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Aliases for ZNF30 Gene

Aliases for ZNF30 Gene

  • Zinc Finger Protein 30 2 3
  • Zinc Finger Protein 30 (KOX 28) 2 3
  • Zinc Finger Protein KOX28 3 4
  • KOX28 3 4
  • ZNF304 6

External Ids for ZNF30 Gene

Previous GeneCards Identifiers for ZNF30 Gene

  • GC19U990098
  • GC19M035883
  • GC19P040111
  • GC19P040112
  • GC19P040109
  • GC19P035417
  • GC19P031925

Summaries for ZNF30 Gene

GeneCards Summary for ZNF30 Gene

ZNF30 (Zinc Finger Protein 30) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF630.

UniProtKB/Swiss-Prot for ZNF30 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF30 Gene

Genomics for ZNF30 Gene

Genomic Location for ZNF30 Gene

Start:
34,926,903 bp from pter
End:
34,945,172 bp from pter
Size:
18,270 bases
Orientation:
Plus strand

Genomic View for ZNF30 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF30 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF30 Gene

No data available for Regulatory Elements for ZNF30 Gene

Proteins for ZNF30 Gene

  • Protein details for ZNF30 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17039-ZNF30_HUMAN
    Recommended name:
    Zinc finger protein 30
    Protein Accession:
    P17039
    Secondary Accessions:
    • A5PLP1
    • A8K320
    • B4DIC0
    • Q6N068

    Protein attributes for ZNF30 Gene

    Size:
    623 amino acids
    Molecular mass:
    71417 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF30 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF30 Gene

Proteomics data for ZNF30 Gene at MOPED

Post-translational modifications for ZNF30 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF30 Gene

No data available for DME Specific Peptides for ZNF30 Gene

Domains for ZNF30 Gene

Gene Families for ZNF30 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF30 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P17039

UniProtKB/Swiss-Prot:

ZNF30_HUMAN :
  • P17039
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 18 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF30: view

Function for ZNF30 Gene

Molecular function for ZNF30 Gene

GENATLAS Biochemistry: zinc finger protein 30 (KOX28) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF30: view

Phenotypes for ZNF30 Gene

GenomeRNAi human phenotypes for ZNF30:
genes like me logo Genes that share phenotypes with ZNF30: view

miRNA for ZNF30 Gene

miRTarBase miRNAs that target ZNF30

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF30 Gene

Localization for ZNF30 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF30 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF30 Gene COMPARTMENTS Subcellular localization image for ZNF30 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF30: view

Pathways for ZNF30 Gene

SuperPathways for ZNF30 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF30: view

Pathways by source for ZNF30 Gene

2 Reactome pathways for ZNF30 Gene

Interacting Proteins for ZNF30 Gene

Gene Ontology (GO) - Biological Process for ZNF30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF30: view

Transcripts for ZNF30 Gene

Unigene Clusters for ZNF30 Gene

Zinc finger protein 30:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF30 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b
SP1: - -
SP2: - -
SP3: -
SP4: -
SP5: - -

Relevant External Links for ZNF30 Gene

GeneLoc Exon Structure for
ZNF30
ECgene alternative splicing isoforms for
ZNF30

Expression for ZNF30 Gene

mRNA expression in normal human tissues for ZNF30 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF30 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (4.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF30 Gene

SOURCE GeneReport for Unigene cluster for ZNF30 Gene Hs.657402

genes like me logo Genes that share expressions with ZNF30: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF30 Gene

Orthologs for ZNF30 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF30 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF30 35
  • 98.87 (n)
  • 97.89 (a)
ZNF30 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF383 36
  • 50 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 50 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100487020 35
  • 50.72 (n)
  • 44.06 (a)
Species with no ortholog for ZNF30:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF30 Gene

ENSEMBL:
Gene Tree for ZNF30 (if available)
TreeFam:
Gene Tree for ZNF30 (if available)

Paralogs for ZNF30 Gene

Selected SIMAP similar genes for ZNF30 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF30: view

Variants for ZNF30 Gene

Sequence variations from dbSNP and Humsavar for ZNF30 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1811 - 34,943,334(+) ATGTC(A/G)GGAAT reference, missense, nc-transcript-variant
rs765746 - 34,944,165(-) ATTCA(C/T)AGGGC reference, missense, nc-transcript-variant
rs1052619 -- 34,943,117(+) ATATT(A/G)CTGAG intron-variant
rs1052621 -- 34,943,351(+) AGACC(C/T)TTTGT reference, missense, nc-transcript-variant
rs1053213 -- 34,944,872(+) TGTGT(A/G)GCTCA utr-variant-3-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF30 Gene

Variant ID Type Subtype PubMed ID
nsv523802 CNV Loss 19592680

Relevant External Links for ZNF30 Gene

HapMap Linkage Disequilibrium report
ZNF30

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF30 Gene

Disorders for ZNF30 Gene

(1) University of Copenhagen DISEASES for ZNF30 Gene

genes like me logo Genes that share disorders with ZNF30: view

No data available for UniProtKB/Swiss-Prot for ZNF30 Gene

Publications for ZNF30 Gene

  1. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for ZNF30 Gene

Sources for ZNF30 Gene

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