gene

Selected Interacting proteins: A6NFI3-ZN316_HUMAN for ZNF316 Gene via IID

Gene Ontology (GO) - Biological Process for ZNF316 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF316: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF316 Gene

Drugs & Compounds for ZNF316 Gene

No Compound Related Data Available

Transcripts for ZNF316 Gene

mRNA/cDNA for ZNF316 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF316 Gene

Zinc finger protein 316:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF316 Gene

No ASD Table

Relevant External Links for ZNF316 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF316 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF316 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF316 Gene

This gene is overexpressed in Prostate (29.7), CD8 Tcells (9.5), and Fetal Brain (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF316 Gene

Protein tissue co-expression partners for ZNF316 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF316 Gene:


SOURCE GeneReport for Unigene cluster for ZNF316 Gene:

genes like me logo Genes that share expression patterns with ZNF316: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF316 Gene

Orthologs for ZNF316 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF316 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC472281 34
  • 98.77 (n)
(Bos Taurus)
Mammalia LOC618217 34
  • 86.33 (n)
(Canis familiaris)
Mammalia ZNF316 34
  • 85.08 (n)
(Mus musculus)
Mammalia Zfp316 34 16
  • 79.3 (n)
(Rattus norvegicus)
Mammalia Zfp316 34
  • 78.73 (n)
Species where no ortholog for ZNF316 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF316 Gene

Gene Tree for ZNF316 (if available)
Gene Tree for ZNF316 (if available)

Paralogs for ZNF316 Gene

(237) SIMAP similar genes for ZNF316 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF316: view

No data available for Paralogs for ZNF316 Gene

Variants for ZNF316 Gene

Sequence variations from dbSNP and Humsavar for ZNF316 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000187747 -- 6,648,683(+) ACACC(-/CAGA)CAGAG intron-variant
rs1000220171 -- 6,650,299(+) CTGCT(C/G/T)TGTGC intron-variant
rs1000267950 -- 6,641,460(+) CAGGG(C/G)CTAGT intron-variant
rs1000344458 -- 6,650,509(+) CCTGC(A/G)GCTCT intron-variant
rs1000519321 -- 6,646,289(+) CTCTG(G/T)TTGGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF316 Gene

Variant ID Type Subtype PubMed ID
dgv1090n67 CNV gain 20364138
dgv11172n54 CNV loss 21841781
dgv11173n54 CNV loss 21841781
dgv11174n54 CNV loss 21841781
dgv11175n54 CNV loss 21841781
dgv11176n54 CNV gain 21841781
dgv11177n54 CNV loss 21841781
esv1914954 OTHER inversion 16254605
esv2752174 CNV gain 17911159
esv29317 CNV loss 19812545
esv3612040 CNV loss 21293372
nsv1020236 CNV gain 25217958
nsv1075007 CNV deletion 25765185
nsv436904 CNV insertion 17901297
nsv508444 CNV deletion 20534489
nsv515978 CNV loss 19592680
nsv606003 CNV loss 21841781
nsv606006 CNV loss 21841781
nsv606007 CNV loss 21841781
nsv606008 CNV loss 21841781
nsv606009 CNV gain 21841781
nsv606013 CNV gain+loss 21841781
nsv606019 CNV loss 21841781
nsv606027 CNV gain 21841781
nsv7392 OTHER inversion 18451855
nsv830895 CNV loss 17160897
nsv950804 CNV deletion 24416366

Relevant External Links for ZNF316 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZNF316 Gene

Disorders for ZNF316 Gene

Relevant External Links for ZNF316

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF316 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF316 Gene

Publications for ZNF316 Gene

  1. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 3 4 64
  2. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4 64
  3. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 3 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64

Products for ZNF316 Gene

Sources for ZNF316 Gene

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