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Aliases for ZNF296 Gene

Aliases for ZNF296 Gene

  • Zinc Finger Protein 296 2 3
  • Zinc Finger Protein 342 2 3 4
  • ZNF342 3 4 6
  • ZFP296 3 4 6

External Ids for ZNF296 Gene

Previous HGNC Symbols for ZNF296 Gene

  • ZNF342

Previous GeneCards Identifiers for ZNF296 Gene

  • GC00U990682
  • GC19U900558
  • GC19M050267
  • GC19M045574
  • GC19M042004

Summaries for ZNF296 Gene

GeneCards Summary for ZNF296 Gene

ZNF296 (Zinc Finger Protein 296) is a Protein Coding gene. An important paralog of this gene is BCL11A.

UniProtKB/Swiss-Prot for ZNF296 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF296 Gene

Genomics for ZNF296 Gene

Regulatory Elements for ZNF296 Gene

Genomic Location for ZNF296 Gene

Start:
45,071,500 bp from pter
End:
45,076,588 bp from pter
Size:
5,089 bases
Orientation:
Minus strand

Genomic View for ZNF296 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF296 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF296 Gene

Proteins for ZNF296 Gene

  • Protein details for ZNF296 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WUU4-ZN296_HUMAN
    Recommended name:
    Zinc finger protein 296
    Protein Accession:
    Q8WUU4
    Secondary Accessions:

    Protein attributes for ZNF296 Gene

    Size:
    475 amino acids
    Molecular mass:
    50810 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF296 Gene

Proteomics data for ZNF296 Gene at MOPED

Post-translational modifications for ZNF296 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF296 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF296 Gene

Domains for ZNF296 Gene

Gene Families for ZNF296 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF296 Gene

Suggested Antigen Peptide Sequences for ZNF296 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8WUU4

UniProtKB/Swiss-Prot:

ZN296_HUMAN :
  • Q8WUU4
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 6 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF296: view

Function for ZNF296 Gene

Molecular function for ZNF296 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF296 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF296: view

Phenotypes for ZNF296 Gene

GenomeRNAi human phenotypes for ZNF296:
genes like me logo Genes that share phenotypes with ZNF296: view

miRNA for ZNF296 Gene

miRTarBase miRNAs that target ZNF296

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF296 Gene

Localization for ZNF296 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF296 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF296 Gene COMPARTMENTS Subcellular localization image for ZNF296 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF296 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF296: view

Pathways for ZNF296 Gene

SuperPathways for ZNF296 Gene

No Data Available

Interacting Proteins for ZNF296 Gene

Gene Ontology (GO) - Biological Process for ZNF296 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0007283 spermatogenesis ISS --
genes like me logo Genes that share ontologies with ZNF296: view

No data available for Pathways by source for ZNF296 Gene

Transcripts for ZNF296 Gene

mRNA/cDNA for ZNF296 Gene

(46) Selected AceView cDNA sequences:
(3) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF296 Gene

Zinc finger protein 296:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF296 Gene

No ASD Table

Relevant External Links for ZNF296 Gene

GeneLoc Exon Structure for
ZNF296
ECgene alternative splicing isoforms for
ZNF296

Expression for ZNF296 Gene

mRNA expression in normal human tissues for ZNF296 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF296 Gene

SOURCE GeneReport for Unigene cluster for ZNF296 Gene Hs.192237

genes like me logo Genes that share expressions with ZNF296: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF296 Gene

Orthologs for ZNF296 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF296 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF296 35
  • 93.86 (n)
  • 91.95 (a)
ZNF296 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF296 35
  • 84.18 (n)
  • 79.87 (a)
ZNF296 36
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF296 35
  • 85.38 (n)
  • 81.99 (a)
ZNF296 36
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp296 35
  • 73.84 (n)
  • 68.88 (a)
Zfp296 16
Zfp296 36
  • 62 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF296 36
  • 50 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp296 35
  • 73.56 (n)
  • 67.19 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 20 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii znf296 36
  • 18 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG9650 36
  • 10 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F13H6.1 36
  • 14 (a)
OneToMany
Species with no ortholog for ZNF296:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF296 Gene

ENSEMBL:
Gene Tree for ZNF296 (if available)
TreeFam:
Gene Tree for ZNF296 (if available)

Paralogs for ZNF296 Gene

Paralogs for ZNF296 Gene

Selected SIMAP similar genes for ZNF296 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF296: view

Variants for ZNF296 Gene

Sequence variations from dbSNP and Humsavar for ZNF296 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1057216 -- 45,072,450(+) GGGGC(A/C)TCCGG reference, missense
rs10408071 -- 45,073,391(+) tttga(A/G)acgga intron-variant
rs11083759 -- 45,073,456(+) agctc(C/T)gcctc intron-variant
rs28673961 -- 45,071,497(+) GACGG(C/G)TGTAA downstream-variant-500B
rs61753954 -- 45,072,405(+) ACCAC(G/T)GCCGA reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for ZNF296 Gene

Variant ID Type Subtype PubMed ID
nsv912142 CNV Loss 21882294

Relevant External Links for ZNF296 Gene

HapMap Linkage Disequilibrium report
ZNF296

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF296 Gene

Disorders for ZNF296 Gene

No disorders were found for ZNF296 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF296 Gene

Publications for ZNF296 Gene

  1. Cloning, structure, expression analysis, and assignment to mouse chromosome 7 of the gene Zfp296 encoding a zinc finger protein. (PMID: 11063263) Dear T.N. (Mamm. Genome 2000) 2 3
  2. The contribution of genetic and epigenetic mechanisms to gene silencing in oligodendrogliomas. (PMID: 14633674) Hong C. … Costello J.F. (Cancer Res. 2003) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Overexpression of ZNF342 by juxtaposition with MPO promoter/enhancer in the novel translocation t(17;19)(q23;q13.32) in pediatric acute myeloid leukemia and analysis of ZNF342 expression in leukemia. (PMID: 19255975) Poland K.S. … Plon S.E. (Genes Chromosomes Cancer 2009) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF296 Gene

Sources for ZNF296 Gene

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