ZNF311 Gene
protein-coding GIFtS: 46
GCID: GC06M028962
|
|
zinc finger protein 311
| |
Aliases
for ZNF311 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 3111 2 | | Zinc Finger Protein Zfp-312 3 | | Zf311 | | Zinc Finger Protein Zfp312 | | ZFP313 |
Export aliases for ZNF311 gene to outside databasesPrevious GC identifers: GC06M029025 GC06M029070 GC06M028772 |
Summaries
for ZNF311 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN311_HUMAN, Q5JNZ3Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF311 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15 NT_113891.2 NT_167244.1 NT_167245.1 NT_167246.1 NT_167248.1
- NT_167249.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF311 gene promoter:
ER-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF311
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF311 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p22.1 Ensembl cytogenetic band: 6p22.1 HGNC cytogenetic band: 6p21.33ZNF311 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M028962: view genomic region
(about GC identifiers)
Start:
|
28,962,562 bp from pter |
End:
|
28,973,093 bp from pter |
Size:
|
10,532 bases |
Orientation:
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minus strand |
6 alternative locations:
| Chr6-,ALT_REF_LOCI_1 28,962,606-28,981,382 | Chr6-,ALT_REF_LOCI_2 28,959,158-29,008,830 | Chr6-,ALT_REF_LOCI_3 28,962,576-28,984,089 | | Chr6-,ALT_REF_LOCI_6 28,962,562-29,008,618 | Chr6-,ALT_REF_LOCI_4 28,885,654-28,896,097 | Chr6-,ALT_REF_LOCI_7 28,893,045-28,903,383 | |
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Proteins
for ZNF311 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN311_HUMAN, Q5JNZ3 (See
protein sequence)Recommended Name: Zinc finger protein 311 Size: 666 amino acids; 76322 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=AAB16812.1; Type=Frameshift; Positions=396, 408;
Secondary accessions: A2BFK5 B0S7Y4 Q92971Explore the universe of human proteins at neXtProt for ZNF311: NX_Q5JNZ3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5JNZ3
ZNF311 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001010877.2
ENSEMBL proteins: ENSP00000366384 Reactome Protein details: Q5JNZ3
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF311 for ontologies About GeneDecksing
ZNF311 Antibody Products:
Assay Products for ZNF311: |
Protein
Domains /
Families
for ZNF311 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF311 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q5JNZ3ProtoNet protein and cluster: Q5JNZ3 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN311_HUMAN, Q5JNZ3Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 14 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF311 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN311_HUMAN, Q5JNZ3Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF311
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF311
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ZNF311 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF311 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF311 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF311 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF311 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF311
ZNF311 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF311
1 Interacting protein for ZNF311 (Q5JNZ33) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF311 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF311 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF311
Search CenterWatch for drugs/clinical trials and news about ZNF311 / ZN311
|
Transcripts
for ZNF311 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF311 gene: NM_001010877.2 Unigene Cluster for ZNF311: Zinc finger protein 311 Hs.148218 [show with all ESTs]Unigene Representative Sequence: AL8331662 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000377179(uc011dlk.1 uc003nlu.2) ENST00000483450(uc003nlv.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF311
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF311
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF311 (NM_001010877) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF311 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF311 |
Additional cDNA sequence: AK289881.1 AL833166.1 BC136745.1 BC144385.1 BC144386.1 U71600.1 4 DOTS entries: DT.92039091 DT.97813218 DT.425086 DT.91983711 20 AceView cDNA sequences: BM978299 CR617585 U71600 BE465817 BX350096 BX356884 AI859888 BX356883 AL833166 BX350095 BE465807 BX390337 BM665621 AI921122 AI935641 BG992896 AA969176 AW273885 AA897711 BQ343114
GeneLoc Exon Structure
|
Expression
for ZNF311 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF311 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ZNF311 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF311
SOURCE GeneReport for Unigene cluster: Hs.148218
SABiosciences Custom PCR Arrays for ZNF311
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF311
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF311 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF311 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF311 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF311 |
Orthologs
for ZNF311 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF311 gene from 1/6 species (see all 6) About this table
Species with no ortholog for ZNF311
ENSEMBL Gene Tree for ZNF311 (if available)
TreeFam Gene Tree for ZNF311 (if available) |
Paralogs
for ZNF311 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF311 gene
- CTCF2 CTCFL2 HINFP2 ZFP642
18/495 SIMAP similar genes for ZNF311 using alignment to 4 protein entries: ZN311_HUMAN (see all proteins)
(see all similar genes):ZNF300P1 ZNF721 DKFZp313M0722 ZNF232 ZNF323 ZNF78L1
DKFZp686B16128 HZF36 MGC12518 smap-7 DKFZp434J0650 HZF16
HZF30 ZFS-5 ZNF146 ZNF345 zf30 ZNF
ZNF311 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF311 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF311 (28962562 - 28973093 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for ZNF311
4 Indels: 40846 41757 12824 99476
Human Gene Mutation Database (HGMD): ZNF311
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF311 |
|
Disorders
/ Diseases
for ZNF311 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF311 for disorders About GeneDecksing
4  diseases for ZNF311: About MalaCardssystemic lupus erythematosus lupus erythematosus rheumatoid arthritis arthritis
Human Genome Epidemiology (HuGE) Navigator: ZNF311 (3 documents)
Export disorders for ZNF311 gene to outside databases
|
Publications
for ZNF311 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF311 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF311) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Computer sequence analysis of human highly conserved zinc finger modules. (PubMed id 10520746)1, 2 Petroni D.... Comi P. (1998)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1 Barcellos L.F....Criswell L.A. (2009)
- Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus. (PubMed id 18309376)1 Lee H.S....Gregersen P.K. (2008)
- Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF311 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF311 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF311 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF311 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF311 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF311 gene:
Search GeneIP for patents involving ZNF311
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF311 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF311 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF311 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF311 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF311 | | OriGene 3'-UTR Clone for ZNF311 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF311 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF311 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF311 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF311 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF311 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF311 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF311 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF311 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF311 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF311 |
|  |  |  | | | | ThermoFisher Antibodies for ZNF311 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF311 |
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