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Aliases for ZNF311 Gene

Aliases for ZNF311 Gene

  • Zinc Finger Protein 311 2 3
  • Zinc Finger Protein Zfp-31 3 4
  • Zinc Finger Protein Zfp31 3
  • ZFP31 4
  • Zf31 3

External Ids for ZNF311 Gene

Previous GeneCards Identifiers for ZNF311 Gene

  • GC06M029025
  • GC06M029070
  • GC06M028962
  • GC06M028772

Summaries for ZNF311 Gene

GeneCards Summary for ZNF311 Gene

ZNF311 (Zinc Finger Protein 311) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding.

UniProtKB/Swiss-Prot for ZNF311 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF311 Gene

Genomics for ZNF311 Gene

Regulatory Elements for ZNF311 Gene

Transcription factor binding sites by QIAGEN in the ZNF311 gene promoter:

Genomic Location for ZNF311 Gene

Chromosome:
6
Start:
28,994,785 bp from pter
End:
29,005,628 bp from pter
Size:
10,844 bases
Orientation:
Minus strand

Genomic View for ZNF311 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF311 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for ZNF311 Gene

  • Protein details for ZNF311 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JNZ3-ZN311_HUMAN
    Recommended name:
    Zinc finger protein 311
    Protein Accession:
    Q5JNZ3
    Secondary Accessions:
    • A2BFK5
    • B0S7Y4
    • Q92971

    Protein attributes for ZNF311 Gene

    Size:
    666 amino acids
    Molecular mass:
    76322 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAB16812.1; Type=Frameshift; Positions=396, 408; Evidence={ECO:0000305};

neXtProt entry for ZNF311 Gene

Proteomics data for ZNF311 Gene at MOPED

Post-translational modifications for ZNF311 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF311 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF311 Gene

Domains & Families for ZNF311 Gene

Gene Families for ZNF311 Gene

Protein Domains for ZNF311 Gene

Graphical View of Domain Structure for InterPro Entry

Q5JNZ3

UniProtKB/Swiss-Prot:

ZN311_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 14 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF311: view

Function for ZNF311 Gene

Molecular function for ZNF311 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF311 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF311: view

Phenotypes for ZNF311 Gene

GenomeRNAi human phenotypes for ZNF311:
genes like me logo Genes that share phenotypes with ZNF311: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF311

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF311 Gene

Localization for ZNF311 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF311 Gene

Gene Ontology (GO) - Cellular Components for ZNF311 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF311: view

No data available for Subcellular locations from COMPARTMENTS for ZNF311 Gene

Pathways & Interactions for ZNF311 Gene

SuperPathways for ZNF311 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF311: view

Pathways by source for ZNF311 Gene

2 Reactome pathways for ZNF311 Gene

Interacting Proteins for ZNF311 Gene

Gene Ontology (GO) - Biological Process for ZNF311 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF311: view

No data available for SIGNOR curated interactions for ZNF311 Gene

Drugs & Compounds for ZNF311 Gene

No Compound Related Data Available

Transcripts for ZNF311 Gene

mRNA/cDNA for ZNF311 Gene

Unigene Clusters for ZNF311 Gene

Zinc finger protein 311:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF311

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF311 Gene

No ASD Table

Relevant External Links for ZNF311 Gene

GeneLoc Exon Structure for
ZNF311
ECgene alternative splicing isoforms for
ZNF311

Expression for ZNF311 Gene

mRNA expression in normal human tissues for ZNF311 Gene

Protein differential expression in normal tissues from HIPED for ZNF311 Gene

This gene is overexpressed in Rectum (55.6) and Urinary Bladder (9.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF311 Gene



SOURCE GeneReport for Unigene cluster for ZNF311 Gene Hs.148218

genes like me logo Genes that share expression patterns with ZNF311: view

Protein tissue co-expression partners for ZNF311 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF311 Gene

Orthologs for ZNF311 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF311 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ZNF311 35
  • 67.75 (n)
  • 60.03 (a)
ZNF311 36
  • 56 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF311 35
  • 99.45 (n)
  • 99.1 (a)
ZNF311 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF311 36
  • 75 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta topi 36
  • 19 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea unc-98 36
  • 22 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 34 (a)
OneToOne
Species with no ortholog for ZNF311:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for ZNF311 Gene

ENSEMBL:
Gene Tree for ZNF311 (if available)
TreeFam:
Gene Tree for ZNF311 (if available)

Paralogs for ZNF311 Gene

(470) SIMAP similar genes for ZNF311 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF311: view

No data available for Paralogs for ZNF311 Gene

Variants for ZNF311 Gene

Sequence variations from dbSNP and Humsavar for ZNF311 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
VAR_031136 -
VAR_031137 -

Structural Variations from Database of Genomic Variants (DGV) for ZNF311 Gene

Variant ID Type Subtype PubMed ID
nsv830622 CNV Gain 17160897
esv2677483 CNV Deletion 23128226
esv2731756 CNV Deletion 23290073
esv2314693 CNV Deletion 18987734
esv4265 CNV Deletion 18987735
esv2609234 CNV Deletion 19546169
nsv349494 CNV Loss 16902084
esv2731757 CNV Deletion 23290073

Variation tolerance for ZNF311 Gene

Residual Variation Intolerance Score: 73.39% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.54; 55.69% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF311 Gene

HapMap Linkage Disequilibrium report
ZNF311
Human Gene Mutation Database (HGMD)
ZNF311

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF311 Gene

Disorders for ZNF311 Gene

Relevant External Links for ZNF311

Genetic Association Database (GAD)
ZNF311
Human Genome Epidemiology (HuGE) Navigator
ZNF311
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF311
genes like me logo Genes that share disorders with ZNF311: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF311 Gene

Publications for ZNF311 Gene

  1. Common variation contributes to the genetic architecture of social communication traits. (PMID: 24047820) St Pourcain B. … Smith G.D. (Mol Autism 2013) 67
  2. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos L.F. … Criswell L.A. (PLoS Genet. 2009) 67
  3. Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus. (PMID: 18309376) Lee H.S. … Gregersen P.K. (Mol. Med. 2008) 67
  4. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PMID: 17474147) Wu C. … Li S.S. (Proteomics 2007) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for ZNF311 Gene

Sources for ZNF311 Gene

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