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Aliases for ZNF304 Gene

Aliases for ZNF304 Gene

  • Zinc Finger Protein 304 2 3

External Ids for ZNF304 Gene

Previous GeneCards Identifiers for ZNF304 Gene

  • GC19P058761
  • GC19P058316
  • GC19P062538
  • GC19P062554
  • GC19P057862
  • GC19P054176

Summaries for ZNF304 Gene

GeneCards Summary for ZNF304 Gene

ZNF304 (Zinc Finger Protein 304) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF304 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF304 Gene

Genomics for ZNF304 Gene

Regulatory Elements for ZNF304 Gene

Transcription factor binding sites by QIAGEN in the ZNF304 gene promoter:

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF304 Gene

57,351,277 bp from pter
57,359,898 bp from pter
8,622 bases
Plus strand

Genomic View for ZNF304 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF304 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF304 Gene

Proteins for ZNF304 Gene

  • Protein details for ZNF304 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 304
    Protein Accession:
    Secondary Accessions:

    Protein attributes for ZNF304 Gene

    659 amino acids
    Molecular mass:
    75047 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF304 Gene

Proteomics data for ZNF304 Gene at MOPED

Post-translational modifications for ZNF304 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF304 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF304 Gene

Domains for ZNF304 Gene

Gene Families for ZNF304 Gene

Suggested Antigen Peptide Sequences for ZNF304 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 16 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 16 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF304: view

Function for ZNF304 Gene

Molecular function for ZNF304 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF304 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF304: view

Phenotypes for ZNF304 Gene

GenomeRNAi human phenotypes for ZNF304:
genes like me logo Genes that share phenotypes with ZNF304: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF304 Gene

Localization for ZNF304 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF304 Gene

Subcellular locations from

Jensen Localization Image for ZNF304 Gene COMPARTMENTS Subcellular localization image for ZNF304 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF304 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF304: view

Pathways for ZNF304 Gene

SuperPathways for ZNF304 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF304: view

Pathways by source for ZNF304 Gene

2 Reactome pathways for ZNF304 Gene

Interacting Proteins for ZNF304 Gene

Gene Ontology (GO) - Biological Process for ZNF304 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF304: view

Transcripts for ZNF304 Gene

mRNA/cDNA for ZNF304 Gene

(6) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF304 Gene

Zinc finger protein 304:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF304 Gene

No ASD Table

Relevant External Links for ZNF304 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF304 Gene

mRNA expression in normal human tissues for ZNF304 Gene

Protein differential expression in normal tissues for ZNF304 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF304 Gene

SOURCE GeneReport for Unigene cluster for ZNF304 Gene Hs.287374

genes like me logo Genes that share expressions with ZNF304: view

Expression partners for ZNF304 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF304 Gene

Orthologs for ZNF304 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF304 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF304 35
  • 85.25 (n)
  • 81.69 (a)
ZNF304 36
  • 81 (a)
(Canis familiaris)
Mammalia ZNF304 35
  • 87.69 (n)
  • 85.87 (a)
ZNF304 36
  • 86 (a)
(Pan troglodytes)
Mammalia ZNF304 36
  • 89 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG2052 37
  • 31 (a)
Species with no ortholog for ZNF304:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF304 Gene

Gene Tree for ZNF304 (if available)
Gene Tree for ZNF304 (if available)

Paralogs for ZNF304 Gene

(534) SIMAP similar genes for ZNF304 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF304: view

Variants for ZNF304 Gene

Sequence variations from dbSNP and Humsavar for ZNF304 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs862698 -- 57,350,799(+) GTTAG(A/G)AAAAT upstream-variant-2KB
rs862699 -- 57,352,184(+) GGCAG(A/C)AGAGG intron-variant, upstream-variant-2KB
rs862700 -- 57,352,233(+) ATAAG(G/T)AAGGC intron-variant, upstream-variant-2KB
rs862701 -- 57,352,569(+) TGTCT(C/T)GAGTG intron-variant, upstream-variant-2KB
rs862702 -- 57,353,231(+) GTGGC(A/T)TGGGG intron-variant

Relevant External Links for ZNF304 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF304 Gene

Disorders for ZNF304 Gene

No disorders were found for ZNF304 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZNF304 Gene

Publications for ZNF304 Gene

  1. Identification of a KRAB-containing zinc finger protein, ZNF304, by AU-motif-directed display method and initial characterization in lymphocyte activation. (PMID: 12051768) Sabater L. … Dominguez O. (Biochem. Biophys. Res. Commun. 2002) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for ZNF304 Gene

Sources for ZNF304 Gene

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